This Protein Hugs Ice Crystals to Death

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  • เผยแพร่เมื่อ 17 ก.พ. 2021
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    If liquid water is an absolute requirement for life--how on earth does ANYTHING survive in Earth's polar regions? What should be a frozen wasteland is a thriving ecosystem. Let's look at ice structuring proteins and discover how they literally bind to ice crystals as they form--giving the smallest arctic critters a fighting chance.
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ความคิดเห็น • 85

  • @sriramramesh5318
    @sriramramesh5318 3 ปีที่แล้ว +74

    It's weird thinking of how the hydrophobic side of these proteins are probably making the proteins spin around nonstop whenever the temperature is anywhere above freezing

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +34

      It could be that they aren't made until an organism hits a certain temperature too. Lots of factors here the research is still figuring out!

    • @zlodevil426
      @zlodevil426 8 วันที่ผ่านมา +21

      There could be quintillions of molecules in your body right now that just spin and don’t do anything else

    • @ALTERRAa8
      @ALTERRAa8 6 วันที่ผ่านมา

      ​@@zlodevil426 reletable

    • @casualbird7671
      @casualbird7671 4 วันที่ผ่านมา +4

      ​@@zlodevil426 Like the compliment system~

    • @Antleredangelbun
      @Antleredangelbun 3 วันที่ผ่านมา

      My brain's reward system lol​@@zlodevil426

  • @thegoodlydragon7452
    @thegoodlydragon7452 3 ปีที่แล้ว +52

    "Kill it to death." lol

  • @IncidentallyHuman
    @IncidentallyHuman 3 ปีที่แล้ว +66

    Hopefully this channel blows up in popularity. It deserves it.

    • @petervansan1054
      @petervansan1054 8 หลายเดือนก่อน +4

      shame it died :(

    • @taoafro1740
      @taoafro1740 5 วันที่ผ่านมา

      I agree. ✌🏾❤️

    • @1337bitcoin
      @1337bitcoin 4 วันที่ผ่านมา

      2024 finally getting the recognition this channel deserves

  • @kalmanchrister1027
    @kalmanchrister1027 3 ปีที่แล้ว +23

    Another interesting protein is kind of the reverse of this one: ice nucleating proteins. They seem to help form ice crystals by providing a kind of optimal scaffolding for water molecules, so that they will bind together.
    They may have a role in ice nucleation in clouds, and by extension, formation of rain and global water cycles!

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +10

      Welp. I didn't have a _lot_ of time for a research hole--but here we are!

    • @bladdnun3016
      @bladdnun3016 2 วันที่ผ่านมา +4

      How do the nucleating proteins get into a cloud? And why would an organism want ice to form? To use the enthalpy of fusion to keep warm?

    • @Avaney69005
      @Avaney69005 วันที่ผ่านมา

      Your video is good​@@Clockworkbio

    • @john-ic5pz
      @john-ic5pz 3 ชั่วโมงที่ผ่านมา +1

      @bladdnun3016 ikr. I call b.s. on this.
      atmospheric dust isn't an effective nucleation site?

  • @CanOSpamX
    @CanOSpamX 3 ปีที่แล้ว +18

    Great video! I've seen tons of videos here on TH-cam talking about how "fish have antifreeze in their blood" but as far as I know no one has actually talked about how that really works and boy is it fascinating. This channel makes we wish I took more bioscience courses. :)

  • @mmcharchuta
    @mmcharchuta 3 ปีที่แล้ว +12

    Your graphics are amazing and your loose style makes the learning process all the more fun.
    I feel like i'm listening to a friend :D

  • @adityasingh-yz7tr
    @adityasingh-yz7tr 6 วันที่ผ่านมา +4

    Absolutely great video . i hope the algorithm gives you the reach you deserve even if it's 3 year late

  • @noel.gonsalves
    @noel.gonsalves 3 ปีที่แล้ว +16

    This legitimately blew my mind. I did not see that coming.

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +5

      Biochem is so nuts, right?

    • @noel.gonsalves
      @noel.gonsalves 3 ปีที่แล้ว +1

      @@Clockworkbio indeed it is

  • @arrowinmygluteusmaximus
    @arrowinmygluteusmaximus 3 ปีที่แล้ว +9

    but wouldn't this just delay ice forming not lower the temperature required to freeze? as long as there is liquid water below the freezing point a new nucleation point can start right? or do these structures also slowly melt the ice they surround?

    • @Lacksi12
      @Lacksi12 3 ปีที่แล้ว +1

      Came here to ask exactly this aswell. If anyone knows the answer Im interested to hear it!

    • @AaronQuitta
      @AaronQuitta 3 ปีที่แล้ว

      Maybe its the temperature foe an entire body of water to freeze?

