Growing "Mini-Brains" in a Lab: Human Brain Organoids

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  • เผยแพร่เมื่อ 21 ม.ค. 2025

ความคิดเห็น • 266

  • @ghostagent3552
    @ghostagent3552 2 ปีที่แล้ว +61

    watching this video is like watching the beginning of a scifi movie and will be followed by some conscious tumors invasion

    • @ihmcurious
      @ihmcurious  2 ปีที่แล้ว +3

      lol sounds kinda cute

    • @ghostagent3552
      @ghostagent3552 2 ปีที่แล้ว +3

      @@ihmcurious is it really cute if it's more like the THING or something along the lines of flesh monsters from Gemini Home Entertainment?

    • @ihmcurious
      @ihmcurious  2 ปีที่แล้ว +9

      I was picturing little meatwads from aqua teen hunger force. Maybe the alternatives aren't so cute...

  • @dogchaser520
    @dogchaser520 2 ปีที่แล้ว +92

    Thanks for taking the time to break down the research for non-specialists. This stuff is pretty challenging to synthesize all together. Really enjoying what you've put out so far.

  • @Ossian-dr1vr
    @Ossian-dr1vr 2 ปีที่แล้ว +52

    Wait I just checked and somehow you only have 1650 subscriber!? I thought this channel for sure had AT LEAST 500 000 because of the cheer video quality and interesting subject. Why youtube doesn't recommend this to more people really is beyond me. Good luck man and keep it up!

    • @andrewthorpe3377
      @andrewthorpe3377 2 ปีที่แล้ว

      He's at 6.27k now. The channel only has 7 videos. I'm sure it will continue growing as he makes more.

    • @acsilver2777
      @acsilver2777 2 ปีที่แล้ว

      @@andrewthorpe3377 6.4 now looks like the algorithm is doing its job for once. So glad I found this channel

    • @deweytann
      @deweytann 2 ปีที่แล้ว +1

      8.9k now it's growing like a Organoid!

    • @jdorchen
      @jdorchen 3 หลายเดือนก่อน

      up to 39.7k now

  • @Anaesify
    @Anaesify 2 ปีที่แล้ว +50

    I just stumbled upon you as a creator and you are DELIGHTFUL! I love your deadpan joke delivery and the facts and info in your vids are top notch

    • @nicandkiritos22
      @nicandkiritos22 7 หลายเดือนก่อน

      Agreed, jokes delightful,and interesting facts. But I have to say I had a pet rat,...he already had fear response and voice recognition and all those natural things, but placing a mini brain in side would only lead to unnatural " crazy " behavior, and a rejection of the intruder cells. Whatever photoreceptors genes I have make me grimace at light and develope skin cancer, it is suffering , and I can't condone that.

  • @andreas7812
    @andreas7812 3 ปีที่แล้ว +85

    This is very interesting and your videos holds very good quality. I hope this channel will grow because it deserves it. 😀

  • @Gounesh
    @Gounesh 2 ปีที่แล้ว +9

    How come this videos not discovered?! This is awesome!

  • @metamind095
    @metamind095 ปีที่แล้ว +2

    You really digged deep here. From IPS cell reprogramming, lab cultured meat, disease modifying aspects of custom brain organoids, plasticity change with plastinogens also analogies you presented here like snow-flake structure change of organoids, larger coneectivity status hinting to higher "consiousness" etc. all neatly wrapped with some philosophical explorations and ofc your on-point humour just keeps me engaged in the topic. Hardly have seen anything quite like it with that amount of papers linked (LOVE THIS ASPECT!) in an easy to consume presentation. I really hope you stick to this formular and dont kneel in to youtubes quantity over quality algorithm (at least thats what it feels for me). Patreoned btw.

  • @The_Carmine
    @The_Carmine ปีที่แล้ว +3

    paved with good intentions.

  • @ibowman_UCLA_BRAIN
    @ibowman_UCLA_BRAIN 2 ปีที่แล้ว +4

    You have an incredible ability to distill the most relevant neurobio/neurology/neurowhatever (also bioengineering) topics into a concise and interesting presentation. Please keep it up.

  • @radiofrog
    @radiofrog 2 ปีที่แล้ว +5

    What an incredibly interesting and terrifying concept. I’m surprised you don’t have more subscribers, this is really high quality stuff. Great work!

