Warburg Effect | Nobel Prize | PET CT

In oncology, the Warburg effect is the observation that most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol, rather than by a comparatively low rate of glycolysis followed by oxidation of pyruvate in mitochondria as in most normal cells. This observation was first made by Nobel laureate Otto Heinrich Warburg who was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme".
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[@rgh2164]

The energy produced by 36 ATPS is not utilised fully by the normal cell. Some part of the energy is converted into heat, a waste product. But though a waste product, it is very essential for sustaining the functioning of the normal cell. In cancer cells this heat sustenance is on a very low scale due to only 2 ATPs produced in aerobic glycolysis. Thus cancer cells become heat starved or they maintain low heat profile. Because of low heat profile, normal functioning in cancer cells is disrupted and their mitochondria stop producing ATPs required for heat sustenance of cancer cells.

[@rodrigomontero7777]

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[@SisterKristen]

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[@lisareed9296]

Do you mean anaerobic ( instead of aerobic)?

[@potptvpatsonthepulse5701]

i had the same thought

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[@Hesbonful]

Get to the point please ... did not finish video.

[@Justin.Martyr]

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[@cemiliyaxalil1842]

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[@johnmgee8249]

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[@cemiliyaxalil1842]

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