DNA, Hot Pockets, & The Longest Word Ever: Crash Course Biology #11

แชร์
ฝัง
  • เผยแพร่เมื่อ 8 เม.ย. 2012
  • Hank imagines himself breaking into the Hot Pockets factory to steal their secret recipes and instruction manuals in order to help us understand how the processes known as DNA transcription and translation allow our cells to build proteins.
    Table of Contents:
    1) Transcription 2:12
    A) Transcription Unit 3:00
    B) Promoter 3:10
    C) TATA Box 3:32
    D) RNA Polymerase 4:12
    E) mRNA 4:15
    F) Termination signal 5:21
    G) 5' Cap & Poly-A Tail 5:34
    2) RNA Splicing 6:08
    A) SNuRPs & Spliceosome 6:26
    B) Exons & Introns 6:56
    3) Translation 7:28
    A) mRNA & tRNA 8:01
    B) Triplet Codons & Anticodons 8:39
    4) Folding & Protein Structure 10:51
    A) Primary Structure 11:11
    B) Secondary Structure 11:23
    C) Tertiary Structure 11:58
    D) Quaternary Structure 12:44
    Links to episodes referenced in the video:
    DNA structure episode: • DNA Structure and Repl...
    Animal cells episode: • Eukaryopolis - The Cit...
    Fold-it SciShow episode: • Foldit Gamers FTW
    This video contains the following sounds from Freesound.org:
    "IMPresora.wav" by melack
    "swishes.wav" by pogotron
    Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
    Want to find Crash Course elsewhere on the internet?
    Facebook - / youtubecrashcourse
    Twitter - / thecrashcourse
    Instagram - / thecrashcourse
    CC Kids: / crashcoursekids

ความคิดเห็น • 3.5K

  • @marianhenderson1759
    @marianhenderson1759 4 ปีที่แล้ว +2666

    My biology exam: "Describe the processes of transcription and translation"
    Me: So hOtPoCkEtS...

  • @lintafatima2253
    @lintafatima2253 4 ปีที่แล้ว +1969

    all the comments from 5 years ago then there's me in 2020 tryna study this for my final tmrw

  • @colossaltitan3546
    @colossaltitan3546 4 ปีที่แล้ว +1354

    "Hey what's your WiFi password?"
    "It's on the back of the router."
    *Back of the router: **0:01*

  • @Jeanjellybean13
    @Jeanjellybean13 8 ปีที่แล้ว +6866

    God bless the editor who had to type that word for the video

    • @DevinSporteh1681
      @DevinSporteh1681 8 ปีที่แล้ว +697

      +Jeannie Weasly Or, copied and pasted it from a website. :)

    • @Jeanjellybean13
      @Jeanjellybean13 8 ปีที่แล้ว +308

      true, still that would be long copy and paste

    • @lalaithan
      @lalaithan 8 ปีที่แล้ว +174

      +Jeannie Weasly It would take less than a second to copy and paste.

    • @dipperpines6587
      @dipperpines6587 8 ปีที่แล้ว +671

      +lalaithan What about the guy who had to put it on the website in the first place? Poor chap.

    • @lalaithan
      @lalaithan 8 ปีที่แล้ว +86

      +Dipper Pines Just a wild guess, but that person probably enjoys DNA-related topics or spreading knowledge and probably isn't bothered by typing.

  • @Unanimious
    @Unanimious 9 ปีที่แล้ว +6368

    Has anyone ever thought about this? This guy teaches in 14 minutes what a teacher takes 2 weeks to explain...

    • @nicolecoolkid1
      @nicolecoolkid1 9 ปีที่แล้ว +425

      yeah but you kind of need a teacher to tell you this BEFORE watching crashcourse

    • @DanFoxDavies
      @DanFoxDavies 9 ปีที่แล้ว +252

      Catia Park
      It's all about how the brain takes in information. The majority of people need a slower, more in-depth explanation first, followed by quick reminders like this, if we assume that the current educational system is broadly on the right track, that is. If you just watched these without prior subject knowledge and then went for a test at A-level or degree level, you might not remember it all. However, if you have an unusual brain that is able to memorise every syllable of information crystal-clear, go for it.

    • @s.a.1615
      @s.a.1615 9 ปีที่แล้ว +20

      ... Well I can't do that, I usually just do some research and write about it n I'm fine 2 go 😜 (I'm not sure how long I'll remember it tho, depends on how interesting I find it!

    • @ibrahimomoyayi9325
      @ibrahimomoyayi9325 9 ปีที่แล้ว +4

      ıts amazıng

    • @jm56481
      @jm56481 9 ปีที่แล้ว +95

      my professor actually went through it as quickly as this guy except he didnt explain anything

  • @timothywarner8292
    @timothywarner8292 7 ปีที่แล้ว +3044

    the protein at the bottom of the screen gives me anxiety.

    • @nicolevergara9958
      @nicolevergara9958 7 ปีที่แล้ว +11

      Tim Warner omg I'm not alone

    • @karrarhussein355
      @karrarhussein355 7 ปีที่แล้ว +12

      Allah Akbar..
      be careful or it will bomb on your face

    • @stephendonovan9084
      @stephendonovan9084 7 ปีที่แล้ว +72

      How ironic that the fear of long words would itself trigger a fear of long words.
      I have hippopotomonstroOOOOOOOOOOOOOOAAAAAAAAAAAAAAAAAAAAAAAHOHGODWHY

    • @aviona123
      @aviona123 6 ปีที่แล้ว +9

      I WAS JUST ABOUT TO SAY THIS ,LIKE WHO WAS RESPONSIBLE FOR ALL THAT JFC

    • @mochastudies8514
      @mochastudies8514 6 ปีที่แล้ว

      YES

  • @temporaryname4620
    @temporaryname4620 4 ปีที่แล้ว +1038

    On a test:
    Question 14: What is the other name for Titin?