  • @mateusmachadofotografia8554
    @mateusmachadofotografia8554 3 หลายเดือนก่อน +1

    I really like your type of humor! I learned a lot here, thanks

  • @quintennobbe
    @quintennobbe 2 ปีที่แล้ว +10

    This is amazing!!! I love your content! wow this guys needs more subs

    • @quintennobbe
      @quintennobbe 2 ปีที่แล้ว

      you have my sub and like and share

  • @llammapajama4824
    @llammapajama4824 2 ปีที่แล้ว +3

    Cool videos. Glad I got recommended them. Definitely subbed

  • @dogwithsocks
    @dogwithsocks 2 ปีที่แล้ว +1

    TH-cam did something right this time. I’ve always wondered about this topic. You got me dude!

  • @proxicat123
    @proxicat123 2 ปีที่แล้ว +1

    This channel is the perfect mixture of humour and science bro, love it

  • @Snookenu
    @Snookenu 6 หลายเดือนก่อน

    Just realized this video has 40 000 videos. Have watched alot of your videos and always thought they had a couple million views. Never checked the view and subscriver count till now. Really cool content, i subscribed.

  • @ekeredtv
    @ekeredtv 2 ปีที่แล้ว

    Your deadpan humour is really well delivered.

  • @oxlip
    @oxlip 2 ปีที่แล้ว +2

    This channel is so good bro you deserve way more subscribers than you have

  • @ryansmith4213
    @ryansmith4213 2 ปีที่แล้ว +2

    Great video! I hope all these recent comments means you caught the algorithm, because this is really entertaining and informative!

  • @vaneplane
    @vaneplane ปีที่แล้ว +2

    I love how your videos are funny and easy to understand, keep up the great work!

  • @adram3lech
    @adram3lech 2 ปีที่แล้ว +1

    Hey man happy to find your channel! Can't believe I've never heard of any of this

  • @amitvashishtha8713
    @amitvashishtha8713 2 ปีที่แล้ว +2

    Every line is just a wow!! 😮

  • @mortyrickerson6322
    @mortyrickerson6322 2 ปีที่แล้ว +1

    Sorry for blowing up your inbox 😅 just binging your vids. Gotta leave a comment for the algorithm Gods. Cheers

  • @BettersonMcgee
    @BettersonMcgee 2 ปีที่แล้ว +1

    Glad i found this channel! Exactly the kind of stuff i love! You present the info very well without compromising on the information. Love it!

  • @KickCaesar
    @KickCaesar 2 ปีที่แล้ว

    man, I'm happy I got this channel recommended this is the type of research I like!!

  • @localwan
    @localwan 2 ปีที่แล้ว +2

    very engaging and high quality video.

  • @prakamyakhare7505
    @prakamyakhare7505 2 ปีที่แล้ว +2

    This channel is a gem :).

  • @tristanmisja
    @tristanmisja 2 ปีที่แล้ว +2

    I saw that subliminal message! Great video, you deserve way more than 2k subs.

    • @unikracoon1913
      @unikracoon1913 2 ปีที่แล้ว

      What was typed out. I didn't bother pausing haha

    • @tristanmisja
      @tristanmisja 2 ปีที่แล้ว +1

      @@unikracoon1913 "It's not subliminal if you read it"

    • @unikracoon1913
      @unikracoon1913 2 ปีที่แล้ว

      @@tristanmisja thx haha

  • @INHIAF
    @INHIAF 3 ปีที่แล้ว +3

    Damn this editing next level🔥🔥

  • @Sxzye
    @Sxzye 2 ปีที่แล้ว

    Leaving this comment for the algorithm, this content is definitely deserving of millions of views

  • @PaulWolf-t2h
    @PaulWolf-t2h 5 หลายเดือนก่อน +2

    I'm a lawyer. Maybe someday I can get one of these guys as a client and defend their rights in court.

  • @amitvashishtha8713
    @amitvashishtha8713 2 ปีที่แล้ว +2

    Very deep knowledge 🙏👏... Please upload regular content.. U should be a success youtuber... ❤

  • @Premo-412
    @Premo-412 11 หลายเดือนก่อน +1

    This vid is awesome man!

  • @Quazex
    @Quazex 2 ปีที่แล้ว +22

    I'm usually more into cybernetics but this stuff is cool as hell. Awesome that we're able to do this.

    • @subspanner
      @subspanner 2 ปีที่แล้ว +2

      @Invisibility Lock That's what I thought, along with the possibility to replace parts of our brain or even advance them.

    • @tehdawson
      @tehdawson 2 ปีที่แล้ว +2

      @@Invisibilitylock I think it will be in our lifetimes.

