The series is really so informative and was presented in a very smooth and easy to understand sequence and illustrations. There were other same videos for hematology subject but this one is so easy to comprehend. Thank you very much. Hope you can still continue doing this for further learning on the same subject.
By definition, the reticulocyte stage begins with the loss of the normoblast nucleus and ends once all the rna, dna and organelles have disappeared. The spleen does help maturation, likely through a macrophage mediated process, but in splenectomy patients the liver and bone marrow can take over this function.
reticulocytes/polychromatic erythrocyte dont have nucleus anymore. the last stage of RBC precursor, wherein there is still nucleus, is orthochromic erythroblast.
Sir... What happens to reticulocytes in the spleen how they become mature RBC with the help of spleenic macrophages... what's the mechanism? ... could you please reply...
700th like... 73rd comment, my roll no. is also 73 & loving hematology.. ur way of speaking makes it like a bed time story & I can hear these all day. Thank you 😊
I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis! Please, can u clarify that? Thanks in advance.
Good presentation but I have some queries: You did not show the origin of the megakaryoblasts, is it from the stem cell or from the myeloid ?! Also, how can we know that there are polychromatic erythrocytes in the blood? So do we have to divide the result of retic index by 2 for all patients?
Hi I also wondering how can we know there are polychromatic erythrocytes?if so do we divide the result by 2? Is it define by blueish blood smear result
I thought a recticulocyte count was a single test with a single figure. But I have seen a blood test where it is broke down to immature retic count, retic hb level, retic fraction and percentage hyperchromatic cell. Have you a video explaining the highs and lows of these please?
My name is Tanya (I'm using my husband's account, apologies!) I am an MLS studying for my certification exam. In the laboratory, we define polychromasia qualitatively. Usually, polychromasia is reported on a range of slight to marked. Is there any difference in the calculation for a corrected reticulocyte count between a patient displaying slight polychromasia (one to two cells per field) versus marked polychromasia (over 50% of the field)?
Thanks a lot for your great efforts, May God bless you hundreds of times. I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis! Hopefully, you have time to get back to me. Thanks in advance.
@@MedicosisPerfectionalis Imagine there is no stain, if you were to see a skeleton, that somehow has living bones, would the bones produce enough reticulocytes to be seen by an observer, if so what might this look like? Might they look something like blood?
Thank you so much for these wonderful videos, One question though.; why do we multiply by 10 when calculating MCV and MCH and 100 when calculating MCHC?
@@MedicosisPerfectionalis No your speech style is good, not giving info at a fast pace, tks for the video and beautiful animation, really fun to learn this way
CORRECTION : I made a mistake, Reticulocytes have NO nucleus!
The series is really so informative and was presented in a very smooth and easy to understand sequence and illustrations. There were other same videos for hematology subject but this one is so easy to comprehend. Thank you very much. Hope you can still continue doing this for further learning on the same subject.
Thanks a million for your kind words...You made my day...and, yes, I will continue making more videos!
By definition, the reticulocyte stage begins with the loss of the normoblast nucleus and ends once all the rna, dna and organelles have disappeared. The spleen does help maturation, likely through a macrophage mediated process, but in splenectomy patients the liver and bone marrow can take over this function.
Nuclear remanants
I was just coming to query this because I know in the rbc cell lineage the nucleus and mitochondria are ejected during the orthochromatic stage.
I was literally taken aback by the level of detail you've crammed into such a short video. I'll be forever grateful to you, Thank you SO much!!
You’re so welcome! I do a lot of research before I make this videos....Thanks for your kind words...Don’t forget to subscribe!
reticulocytes/polychromatic erythrocyte dont have nucleus anymore. the last stage of RBC precursor, wherein there is still nucleus, is orthochromic erythroblast.
You have a knack for explaining concepts! Thank you
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Great presentation, however Reticulocytes are NOT nucleated
I think you are right...My apologies...Thanks for correcting me...I will right an addendum in the description...Thanks again!
write* :)
Good video!
LoL! Haha! Silly mistake:)
Thank you so much, I passed my test in October, 2022.
Congratulations!
U r best explains the hematology
Thanks 🙏
Thank you .. Sir ... I’m so glad I found this channel ..
You’re very welcome! Glad to have you here!
Sir... What happens to reticulocytes in the spleen how they become mature RBC with the help of spleenic macrophages... what's the mechanism? ... could you please reply...
Retics can be calculated as an absolute number when calculated with a RBC
Glad to have found you at the beginning of my semester ❤ we have a long journey together ahead of us
Which college
Sorry, I didn't understand when can I do the additional correction for polychromasia
Excellent way of explanation with beautiful voice
Thanks ☺️
Thank you... I appreciate these videos so much! you are my hero
My pleasure 😇
So now reticulum cells of the (Reticuloendothelial system) are different from the reticulocyte right ??