  • @BryanSarauer
    @BryanSarauer 8 ปีที่แล้ว +2703

    Hank talks pretty fast. So, I decided to play it at 0.5 speed to see how that goes. What resulted was the awesome discovery that Hank sounds totally hammered at half speed. Try it, you won't be disappointed.

    • @meinkanta
      @meinkanta 8 ปีที่แล้ว +42

      I can't do this on my phone, but I can imagine it! Oh lord

    • @danieldavis3675
      @danieldavis3675 8 ปีที่แล้ว +68

      +Bryan Sarauer i had to do it, Best. Thing. Ever. LOL

    • @pEAcEgrL81596
      @pEAcEgrL81596 8 ปีที่แล้ว +9

      +Bryan Sarauer hahahahaha

    • @StAndAl0neCompl3x
      @StAndAl0neCompl3x 8 ปีที่แล้ว +6

      +Bryan Sarauer LMAO

    • @asolomone
      @asolomone 8 ปีที่แล้ว +81

      first 17 seconds in 0.5 made me burst out laughing thank you for that amazing discovery

  • @swordyuri
    @swordyuri 8 ปีที่แล้ว +1951

    And that was 2 weeks of school in 14 minutes.
    Boy, I do love crash course.

    • @ishaikaru6311
      @ishaikaru6311 6 ปีที่แล้ว +5

      crash course rulessssssssssssssssssssssssssssssss!

    • @matty7834
      @matty7834 6 ปีที่แล้ว +11

      Sandhya Ganesan 2 weeks!?! We did that in one lesson, where do you live?

    • @matty7834
      @matty7834 6 ปีที่แล้ว +1

      Sandhya Ganesan how old are you?

    • @swordyuri
      @swordyuri 6 ปีที่แล้ว +13

      well, we did it in one lesson this week, but i made that comment two years ago so it took much longer then, as opposed to my current bio honors class

    • @wakajacka557
      @wakajacka557 6 ปีที่แล้ว +3

      Yeah, one lesson for me too. came back to this video so I can understand it better and I think I'm finally getting it after 5 attempts xD

  • @memr1a
    @memr1a 4 ปีที่แล้ว +319

    Imagine how chaotically beautiful medicine would be if everyone had the naming sense of the dude who named Snurps and Spliceosome

  • @VikingArhold
    @VikingArhold 8 ปีที่แล้ว +3907

    poor scientist who had to write down the name of titin

    • @haydog.b8880
      @haydog.b8880 8 ปีที่แล้ว +15

      +Viking Arhold wouldn't they have chosen to make it that long

    • @philipmalan4967
      @philipmalan4967 8 ปีที่แล้ว +51

      Don't worry, he just used a random number generator to make it ;)

    • @rajatkamalpolisety2864
      @rajatkamalpolisety2864 8 ปีที่แล้ว +92

      +gameturbo131 don't you mean random letter generator? lol ;)

    • @philipmalan4967
      @philipmalan4967 8 ปีที่แล้ว +11

      Fadel That makes sense XD why else would you have a pointlessly long name?

    • @rajatkamalpolisety2864
      @rajatkamalpolisety2864 8 ปีที่แล้ว +14

      yeah +gameturbo131 lol unless you are talking about supercalifragilisticexpialidocious

  • @SkyVyrNox
    @SkyVyrNox 4 ปีที่แล้ว +237

    Nobody:
    Poly-A tails be like: *_AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA_*
    Yes, there are 250 of them

  • @hasini
    @hasini 10 ปีที่แล้ว +476

    whoever took the time to write down that protein at the bottom of the screen - I commend you for the time and effort you put into that

    • @altie29
      @altie29 10 ปีที่แล้ว +45

      unless they just copy/pasted...

    • @HendrikHenderson
      @HendrikHenderson 10 ปีที่แล้ว +78

      altie29 Someone had to write it down first; the original person who bothered to write down Titin on the internet.

    • @mikotorubychan
      @mikotorubychan 10 ปีที่แล้ว +10

      Hendrik Henderson Who the hell named it really -__-

    • @HendrikHenderson
      @HendrikHenderson 10 ปีที่แล้ว +33

      mikotorubychan It's incredibly long name is actually not a result of a bored scientist; Titin happens to be an IMMENSELY long protein strand, and there is a certain scientific formula for naming proteins. Most proteins have long names, but Titin's unusual length makes it have a longer name than usual.

    • @sabrinaguibord407
      @sabrinaguibord407 10 ปีที่แล้ว +1

      I think they copied and pasted

  • @roobie5901
    @roobie5901 ปีที่แล้ว +142

    me, a senior in a biomedical degree, needed some hank green to resimplify transcription and translation after my professor made it unbelievably complicated. thanks hank for making me feel sane

  • @devankhodiyar8366
    @devankhodiyar8366 ปีที่แล้ว +130

    Table of Contents:
    1) Transcription 2:12
    A) Transcription Unit 3:00
    B) Promoter 3:10
    C) TATA Box 3:32
    D) RNA Polymerase 4:12
    E) mRNA 4:15
    F) Termination signal 5:21
    G) 5' Cap & Poly-A Tail 5:34
    2) RNA Splicing 6:08
    A) SNuRPs & Spliceosome 6:26
    B) Exons & Introns 6:56
    3) Translation 7:28
    A) mRNA & tRNA 8:01
    B) Triplet Codons & Anticodons 8:39
    4) Folding & Protein Structure 10:51
    A) Primary Structure 11:11
    B) Secondary Structure 11:23
    C) Tertiary Structure 11:58
    D) Quaternary Structure 12:44