    • @alanp741
      @alanp741 7 หลายเดือนก่อน

      i think the use of these organoids could actually help with the work on cybernetics as a middle ground between the digital to the analog

  • @anthonymetcalf660
    @anthonymetcalf660 2 ปีที่แล้ว +1

    Fantastic presentation, jokes on point and highly informative an insightful

  • @just1it1moko
    @just1it1moko 2 ปีที่แล้ว +13

    Imagine a future where you could just get a new organ transplant. Either growing them or replacing them with synthetic organs I'm 100% convinced it'll become commonplace in my lifetime.
    I know temporary organs exist right now a friend of mine lived 2 months with a synthetic heart which was the size of a small cupboard next to his hospital bed.
    And some things like heartvalves are already being made in labs to replace those that show dysfunction.
    Just imagine. you start getting older your organs start to get worse and worse and you just get a new one in increasing your life expectancy by years! at that point I think the brain is gonna be the toughest nut to crack and I don't see us being able to heal/replace them partially or fully.
    Also that would just create the philosophical debate of the "brain of Theseus".

  • @SuperDuperSigmaMale
    @SuperDuperSigmaMale ปีที่แล้ว +2

    Man i cant wait for the medical science advancements this will bring with the help of a few brilliant minds.

  • @CanineWolf
    @CanineWolf 2 ปีที่แล้ว +1

    Wow, very good quality content!!!

  • @saijeetdogra9360
    @saijeetdogra9360 ปีที่แล้ว +2

    "The authors were disappointed that they started dying after 60 days"
    Poor authors rip 🙏

  • @daevastafford
    @daevastafford 2 ปีที่แล้ว

    ... 💀 This channel is so underrated... Wtf, this is my new favourite place bruh 😭✋

  • @bnichoo
    @bnichoo ปีที่แล้ว

    It only took me a couple minutes to subscribe to the channel, incredible stuffs all over

  • @kaorudragneel8498
    @kaorudragneel8498 3 ปีที่แล้ว +18

    That's terrifying I love it but has some place for good

  • @fasaipuengudom5412
    @fasaipuengudom5412 2 ปีที่แล้ว

    New sub. 🎉
    Watched til the end. Twice.
    Thank for creating great contents.

  • @AssetH8ut2
    @AssetH8ut2 ปีที่แล้ว

    Wow, a good video; it’s been awhile.

  • @weeferooni
    @weeferooni 2 ปีที่แล้ว +3

    to all the brains out there in test tubes wondering why the fuck its so dark all of the time and why youre so bored: i just want you to know i feel you.

  • @izenlonghurst4589
    @izenlonghurst4589 2 ปีที่แล้ว

    Fantastic video, can't wait to see your video on psychedelics in medicine

  • @RobotischeHilfe
    @RobotischeHilfe 2 ปีที่แล้ว

    U got my sub, great channel very Interesting and very entertaining easy to understand. Please keep that quality

  • @ZER0x1337
    @ZER0x1337 2 ปีที่แล้ว +4

    ok guys i think we are flying a littttleeee too close to the sun rn.

  • @Sunneyred
    @Sunneyred 2 ปีที่แล้ว

    Funny asf and informal, earned my sub!

  • @f-149
    @f-149 2 ปีที่แล้ว +1

    everybody gangsta till the mouse starts saying its name is john

  • @chrisgraham2123
    @chrisgraham2123 7 หลายเดือนก่อน

    Good content, subbed brother

  • @boratbruno4947
    @boratbruno4947 2 ปีที่แล้ว

    How doesn’t this have millions of views?

  • @whatisthis839
    @whatisthis839 2 ปีที่แล้ว +2

    This channel has tons of potential, apparently the algorithm agrees. Awesome video. Actually funny host. Interesting subject. Profound philosophical questions. Existential dread. Excellent.

  • @BeyondBorders00
    @BeyondBorders00 ปีที่แล้ว

    I would love to hear more about brain organoids and in vitro neurons used for calculation. For example, Dishbrain from Cortical Labs in Australia. There are a number of university research groups also using neurons either in organoid form or in vitro to perform calculations and solve problems. Please cover this topic

  • @gemerpyros
    @gemerpyros 2 ปีที่แล้ว

    wow wtf this video is amazing. I had to share it

  • @ginger_jake
    @ginger_jake 2 ปีที่แล้ว

    Had to pause half way through this vid to subscribe and comment ok omw back to learning about mini eyes on a dish brain wish me luck weeew

  • @dkt5679
    @dkt5679 8 หลายเดือนก่อน

    Great video! Subscribed :)

  • @PedanticNo1
    @PedanticNo1 2 ปีที่แล้ว

    I have engaged, and am therefore become the engagement.

