Building Life Block by Block (Protein by Protein) | Fundamental Concepts

Assistant Professor of Biology Gustavo Silva discusses protein diversity as well as how the structure and function of protein can control life as we know it.
This video is part of Duke University's Fundamental Concepts series. Each episode features a Duke faculty member explaining an entire concept from beginning to end in roughly 10 minutes.
𝐅𝐮𝐧𝐝𝐚𝐦𝐞𝐧𝐭𝐚𝐥 𝐂𝐨𝐧𝐜𝐞𝐩𝐭𝐬 | #𝐁𝐢𝐨𝐥𝐨𝐠𝐲
WHY BIOLOGY MATTERS ft. Steve Nowicki ► duke.is/uRqwCv
PRIMATE EVOLUTION ft. Jenny Tung ► duke.is/CCIETr
A BRIEF HISTORY OF US ft. Herman Pontzer ► duke.is/TuiTF7
CONSERVATION BIOLOGY ft. Anne Yoder ► duke.is/KdLygf
ECOLOGY ft. Jean Philippe Gibert ► duke.is/HUpviJ
WHY STUDY PLANTS ft. Philip Benfey ► duke.is/nyuVsN
𝐆𝐮𝐬𝐭𝐚𝐯𝐨 𝐒𝐢𝐥𝐯𝐚
𝘈𝘴𝘴𝘪𝘴𝘵𝘢𝘯𝘵 𝘗𝘳𝘰𝘧𝘦𝘴𝘴𝘰𝘳 𝘰𝘧 𝘉𝘪𝘰𝘭𝘰𝘨𝘺
Gustavo Silva's main research goal is to understand and be able to control how cells respond to stressful and harmful conditions, which are the underlying causes of many human diseases. To achieve this goal, he studies cellular response to stress at the protein level and aims to characterize the different regulatory functions mediated by the ubiquitin-proteasome system (UPS), essential machinery involved in modulating protein dynamics. Ultimately, regulating specific UPS roles will provide new tools to increase cellular tolerance to a variety of environmental stresses, which is highly relevant for a variety of degenerative diseases. The main focus of Silva's lab is to investigate the unprecedented regulation of translation mediated by ubiquitin. His lab continues to push the field forward and to use a combination of proteomics, genomics, and molecular methods to understand the mechanisms by which ubiquitin regulates translation, and ultimately, cellular response to stress.
𝐀𝐛𝐨𝐮𝐭 𝐃𝐮𝐤𝐞 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
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𝐅𝐨𝐥𝐥𝐨𝐰 #𝐃𝐮𝐤𝐞𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
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[@veronicajay2788]

You're a great teacher! Thank you for explaining this concept so well in terms that are easy to understand. Beautiful!

[@Amanda-ho3hg]

The concept with the beads finally helped me picture how proteins fold! That was a wonderful way to teach that idea. Thank you so much for sharing!

[@dukeuniversity]

Wonderful!

[@alonzojohnson7955]

😎