  • @thecoIorviolet
    @thecoIorviolet 5 ปีที่แล้ว +380

    Im convinced the editor just wrote random letters after the first 10 seconds

  • @abowman2580
    @abowman2580 5 ปีที่แล้ว +256

    "sorry for all the terminology"
    NO! For gods sake man, I have a midterm in two days. More terminology. Save us Obi-Hank, you're our only hope

  • @mickeynotmouse
    @mickeynotmouse 8 ปีที่แล้ว +855

    guys
    This entire thing is INSANE
    Don't you guys think this shit is MIND BLOWING? this shit is happening in EVERY SINGLE ONE OF YOUR CELLS
    How do they? Who.. Who told them to do this? WHy do they do this?? WHAT

    • @laritin4605
      @laritin4605 8 ปีที่แล้ว +52

      +mickeynotmouse JESUS

    • @second_second_
      @second_second_ 8 ปีที่แล้ว +59

      +mickeynotmouse God

    • @airro3672
      @airro3672 8 ปีที่แล้ว +5

      Brain

    • @mickeynotmouse
      @mickeynotmouse 8 ปีที่แล้ว +86

      the brain is just made up of MORE CELLS DUDE WHAT DO YOU MEAN BRAIN

    • @KuraSourTakanHour
      @KuraSourTakanHour 8 ปีที่แล้ว +38

      +mickeynotmouse They move and assemble via the random movement of tiny particles on their size-scale (because they're so small they're moved about by the tiniest force, absolutely everywhere, very fast and jittery) and behave according to a force of entropy (a natural force, like gravity), using up the free energy around them until they form a stable molecule. Because of the shape of some molecules, like the base pairs and amino acids, they'll only arrange in certain ways with the opposite molecule that fits them, or into an optimal (best) position/energy state. Some physics comes into the biology of understanding how the particles behave... but as to how they became this way, the most well-reasoned explaination is evolution and mutation.
      At the beginning of life, the theory (short version) is that chemical particles reacted to form amino acids which formed proteins that lead to the first RNA, but the evolution of cells and and how they developed these complex processes needs... a bit of a stretch of imagination.

  • @msjonyba1234
    @msjonyba1234 8 ปีที่แล้ว +36

    "All of those hydrogen bonds cause wrinkled sheets. UHUH!"
    XD Hank, that had me weak! 10/10.

  • @mariahpaige1
    @mariahpaige1 8 ปีที่แล้ว +1902

    who else has a final tomorrow and didn't study?

  • @yasmineabdouni3042
    @yasmineabdouni3042 8 ปีที่แล้ว +477

    God bless this guy. I don't think I'd be passing honors bio with out him 🙏🏼

    • @louistournas120
      @louistournas120 8 ปีที่แล้ว +2

      He was blessed by the lord FSM.

    • @violetquartz8817
      @violetquartz8817 8 ปีที่แล้ว +5

      +yasmine abdouni SAME I'D FAIL HARDER THAN I ALREADY DO

    • @larahorhor5470
      @larahorhor5470 8 ปีที่แล้ว +1

      +yasmine abdouni i still am not... lol hopless

    • @diozavgemd2521
      @diozavgemd2521 8 ปีที่แล้ว +8

      +yasmine abdouni Using him for some last minute ap bio, for a bit of basic review.

  • @hedgeearthridge6807
    @hedgeearthridge6807 5 ปีที่แล้ว +102

    "What are you going to name the Splice thing, professor?"
    "The... Ummm.... Uhhhh.... Splice... osome? Spliceosome???? I guess???"

    • @pinkcowjl
      @pinkcowjl 4 ปีที่แล้ว +8

      Okay but snurps though 😂 finally a science word I can remember!!!

  • @rohansawhney8203
    @rohansawhney8203 8 ปีที่แล้ว +360

    How do u eat DNA spaghetti ????
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    With a replication fork

  • @BellaBaris
    @BellaBaris 7 ปีที่แล้ว +271

    Crash course makes A level biology much more understandable and fun!

  • @khalilbuchanan6767
    @khalilbuchanan6767 10 ปีที่แล้ว +184

    Exactly, in 14 Minutes he's done more than I've learned in 14 days...

    • @greenerdays999
      @greenerdays999 10 ปีที่แล้ว +5

      Well you have to go home and study on your own. Your teacher can't hammer it into your head in 1 hour this stuff is complicated.

    • @DaKingOfBall23
      @DaKingOfBall23 10 ปีที่แล้ว +1

      boost

    • @andyyoung7657
      @andyyoung7657 10 ปีที่แล้ว +3

      newyorks516 well hank lightly tapped it all in our heads in just over 14 minuets.

    • @greenerdays999
      @greenerdays999 10 ปีที่แล้ว

      This video should serve as no more than a review or reinforcement to material you have already studied and learned on your own, from a textbook. Unless you are not majoring in biology or any of the sciences ( and you think this will suffice for exams) I recommend you do more than watch a 14 minute video on such complex concepts.

    • @andyyoung7657
      @andyyoung7657 10 ปีที่แล้ว

      newyorks516 dude I'm a freshmen in high school, plus I want to go into psychology.

  • @W3AFed
    @W3AFed 8 ปีที่แล้ว +247

    Hank Green is saving my Biology A Level one video at a time.

    • @honestleen
      @honestleen 7 ปีที่แล้ว +18

      if this aint me then idk what is

    • @RA-ex7ir
      @RA-ex7ir 6 ปีที่แล้ว +1

      can i say how true this is

  • @betlong101
    @betlong101 8 ปีที่แล้ว +182

    I saw a typo in the full word for titin. I demand for it to be fixed.

    • @gezzapk
      @gezzapk 5 ปีที่แล้ว +10

      Fire the editor!

