Olanzapine (Zyprexa): Everything you need to know!
ฝัง
- เผยแพร่เมื่อ 8 มิ.ย. 2024
- In this video, we discuss the top 7 things you need to know about olanzapine or Zyprexa. We discuss what olanzapine is, what it is used for, how long it takes to work, whether olanzapine is addicting, the side effects, drug interactions, and my final thoughts.
Intro 00:00
What is olanzapine (Zyprexa)- Mechanism of Action 01:00
What is olanzapinem (Zyprexa) used for? 02:09
How long does olanzapine take to work? 04:19
Is olanzapine addicting? 05:37
Side effects of olanzapine 06:31
Drug interactions related to olanzapine 11:47
My final thoughts and considerations of olanzapine 14:32
Resources:
Deprescribing Guide: amzn.to/4dZEUMk
Stahl's Prescribing Guide: amzn.to/3UXj8QL
🎥 This video was edited by:
Rahul Kanchi / rahulkanchi24
🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: blog.opencounseling.com/suici...
References:
Alsherbiny MA, Li CG. Medicinal Cannabis-Potential Drug Interactions. Medicines (Basel). 2018 Dec 23;6(1):3. doi: 10.3390/medicines6010003. PMID: 30583596; PMCID: PMC6473892.
FDA Label (2020). Retrieved from www-accessdata-fda-gov.libpro...
Uptodate (2022). Olanzapine: Drug Information. Retrieved from www-uptodate-com.libproxy.eku...
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
Patient Resource
medlineplus.gov/druginfo/meds...
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.
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accepted and will be taking olanzapine for my family attended lifestory and the family.s lasting love but if I take it before noon I don't have any communication issues if I take at evening it feels fatal I couldn't make out three words and felt like i.d have a stroke..why did he hear me out? 😢😢😢
apologies..*he hear me out
You like daily chemical lobotomies?
Do you prefer abilify over this medication?
Couldn't have asked for a better break down.
Thank you for making it so easy to comprehend
Glad it was helpful!
Thanks for your video. I just want to suggest that you mention another common side effect which is that this drug very often takes away the joy of life. It can turn you into a vegetable devoid of emotions. Im talking about a severe dulling down of the experience of life. I think you need to explain this in language like this that people understand. But thank you for your video it was very informative and i really appreciated the information.
Do you drink or use any mind altering drugs?
I'm from morocco and you are heelping people to understand what thy use and how they use it...and it's really nice from you thank you
Happy to hear that! Thanks for watching the videos!
Your brother hasan from Morocco just got put on olanzapine today I hope it work for me
@@elyousfi5661how you doing today
Hi! I love your informative and educational videos. Could you please make a video about quetiapine?
Great suggestion!
Thank you for your explanation this helped me understand this medication
Glad it was helpful!
Hi jezel roza.i love u and ur videos very much. Your videos are informative And Good.
Thank you!
聞き取りやすい英語。友達が服用している。私は全く知らない事なので参考になる。from Japan
Thank you doctor for sharing and explaining this mediaction
Excellent video
Thank you very much!
Love the transparency here. Thank you! I was recently forced to take this (as a shot because I got too stressed for too long, and I broke my mind) and it is really helping with my episodes.
Glad to hear you're on a treatment that works well for you.
Seriously, I hope things are much better now!! Same here, and I also have bipolar 2.
thank you for this video so much. I am taking olanzapine for more than a year, with pauses. My body has a good tolerance towards it, and it was prescribing to me as a med to enhance my nap.
"Nap".....? You mean as sleep medication ?
@@PAULLONDEN yes
This is the only thing that works for me to get some sleep and lower depression. Worth the early death chances.
could you please make a video on olanzapine combination treatment with sodium valproate and sertraline?
Why and how better fluoxetine olanzapine combination than another antidepressant combination with olanzapine? What is the specific point?