    • @silverharloe
      @silverharloe 3 ปีที่แล้ว +13

      they delay ice forming, as you say. and then water starts to crystalize somewhere else and gets delayed... and after a few iterations of that, you're delaying it so much that it's not freezing. but if you go colder, then the crystallization goes faster than the delays -- that colder point is the new(lower) freezing temperature.
      freezing is an average - you take a quintillion water molecules which are all jiggling around and slow a bunch of them down and that's what colder water means - less jiggling overall, but the jiggling hasn't stopped. keep slowing a bunch down (i.e. lower the temperature) and eventually some are so slow they start to hang together more than they jiggle apart. but they are still being jostled by nearby jiggling molecules, pushing them apart as they try to hang together. bits of ice are forming and breaking constantly as the temperature lowers - delaying the formation of crystals is the same as lowering the freezing point, because you need the crystals to start forming faster than they are being broken by nearby jiggling water molecules -- which is to say you need to slow down the nearby water molecules (also known as lowering the temperature) so they are more likely to join in the crystal than to knock it apart. I need some of this guy's animation skills, but hopefully you get the idea anyway.

    • @silverharloe
      @silverharloe 3 ปีที่แล้ว +5

      Now I'm envisioning a dance club full of people all bumping into each other as they dance - and some people try to slow dance, but with all the bumping they keep getting bumped apart. some people get tired and start dancing slower, but there's not a DJ that tells everyone to stop and find a partner all at the same time. because the DJ isn't there to tell everyone to be cold all at once, it takes a long time for everyone to get tired enough that more and more slow dances can come together without being bumped apart.
      in addition to what I said about freezing being an average - the other important thing is that freezing is the default state. the water doesn't GET slowed down, it's slowing down all on it own. "making it colder" is a process of "adding less and less heat" and letting the heat it bleed off. but absolute zero is very difficult to achieve - so you're never really adding zero heat, just less heat. you can add so little that you aren't making up for heat that is going away - we call that the freezing point, but you still need some time to let all the heat drain out for it to actually finish freezing.
      I'm trying here, but even "freezing water" is complicated stuff. Sorry if I'm not properly explaining it.

  • @brianrubin2069
    @brianrubin2069 3 ปีที่แล้ว +5

    "kill it to death" the most scientific of terms. Great video! Hope more people start watching you soon! Also did your website go down where you had the more in-depth explanations?

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว

      Yea I had to shutter the in-depth explanations for now! When you're a small youtuber--the budget is real tight. I decided to crowdsource the details/ disucssion on my twitter (@this_clockwork) and use the website budget to fact check my bigger scripts for now. This one didn't make the cut for fact checking since I needed that whole budget to make sure I nail the facts for my March video. There are some really interesting wrinkles in what make these proteins work tho!

    • @brianrubin2069
      @brianrubin2069 3 ปีที่แล้ว

      @@Clockworkbio Makes sense! Good luck with production!

  • @ItsGray3
    @ItsGray3 6 วันที่ผ่านมา

    This channel has such amazing videos and deserves way more attention than it currently has!

  • @this_1_dude_named_iggy654
    @this_1_dude_named_iggy654 3 วันที่ผ่านมา

    How am i not gonna immediately click this video with information as cool as this

  • @jujjuj7676
    @jujjuj7676 14 วันที่ผ่านมา +1

    Make more please!!! More biochem!!!😊😊😊😊

  • @cassidyhawk420
    @cassidyhawk420 3 ปีที่แล้ว +3

    Marine biology student here, great video!

  • @Unraveled
    @Unraveled 3 ปีที่แล้ว +15

    Someone stole my "hexagons are the bestagons" comment so now I don't know what to say...

  • @AaronQuitta
    @AaronQuitta 3 ปีที่แล้ว +1

    Crazy, amazing, I love this! Thanks for the great video.

  • @LFTRnow
    @LFTRnow 12 ชั่วโมงที่ผ่านมา

    This is not my specialty but as an engineer, i love these vids. You can just watch the chemistry and mechanical features in action, and in fairly short vids too!

  • @arrowinmygluteusmaximus
    @arrowinmygluteusmaximus 3 ปีที่แล้ว +7

    any tips for a fellow creator? you seem to be able to crank these videos out at an incredible pace, even though they are so heavily edited and high quality while simultaneously being so small (in number of subscribers) that I'm assuming you don't do this full time.

    • @Unraveled
      @Unraveled 3 ปีที่แล้ว +2

      He's awesome like that

    • @AntonWongVideo
      @AntonWongVideo 3 ปีที่แล้ว +1

      I'm guessing planning and scheduling helps a lot with that!

  • @somethingsafoot
    @somethingsafoot 3 ปีที่แล้ว +4

    biocord represent great video

  • @rosemarychadi7734
    @rosemarychadi7734 3 ปีที่แล้ว +2

    Great video! we really enjoyed it

  • @Lars_Maassen
    @Lars_Maassen 3 ปีที่แล้ว +3

    3:09 Hexagon is bestagon

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +1

      It really is! And there're EVERYWHERE in biochem and Organic Chemistry!