  • @captainlightbulb
    @captainlightbulb 7 ปีที่แล้ว +369

    I will find that word and dedicate my life to memorizing it

    • @abdulbelfakih8776
      @abdulbelfakih8776 7 ปีที่แล้ว +10

      Captain Lightbulb why

    • @Morphiuss
      @Morphiuss 7 ปีที่แล้ว +58

      because he is captain lightbulb

    • @MultiKnightHunter
      @MultiKnightHunter 7 ปีที่แล้ว +1

      Basil Almasri dont act cute

    • @imogenasenath9669
      @imogenasenath9669 7 ปีที่แล้ว +3

      xStussGeo don't tell them what to do >:[

    • @livonneptune7347
      @livonneptune7347 7 ปีที่แล้ว +53

      It's been three months, memorize it yet?

  • @CartoonDrama44
    @CartoonDrama44 9 ปีที่แล้ว +56

    Have you ever wondered why the DNA contains thymine, while the RNA contains uracil? Here's an interesting fact. A spontaneous process called deamination (replacement of amino fuctional groups with keto groups) is fairly common in both DNA and RNA. As it happens, the product of deamination of cytosine is uracyl, and it is the most common of deamination processes affecting the DNA. The product of cytosine deamination (uracil) is readily recognized as foreign in DNA and is removed by a repair system. If DNA normally contained uracil, recognition of uracils resulting from deamination of cytosine would be more difficult and that would in the long run lead to a decrease in GC base pairs and an increase in AU base pairs in the DNA of all cells. Establishing thymine as one of the four bases in DNA may have been one of the crucial turning points in evolution, making the long-term storage of genetic information possible. (Source: Lehninger Principles of Biochemistry)
    Also, we commonly speak about introns as the junk which gets spliced leaving the ''important'' stuff for translation. Why do organisms have introns at all? It has been shown that introns are responsible for boosting expression levels of proteins up to 400(!) times (parts of DNA coding for introns include regulatory elements involved in transcription), they contribute to DNA packaging (chromatin formation), control the delay between gene activation and appearence of its protein product (which is especially important in developmental processes) and are responsible for alternative splicing. This latter process is extremely important because it allows one gene to produce multiple proteins, thereby increasing complexity of organisms without the need for occurrence of thousands of new genes. Also, many non-coding RNAs are actually products of spliced introns, such as miRNA, snoRNA, lncRNA, siRNA... (Source: www.ncbi.nlm.nih.gov/pmc/articles/PMC3325483/)

  • @dieman482
    @dieman482 10 ปีที่แล้ว +122

    there honestly needs to be teachers like you because teachers who cant teach but are there cause that the only job they can have need to stop.......

    • @zxdc1230
      @zxdc1230 10 ปีที่แล้ว +11

      my bio teacher lol

    • @mypuppy4U
      @mypuppy4U 10 ปีที่แล้ว +1

      Raul Pinto or anthropology teacher!

  • @stevenboxleitner4612
    @stevenboxleitner4612 4 ปีที่แล้ว +68

    I'm studying for the AP Bio 2020 test on Monday the 18th, so the Crash Course intro is now my personal theme song XD
    Also, for anyone studying (or cramming) for the AP Exam:
    Things are different. Things are /hard/. We've struggled all year, clawing and biting our way through the piles and piles of knowledge that class has thrown at us. But this just proves how freakin' STRONG we are! Look at all we've come through! For what feels like forever, we sleep, eat, and breathe SCIENCE. And it's gonna pay off. I promise. WE CAN DO THIS!!!!!!!!!! On Monday, we're gonna put on our comfiest clothes, grab some coffee/tea, log onto that computer, and show this world just how awesome we are!!! You might be feeling a little powerless in the face of new changes - or even in the face of the all-too-familiar enemy of self-doubt. But once you realize that there's no punishment for failure and only reward for success - that's power. Once you realize how /prepared/ and /intelligent/ you are just for making it this far already, /that's/ power. You've got this. Trust yourself to do amazing on this, and I promise you, you'll come out on top.

    • @red-pe1ue
      @red-pe1ue 4 ปีที่แล้ว +1

      my friend, the time has come, let's all pass this test!

    • @stevenboxleitner4612
      @stevenboxleitner4612 4 ปีที่แล้ว

      @@red-pe1ue YES!!! Good luck and keep that positivity going strong! :)

  • @HunterCivilianPlays
    @HunterCivilianPlays 8 ปีที่แล้ว +183

    When he writes with the marker on the glass, he write backwards, doesn't he?
    drah eb tsum tahT

    • @TheMkhan2
      @TheMkhan2 4 ปีที่แล้ว +12

      drawof setirw eh ,aremac eht pilf yehT

    • @Zer0_Flowers
      @Zer0_Flowers 4 ปีที่แล้ว +9

      HunterCivilianPlays nah I can both write and read backwards
      nuf rof ti od i

    • @notunique0000
      @notunique0000 4 ปีที่แล้ว

      Speroking the Untitled +1

  • @Ciize09
    @Ciize09 8 ปีที่แล้ว +91

    Just wanted to point out two minor "mistakes" in the video at the 9 minute mark.
    1. The first tRNA should be in the middle side of the ribosome ("site P"), THEN the second tRNA will go in the right side ("site A")
    2. The ribosome should be the one "moving" during the animation, not the mRNA
    Anyway, awesome 14 min explanation!

    • @__-ld9pt
      @__-ld9pt 8 ปีที่แล้ว +1

      +Ciize09 thank you
      highered.mheducation.com/sites/0072943696/student_view0/chapter3/animation__how_translation_works.html

  • @augustus6285
    @augustus6285 7 ปีที่แล้ว +57

    These videos are a part of my homeschool biology curriculum. Great work Hank!
    Also ham and cheese Hot Pockets are my favorite as well.