Hello doctor how are you today....thank you for your vidéos that you make it's really helpful to learn and help to chose the right drug that maybe good for me....recently i use sertaline and wellbutrin and vortioxetine in combinatien...i have a lack memory and focus because of m'y panic attack and anxiety suicidal thougs and i can't leave my bed is it good to combine this 3drugs or not i really need you answer if you can... Thank you so much
You will need to be careful to look for symptoms of serotonin syndrome, review this video th-cam.com/video/lhNXaG_kozE/w-d-xo.html
and the handout that is linked in the description so you know what to look for and also what other medications can put you at higher risk for this.
Thankyou ma'am for your information, I from India, a bipolar mental problems, under combination of divalproex sodium, olanzapine ,clonazepam . but yet sometimes I feel depressed or unwanted thoughts, like delusion or anger against someone , I have been living like this , Dr said I should be engaged minimum 6 hours by doing work, ofcourse I do regular walks and some workouts in the evening in park which relives my tension like depression, anger . please highlight another advice.
Cleaning up your diet may also help. Stay away from processed foods, sugars and simple carbs. Supplementing with an Omega 3 would also be beneficial. Definitely discuss with your doctor first to be sure no contraindications exist.
Interesting about Prozac with olanzapine
thank you for the video. Im taking a below therapeutic dose of half a 2,5 mg pill at night combined with 150 venlaflaxine. I hear voices when I'm going to sleep, so this should help according to my doctor.
I take 150mg of venlafaxine and 150mg of lyrica and I added 2.5mg of onzapine myself because I noticed positive changes. I have borderline disorder. I have a memory problem. You?
Has this helped
Has it helped you so far this combination?
Answer please 🙏
I'm on Methadone since 1973 ,these days 100 mg daily ,How will the interaction with Olanzapine be ?
Please do one on Vraylar/Reagila
Can you please make a video on ( if someone was taking zyprexia 5mg for major depressive disorder with psychotic features. Can they swap for Abilify 2mg) reason for swapping is find it makes me unmotivated and sedating. Please thanks you.
just got your video when i was trying to find bout my son , pls help me my son is 19 he faced psychosis when he was 15 his doctor started with risperidone & his situation is improved after 8 month he got free of medication but because of exam stress he faced 2nd psychosis and he was taking 20 mg Olanzapine & slowly reduced to 7.5mg his condition was ok . before 3 weeks the GP reduced to 5 mg and i can see some signs of being agitated and do you think he should back to 7.5 or he might be ok with 5mg when his body adjusted?
I take it for skitozoaffective disorder with Bipolar type
Thanks a lot
The side effects should scare a person well!
can you make a video about bipolar 2 ?
Thank you for the video! I am starting olanzapine today and was looking for more information on it and this video covers it all!
Glad it was helpful for you.
I’m scared to take it now because of all the side effects I’m not taking that
Keen to know how you are my sons been put on this yesterday
@@thelordisgood62 Most people are understandable somewhat hesitant to go on this kind of medication.
If you believe all the side effects you read about , you can't take even an aspirin . I had my doubts also , but started with half a 2,5 mg tablet , a few days later the other half. It had a positive effect.
Rather take the risk than being psychotic or depressed.
Can you please make a video on mirtazapine?
Can one/you withdrawal from Olanzapine/Zyprexa safely and successfully? Or do you relapse?
Doctor. I was wondering how can i get rid off emotional blunting caused by venlafaxine. I’ve stopped taking at a month ago. And i still suffer from emotional blunting.
Typically emotional bunting is a result of low dopamine. Bupropion may help with this, ask your doctor about it.
See a Chek practitioner
Plz make video on Marijuana addiction
Thank you for the video idea, I will consider it.
Olanzapine was the worst medication i took , palioeridone still didnt really afect me , no weight gain , its not bad but , someday when my problems are reolved i find peace and i will quit it to
@levelheaded mind make a video of olanzapine w/samidrophan please
Thanks for the video idea. I will consider this!
Thank yous
Thank you for all the information
Can you take lithium orotate with Zyprexa?
Yes you can, however discuss with your provider as dosage adjustments may need to be made along with lab tests.
