Reticulocytes

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  • เผยแพร่เมื่อ 14 ก.ย. 2017
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    The doubly corrected reticulocyte count is now called Reticulocyte production index.
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ความคิดเห็น • 132

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  6 ปีที่แล้ว +187

    CORRECTION : I made a mistake, Reticulocytes have NO nucleus!

    • @rolandovaldez722
      @rolandovaldez722 6 ปีที่แล้ว +9

      The series is really so informative and was presented in a very smooth and easy to understand sequence and illustrations. There were other same videos for hematology subject but this one is so easy to comprehend. Thank you very much. Hope you can still continue doing this for further learning on the same subject.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 ปีที่แล้ว +6

      Thanks a million for your kind words...You made my day...and, yes, I will continue making more videos!

    • @housedoctor7140
      @housedoctor7140 5 ปีที่แล้ว +6

      By definition, the reticulocyte stage begins with the loss of the normoblast nucleus and ends once all the rna, dna and organelles have disappeared. The spleen does help maturation, likely through a macrophage mediated process, but in splenectomy patients the liver and bone marrow can take over this function.

    • @gems1717
      @gems1717 4 ปีที่แล้ว +1

      Nuclear remanants

    • @nyasha7721
      @nyasha7721 3 ปีที่แล้ว

      I was just coming to query this because I know in the rbc cell lineage the nucleus and mitochondria are ejected during the orthochromatic stage.

  • @rockycycle2682
    @rockycycle2682 6 ปีที่แล้ว +46

    I was literally taken aback by the level of detail you've crammed into such a short video. I'll be forever grateful to you, Thank you SO much!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 ปีที่แล้ว +7

      You’re so welcome! I do a lot of research before I make this videos....Thanks for your kind words...Don’t forget to subscribe!

  • @bayonaar
    @bayonaar 6 ปีที่แล้ว +19

    reticulocytes/polychromatic erythrocyte dont have nucleus anymore. the last stage of RBC precursor, wherein there is still nucleus, is orthochromic erythroblast.

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  2 ปีที่แล้ว +3

    💊🦠 Antibiotics Course: www.medicosisperfectionalis.com/
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  • @ivo3185
    @ivo3185 3 ปีที่แล้ว +3

    You have a knack for explaining concepts! Thank you

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  10 หลายเดือนก่อน +3

    🩸 Hematology Playlist: th-cam.com/play/PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU.html&si=tomFsUjAgOKhOJVq

  • @qureshiqureshi9274
    @qureshiqureshi9274 4 ปีที่แล้ว +1

    Excellent way of explanation with beautiful voice

  • @ritikasrivastava4084
    @ritikasrivastava4084 ปีที่แล้ว

    Indebted to you sir, for making all this easy & understandable 🙏🙏🙏

  • @adin200
    @adin200 4 ปีที่แล้ว +4

    Thank you... I appreciate these videos so much! you are my hero

  • @nathanael2345
    @nathanael2345 5 ปีที่แล้ว +2

    Just found your channel, amazing work!

  • @meryemlahbara9669
    @meryemlahbara9669 5 ปีที่แล้ว +3

    Thank you .. Sir ... I’m so glad I found this channel ..

  • @behappy6484
    @behappy6484 ปีที่แล้ว +1

    Sir... What happens to reticulocytes in the spleen how they become mature RBC with the help of spleenic macrophages... what's the mechanism? ... could you please reply...

  • @sarangas8688
    @sarangas8688 4 ปีที่แล้ว +1

    Different grades of reticulocyte in supra vital stain , how will it cause error in manual reticulocyte count?

  • @TRUESTRIVER40
    @TRUESTRIVER40 6 ปีที่แล้ว +3

    thank u for this beautiful presentation

  • @Tonnie31
    @Tonnie31 3 ปีที่แล้ว +1

    How would we know if a patient has polychromasia when interpreting labs

  • @rahmahl5762
    @rahmahl5762 4 ปีที่แล้ว +1

    So now reticulum cells of the (Reticuloendothelial system) are different from the reticulocyte right ??

  • @Roon864
    @Roon864 4 ปีที่แล้ว

    You are the best !plz make more videos about neurology

  • @mano1758
    @mano1758 2 ปีที่แล้ว +1

    Why we correct reticulocyte count

  • @4033mitchell
    @4033mitchell 3 ปีที่แล้ว +1

    Retics can be calculated as an absolute number when calculated with a RBC

  • @amarverma3983
    @amarverma3983 5 ปีที่แล้ว +2

    U r best explains the hematology

  • @manarsmaan2624
    @manarsmaan2624 2 ปีที่แล้ว +1

    very productive lecture . Thank you so much

  • @debabratsarma6863
    @debabratsarma6863 3 ปีที่แล้ว +1

    sir, is there any death rate in the maintenance of apml4

  • @christopherseifried5566
    @christopherseifried5566 3 ปีที่แล้ว +1

    My name is Tanya (I'm using my husband's account, apologies!) I am an MLS studying for my certification exam. In the laboratory, we define polychromasia qualitatively. Usually, polychromasia is reported on a range of slight to marked. Is there any difference in the calculation for a corrected reticulocyte count between a patient displaying slight polychromasia (one to two cells per field) versus marked polychromasia (over 50% of the field)?

