I just wish I had a longer lifetime (I just turned 80) because I am always discovering new things I would like to know something about, and the above subject is another! I had never heard of what she is talking about. So I was glad to find out there's a book that will try to enlighten what the lecturer was talking about.
The most boring presentation. Boring verbal diarrhea and the poor woman is totally confused as to the meaning of Epigenetic. What saves her is the cute accent. She is trully the product of Rockefeller education system. Sad.
@@gracegwozdz8185. Well that’s a rather pretentious comment, given that she is an expert in epigenetics. Perhaps you would care to enlighten us with your wisdom on where she went wrong?
I'm here after reading her book "The Epigenetics Revolution" to learn about possible updates in the field since it came out a few years ago. I would highly suggest the book to anyone as I had no background knowledge other than high school Biology and yet every chapter would blow me away.
I absolutely have to watch this again and again. She has few equals in terms of clarity and lucidity. I am going to forward this to my entire family. One of the most interesting topics explained by one of the best presenters.
I'm currently reading 'Junk DNA' and I can assure you that it is really informative and it doesn't bore you. As a first-year medical college student, it is really helpful to visualize the epigenetic differentiation. Examples she gives are hilarious.
The 8 proteins are histones and form a protein complex known as a histone octamer, which is spool shaped (marshmallows were used in the demonstration). The 8 proteins in the histone octamer are actually 2 copies of 4 proteins, H2A, H2B, H3 and H4. DNA wraps around the histone octamer known as a nucleosome and they form chains like beads on a string making up chromatin. A nucleosome can be defined as a small length of DNA wrapped around eight histone proteins. The key difference between chromatin and nucleosome is that chromatin is a whole structure of complex DNA and proteins while nucleosome is a basic unit of chromatin. The beads on a string make up something called euchromatin or open chromatin that is enriched in genes and active under transcription (transfer of genetic instructions) which is why it is so important in epigenetics and changes in the phenotype (physical traits- e.g. appearance).
Reading her book now after watching this a few months ago! Brilliant and exciting literature! Epigenetics is such a fascinating field! This is telling us how we can affect our future progeny!
Yes - but we need the right stimulus; and that can come only from the WORD of GOD, found in the Bible. We could easily deteriorate into barbarism, especially if we start copying animals, instead of reminding ourselves that we are made in the image of GOD.
I scored rotten childhood, alcoholism, diabetes, 40yrs depression. My parents died 2012. I went outside and stood in the sun. Instant relief then happiness. Counselling and diagnosed as having aspergers (3yrs old emotionally top 2% computational brain). I took up Zentangling Art and I am still changing & growing. It took 20 yrs after MtDna test for me to find a living relative and I discovered that 5 gens back my ancestor came from Sweden who was a Sami. I then discovered I had inherited characteristics from that cultures but not in the same configuration. I bought a good copy of the I Ching and asked HOW I could bring information from the MtDna into my conciousness. The answer was hexagram 19. It told me not to think about it or ask another question and when I asked another question I was told to not do that again. This is simplified. The overall answer was that the answer was approaching. Sooooo... I bought a book on epigenetics, wrote to a scientist and I find your teaching style that puts the text books I am reading into context. I am 72 and am like a teenager. THANK you so much.
How fortunate that I in india can access this extraordinary lecture delivered so well and generously sprinkled with humor. Great contribution to science education. Have her books which are so precious for me
Its all actually very simple to understand when you grasp what is actually occurring in terms of epigentics and how we are products of evolution - genetics and events - what we do and what is done to us
Finally! we have an exciting, summation of information about this field! Thank you for posting. Best explanations, clear analogies and diagrams I've ever found .I've been interested in this field for many years, though no longer a formal student. This great video brings me up to date.
Nice. But molecular genetics was already about gene expression regulation, in bacteria, at the start. Sex is a molecular dialog and it has probably many and variate levels of (self) interpretation. I have discovered computer science in the working of the DNA of Escherichia Coli, a long time ago (Jacob & Monod mainly).