  • @foreverfaeriejoy
    @foreverfaeriejoy 7 ปีที่แล้ว +99

    "YOU NEED TO KNOW IT" lol died laughing

  • @Abominatrix650
    @Abominatrix650 8 ปีที่แล้ว +251

    Today I had a lecture by a lecturer who studies proteins. When he asked us to give examples of proteins, I gave Titin as an example. He was like "OK...that's a protein, apparently."
    Longest protein in the world and he doesn't know about it, despite studying proteins...what?

    • @ratatat12356
      @ratatat12356 8 ปีที่แล้ว +19

      Strange.

    • @feallike7880
      @feallike7880 8 ปีที่แล้ว +116

      +Abominatrix650 In his defense. The books he studied aren't long enough to fit Titin in them.

    • @anonymousaubergine4455
      @anonymousaubergine4455 8 ปีที่แล้ว +9

      +Josh Marks HANK SPECIFICALLY SAID "WITH TWO 'I' ". HOW COULD YOU????? Titin*

    • @cynthiafairchild7629
      @cynthiafairchild7629 5 ปีที่แล้ว +3

      what is longer, our DNA strands or 'Titin'

    • @eminemlandsteiner168
      @eminemlandsteiner168 5 ปีที่แล้ว +25

      it's also known as Connectin, so he may know the other name

  • @aysiasantana5862
    @aysiasantana5862 9 ปีที่แล้ว +128

    an 80000 letter word?
    ain't nobody got time for that...

    • @guitarhero-sd1mp
      @guitarhero-sd1mp 9 ปีที่แล้ว

      ikr

    • @FROPDESAI
      @FROPDESAI 9 ปีที่แล้ว +10

      guitarhero5437 Except the guy who wrote the entire thing in the video. I feel sorry for that man...

    • @Unanimious
      @Unanimious 9 ปีที่แล้ว +2

      Aysia Milaan Lol u got top comment on this vid too?

    • @abcbassabc
      @abcbassabc 9 ปีที่แล้ว +2

      Aysia Milaan Try 189,000+!

  • @gracelucille5034
    @gracelucille5034 ปีที่แล้ว +6

    All the comments from 5-7 years ago and here I am in 2022 studying for my midterm thank you crash course

  • @hawksred20
    @hawksred20 8 ปีที่แล้ว +55

    Wow, great video. Only like ten percent of it stuck, possibly less but it's still a good video.

  • @sarahholland5980
    @sarahholland5980 7 ปีที่แล้ว +213

    thank you for making biology relatable and understandable!!!

  • @hobobobmarlyguy
    @hobobobmarlyguy 9 ปีที่แล้ว +58

    I failed my test because I spent two hours looking up and creating a hot pocket rather than studying for my bio test....

  • @totallymcmylastname9077
    @totallymcmylastname9077 8 ปีที่แล้ว +20

    This taught me, in 11 minutes, what an entire chapter in my entire textbook's failed to. Thanks for such an amazing content!

  • @jackpistone8015
    @jackpistone8015 8 ปีที่แล้ว +46

    Macro-evolution truly is insane. The fact that a bunch of subatomic particles can create intelligence from only wanting to bind with each other. And then the intelligence is capable of seeing and studying these particles! Amazing.

    • @daverobson3084
      @daverobson3084 6 ปีที่แล้ว +1

      Jack Pistone...So. You just made up your own idea of what evolution is. Then called that idea insane. Nice strawman there sir. Very nice indeed.

    • @aceuksy
      @aceuksy 5 ปีที่แล้ว +3

      Dave Robson it's actually thing. In sombre circles there is a debate between whether or not evolution exists or if it is exclusively on the microscopic level.

    • @LD-2401
      @LD-2401 4 ปีที่แล้ว +1

      Both micro and macro evolution exist, they can't exist without each other. I understand you were being sarcastic but I say really look into evolution. It is truly amazing, even if a little insane

  • @saamay1
    @saamay1 8 ปีที่แล้ว +38

    college senior...still needs crash course xD

  • @amandawatson8321
    @amandawatson8321 9 ปีที่แล้ว +27

    I would not have passed AP Biology without these videos

    • @tablo1394
      @tablo1394 4 ปีที่แล้ว

      Amanda Watson wait that’s an actual thing

  • @mihirp9546
    @mihirp9546 8 ปีที่แล้ว +189

    Is no one going to talk about 2:34 - 2:38? lmao

    • @madou1666
      @madou1666 8 ปีที่แล้ว +15

      +Mihir P Hilarious, he does it again at 12:36

    • @wraithbackup4286
      @wraithbackup4286 8 ปีที่แล้ว +2

      lmao from this titin down here

    • @abikochin2462
      @abikochin2462 7 ปีที่แล้ว +4

      put tht to 0.25 speed

    • @Patches-qm9iy
      @Patches-qm9iy 7 ปีที่แล้ว

      lol

    • @ace.sync.kronos
      @ace.sync.kronos 6 ปีที่แล้ว

      Hahaha, wow I actually didn't notice his face the first time, I was paying to much attention to the word itself.

  • @luisatinapay9299
    @luisatinapay9299 8 ปีที่แล้ว +14

    These videos are more helpful than any office hours session I've ever attended for any college science class
    -struggling nursing student

  • @gaah5
    @gaah5 7 ปีที่แล้ว +6

    I love the way he explains: easy and, at the same time, deep on the topic. Thank you very much for the classes. The edition and animations are GREAT too!

  • @AeliaReadsBooks
    @AeliaReadsBooks 10 ปีที่แล้ว +127

    they should have these vids be required watching in school

    • @DarkRelm22
      @DarkRelm22 10 ปีที่แล้ว +2

      They are at my school it's homework

    • @AeliaReadsBooks
      @AeliaReadsBooks 10 ปีที่แล้ว +2

      that's awesome

    • @ItsCooper
      @ItsCooper 10 ปีที่แล้ว +8

      My biology teacher shows us these, and I got addicted to this channel.