  • @fme5152
    @fme5152 5 ปีที่แล้ว +15

    Great presentation, however Reticulocytes are NOT nucleated

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว +2

      I think you are right...My apologies...Thanks for correcting me...I will right an addendum in the description...Thanks again!

    • @xDomglmao
      @xDomglmao 5 ปีที่แล้ว +2

      write* :)
      Good video!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว +2

      LoL! Haha! Silly mistake:)

  • @kevkonk
    @kevkonk 4 ปีที่แล้ว +2

    I thought a recticulocyte count was a single test with a single figure. But I have seen a blood test where it is broke down to immature retic count, retic hb level, retic fraction and percentage hyperchromatic cell. Have you a video explaining the highs and lows of these please?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +2

      No, I don’t...My videos are simplified...In reality, there are many sophisticated tests.

  • @karamellboo690
    @karamellboo690 3 ปีที่แล้ว +1

    Sorry, I didn't understand when can I do the additional correction for polychromasia

  • @madhukardeshpande563
    @madhukardeshpande563 5 ปีที่แล้ว +1

    Fine information

  • @TheAwassyable
    @TheAwassyable ปีที่แล้ว +3

    Thank you so much, I passed my test in October, 2022.

  • @mageropeter1752
    @mageropeter1752 9 หลายเดือนก่อน +1

    Glad to have found you at the beginning of my semester ❤ we have a long journey together ahead of us

  • @nkazimulomashobane3960
    @nkazimulomashobane3960 4 ปีที่แล้ว +3

    Thank you so much for these wonderful videos, One question though.; why do we multiply by 10 when calculating MCV and MCH and 100 when calculating MCHC?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      Just to make the numbers cool and similar “20, 30,...etc.” instead of 20 and 3.

  • @shutterismmn
    @shutterismmn 4 ปีที่แล้ว +2

    made my concept clear

  • @poornimachowdary1911
    @poornimachowdary1911 4 ปีที่แล้ว

    Awesome work 👏

  • @kumaradarsh3983
    @kumaradarsh3983 4 ปีที่แล้ว

    How reticulocyte count is used to assess the effectiveness of treatment of anemia?

  • @wyskun
    @wyskun ปีที่แล้ว

    What means to high RET-He?

  • @xavii2794
    @xavii2794 6 ปีที่แล้ว +2

    Thank you sir 💜💜

  • @fromhavenk7112
    @fromhavenk7112 5 ปีที่แล้ว +2

    Thnkxx alot once again...👍👍

  • @bikramadityakumar3612
    @bikramadityakumar3612 5 ปีที่แล้ว +2

    Thanks a lot

  • @alighanem3005
    @alighanem3005 6 ปีที่แล้ว +6

    شكرا ...😍😍

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 ปีที่แล้ว

      😊👍👍

    • @xavii2794
      @xavii2794 6 ปีที่แล้ว

      ALI GHANEM تراه اجنبي 😂؟

    • @user-ej1rd3bm3y
      @user-ej1rd3bm3y 5 ปีที่แล้ว

      مدا افهم عليه ممكن توضيح لطريقة الحساب

  • @haideralshreefy1569
    @haideralshreefy1569 6 ปีที่แล้ว +2

    wonderful

  • @qosayjabr
    @qosayjabr 3 ปีที่แล้ว +2

    I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis!
    Please, can u clarify that?
    Thanks in advance.

  • @sherlocktripathi4529
    @sherlocktripathi4529 4 ปีที่แล้ว +3

    700th like... 73rd comment, my roll no. is also 73 & loving hematology.. ur way of speaking makes it like a bed time story & I can hear these all day. Thank you 😊

  • @jacksparrow-wq1pb
    @jacksparrow-wq1pb 3 หลายเดือนก่อน

    Super information time ❤❤❤❤❤❤

  • @mehnazghafoor2912
    @mehnazghafoor2912 5 ปีที่แล้ว +2

    Thanks sir so helpful

  • @nsas955
    @nsas955 4 ปีที่แล้ว +1

    Good presentation but I have some queries: You did not show the origin of the megakaryoblasts, is it from the stem cell or from the myeloid ?! Also, how can we know that there are polychromatic erythrocytes in the blood? So do we have to divide the result of retic index by 2 for all patients?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      I talked about megakaryocytes and megakaryoblast in a separate video titled “megakaryocytes”

    • @Nice-vx4dr
      @Nice-vx4dr 2 ปีที่แล้ว

      Hi I also wondering how can we know there are polychromatic erythrocytes?if so do we divide the result by 2? Is it define by blueish blood smear result

  • @shutterismmn
    @shutterismmn 4 ปีที่แล้ว +1

    kindly share video for peripheral smear visualization

  • @mohebMJ13022011
    @mohebMJ13022011 3 ปีที่แล้ว +3

    Thanks a lot for your great efforts, May God bless you hundreds of times.
    I am confused about the normal percentage of reticulocytes, You said it is normal if it is less than 3% But in the end, you said if it is less than 3% that indicates bad bone marrow and ineffective erythropoiesis!
    Hopefully, you have time to get back to me.
    Thanks in advance.

