Hi, thank you so much for this video! I just have a question that I can't seem to answer: why can't the lagging strand synthesise continuously toward the helicase on the left of the bubble?
And dsDNA are antiparallel and when there is a 5"end in the strand in one place, the related other place on the other strand there is 3" end. This is the reason for synthesis of leading and lagging strand
Sure! The "origin of replication" is where the polymerase enzyme starts laying down new strand. It goes off in the 5'-3' direction to make the lagging strand, but *behind* the origin of replication, that's where the lagging strand gets laid down as the replication fork goes on unwinding the double helix. :-)
Brilliant! 5 videos later this explains the process in the clearest format!
Brilliant video sir ... Thank you so much
For explaining this concept in the least simpler way✨✨✨
This video is great except for the fact that DNA polymerase moves from 3 to 5 continuously on the leading strand not from 5 to 3
Hi, thank you so much for this video! I just have a question that I can't seem to answer: why can't the lagging strand synthesise continuously toward the helicase on the left of the bubble?
Because only 5" to 3" DNA polymerase synthesis new DNA strand.
And dsDNA are antiparallel and when there is a 5"end in the strand in one place, the related other place on the other strand there is 3" end. This is the reason for synthesis of leading and lagging strand
Loved your explanation
Thank you!
Thank you!!!
Thank you so much❤️
Thank you so much
Great explanation. Thank you!
Excellent video. This helped me a lot. Thank you so much! Liked.
this is perfect thank you!!
Great video!
Well explained 🙌
Thank you so much sir
Amazing!
Thanks alot Sir 💕
amazing ...5 seconds on video ....and i subscribed .....☺☺☺☺☺☺☺
Thank you. Helped alot. :)
primers???
Can’t the leading strand become lagging the opposite way on the right
Sure! The "origin of replication" is where the polymerase enzyme starts laying down new strand. It goes off in the 5'-3' direction to make the lagging strand, but *behind* the origin of replication, that's where the lagging strand gets laid down as the replication fork goes on unwinding the double helix. :-)
good job
thanks a lot understood now
Thank you!