@@LevelheadedMind Thank you
Summary
Commonly reported side effects of olanzapine include: asthenia, dizziness, drowsiness, extrapyramidal reaction, hyperkinetic muscle activity, akinesia, cogwheel rigidity, drug-induced parkinson's disease, dyspepsia, mask-like face, and xerostomia. Other side effects include: abnormal gait, back pain, constipation, fever, orthostatic hypotension, weight gain, myoclonus, and personality disorder. Continue reading for a comprehensive list of adverse effects.
But lets not mention this at all. WTF
Thanks for watching the video.
@@LevelheadedMind lmfao
yo the channels reply 💀
@@eve9990 it's insane.
Hey! The entire video was all about side effects.
I was taking this with Lexapro for PTSD worst crap! I was growing a whale… 3 years of hell…
does it has effect on white blood cell count
I was prescribed this with Lamictal for my depression resistance. I'm not bipolar or schizophrenic.
Is this a good combination?
I went through decades of being drugged with antidepressants including lamictal. None of then really stopped the depression. They disrupted my brain chemistry sobadly that after tapering it took me a few years to regain my regular feelings and personality. But what I did find worked was ating a 100% organic diet, having your own hugelkultur garden, surrounding myself with lovely pets and a loving supportive community, volunteer work and dailt exercise in nature. I still have bad days like every human does, but I am happier with this approach than I have been since the mid 1980's when the "doctors" thought that my childhood sexual assault by a Catholic cop who was my scout leader were "delusions" even though he was caught and fired for raping a child. Now with all the video footage of violent criminal cops, and the many thousands of court cases against the Catholic church and the 82,000 plaintiffs in the case against the scouts,we know he was the trifecta of pedophilia. But the doctors drugged me for that "delusion" for 4 decades. Doctors do not know everything...in fact they know incredibly little about life. Trust yourself and love yourself.Stay a way from drugs. Do research on how to create a healthy gut microbiome. Get chemicals out of your life and especially your food. Be courageous enough to allow yourself to shine and to truly be who YOU really are and who you want to be. Numbing and living a half life was not the answer and now at 60 I regret wasting somuch of my potential for somany years and listening to the "experts".
I don't think pluses will outweigh the downsides. In monkeys olanzapine reduces brain matter
Can I use olanzapine 5mg while am breastfeeding?
Hi! Is there any drug with a similar effect as onzapine? Its replacement or parallel. thanks
If you're concerned about weight gain or metabolic syndrome, you can try Lybalvi which is olanzapine with samidorphin.
Haloperidol
@@nenadcubric2663 sta je u pitanju?
Hello ,
My father is suffering from Schizophrenia from last 20 years and currently he is on Resperidon 3 mg , Olanzapine 10 mg , Trihexyphenidyl 5 mg , Tetrabenazin 25 mg . Currently fine with schizophrenia no positive and negative symptoms but facing EPS tremors , tardive dykenesia what can be done in this matter ma'am ?
Can Resperidon amd olanzapine tappered off ? Or 3 mg Resperidon and 10 mg Olanzapine minimum requirement for management of schizophrenia ?
Talk with his provider about this. Tapering down to lowest doses of medication can be helpful as long as it treats his symptoms. Furthermore, a VMAT inhibitor may be used to treat the TD side effects.
@@LevelheadedMind Thankyou so much for responding
@@suryaprakashpathak9611 i hope your father is ok now..is he feeling fatigue due to medication?
Is it good for lack of motivation I have this problem in my life and because of that I m lack of money
And I tried many ways to fix my self but I couldn't.
No, not good for lack of motivation.
Hi people iam from 🇬🇧 and have been taking this for 10 years now I put my self in to mental health hospital and the head scrink took me straight off with no reduction was similar to herion withdrawal and I know that first hand but trying to tell me there is no withdrawal from this what is going on here
Big pharma I guess.
idk. I find it hard to wake up in the morning if i have to work.
Perhaps my body will get used to it
I went from 127 to 159 on that med I like the weight gain
How long did it take?
This drug nearly ended my life for exactly the reasons you listed. This drug should be illegal. A health organic diet and exercise in nature combined with volunteer work and a loving supportive community is the answer. Not POISON!
