All About LPS and Endotoxemia

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  • เผยแพร่เมื่อ 23 ก.ค. 2024
  • LPS (aka "Endotoxin") is a highly inflammatory molecule made by gram-negative bacteria in our guts. When you have dysbiosis (an imbalance between the good and the bad bacteria) LPS can be overly abundant and wreak havoc on your body and cause a lot of inflammation. In this video we'll discuss what LPS does to your gut and what it does when it gets through a leaky gut (wall)!
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    These things help me grow the channel and make more videos : )
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    Dr. Nicole DiNezza, DC, NTP
    Holly Springs, NC

ความคิดเห็น • 51

  • @twainmom4999
    @twainmom4999 2 ปีที่แล้ว

    Fantastic video...important missing puzzle pieces on my journey to wellness. Thank you! Your content is very valuable to those of us who have suffered for years with no resolution.

  • @franzbuchel7295
    @franzbuchel7295 2 ปีที่แล้ว +1

    Excellent video giving proof of your deep knowledge- this is very rare! Thank You!

  • @Thomas_Mathew_May
    @Thomas_Mathew_May 3 ปีที่แล้ว +3

    Just wanted to let you know how much I appreciate your channel! Your videos have really helped me put things into perspective and talk myself off the “restriction ledge” quite a few times. I also really love the podcast you have with Amy. Always puts me in a good mood. Thanks a bunch!

    • @gutmicrobiomequeen
      @gutmicrobiomequeen  3 ปีที่แล้ว

      🥰🥰🥰🥰🥰 thank you so much for commenting Thomas!

  • @heartsoulholisticservices
    @heartsoulholisticservices ปีที่แล้ว +4

    Thank you for this informative video! I had requested I be checked and found I have high LPS (IgG and IgA) and my functional at doctor at the time never suggested a binder. My new naturopath never did either. My main symptom is inflammatory, painful acne and soreness on my face. I did some investigative work and remembered a moment when my skin was clear and healthy, despite eating food sensitivities. I was taking Microbiome Labs Mega IgG 2000. It was like a light bulb went off. I start restarted it and my skin issues have subsided, almost over night. I am surprised my holistic docs couldn't figure this out! I plan to stay on this while we kill SIBO (die off) and rebuild my gut. I appreciate the work you do!

    • @SpectrumOfChange
      @SpectrumOfChange 11 หลายเดือนก่อน

      Wow, congratulations on figuring this out!!

    • @SeventhMark
      @SeventhMark 4 หลายเดือนก่อน

      Im gonna try an IgG binder ASAP!

  • @amahlvanhalsema8188
    @amahlvanhalsema8188 3 วันที่ผ่านมา

    Great video, thanks!

  • @Mourne84
    @Mourne84 ปีที่แล้ว +2

    I think there was a paper on a study done with lps in association with vitamin C or orange juice, and the group with the juice reduced greatly the inflammation after eating lps/saturated fat. It's interesting thanks.

  • @jbvibrations
    @jbvibrations 3 ปีที่แล้ว +3

    Thank you ! Amazing channel. Exactly what I needed. I started a low Fodmap diet about two weeks ago and it has basically ended my long term diarrhea, thank god, though I am worried about the lack of diversity in the diet, a concern you share. I think my fat soluble vitamins were fairly depleted, so it’s probably worth it for the short term to regain those a bit. I try to get small doses of things in there to mitigate adverse affects; I take psyllium and eat all the resistant starches I can, unsweetened chocolate in oat bran, cold potato and rice, polyphenols, a fair amount of probiotics, greens. I’m thinking about ending the low Fodmap diet after ~3 weeks total, merging into a ~3 day fast, then rebooting very carefully with the protocol you outline here and perhaps a very low fat diet. Fasting is the **only way I’ve managed to feel normal in the past three years (it made me feel so great, so I figure that’s got to be worth something). Hopefully that will give me a platform by which to affect real change in the microbiome, if I re-feed strategically. Anyway, just sharing my journey. Thanks again

