trp Operon & Attenuation explained in under 15 minutes

As one of the classic examples of gene regulation the trp-operon in E. coli is the prime model for transcription attenuation regulating tryptophan synthesis.
To synthesize Tryptophan this operon is regulated by two distinct mechanisms, firstly a tryptophan repressor and secondly transcription attenuation.
In this video you will learn how the DNA binding affinity of the tryptophan repressor will regulation the trp operon and how transcription attenuation is able to form exclusive secondary structures to regulate the trp operon as a second layer of regulation
How is it done? Just find it out in under 15 minutes.
This is MiBIOs lecture video series about the fantastic world of microbiology.

[@dauren.00]

this guy deserves his name been written with golden words

[@celiza9]

This was such an incredible explanation--thank you!

[@casiopea3399]

Great animations, very well explained! Thank you for the video.

[@satabdideka31]

Thanks a lot, great explanation!

[@StaleyBrittany]

This helped SO much! Thank you!!

[@minnumariya4612]

Amazing explanation! Thank you

[@user-mr1jc1tn1x]

Thank you that was a fantastic help for my understanding!

[@karishmasultana2450]

This was really helpful! Thank You 😁

[@an-sofievandeputte7188]

Very helpful! Thank you

[@anoshfernando55]

Amazing explanation. Thank you so much!

[@nikolaizakrewsky4406]

So helpful! Thank you so much!

[@samantharodriguez337]

Very very helpful. Thank you so much.

[@annaschmieding]

Thank you for this video!!

[@lovemoredaka4942]

Thank you for the nice explaination

[@emmahughes1346]

So helpful thank you!

[@biochemksmu]

Great explanation

[@user-dq2fd2wo9g]

great lecture

[@SagarSharma-up9zw]

very good explanation sir

[@mohammadhosseinheidari4173]

That was great! thank you

[@maheensaeed7889]

THANK YOU!!

[@manavnaik5358]

Thanks mate!

[@wasteddemise2286]

Bless your heart❤

[@AvnishRaghuvanshi]

How translation continued in low trp while there is a stem loop in its path?

[@biochemksmu]

But IMHO there is a little bit another mechanism of translation continuing in the low trp situation. New ribosome is attached to the starting AUG codone of trp-E enzymes mRNA

[@Gravyy06]

🐐

[@melindareyes8393]

how does the RNA polymerase continue to transcribe the leader sequence if tryptophan is high? the repressor will bind to the operator if tryptophan is high (corepressor) and so the RNA pol is blocked.

[@oyletaklyozfln1763]

Well im wondering same thing I MEAN HOW but after this vid im thinking maybe tRNA holding trp and thats why repressor not working ???

[@momhrm247]

👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍

[@sutejbains96]

Why did he stop making videos ??

[@priscarogi2183]

start at 4:30 for attenuation