  • @bioZone101
    @bioZone101 3 ปีที่แล้ว +3

    getting hugged to death ain't sounding half bad anymore

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +2

      I mean, of all the ways to go, right?

  • @Information_Seeker
    @Information_Seeker 6 วันที่ผ่านมา +1

    so cryosleep is back on the table?

  • @jesusvalencia5520
    @jesusvalencia5520 หลายเดือนก่อน

    Great video!! I have a question. I read that inside the Beta sheets, the Threonine aminoacid was the one binding to the ice crystals. Maybe a different protein in the same family?

  • @justenkem5514
    @justenkem5514 ปีที่แล้ว +1

    "Your test results came back aladine" "is that aladine or aladine" "it is aladine" 😅😳🥺😅🥺

  • @brahimbest1
    @brahimbest1 3 ปีที่แล้ว +2

    Really, that blows my mind!

  • @defeatSpace
    @defeatSpace 2 ชั่วโมงที่ผ่านมา

    Phenomenal videos 😁

  • @quantumview8151
    @quantumview8151 9 วันที่ผ่านมา

    What happens then. Wouldnt enough clumps eventually take over enough area that the cell cant function, or do they expell it or destroy it in some way?

  • @xavierestelles9327
    @xavierestelles9327 3 ปีที่แล้ว +1

    This is FASCINATING

  • @pimbel8830
    @pimbel8830 11 วันที่ผ่านมา

    This video isn't part of any playlist so it will be kinda hard to find

  • @agnosticmuslim6341
    @agnosticmuslim6341 11 วันที่ผ่านมา

    Loveee Biochem when taught like this

  • @AntonWongVideo
    @AntonWongVideo 3 ปีที่แล้ว +1

    1:16 plankton are VERY important for the food chain...just not for the Krusty Krab
    Also, I'm digging this "stop motion" mograph animation style! How many times did you use "wiggle" expressions in After Effects?

  • @Alexadria205
    @Alexadria205 8 วันที่ผ่านมา

    I can see crops being genetically engineered to produce these proteins to create frost resistant crops!

  • @MrAngelos006
    @MrAngelos006 3 ปีที่แล้ว

    first video and I'm amazed

    • @MrAngelos006
      @MrAngelos006 3 ปีที่แล้ว

      gonna watch and like all your videos

  • @beastypie99
    @beastypie99 3 ปีที่แล้ว +1

    Very cool!

  • @lauradftba4653
    @lauradftba4653 3 ปีที่แล้ว +1

    This is so cool!!!!

  • @sethsoarenson7414
    @sethsoarenson7414 3 ปีที่แล้ว

    Texans: WRITE THAT DOWN! WRITE THAT DOWN!

  • @noekiyu
    @noekiyu 2 ปีที่แล้ว +1

    You really sound like Jim Parsons from the Big Bang Theory.

  • @zeroTorsion
    @zeroTorsion 2 วันที่ผ่านมา

    love it

  • @realkekz
    @realkekz 8 วันที่ผ่านมา

    Please come back

    • @Clockworkbio
      @Clockworkbio  7 วันที่ผ่านมา +1

      ONE MORE MONTH

    • @realkekz
      @realkekz 7 วันที่ผ่านมา

      @@Clockworkbio :) I found this channel at the exact right time!

  • @KitsuAwA
    @KitsuAwA วันที่ผ่านมา

    Dumb instrusive thought,could a human consume this to last longer in cold envs

  • @vinniepeterss
    @vinniepeterss 21 ชั่วโมงที่ผ่านมา

    ❤❤

  • @particleonazock2246
    @particleonazock2246 2 ปีที่แล้ว

    Meanie protein

  • @jabu5427
    @jabu5427 3 ปีที่แล้ว

    Water life

    • @Clockworkbio
      @Clockworkbio  3 ปีที่แล้ว +2

      and a little sunlight and some air and a couple minerals!

  • @matteomezzetti8277
    @matteomezzetti8277 10 วันที่ผ่านมา

    I love this channel but its dead😢

  • @sheldondrake8935
    @sheldondrake8935 8 วันที่ผ่านมา

    great content, should have a ton more subs...but the vocal fry is unbearable...

  • @3glitch9
    @3glitch9 วันที่ผ่านมา

    Stay squishy my friends...

    • @Clockworkbio
      @Clockworkbio  วันที่ผ่านมา +1

      brb stealing this line

  • @michaelshea4834
    @michaelshea4834 ปีที่แล้ว +1

    I’ve always been annoyed by people who ascribe intelligence to an inanimate (evolution) process. It’s an argument for God.

  • @ekbergiw
    @ekbergiw ปีที่แล้ว

    2:48 shout-out to @viheart

  • @john-ic5pz
    @john-ic5pz 3 ชั่วโมงที่ผ่านมา

    wth...I've never heard alanine pronounced that way
    is glycine /gly - sine/ too?