    • @gutmicrobiomequeen
      @gutmicrobiomequeen  3 ปีที่แล้ว +1

      John I'm so glad my little channel is helpful for you!
      I'm glad the low FODMAP diet helped you, but I do agree woth you that it's not a long-term solution. The key to understand is that if you are responsive to this diet you are practically guaranteed to have dysmotility (possibly bad enough to lead to SIBO), dysbiosis, or both. Working on those things while also strategically reintroducing the FODMAPs is where the magic will happen. Best of luck! 🥰

  • @empireravenshadow5
    @empireravenshadow5 ปีที่แล้ว

    awesome video, thx so much

  • @durairanganathan5059
    @durairanganathan5059 3 หลายเดือนก่อน

    Thank you for great video🎉

  • @dr.grahamsigalet277
    @dr.grahamsigalet277 2 ปีที่แล้ว +1

    These are great videos. What is your go to gut test? I've just abandoned doctors data myself.

  • @stefanrohrer3576
    @stefanrohrer3576 4 หลายเดือนก่อน

    Great Video

  • @jasodan72
    @jasodan72 2 ปีที่แล้ว +2

    Does taking charcoal slow down the intestines? It seems to in me and seems to cause my bloating but not 100% sure. I will have to give charcoal another try as i think i am getting die off from taking antimicrobials.

  • @araboy7474
    @araboy7474 3 ปีที่แล้ว +2

    Amazing! After watching this I try to connect the puzzles together. I was reading about Oxalates and why they are harmful to the body, and it is very similar to LPS when talking about the symptoms. Is this somehow connected to LPS?
    I hope you do a video about Oxalates... are they really harmful and related to gut issues?

    • @user-nt9rj8sz4m
      @user-nt9rj8sz4m 7 หลายเดือนก่อน

      Leaky gut.. the same thing

  • @szeretettvagy1666
    @szeretettvagy1666 9 หลายเดือนก่อน +1

    Thanks for the nice and clear explanation! You could be a teacher, too. 😊.
    How can LPS bacteria be detected in the blood? Is there a specific blood test for that?
    How long the coal could be taken?
    Thanks for spreading the knowledge! God bless you!

  • @hisairness28
    @hisairness28 ปีที่แล้ว +3

    High saturated fat causes LPS? Do mono or poly also cause or lower LPS? If so, which fats are best?

    • @bradleywiskowski8516
      @bradleywiskowski8516 5 หลายเดือนก่อน +3

      Sesame oil & perilla oil specifically are the safest oils to consume when LPS is high & leaky gut is present. LPS cannot ride on the fatty membranes of these oils … however … they can hop on olive oil, coconut oil, and even avocado oil and traverse throughout the body.

  • @brock013
    @brock013 3 ปีที่แล้ว

    My gut is not healing . I've tried probiotics for months it gives bad reaction fermented foods makes me worse. I have skin breakout due to lps . I had atopic dermatitis before . Is my histamine causing leaky gut?

  • @dimitrichristou4889
    @dimitrichristou4889 ปีที่แล้ว

    Could this be a *possible* cause for a high secretory IGA stool test reading? (2000)

  • @maloryhope6075
    @maloryhope6075 ปีที่แล้ว +1

    Thank you! God bless you! I have all the symptoms. And I've been trying to heal it with carnivore. Lol. Wow!

  • @junesharp8219
    @junesharp8219 2 ปีที่แล้ว +1

    amazing

  • @yvonnekiwior9633
    @yvonnekiwior9633 หลายเดือนก่อน

    Does LDL cholesterol not bind to lps and take it out of the blood system?

  • @christinasimpson6016
    @christinasimpson6016 8 หลายเดือนก่อน

    Thank You

  • @milene1388
    @milene1388 3 ปีที่แล้ว +1

    Are diatomaceous earth or bentonite clay also good to use instead of charcoal?

    • @gutmicrobiomequeen
      @gutmicrobiomequeen  3 ปีที่แล้ว +2

      Good question! I don't think either is as effective as charcoal, honestly.

