Very good video. It demonstrates how many moving parts are involved in cancer and why most drugs fail to control it. We just do not know enough of the incredible complexity involved in cancer development
I found this video extremely helpful, it has provided a basis about signaling within a cell. I would recommend this video to someone wanting to brush up on intracellular signaling.
umm --the video says that overexpression of Growth factor receptors causes ligand independent firing - id look over that one more time Its more likely structural mutations to the tyrosine kinase receptor cause ligand-independant activation while overexpression, on the other hand, causes hyper proliferation in basal levels of growth factor
When the receptors are over expressed, the Monomers of receptor tyrosin kinases will interact with each other due to the abundance of the receptors on the plasma membrane. Thus, the overexpression of the receptor will lead to the activation of these receptors by each other by means of transphosphorylation(biochemically speaking-biologically speaking autophosphorylation), giving the cell an oncogenic power.making the cell mitotically active irresepective of the ligand presence. (ligand independent firing).
+Yessi Perez ... or at least a way to tame and regulate cancers. Sometimes a mass of fast-replicating cells can come in handy, but we would still need a way to tell them when and where to stop or slow down, and tell them not to metastasize.
Seems to me like a promotional video of how well they are doing. Which is fine even if it's not true. But not fine if, "not true", holds up some other research which is.
Ah yes of course, I understood everything.
*rewinding intensifies*
Very good video. It demonstrates how many moving parts are involved in cancer and why most drugs fail to control it. We just do not know enough of the incredible complexity involved in cancer development
This was just a great video !!! thanks for editing, producing and thanks for people on sharing!
pretty dope series about the cancer mechanism! trully enjoyed it.
Amazing high quality video!!! Thanks so very much for creating it!
this is just EPIC and extremely awesome , i really can`t tell how i loved that series . excellent work INDEED
I found this video extremely helpful, it has provided a basis about signaling within a cell.
I would recommend this video to someone wanting to brush up on intracellular signaling.
Excellent video! Now THIS is a good way to learn. Keep up the good work :)
Very good explanation
Thank you for this amazing and very pratical vidéo.
extremely instructive...thank you
Yes Yes Yes Sir💖💖💖 GooooooD 💚💚
ultimate and outstanding video.
Thanks a lot! Excellent video!
Great video
Very good! I was able to learn more
Awesome explanation :-)
Thanks 👍👍
Where can I find transduction pathways associated directly with gene expression and regulation?
Transforming Growth Factor Alpha, Not Tumor Growth Factor Alpha. Tumor Growth Factor Beta, Transforming Growth Factor Alpha.
Thank you for a great video
very very very well explanation
super nice video!!
superv explaination :)
great vid
Fabulous
Nice video, it explains how the body can heal itself if we give them good balanced nutrition.
Thanks! uploader
thank you
nice one
thank you so much
thank u soo much.......
Great.
great !!!
The animation is way too good.
The animation is excellent and the explanation are clear but very unstructured. It was hard to take notes while watching
Can someone please suggest some good introduction textbooks about general cancer biology?
thank u
Introduction to Cancer Biology (Part 1): Abnormal Signal Transduction
Great!
awsome
❤❤
umm --the video says that overexpression of Growth factor receptors causes ligand independent firing - id look over that one more time
Its more likely structural mutations to the tyrosine kinase receptor cause ligand-independant activation while overexpression, on the other hand, causes hyper proliferation in basal levels of growth factor
When the receptors are over expressed, the Monomers of receptor tyrosin kinases will interact with each other due to the abundance of the receptors on the plasma membrane.
Thus, the overexpression of the receptor will lead to the activation of these receptors by each other by means of transphosphorylation(biochemically speaking-biologically speaking autophosphorylation), giving the cell an oncogenic power.making the cell mitotically active irresepective of the ligand presence. (ligand independent firing).
I hope someone finds a cure some day
+Yessi Perez ... or at least a way to tame and regulate cancers. Sometimes a mass of fast-replicating cells can come in handy, but we would still need a way to tell them when and where to stop or slow down, and tell them not to metastasize.
Trinitrophenylnitramine just stop eating anything
Interesting
When your lecturer is useless... go to youtube >,
can anyone let me know, what does he say in the 50th minutes? solid .... molecules,
thank you
"...extracellular matrix components, or cell adhesion molecules."
Seems to me like a promotional video of how well they are doing. Which is fine even if it's not true. But not fine if, "not true", holds up some other research which is.
trying to wait until they mention mitochandia....when????
Cell antenna
Want arabic translation please
Because they hav seen better ones..which are much more clear..
nice
Solution :
*Dr Otto Heinrich Warburg* German MD physiologist and biochemist, Nobel Prize for Physiology or Medicine in 1931:
*>*
Very good explanation
thank you
thank u