    • @AeliaReadsBooks
      @AeliaReadsBooks 10 ปีที่แล้ว

      that's amazing...good luck studying

    • @billsasser6422
      @billsasser6422 10 ปีที่แล้ว

      in my class we get tested on this she asks us what video we watched and then it has to be crash course bozeman or something and she asks what he compared it to and everything

  • @emilyb3525
    @emilyb3525 9 ปีที่แล้ว +13

    This video taught me more in 15 minutes than my biology teacher ever explains in a week. Basically this video alone got me a 90 on the test to thank you Hank!

  • @Saijana
    @Saijana 8 ปีที่แล้ว +6

    LOVE Crash Course! You guys perfectly condense a really complex and complicated subject into like 15 minutes and present it in a way that is super easy to grasp. Y'all are my HEROES!

  • @skuttle7107
    @skuttle7107 6 ปีที่แล้ว +5

    When crash course gets you a better grade on finals than your acctual teacher 😩

  • @yaseenmahmoud8988
    @yaseenmahmoud8988 9 ปีที่แล้ว +200

    This is what i am naming my first born child. Just to bother his teachers when they introduce him. ("This is..." *Five hours later...* "Say hello class!" Am I evil?

    • @yaseenmahmoud8988
      @yaseenmahmoud8988 9 ปีที่แล้ว +21

      Dangit. I cant ruin my future childs life just by naming him... ARRGGhhh

    • @yaseenmahmoud8988
      @yaseenmahmoud8988 9 ปีที่แล้ว +5

      but i want to be mean! Titin isn't long enough! :P

    • @katsfilms7124
      @katsfilms7124 9 ปีที่แล้ว +4

      Titin's cool.

    • @zemorph42
      @zemorph42 8 ปีที่แล้ว +4

      Names don't have to mean anything or make sense. Make up a name that's easy to pronounce, but takes about 15 minutes to say.

    • @benharris8382
      @benharris8382 6 ปีที่แล้ว +5

      zemorph42 So just make the name aaaaaaaaaaaaaaaaaaahhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh

  • @fruitypebbles762
    @fruitypebbles762 10 ปีที่แล้ว +30

    Why didn't I discover these videos sooner, I could have done better on my exams :(

  • @boltcry9349
    @boltcry9349 5 ปีที่แล้ว +4

    "So grab a hot pocket"
    Me, sitting on the couch with a hot pocket: way ahead of ya buddo

  • @asmaaa5526
    @asmaaa5526 8 ปีที่แล้ว +1

    I watched a ton of central dogma related videos to wrap my head around translation but this was the only video that truly answered some burning questions for me as well as gave me some more information on protein structures in a hilariously entertaining manner. Good stuff man good stuff.

  • @jake4934
    @jake4934 10 ปีที่แล้ว +5

    Explained it better in 14(ish)minutes than my Bio teacher could in a week!

  • @maeghi
    @maeghi 10 ปีที่แล้ว +31

    "Hank Green: Better than a Hot-Pocket"

    • @andyyoung7657
      @andyyoung7657 10 ปีที่แล้ว

      Uhh, what did you do to hank???

    • @maeghi
      @maeghi 10 ปีที่แล้ว +1

      Andy young He says he's better than a Hot Pocket toward the end of the video. I think it makes a great slogan.

    • @andyyoung7657
      @andyyoung7657 10 ปีที่แล้ว +3

      Maeghi Miércoles ohh ok I thought u ate him XD

    • @pinkink1995
      @pinkink1995 9 ปีที่แล้ว

      lol XD it really is an amazing slogan..

  • @tanyaengelbrecht1871
    @tanyaengelbrecht1871 8 ปีที่แล้ว +14

    Hank is my new favorite person.

  • @bhavleensmoot1219
    @bhavleensmoot1219 8 ปีที่แล้ว +2

    Easiest way to remember the START codon for translation: school starts in August "AUG". The movement along the ribosome, the "E" site: exit site, "P" site: polypeptide chain site, and "A" site is the amino acid site. I hope that helps with remembering some information during translation!

  • @laurahufsky
    @laurahufsky 10 ปีที่แล้ว +18

    thanks for helping me through 1st year bio x

  • @TheUnheardUnspoken
    @TheUnheardUnspoken 10 ปีที่แล้ว +5

    This video is so helpful!! I learned so much more in this video than I did in 2 biology classes- Thank you Hank!

  • @reikohattori14
    @reikohattori14 8 ปีที่แล้ว +34

    Rewatching these for studying :D though sadly I need to know more than what Hank has presented lol~ solid refresher tho ^^

  • @TheEpicSauce3000
    @TheEpicSauce3000 8 ปีที่แล้ว +313

    AP exam tomorrow. Here goes nothing

    • @mariadedios9081
      @mariadedios9081 8 ปีที่แล้ว +1

      +Nakolas Lol same

    • @MrMeddyman
      @MrMeddyman 7 ปีที่แล้ว +1

      Stop enabling me

    • @seann2769
      @seann2769 7 ปีที่แล้ว +1

      what did you all get?

    • @chasingsystems
      @chasingsystems 7 ปีที่แล้ว

      what does AP mean?

    • @angelodecasas5568
      @angelodecasas5568 7 ปีที่แล้ว +5

      don't worry about it, you're not smart enough. lol

  • @TheFireflyGrave
    @TheFireflyGrave 10 ปีที่แล้ว +26

    Hank Green; better than a hot-pocket.