  • @cadechristopher6456
    @cadechristopher6456 2 ปีที่แล้ว

    I love this channel. 👍

  • @johnr3936
    @johnr3936 2 ปีที่แล้ว +1

    You are genuinely hilarious!

  • @JubulusPrime
    @JubulusPrime 2 หลายเดือนก่อน +1

    7:35 It just says "It's not subliminal if you read it!"

  • @Luchoedge
    @Luchoedge 2 ปีที่แล้ว +12

    People fucking around with human neurons and mice should really watch a particular episode of full metal alchemist. Just saying...

  • @ctoasa
    @ctoasa ปีที่แล้ว

    Wao que increíble. Gracias por la información.

  • @khade12345
    @khade12345 2 ปีที่แล้ว

    This is so good

  • @maxpowers802
    @maxpowers802 2 ปีที่แล้ว +38

    they should try putting human brain tissue in an animal that can talk, like a parrot. That way it could tell us what it's like.

    • @maneki360nekodude5
      @maneki360nekodude5 2 ปีที่แล้ว +4

      Add some human vocal cords as well while we are at it .

    • @20ZZ20
      @20ZZ20 2 ปีที่แล้ว +7

      parrots don't really talk in that way, and don't use language the same as a human although they mimic

    • @maxpowers802
      @maxpowers802 2 ปีที่แล้ว +8

      @@20ZZ20 Only because they don't have enough human brain tissue

    • @Faunarr
      @Faunarr 2 ปีที่แล้ว +8

      parrots are a terrible idea. Because they don't process language in the same way we do and said sounds to them are essentially just things they could mimic and attract mates with.
      If you really want to go that route how about corvids? corvids are much more intelligent and have the capability of learning a language to a limited extent and can communicate with it to a limited extent. a corvid such as a crow or raven would be far more suitable for your idea.

    • @20ZZ20
      @20ZZ20 2 ปีที่แล้ว +3

      @@maxpowers802 not really.... parrots replicate human voices the same way in the wild they try to replicate other sounds, they won't suddenly understand grammar etc. and start speaking procedurally with some extra brain

  • @AssetH8ut2
    @AssetH8ut2 ปีที่แล้ว

    Would love this for my non profit college for vets.

  • @lexflow2319
    @lexflow2319 2 ปีที่แล้ว

    Dope channel

  • @stiffori
    @stiffori 11 หลายเดือนก่อน +1

    When the horrors become within human comprehension

  • @facelessdrone
    @facelessdrone ปีที่แล้ว

    For those wondering what the image flashed at 7:38 says, it says "It's not subliminal if you read it!"

  • @jaykay639
    @jaykay639 2 ปีที่แล้ว +1

    GO BIG MODE

  • @XcaliburZeRo
    @XcaliburZeRo 2 ปีที่แล้ว +5

    This is amazing, everyone.. but isn't there a slight dystopian hint to all of this at the same time? What a time to be alive. They even dosed those mini-brains with 5-MeO-DMT... interesting.

    • @MrCrunch808
      @MrCrunch808 ปีที่แล้ว +1

      If this tech gets advanced enough that it becomes possible to send data and have it process that data and coherently output what we want, I wouldn't be surprised if some companies decide to create consciousnesses that think and feel and then enslave them without a care in the world to power their AI (which is really just a bunch of people at that point.).

  • @bryantbribiesca
    @bryantbribiesca 3 หลายเดือนก่อน +1

    What came first chicken or the egg? Organiods.

  • @CyborgHGWF
    @CyborgHGWF ปีที่แล้ว

    13:04 Lol Mouse overloards lol.. right on

  • @CabalisOrder
    @CabalisOrder ปีที่แล้ว +1

    100 years ago ... they build a Computer without Monitor ... !!!
    ... makes me think

  • @davion9402
    @davion9402 6 หลายเดือนก่อน

    Is it subliminal if its in chinese brail and upside down with my left hand?

  • @jonahvimeo4276
    @jonahvimeo4276 6 หลายเดือนก่อน

    good made video - up 👍

  • @masonjohn4433
    @masonjohn4433 2 ปีที่แล้ว +1

    This guy is hilarious!

  • @VEVOJavier
    @VEVOJavier ปีที่แล้ว

    Please make more videos!

