Im struggling in Biochem..😭.This is a life saver. Had to look for so many videos to finally find someone who makes this make sense. You guys are gifted teachers!! God bless you!!!
A little mistake, if I may. In galactose-1-phosphate uridyl transferase, the galactokinase enzyme is actually active and functioning normally leading to accumulation of galactodse-1-phosphate in the hepatocytes leading to hepatomegaly.
Just a quick correction: Galactokinase creates GALACTOSE-1-phosphate, not galactokinase-1-phosphate. You have this right in the diagram, but incorrect in the slide showing the presentation of galactokinase deficiency. The next enzyme is also called galactose-1-phosphate uridyltransferase (GALT), NOT galactoKINASE-1-phosphate uridyltransferase.
How does galactosemia cause diarrhea?i mean what is the mechanism? Isn't Galactose normally absorbed into the blood circulation so this rules out the osmotic diarrhoea?
What is the role of lactose in biology? Why doesn't milk contain straight glucose that already exists in the blood and doesn't have to go through these steps and risks?
First, thank you for your efforts but I still don't get why Classic Galactosemia is more severe. 😬 How is the accumulated volume more than the case with Galactokinase def. ?
Becase phosphorylated molecules trapped inside the cells... therefore body phosphate levels go down(energy depletion,affects other metabolic pathways due lack of free phosphates) as well as galactose-1-phosphate accumulate in liver causing hepatomegaly which could cause liver dysfunction later on...
Typo’s:
Galactose-1-Phosphate Uridyltransferase
Galactose-1-Phosphate
(Drop the galactoKINASE typo)
DirtyUSMLE thank you so much for your videos ... love them
My deep appreciation for the wonderful efforts.
My exam after 2 days any advices???
@@MohamedAli-bk6vk howd it go?
Im struggling in Biochem..😭.This is a life saver. Had to look for so many videos to finally find someone who makes this make sense. You guys are gifted teachers!! God bless you!!!
I have a test tomorrow and I have been searching for videos that will make everything make sense and I just did 😂😂💃💃
A remarkable tutor ....not a dirty medicine it is awesome and beautiful medicine 💊 😍 ✨ 💕 ❤
Clear clear clear , I have finished with my lectures notes, and with those videos biochemistry will be more easier for me , thank you very much
A little mistake, if I may. In galactose-1-phosphate uridyl transferase, the galactokinase enzyme is actually active and functioning normally leading to accumulation of galactodse-1-phosphate in the hepatocytes leading to hepatomegaly.
I was thinking same
Thanks!
You are an amazing teacher. Thank you for helping so much!. It is a beautiful Medicine.
You are the best, your videos are really helpful
I would like to make request if you could make some videos on microbiology also ... it’s quite difficult to remember all those organisms
use sketchy micro
.
It is the best video in biochemistry I have ever seen .... well done 😍💛💚
This was amazing, thank you so much!
Could you please make a video about HEME ? Thanks !! Your videos are amazing! And the way you explain things are unique!
Thanks. Great video. Concise and clean.
Just love your videos so much!! It give me confidence and motivation to keep studying biochemistry ❤️🔥
just wow, great video
Great 👍
Actually mad helpful
You the real hero!
Just a quick correction: Galactokinase creates GALACTOSE-1-phosphate, not galactokinase-1-phosphate. You have this right in the diagram, but incorrect in the slide showing the presentation of galactokinase deficiency. The next enzyme is also called galactose-1-phosphate uridyltransferase (GALT), NOT galactoKINASE-1-phosphate uridyltransferase.
Yup these are typos
Love love loveee this video thank you sm
Thank you soo much
I love your videos 🎃🎃
I love this guy
The milk u are talking about is cow milk or human milk?
Incredible
is there rate-limiting enzyme for galactose metabolism?
Can't you get lactose intolerance post-Giardia?
How does galactosemia cause diarrhea?i mean what is the mechanism? Isn't Galactose normally absorbed into the blood circulation so this rules out the osmotic diarrhoea?
What product is formed as a result of methylation of galactose?
What is the role of lactose in biology? Why doesn't milk contain straight glucose that already exists in the blood and doesn't have to go through these steps and risks?
suuuperb !!!
Hello, can you please help me understand how adults with galactosemia are more tolerant when taking galactose-containing products? :(
would only make sense if they had a lactase deficiency/lactose intolerance, not due to insufficient galactose kinase or G1P-uridyltransferase.
what is NVD after milk? @10.08
Nausea, vomiting, diarrhea
Classic Galactosemia is more severe because PO4 3- is depleted.
thnx ❤❤❤❤
First, thank you for your efforts but I still don't get why Classic Galactosemia is more severe. 😬 How is the accumulated volume more than the case with Galactokinase def. ?
Becase phosphorylated molecules trapped inside the cells... therefore body phosphate levels go down(energy depletion,affects other metabolic pathways due lack of free phosphates) as well as galactose-1-phosphate accumulate in liver causing hepatomegaly which could cause liver dysfunction later on...
Shera Wijesinha Thank you!!!
Transferase لانه بمرحلة انتقالية 🤱🤱🤱🤱
❤❤❤❤❤❤
❤❤❤
High yeald this, low yeald that. Are you studying to pass an exam, or to learn a subject?
You can’t learn what you need to learn without first passing the exam. That’s the backwards medical education system in the US
I have this, in case you wanna know how terrible things will get once you hit 50
❤❤❤
Thank u so much