How would we know if a patient has polychromasia when interpreting labs
700th like... 73rd comment, my roll no. is also 73 & loving hematology.. ur way of speaking makes it like a bed time story & I can hear these all day. Thank you 😊
Thank you so much 😊
I appreciate it!
Medicine is wonderful
@@MedicosisPerfectionalis wlcm.. yeah it is!!💝
Great 👍
sir, is there any death rate in the maintenance of apml4
Why we correct reticulocyte count
Different grades of reticulocyte in supra vital stain , how will it cause error in manual reticulocyte count?
I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis!
Please, can u clarify that?
Thanks in advance.
Pls explain this
Good presentation but I have some queries: You did not show the origin of the megakaryoblasts, is it from the stem cell or from the myeloid ?! Also, how can we know that there are polychromatic erythrocytes in the blood? So do we have to divide the result of retic index by 2 for all patients?
I talked about megakaryocytes and megakaryoblast in a separate video titled “megakaryocytes”
Hi I also wondering how can we know there are polychromatic erythrocytes?if so do we divide the result by 2? Is it define by blueish blood smear result
I thought a recticulocyte count was a single test with a single figure. But I have seen a blood test where it is broke down to immature retic count, retic hb level, retic fraction and percentage hyperchromatic cell. Have you a video explaining the highs and lows of these please?
No, I don’t...My videos are simplified...In reality, there are many sophisticated tests.
made my concept clear
Thanks 🙏
My name is Tanya (I'm using my husband's account, apologies!) I am an MLS studying for my certification exam. In the laboratory, we define polychromasia qualitatively. Usually, polychromasia is reported on a range of slight to marked. Is there any difference in the calculation for a corrected reticulocyte count between a patient displaying slight polychromasia (one to two cells per field) versus marked polychromasia (over 50% of the field)?
Thanks a lot for your great efforts, May God bless you hundreds of times.
I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis!
Hopefully, you have time to get back to me.
Thanks in advance.
Reticulocyte count should be increased in anemia it is effective erythropoiesis if not it is ineffective erythropoiesis
Do reticulocytes have a color on their own?
Using which stain?
@@MedicosisPerfectionalis
Imagine there is no stain, if you were to see a skeleton, that somehow has living bones, would the bones produce enough reticulocytes to be seen by an observer, if so what might this look like?
Might they look something like blood?
thank u for this beautiful presentation
My pleasure!
Thank you so much for these wonderful videos, One question though.; why do we multiply by 10 when calculating MCV and MCH and 100 when calculating MCHC?
Just to make the numbers cool and similar “20, 30,...etc.” instead of 20 and 3.
Just found your channel, amazing work!
Thanks, bro
Fine information
Indebted to you sir, for making all this easy & understandable 🙏🙏🙏
شكرا ...😍😍
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ALI GHANEM تراه اجنبي 😂؟
مدا افهم عليه ممكن توضيح لطريقة الحساب
Amazing bro. but reticulocytes have no nuclei
very productive lecture . Thank you so much
You’re always welcome, dear :)
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What means to high RET-He?
Thank you so much for your class, if I have blood report need your review and opinion,any email we can send to?
medicosisperfectionalis@gmail.com
kindly share video for peripheral smear visualization
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Any cardiology stuff coming up?? I neeeeeed that pls
Not yet!
I am sorry 😐
Thanks a lot
My pleasure 😇
Thanks sir so helpful
☺
My pleasure!
Thnkxx alot once again...👍👍
My pleasure 😇❤️
Please also make rheumatology videos
It's here: goo.gl/xfJKL1
Thank u
Yeah 👍
Sir reticulocytes are non- nucleated i think????
They’re not.
You are the best !plz make more videos about neurology
How reticulocyte count is used to assess the effectiveness of treatment of anemia?
When they normalize, it’s a good sign.
How do u make ur videos
What do you mean?
Can you elaborate, please?
Awesome work 👏
Thanks 🙏
Thank you sir 💜💜
You’re very welcome!
wonderful
Thank you so much! Best of luck!
Thank you so much..
You bet 👍
yh king
Thank you!
Lucky number three
It looks like the host of this video is drunk. Hahahaha but I love how the explain
Is your accent Russian?
Nope!
Medicosis Perfectionalis Where are you from? I like the accent
Medicosis Perfectionalis Is it German then?... lol..Russian is a better salad dressing.. but I like German potato salad... ahaha
Egyptian
Thank you very much
Are you Americans or What ?
He is from Egypt.
I confirm
✅✅✅✅
Thank you 🙏
OMG❤
🙏
Couldn’t listen you for more than couple minutes.. sorry its me not you
You’re fine
You can play at 2x speed
Your speech style is very distractive !!!!
Ok
@@MedicosisPerfectionalis No your speech style is good, not giving info at a fast pace, tks for the video and beautiful animation, really fun to learn this way
Man you are gangerous
Excellent way of explanation with beautiful voice
sir, is there any death rate in the maintenance of apml4