Work for me no side effects 👍
would you be kind enough to share how long have you been taking it n on what dosage ? Have you felt any cognitive impairment whatsoever۔ ؟ wil b grateful for your reply۔ Regards
After taking Olanzapine, I can't speak fluently on both English and Filipino language. And I forgot some of sign languages learned in a year.
Hi. I'm a filipino who was prescribed with Olanzapine and I don't want to take it yet due to negative reactions with previous psychiatric medications. Am diagnosed with OCD. Why were you prescribed with Olanzapine?
Same here after taking this medicine I can't speak fluently and I keep stammering. My mouth opening has also been very small. I want to get rid of all these bipolar disorder medications...
Olanzapine reduces brain in monkeys. Psychiatrists like to say it's schizophrenia and depression which cause brain damage but some believe it's antipsychotics
@@greenmachine_kevivhi, how many mg are you taking ?
I've had a stomach condition hiatal hernia that prevented me from gaining weight. They diagnosed me with anorexia which ok fine, but I didn't get here because I'm afraid to gain weight. So they're putting me on this to gain weight....which is all good and well but is it really worth the abundance of side effects?
Probably not my guy, doctors need to weigh the pros and cons of the drug and I'm no doctor but i think that to use it just for weight gain it's overkill. Unless its also to help you mentally, like if you have intrusive thoughts that prevent you from eating. Discuss with your doctor an alternative option or at least an exit strategy such as when you hit a goal weight you can come off of it
@@brokensocrates827 Hey thanks, I really appreciate your insight. Yah it's tough road ahead, I feel like this would just mask the issue but I am gonna start on only 2.5 so we'll see how it goes. I'd rather try and take digestive enzymes to help break down the protein cause that's what I'm really struggling with.
Please speak with your doctor about your concerns. There are safer medications to help with weight gain and even natural remedies.
I started these three days ago and since I have felt human and feel so much more happier 😅bout time I was getting tired of being tired with quetiapine 😅😅 40 yrs old this year but think I have the tablet for me, just not sure why this is working for me still no “label” with it 🙄🤷♀️🙌
What dose? At night or in morning?
@@andreasaasen5950 2.5 take morning, noon and night most avhad is 10mg but was told can go up to 20 within a couple months before I see my psychiatrist again, hope this helps
how can i stop taking olanzapine safely , plzz help
Talk with your provider about a slow taper or cross taper if you plan to switch to a different medication.
Yes thanks doctors and nurses for making me fat. I can no longer play sport or exercise properly so thx for that. Thx olanzapine for ruining my life for me. How can you sleep at night doctors and nurses.
yes gained 10kgs mostly around my mid section no comfy at all
Zyprexa saved my life about 10 years ago. It's the only thing that works on my anxiety.
wd you b kind enough to share how long n what dosage are you taking n r u having any side affects ؟
Great video not bad, I've been on zyprea 5 mg. for over 6 years I'm fully aware of possible weight gain & other side effects most of it doesn't bother me haven't had a manic episode since august 2020 along with epilim sodium valproate I feel much better these days they both work wonderfully 👍👍😉😉
Glad you found something that works well for you.
No negative symptoms?
@@chanderkantacharya9918 not from what I've noticed during that time but recently I did suffer a few minor episodes
I've been taking olanzepine for about 3 months and lithium for 2 months and have gained 20 pounds. Other than that, I'm doing ok on these meds. Much better than I was without them and was in mania! Thank you for this video.
would you be kind enough to share what dosage you are on and if you have felt any cognitive impairment or memory related issues ۔؟ n if so how you manage them ؟
my mom uses this
Have you seen The Zyprexa Papers? It may be a very, very bad medication.
It is. It's garbage. All they are doing is giving you a chemical lobotomy. Murdering your frontal lobe. The front part of your brain.
"May be"? No; it IS a very, very bad medication.
more meds more money
for doctors and Pharma companies
Now in my city people are getting awareness about These drugs
I hope soon psychiatry will abolished
I'm on this medication 💊 it makes me sleepy is that Normal
Yes, that is a common side effect, so that is why you take it at night.