🪄✨ Made with SummarizeYT 0:49 - The human genome sequence was first released in 2001, causing a huge hoopla. 2:03 - Epigenetic phenomena have been known for a long time but were not given much attention. 3:00 - Laboratory mice with the same genetic background can have different weights due to epigenetic factors. 5:01 - Gender in crocodiles is determined by the temperature at which the eggs develop, not genetics. 6:01 - Different cell types in our body have the same DNA code but exhibit different characteristics. 8:08 - Epigenetics plays a crucial role in gene expression and can be influenced by external factors. 12:00 - Epigenetic modifications can switch genes on and off, leading to different gene expressions. 14:00 - Epigenetic modifications can be compared to different flavors of jelly tots, introducing flexibility in gene expression. 16:15 - Epigenetic modifications can also compact DNA, permanently switching off gene expression. 17:27 - Epigenetic modifications can go wrong and contribute to diseases like cancer and diabetes. 19:01 - Children who have experienced abuse or trauma in their childhood are more likely to develop chronic diseases later in life. 20:07 - Epigenetics can influence what happens in organisms without altering the DNA sequence. 20:42 - Baby rats that are loved and cared for by their mothers have low levels of stress hormones. 22:03 - Epigenetic modifications in rats can be passed down from generation to generation. 24:01 - Epigenetic information is necessary for mammalian reproduction. 26:41 - Epigenetic changes can result in significant differences in physical characteristics, as seen in agouti mice. 30:03 - Mice can learn to associate a smell with something negative, and this fear response can be passed on to their offspring. 31:43 - Lamarck's theory of acquired characteristics is not entirely accurate, but epigenetic changes can be influenced by the environment. 34:01 - Trauma experienced by male mice can be passed on to their offspring. 35:05 - Epigenetic changes can affect the offspring's physical characteristics, as seen in the experiment with female mice. 36:03 - Identical twins can have different outcomes due to epigenetic changes.
First time i am watching her. Today I purchased her book " The Epigenetics Revolution. Not my subject. But i have interest. Happy to watch. Thank you Madam. Regards
If for whatever reason molecular biology doesn't work out for Nessa Carey, she can surely do well as a stand-up comedian! Very entertaining and enlightening talk!
What a wonderful (and delicious!) lecture! I am enraptured by her humour and her passion. What a shame I am watching this 9 years after the release of the original video.
Great video! Increasingly our behavior determines our longevity. Just as weight scales provide transparency and motivate dieting, epigenetic tests now make biological age (as distinct from chronological age) more transparent and motivate us to adopt right behaviors to help us live longer.
Her explanation about stress and childhood experiences is interesting. I was very fortunate because I had a pretty stable, happy childhood with a protective father who thought I was a piece of gold and a loving mother who was a great nurturer. Even though I was overweight and constantly bullied, I retained my happiness and confidence that has allowed me to be successful in my career and personal life. I am married to a great person, but have noticed that he is usually depressed and insecure. His sister has finally admitted that out of 6 siblings, he was given the least amount of attention and praise and was often criticized. This was needed information for me as his spouse because I can now understand why he rather that I remain overweight. When I lost most of my weight, my husband would exhibit jealousy and insecurity. He would retreat into his den, and not talk to me. Now that I have lost my mobility, my husband seems happy which I find hurtful, but with theory, I have learned that he feels empowered because he feels no one will find me attractive and he can now be the only person I can depend
Fascinating subject, i'd never heard of this subject before. Props to the lecturer for giving such an entertaining lecture on a complicated subject! I hope you have her back again.
The DNA code starts from the same then the coding changes but the DNA coding is all the same in the start of the code. Example is like computer coding. Code DNAMOMDAD then add on EYESLASHES or DNADADMOM Liver etc etc. It's so damn AMAZING
I wonder how many people who watched this wished their jobs required them to play with candy in order to do it effectively? I think a lot of companies wouldn't be so stuffy if they allowed their workers to play with candy sometimes...