    • @mohammedibraheemkarpoor8605
      @mohammedibraheemkarpoor8605 2 ปีที่แล้ว +1

      Reticulocyte count should be increased in anemia it is effective erythropoiesis if not it is ineffective erythropoiesis

  • @keratinpearls5058
    @keratinpearls5058 2 ปีที่แล้ว +1

    How do u make ur videos

  • @farahhisham884
    @farahhisham884 4 ปีที่แล้ว +1

    Any cardiology stuff coming up?? I neeeeeed that pls

  • @devinm.6149
    @devinm.6149 3 ปีที่แล้ว +1

    Do reticulocytes have a color on their own?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 ปีที่แล้ว

      Using which stain?

    • @devinm.6149
      @devinm.6149 3 ปีที่แล้ว

      @@MedicosisPerfectionalis
      Imagine there is no stain, if you were to see a skeleton, that somehow has living bones, would the bones produce enough reticulocytes to be seen by an observer, if so what might this look like?
      Might they look something like blood?

  • @Sciencosis_ExcEptionalis
    @Sciencosis_ExcEptionalis 8 หลายเดือนก่อน

    Amazing bro. but reticulocytes have no nuclei

  • @abelserenayu2910
    @abelserenayu2910 2 ปีที่แล้ว +2

    Thank you so much for your class, if I have blood report need your review and opinion,any email we can send to?

  • @fatimasuleman1980
    @fatimasuleman1980 5 ปีที่แล้ว +2

    Please also make rheumatology videos

  • @SeemaSharma-cb9gd
    @SeemaSharma-cb9gd ปีที่แล้ว

    Sir reticulocytes are non- nucleated i think????

  • @fatimasuleman1980
    @fatimasuleman1980 5 ปีที่แล้ว +2

    Thank you so much..

  • @MTVFrMTuRkS-_-
    @MTVFrMTuRkS-_- 3 ปีที่แล้ว +2

    yh king

  • @joanpinto9943
    @joanpinto9943 3 ปีที่แล้ว +1

    It looks like the host of this video is drunk. Hahahaha but I love how the explain

  • @Mgsogs
    @Mgsogs ปีที่แล้ว

    Lucky number three

  • @mohamedelshopaky2688
    @mohamedelshopaky2688 5 ปีที่แล้ว +1

    Thank you very much
    Are you Americans or What ?

  • @user-yf8iv2fl6l
    @user-yf8iv2fl6l ปีที่แล้ว

    OMG❤

  • @winterfawn9762
    @winterfawn9762 4 ปีที่แล้ว +2

    Is your accent Russian?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +2

      Nope!

    • @winterfawn9762
      @winterfawn9762 4 ปีที่แล้ว +1

      Medicosis Perfectionalis Where are you from? I like the accent

    • @winterfawn9762
      @winterfawn9762 4 ปีที่แล้ว +1

      Medicosis Perfectionalis Is it German then?... lol..Russian is a better salad dressing.. but I like German potato salad... ahaha

    • @Krayzie718
      @Krayzie718 4 ปีที่แล้ว +1

      Egyptian

  • @asdssa2714
    @asdssa2714 3 ปีที่แล้ว +1

    ✅✅✅✅

  • @noorhashmi4
    @noorhashmi4 5 ปีที่แล้ว +1

    Couldn’t listen you for more than couple minutes.. sorry its me not you

  • @Rendezvous89
    @Rendezvous89 4 ปีที่แล้ว +1

    Your speech style is very distractive !!!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      Ok

    • @ansonchanhahaha
      @ansonchanhahaha 2 ปีที่แล้ว

      @@MedicosisPerfectionalis No your speech style is good, not giving info at a fast pace, tks for the video and beautiful animation, really fun to learn this way

  • @deniswolf1998
    @deniswolf1998 ปีที่แล้ว

    Man you are gangerous

  • @debabratsarma6863
    @debabratsarma6863 3 ปีที่แล้ว +1

    sir, is there any death rate in the maintenance of apml4

  • @qureshiqureshi9274
    @qureshiqureshi9274 4 ปีที่แล้ว +1

    Excellent way of explanation with beautiful voice