  • @martamoure7372
    @martamoure7372 ปีที่แล้ว

    hoe to remove brain lps from the dienoff of bartonella in the brain .. sos trying to save my brain know how to hral.but this is flaring brain mcas and cannt do well

  • @tootsjwu29
    @tootsjwu29 ปีที่แล้ว

    will diamotaceous earth work?

  • @Seeker2400
    @Seeker2400 2 ปีที่แล้ว +1

    What about larazotide acetate

  • @GhostOfRT300
    @GhostOfRT300 4 หลายเดือนก่อน

    Brilliant

  • @randallhesse5011
    @randallhesse5011 11 หลายเดือนก่อน

    I figure it might be lipopolysaccharides (LPS) from a leaky gut that is causing my brain fog, chronic fatigue, inflammation, and feeling like cr@p. But then again it might be that my mitochondria might just need some autophagy. It may be both.

  • @jamesmcmahonii8433
    @jamesmcmahonii8433 3 หลายเดือนก่อน

    It took less than 6 months to end up in full septicemia from LPS. Not 1 doctor knew what this was.
    Glucose lightly elevated at times. It caused tissue hypoxia and massive connective tissue destruction in just 6 months. I lost my right arm, shoulder, and pec from this.

    • @jamesmcmahonii8433
      @jamesmcmahonii8433 3 หลายเดือนก่อน +1

      I was an athlete. Switched to lighter type exercises to save my joints.
      Worst decision on my life.

    • @AdamZayeed
      @AdamZayeed หลายเดือนก่อน

      Hey james I have a question. So 1. is there a lab test i can get like a leaky gut test that will show lps
      2. what diet/elimination diet should you do?

    • @jamesmcmahonii8433
      @jamesmcmahonii8433 หลายเดือนก่อน +1

      @AdamZayeed yes. You can get an LPS test through LabCorp or Quest. You can also do a stool test for it. I just did this at Sanoviv in Mexico as well as at home in the US.
      2. Elimination diet to see what you're "allergic" to. In my case, it was from Lyme and co infection treatment. Despite probiotics, my gut was still broken. Mediterranean diet is the way to go.

    • @AdamZayeed
      @AdamZayeed หลายเดือนก่อน

      @@jamesmcmahonii8433 Really really appreciate it you replying back to me? But also why am i hearing that some of the people are going low saturated fat? does it mess up with LPS? or is it something else? like going low fat is helpful? So many questions I’m sorry😂

    • @jamesmcmahonii8433
      @jamesmcmahonii8433 หลายเดือนก่อน

      @AdamZayeed saturated fat and trans fats cause gut inflammation. That allows LPS to enter the blood stream and cause an immune response. Diets low in these fats and high in fiber allow the gut to retighten.

  • @jefferadus8582
    @jefferadus8582 9 หลายเดือนก่อน

    Hi is actived charcoal also good for the toxics from Candida?

    • @user-nt9rj8sz4m
      @user-nt9rj8sz4m 7 หลายเดือนก่อน +1

      İt also binds with minerals...You can try immunoglobulins and protlytic digestive enzyme as a binder

    • @jefferadus8582
      @jefferadus8582 7 หลายเดือนก่อน

      @@user-nt9rj8sz4m thx

  • @michellet1800
    @michellet1800 4 หลายเดือนก่อน

    What about gluten!?

    • @Itzbrady_
      @Itzbrady_ 4 หลายเดือนก่อน

      Gluten affects less than 1% of the population, I don't think it's the pasta I think it's the saturated animal fats in the blood that is causing the endotoxemia

  • @MindChonticha
    @MindChonticha ปีที่แล้ว

    Excuse me. Do you know how to treat this disease?

  • @bobdylan9117
    @bobdylan9117 3 ปีที่แล้ว +1

    good topic

  • @bobdylan9117
    @bobdylan9117 3 ปีที่แล้ว +2

    someone with a blue car down-voted this video.