  • @ubiveritasetamor
    @ubiveritasetamor 10 ปีที่แล้ว +16

    Thanks so much for these awesome videos! I get so bogged down in the details and these really help me to get back to the "big picture" :)

  • @pannenkoekmetstroop
    @pannenkoekmetstroop 5 ปีที่แล้ว

    Thank you CrashCourse team!! Your content is of such great quality. Have been watching this so many times, first for my biology classes in high school and now at university for quick revision. Honestly you must have gained so many good karma points for making these videos!! Wishing you all the best from the Netherlands.

  • @TheTigero
    @TheTigero 8 ปีที่แล้ว +20

    Hank has a tick that I cannot unsee... he constantly bumps his glasses up on his nose with his finger.... 2:18

    • @TheTigero
      @TheTigero 8 ปีที่แล้ว

      sorry, more like 2:13

    • @roderickahrens5539
      @roderickahrens5539 8 ปีที่แล้ว +1

      +Kevin Klika it might just be that his glasses are not well fitted so he needs to readjust them frequently

    • @MexicanPizza44
      @MexicanPizza44 8 ปีที่แล้ว

      +Kevin Klika He could potentially consider contacts or lasik after reading your comment. :P Interesting that you noticed, btw. My brain is overloaded simply by trying to follow the biology. He speaks fast, but I like it.

    • @ratatat12356
      @ratatat12356 8 ปีที่แล้ว +2

      +Kevin Klika I assure you everyone who wears glasses does that

    • @TheTigero
      @TheTigero 8 ปีที่แล้ว

      The Great Danku Tree I wear glasses, and I understand readjusting them, but the way he hits them with his finger (and puts a big smudge on the lens) is more what my comment was about...

  • @brittanymoore3866
    @brittanymoore3866 10 ปีที่แล้ว +5

    I really enjoy your videos. I went from a C in lecture to a B within a matter of a few weeks after finding Crash Course. Thank you Hank for being awesome and funny.

  • @katiemccloskey9630
    @katiemccloskey9630 8 ปีที่แล้ว +348

    Who else is watching this 20 minutes before their honors bio exam?

    • @alexandrap.7357
      @alexandrap.7357 7 ปีที่แล้ว

      me

    • @johntitor7989
      @johntitor7989 7 ปีที่แล้ว

      Katie McCloskey Yeah

    • @sorackee
      @sorackee 6 ปีที่แล้ว +3

      How the heck did you know it was honors?? Lol

    • @void5823
      @void5823 5 ปีที่แล้ว

      Did you make it?

    • @yellowbraces
      @yellowbraces 5 ปีที่แล้ว

      Dang that's me right here and right now

  • @schwa6275
    @schwa6275 5 ปีที่แล้ว

    7 years later and this still helps me with school … amazing! Your videos truly transcend time!
    Keep up the great work!
    Yes, Hank, I think we'd all agree that you are better than a hot pocket

  • @megike55
    @megike55 4 ปีที่แล้ว

    These videos are extremely helpful. I find that the animation really helps to visualize genetic concepts that are hard to figure out from diagrams alone. Thanks Hank!

  • @taviahedrick8279
    @taviahedrick8279 5 ปีที่แล้ว +5

    I can not thank you enough for this, as well as your other videos. You make learning college biology fun and actually understandable!

    • @dylan4400
      @dylan4400 5 ปีที่แล้ว

      Tavia Hedrick I’m learning this in my freshman year :/

  • @hannahtex6768
    @hannahtex6768 8 ปีที่แล้ว +5

    You just gave me more information in 14 minutes then my lecture teacher gives me in 5 hours and it was easier to understand... Thanks :)

  • @audryklein
    @audryklein 6 ปีที่แล้ว

    I love all of these they are SO FREAKING HELPFUL WITH THE EXPLANATIONS and table of contents. Thank you so much

  • @colleenweinburke382
    @colleenweinburke382 7 ปีที่แล้ว

    he is the reason I pass my biology tests. After j watch his videos I go through my notes again, and then they make sense.
    Also I have a good biology teacher but having it all compacted and visual is a blessing.

  • @Nikkerman
    @Nikkerman 10 ปีที่แล้ว +6

    My mom "What are you doing waching videos, you need to study for biolo... Oh you are. My bad" me:" L0L"

  • @lailaschutte2017
    @lailaschutte2017 7 ปีที่แล้ว +3

    A BIG THANK YOU FROM GERMANY! You really helped me getting through my exams with the funny and informative way of teaching these complexe topics!
    Without your videos studying really sucks... :)

  • @Thom.sullivan
    @Thom.sullivan 6 ปีที่แล้ว

    I don't think that I can express my appreciation for these videos. Crash course biology is the only thing getting me through AP biology. Hank green, you are my hero.

  • @bachucho29
    @bachucho29 6 ปีที่แล้ว

    Thanks thanks thanks soo much these series help me understand what I'm learning in the classroom much better. I can see all the dedication and hard work that's behind these videos and they come out beautifully. I always enjoy learning with you, awesome work!

  • @jessicarapier464
    @jessicarapier464 7 ปีที่แล้ว +76

    College Biology Exam tomorrow. You just saved my grade!

  • @TheDatolo97
    @TheDatolo97 10 ปีที่แล้ว +4

    I have a test tomorrow on this subject, you helped me very much!

  • @barbaramaclaycameron3952
    @barbaramaclaycameron3952 7 ปีที่แล้ว +2

    Hi Hank--my students and I love your videos. Have you every considered doing a short series on the discoveries that led up to these concepts, especially all of the molecular biology? I know some things, and have been able to research others, but would love to have it all collected in one place! Then I wouldn't so often be stumped by questions like "how do they know that DNA polymerase is the enzyme that connects the Okazaki fragements" and "how do they know ribosomes have 2 sub-units" and "how did they figure out which codon codes for which amino acid"? (you can see I have students that prefer not to take things on faith!!).