Would a babies/child’s dna receptors be affected/changed by a traumatic birth experience? Ie would a more ‘relaxed’, non stressfull/traumatic birth experience have a better outcome for a child later in Life?
so the dna is still the same, just the little "jelly" dots that attach to the dna that a person might develop while interacting with his environment? But what's the mechanism behind the epigenetic changes (my guess it's still the DNA that gives instructions to the protein to make the epigenetic changes)...I mean could epigenetic changes lead to the eventual creation of a new species? Thinking more ahead, how much can we augment our body through tweaking the expression of various genes, like would we be able to grow a new arm through epigenetics, or is that sort of mutation still dependent on the manipulation of DNA? You say that the little "jelly" dots, sorry I forget the exact term you used for those molecules, attach to the genes and affect their individual expression, but how many genes do we have, what are each gene's functionalities, how does each gene interact with each other, and what explains the difference between us and a chimp or a bird or something? God damn it get more research done lady! My back is hurting from watching all these Royal Institute videos laying on my bed at 1AM in California, and I also don't have a car to go to work tomorrow morning, and I think it'd be really nice if DNA technology can allow me to grow a pair of wings! (though the image might be a bit grotesque) so I can fly around to work and buy groceries or something...
All I want to do right now is eat strawberry laces and jelly tots.....on a serious note, this lecture was FASCINATING - thank you Nessa for your fabulous energy teaching this
Oh no! Your exposure to the video (environmental factor) has changed your mental content, which could change your behaviour which could change your epigenetics, which could change the future of your offspring? Good grief this rabbit hole goes deep...
There's one thing I am confused about. So if the histones are wrapped around our genes, and say you become a smoker (but no one in your family tree extending hundreds of years smoked) and the chemical tag is added to the histones to make that gene become 'expressed', does that mean that the 'smoker gene' is predetermined? In other words, will I have a 'smoking gene' by default that is turned off, but will only be turned on if I smoke?
In all biology textbooks, Galapagos finches are mentioned as a prime example of evolution. However, a relatively recent study conducted by Peter and Rose-Marie Grant documents that the changes in beak size and shape of these birds that Darwin observed do not take millions of years, but change continuously at a rapid rate of as little as two years and that the changes are reversible. It is very likely that it is epigenetic adaptation, not evolution in the Darwinian sense. This certainly also applies in many other cases where adaptation is interpreted as macroevolution today. The theory of evolution must and will be rewritten.
Unfortunately she was not able to explain how homeostasis knows which genes to turn on and off. Or how a certain chemical affects certain genes and not others. Are certain aspects of evolution Lemarkian? Evolution takes place because of needs and choices? Do epigenetic changes eventually lead to sequence changes?
I would love to know the other side of the experiment, where mice with caring mothers were put with not so caring mothers and then had a traumatized life. What happens when a mice with a not so caring mother is put with a caring mother? They get better? They get "normal"? They don't get better? I don't know where to ask this question :( If someone could give me a clue, i would be very grateful.
How would you explain a Monarch Butterfly’s migration from central Mexico to Canada and back to the same tree? There are four generations in a year. The migration is a year long. The returning butterfly is the great grandchild of the one that left the overwintering tree. How is the information passed on through the generations?
Fantastic, Love the energy your brought to your book The Epigenetics Revolution" I wonder if you can see the link between Epigenetics and Buddhist Karma. (They are both very deep matters) Any Buddhist's out there pls read this and think....
Dear Royal institution. There are educational providers online who are of the opinion that interrupting their productions with advertisements is counterproductive. Is the income from ads really essential? One really has to wonder how you managed back in Faradays time. Perhaps you could precede broadcasts with a short statement asking for support. Tell your audience that it enables ad free content. You might be surprised at the uptick in donations received as a result. Just a suggestion, your content is greatly appreciated but the interruptions do spoil it.
Wow, really enjoyed this lecture. Any sociological/psychological applications or assumptions linked to these findings? ie, poverty, oppression, consistent trauma etc...
How do you determine if a characteristic is truly determined epigenetically or if there is some other factor, like the chemicals given off by gut bacteria, or some changes triggered by viruses, or some other mechanism I can't think of just now?
Great video! I can imagine that practical living advice can come from epigenetics, like how i can change my own in a positive way. Any chance to get that?
Hmm, for example if you don't smoke, your epigenetics for requesting more nicotin don't get switched on and your kids probably won't smoke either. Does this answer your question?
I never understood this: If you block a gene from being expressed, what gene is expressed in it's place? Wouldn't it be a wrong one, for example heart cell instead of skin cell? Is there an alternative healthier gene? It can't be nothing. If i have, let's say, a mutated finger and i block that gene off, what would be in it's place? I think is absurd that there would be no finger.