  • @matasvitkauskas7541
    @matasvitkauskas7541 2 ปีที่แล้ว

    amazing

  • @ThankyouDeer029
    @ThankyouDeer029 2 ปีที่แล้ว +1

    do you think it would be possible to create an organoid that you could put into your brain that allows you to control every single part of your body even the itty bitty parts like cells?

    • @iaimboti
      @iaimboti ปีที่แล้ว +2

      Maybe, depends on how much the brain controls, but I assume that would be a really bad idea unless you really knew what you were doing.

  • @Usakumi
    @Usakumi 2 ปีที่แล้ว

    nice vid

  • @pepeshackleford4577
    @pepeshackleford4577 2 ปีที่แล้ว +1

    Expected this video to have at least a million views. I'm so confused

  • @handlethissonny
    @handlethissonny ปีที่แล้ว +1

    dude cool content

  • @familjenlover6827
    @familjenlover6827 8 หลายเดือนก่อน

    how long until we can put these in roombas?

  • @Neon-ws8er
    @Neon-ws8er 2 ปีที่แล้ว +2

    wouldn’t it be cool to grow a baby brain and have it control your toaster for you

  • @TheRealityWarper08
    @TheRealityWarper08 2 ปีที่แล้ว +1

    This is horrifying...
    Give me more...

  • @BreadBecause
    @BreadBecause 10 หลายเดือนก่อน +1

    The real question here:
    Can it play DOOM?

  • @CD3WD-Project
    @CD3WD-Project ปีที่แล้ว

    How is it not a subliminal message if I do read it I would think that it would still be a subliminal message as there might be undertones in the message. So what was that 1 frame?

    • @ihmcurious
      @ihmcurious  ปีที่แล้ว

      The written message is only subliminal if you are not consciously reading it. If you consciously read it, it becomes supraliminal, meaning "above the threshold" of conscious awareness. You could perceive something subliminally while you are perceiving something else supraliminally, but I didn't go that far.

    • @CD3WD-Project
      @CD3WD-Project ปีที่แล้ว

      @@ihmcurious oh I was just joking. I had to comment when I saw what you did. Anyway good show you have.

  • @Kadeshy
    @Kadeshy 2 ปีที่แล้ว

    what`s the easter egg? I saw it passing, but never reached the frame

  • @bartlomiejkowalczyk4673
    @bartlomiejkowalczyk4673 2 ปีที่แล้ว +2

    8:07 lol its pentagram

  • @CyborgHGWF
    @CyborgHGWF ปีที่แล้ว

    07:37 saw that .. wow

  • @MrCrunch808
    @MrCrunch808 ปีที่แล้ว +7

    Ah, the beginnings of man-made horrors fully within my comprehension.

  • @damianbouras
    @damianbouras ปีที่แล้ว +3

    I don't see conciousness as a nescesity for this to be imhumane. who's to say we don't excedentally create a minibrain that's just 99 percent suffering. considering most emotions, especially primal ones like fear or pain, are primarily processed by relatively small parts of the brain, it's not really that far fetched to think that one of these things might just excedentally be isolated human fear. I think that's maybe even worse than consciousness.

    • @reizayin
      @reizayin 2 หลายเดือนก่อน

      that's horrific and hilarious

  • @wormius51
    @wormius51 ปีที่แล้ว

    "It's not subliminal if you read it!" Dam it took me long to capture that.

  • @Bigzthegreat
    @Bigzthegreat 2 ปีที่แล้ว

    so interesting

  • @JoBot__
    @JoBot__ ปีที่แล้ว

    This is awesome and horrifying at the same time. I love it. 😃

  • @martinwinther6013
    @martinwinther6013 2 ปีที่แล้ว

    algo-jazz, cus YT.
    and this channel needs 7.6m subscribers. yesterday

  • @harshad3767
    @harshad3767 2 ปีที่แล้ว

    10:53..... "Breaking News (2210) : Scientist Are Testing on sentient suit which looks like VENOM "

  • @Warhawk76
    @Warhawk76 2 ปีที่แล้ว

    "...can't explain why he's still so annoying." Classic humor, I love it!

  • @tuckersabath2099
    @tuckersabath2099 2 ปีที่แล้ว +1

    Of all the places that brain cells could grow, where most of us find ourselves isnt that bad.

    • @tuckersabath2099
      @tuckersabath2099 2 ปีที่แล้ว

      ... and 11:50 was obviously dark humor, right?