I take it....
Sleeping for around 12 hours is normal.
No momentum and drunk feeling is also normal.
Careful about weight gain, My advice is to always have your belly full with tea and the like to kill the hunger pain.
Best of luck
I also sleep 12 hours. Some people say they sleep 14-16 hours
@@Tomsthumb wd you b kind enough to share how long have you been taking it۔۔what dosage n if you have had any issues related to memory ? Wil b grateful۔ Regards
@@HJS17 20mg Ive took for around 20 years.
Straight up tell you google researching is false and confirmed lies.
As a musician thats put my 20k hours in I dare you to sing on it.
As a musician I need to remember notes.... that too is difficult.
Can i take zebrexa with seroquel
*On Telegrams and Instagram as*
*@Chequefibs1__*
olanzapine is causing constipation.. what to do?
Discuss this with your provider, there are many things you can do. Increase your water and fiber intake, use a stool softener or laxative, if approved by your MD, use probiotics, etc.
i take psyllium husk supplement in the morning. it really really helps.
Get off the drug sagely now before it ruins your life like it did me and many others!!!
then what should i do?
@@jamiepackwood1896 I've had a stomach condition hiatal hernia that prevented me from gaining weight. They diagnosed me with anorexia which ok fine, but I didn't get here because I'm afraid to gain weight. So they're putting me on this to gain weight....which is all good and well but is it really worth the abundance of side effects?
Why does it sound like this is some hip hop reaction video?
no problem with risperidone i had shingles that are gone now and risperidone did nt affect me sexually in a negative way 100% positive im going to ask my doctor to prescribe Olanzapine to me
😮
Is zyprexa a benzo?
No, Zyprexa is not a benzo.
Thank u so much for answering that question for me
Theinobenzodiazapine, hits many of the same receptors as benzos do, very dangerous medication!!!!!
@@LevelheadedMind thank you
@@LevelheadedMind I have been on a low dose of 2.5mg for 6 months. But tried to come off it twice and panicked when I couldn't sleep as I have to work. Also gained weight. Any advise? My psych said I can come off it.
My psychiatrist describe it to me with Sertraline
Notice how non of these people can tell you how it works.
Truth is, it will f uck your world up.😊
This video is more than misleading first of all Olanzapines main indication is schizophrenia it is approved for the things you said but naming those first is misleading by making people with bipolar more comfortable taking these medications constantly I have also not heard of anyone with bipolar getting a long lasting injectable that is called Schizoaffective and is a different disorder that is if you have bipolar and psychotic features then by explaining the receptor thing it is correct but we know very little about those receptors and here Olanzapine is considered a high potency antipsychotic that can replace benperidol in writing (article about benperidol talking about reasons why it’s gone out of favor) Which is stronger than haloperidol (Haldol Janssen) which is overkill for adding as a depression treatment with fluoexetine also you are just meantioning fluoexetine (prozac) while in most literature any antidepressant is named there used to be a combination product called symbiax which had both of them another attempt of Eli Lilly to extend Prozacs patent do you maybe have any conflicts of interest to declare? You declare your a nurse anyways also an injection will do the exact same thing as the pill just that the pill takes a bit longer about an hour to maybe 3 hours for peak plasma I have to look up again your talking about how long it takes for a schizophrenic patient that responds needs to fully recover of all symptoms for mania a pill will be just as effective and the orally dispersable version you mentioned also works faster and controls agitation and aggression, mania and even psychotic symptoms from the first pill even the pill does
Thanks for your insight. Guess you haven't spent much time on the channel to understand that I am first and foremost an advocate of using skills before pills. I make this videos to provide a form of informed consent so that patients can understand what they are taking, since most providers don't have the time to explain. And most patients dont read the meducation labels. I get most of the information from the FDA label.