  • @nicolesagarnaga4952
    @nicolesagarnaga4952 8 ปีที่แล้ว

    I have a bio test over this tomorrow and I've missed so much school when we were learning it you're literally my life saver

  • @sprayartist8459
    @sprayartist8459 8 ปีที่แล้ว +7

    I can make the word go in whatever direction I want it to go, if I want it to go right, it goes right and vice versa. Try it and amaze yourself.

  • @abrahamvivas9540
    @abrahamvivas9540 9 ปีที่แล้ว +7

    This is amazing, i'm mechanical engineer (not english native speaker) and i'm understanding everything in this series of videos; the nature is amazing, how through evolution it has created this enormous machinery that can store and use information to make and incredibly complex machine like multicelular living beings!

    • @debbieeberle-sherman4372
      @debbieeberle-sherman4372 9 ปีที่แล้ว +1

      "evolution......created.... machinery....information... complex machine....". since evolution is the antithesis of creation, this sentence would make sense if "God" was substituted for "evolution". It seems you are demonstrating the accuracy of Romans 1:20, Abraham "For since the creation of the world God’s invisible qualities-his eternal power and divine nature-have been clearly seen, being understood from what has been made, so that people are without excuse." Clearly you know machines are "created" - so why not acknowledge the Creator?

    • @Jasonmanmosa
      @Jasonmanmosa 9 ปีที่แล้ว +8

      Debbie Eberle-Sherman well with that same logic if something incredibly complex must be created then who created God? And who created the creator of God?

    • @elizavetahedervary3287
      @elizavetahedervary3287 9 ปีที่แล้ว

      Kyle a The concept of 'God' is an intelligent being that does not have a creator. What effect this has on your beliefs I'm not really sure. Also, there is such a thing as 'God-guided evolution'--the belief that a deity controlled evolution's path. Then again, it's up to you whether you think it's right or not. I'll be waiting here with popcorn, a Swiss flag and the WWE championship belt.
      On an unrelated note, hot pockets are yummy.
      On another unrelated note, some Chinese dude managed to memorize >140,000 digits of pi. Who knows what he could do with that protein?

    • @elizavetahedervary3287
      @elizavetahedervary3287 9 ปีที่แล้ว

      ***** YES. That's the sort of person we need.

    • @philippaswindells9310
      @philippaswindells9310 9 ปีที่แล้ว

      Elizaveta Hedervary my atheism is being shaken by this, as well as several other elements of science.
      I've heard Richard Dawkins hypothesised this complex life might have originally come from, basically, ETs, seeding this planet. Intentionally, or accidentally. I wouldn't have expected that kind of theory to come from someone like him, although it seems vaguely plausible to me.
      Can someone please explain to me what other 'best guesses' the atheist camp have for how we could possibly have evolved a genetic code, billions of characters long that contains information to create amino acids in the exact right combination for them to actually make functional proteins? I think Steven Myer said the chance of a typical 150 amino acid long protein was 10 to the 164th power.
      So chance is out, natural selection couldn't account for this complexity existing from the first cell, so what do we have?
      Again, I was brought up an atheist, I'm not looking at science and trying to make it fit my existing religious beliefs, I don't have any, but seriously, this looks exactly like a computer code, and those surely don't come about by chance, natural law, or any combination of the two.

  • @boohoo6169
    @boohoo6169 4 ปีที่แล้ว +1

    I swear to god these crash course videos are more valuable than both my high school and college educations combined

  • @mashayluhhh
    @mashayluhhh 8 ปีที่แล้ว +2

    Thank you so much for making all of your videos, theyre so very helpful!

  • @swaira0_o451
    @swaira0_o451 7 ปีที่แล้ว +3

    ive been watching this video for hours LITERALLY!! Finally got a bit of it iN ma head ..phew thnx :P

  • @kathrynbarndt123
    @kathrynbarndt123 9 ปีที่แล้ว +16

    Hank is left-handed YES!!!!

  • @elysan612
    @elysan612 5 ปีที่แล้ว

    Crash course helped me pass my psychology class in college, now I'm back for biology, so thank you for all that you do.

  • @thenicksterfly
    @thenicksterfly 8 ปีที่แล้ว

    These videos literally save my bio grade. Like I don't know what I would do without them. Thank you for being a better bio teacher than my actual bio teacher.

  • @nobody-nj4jg
    @nobody-nj4jg 4 ปีที่แล้ว +8

    Who else watching in quarantine?

  • @sct9852
    @sct9852 10 ปีที่แล้ว +3

    You just saved me for my biology exam on Thursday. Holy crap.

  • @deborahnelson4057
    @deborahnelson4057 7 ปีที่แล้ว

    Thanks for all your help Hank, Love the fun way you explain it all!

  • @wuigi1496
    @wuigi1496 8 ปีที่แล้ว +2

    Hank, everyone i know at sixth form loves you, keep going buddy!

  • @joshxzy
    @joshxzy ปีที่แล้ว +4

    Watch me pass my biology final exam (i'll come back)

  • @Thurgor_Supreme
    @Thurgor_Supreme 10 ปีที่แล้ว +30

    Someone should make a nerdrock parody band called AT/GC
    ...anyone?

    • @alphonseelric22
      @alphonseelric22 10 ปีที่แล้ว +2

      That would be super awesome!

    • @RabidLeroy
      @RabidLeroy 7 ปีที่แล้ว +1

      Thurgor Supreme With their hit song "DNA (Oi!)"

  • @NyanLama459
    @NyanLama459 6 ปีที่แล้ว

    This channel is insanely good at getting the point across with minimal confusion. Hank speaks at 200% the speed of a teacher yet he is 1000% more understandable.

  • @annalane1829
    @annalane1829 7 ปีที่แล้ว +1

    Thank you so much! i have no idea what i would do without crash course! It makes biology understandable and easy.