@@LevelheadedMind I guess I didn’t spend enough time on your channel. I agree and am thinking about starting a project of my own for harm reduction in substance abuse. (A lot of the existing channels are very biased and ignore studies that f.e MDMA is neurotoxic and make bogus claims that so and so many times a year is fine. It is neurotoxic every time our brain is just great at adapting to lower levels of serotonin until it is too late). And education about psychiatric drugs maybe a second channel because a lot of substances are misunderstood used wrong by doctors and have a stigma like haldol. I know someone that’s on the LAI that tried like a lot of atypicals was on abilify and loxapine and still had hallucinations. Since he’s been on haldol he’s been able to live somewhat of a normal life as far as I can tell still there is a lot of people receiving medications that are overkill and we have great treatments now like: Latuda,Vraylar(seems to be 50/50 for most of the people I talk to either don’t like it or best med they ever tried) and we’ll see how Caplyta will fair I think it’s interesting structurally (it being related to low potency buyrophenones like pipamperone). Invega seems to be great for a lot of people and Zyprexa seems to be one of the most effective APs period. With actual statistical difference and superiority in the CATIE study (effectiveness 10% over control perphenazine. Risperidone was about as effective as pphz everything else faired less it’s an older study and none of the meds I just mentioned were included. And I also know people that are stable on a lot of the meds that were less effective then perphenazine. I think the most important thing is that people can try a lot of different medication because I’ve seen meds work for people where you wouldn’t have expected sometimes. And there is some evidence that hasn’t been investigated since the 90s that certain low potency first gens like levomepromazine are not only atypical but also effective in treatment resistant schizophrenia. And Trimipramine has almost the identical binding profile to most D and 5ht receptors as clozapine. And was also deemed effective in a study for treatment resistant schizophrenia as well. The advent of atypicals the studies were around 91/92 and the availability of so many different ones shelved these things still very interesting and potential options for non-responders! If you want I’ll try to find you the studies. Anyways thanks for the reply keep educating people!
OLANZapine is horrific
Olanzapine save my wife,my family.pls dont take your sickness for geanted guys.pls follow your doctor prescription.the side effects will be gone in few weeks time.
wd you b kind enough to share how long have you been taking it۔۔what dosage n if you have had any issues related to memory ? Wil b grateful۔ Regards
You cant say this drug isnt addictive then use withdrawls in the same sentence. Just bc you dont crave it like you would a street drug doesnt mean its not addictive.
you’re mixing up “addiction” and “dependence”. just because someone experiences withdrawal does not mean they were addicted.
There is a difference between addiction and dependence caused by neuroadaptation which I discuss in this video th-cam.com/video/LvlibMbSOo4/w-d-xo.html
@@incessantmurkysmuggler if you are addicted to something. You are dependent on it. If you are dependent on something thats an addiction
Even if there is a difference being dependent on a drug is not good especially if it hurts you when you dont have it
@@LevelheadedMindyou are a cash grabbing hypocrite
Duc poyde ba maka anak yan na gagot
Don't be listening to you tube people's comments just take your medication as your doctor prescribed you'll be ok 👌
THANK YOU 🙏
Whatever. I watched this medicine destroy my daughter's life in 8 months.....
@@jackmewhalle6937 it worked for me. It’s not a drug for everyone. may I ask what happened?
@@jackmewhalle6937what happened? And what dosage your daughter was taking?
@@user-cw5pe3jr9g I don't know the dose that she was taking..... She's 5 ft 5 and she weighed 130. Within 8 months she weighed 171. I first started noticing that she was getting dramatic about everything she spoke about... And then she started getting delusional and thought that she was hearing demons and seeing demons in her house. Within 8 months she had went from being the most stable logical female I'd ever met. To be an irrational to the point that she lost a relationship and also lost her job..... She is now off the medicine and she's starting to come back to the person she used to be. She's down to 145 lds... Doing no exercise whatsoever.... Also she hardly ever drink alcohol she had probably drink alcohol 30 times in their entire life and she's 33 years old. She was up to drinking three bottles of vodka straight every week. Now she is down to drinking a couple of glasses of wine a night..... So this medicine might be good for some people but definitely was not good for my daughter.
a terrible substance, should be banned in germany as well..