She is an amazing educator. I am grateful to be able to access high quality lecture like this for free.
I just wish I had a longer lifetime (I just turned 80) because I am always discovering new things I would like to know something about, and the above subject is another! I had never heard of what she is talking about. So I was glad to find out there's a book that will try to enlighten what the lecturer was talking about.
I'm 83...almost-feel like u🎉
This has to be one of the most interesting presentations I've seen in a while. Absolutely fascinating.
The most boring presentation. Boring verbal diarrhea and the poor woman is totally confused as to the meaning of Epigenetic. What saves her is the cute accent. She is trully the product of Rockefeller education system. Sad.
@@gracegwozdz8185. Well that’s a rather pretentious comment, given that she is an expert in epigenetics. Perhaps you would care to enlighten us with your wisdom on where she went wrong?
@@Pseudify david it seems worthless showing any sort of interest in these comments since it only demonstrates her mindset..or rather choice of one.
I'm here after reading her book "The Epigenetics Revolution" to learn about possible updates in the field since it came out a few years ago. I would highly suggest the book to anyone as I had no background knowledge other than high school Biology and yet every chapter would blow me away.
Imagine the world we'd craft for ourselves if all science was communicated so brilliantly and unpretentiously. Bravo.
Daniel Holley agreed
Daniel Holley 🍷. Drink to that.
Imagine the world ww'd craft for ourselves, if we just understood that our physical reality is a collective subjection/egregore structure
The problem is that not enough people are hearing it. The communicator is not the problem
I absolutely have to watch this again and again. She has few equals in terms of clarity and lucidity. I am going to forward this to my entire family. One of the most interesting topics explained by one of the best presenters.
Amazing lecture! She takes complicated information and breaks it down into interesting info using jokes, history, stories, movies and more! Brilliant!
I'm currently reading 'Junk DNA' and I can assure you that it is really informative and it doesn't bore you. As a first-year medical college student, it is really helpful to visualize the epigenetic differentiation. Examples she gives are hilarious.
God does not make junk. Scientists don't know it's purpose so it is automatically relegated to the junk heap.
The 8 proteins are histones and form a protein complex known as a histone octamer, which is spool shaped (marshmallows were used in the demonstration). The 8 proteins in the histone octamer are actually 2 copies of 4 proteins, H2A, H2B, H3 and H4. DNA wraps around the histone octamer known as a nucleosome and they form chains like beads on a string making up chromatin. A nucleosome can be defined as a small length of DNA wrapped around eight histone proteins. The key difference between chromatin and nucleosome is that chromatin is a whole structure of complex DNA and proteins while nucleosome is a basic unit of chromatin. The beads on a string make up something called euchromatin or open chromatin that is enriched in genes and active under transcription (transfer of genetic instructions) which is why it is so important in epigenetics and changes in the phenotype (physical traits- e.g. appearance).
Thanks professor 😂
This was the the biggest eye opener for me in the past years. This knowledge opens so many doors.
Reading her book now after watching this a few months ago! Brilliant and exciting literature! Epigenetics is such a fascinating field! This is telling us how we can affect our future progeny!
Name of the book?
The Epigenetic Revolution by Nessa Carey@@Anonymous-zy3lh
fantastic delivery of a fantastically fascinating subject -- thoroughly enjoyable, especially being a twin myself.
We really need epigenetics to advance as a civilization, some might even say it's... nessacarey
Yes - but we need the right stimulus; and that can come only from the WORD of GOD, found in the Bible. We could easily deteriorate into barbarism, especially if we start copying animals, instead of reminding ourselves that we are made in the image of GOD.
Eyes Open!
Caleb Smit I see what you did there 😂😂😂👍
Amazing
Well done
I scored rotten childhood, alcoholism, diabetes, 40yrs depression. My parents died 2012. I went outside and stood in the sun. Instant relief then happiness. Counselling and diagnosed as having aspergers (3yrs old emotionally top 2% computational brain). I took up Zentangling Art and I am still changing & growing. It took 20 yrs after MtDna test for me to find a living relative and I discovered that 5 gens back my ancestor came from Sweden who was a Sami. I then discovered I had inherited characteristics from that cultures but not in the same configuration. I bought a good copy of the I Ching and asked HOW I could bring information from the MtDna into my conciousness. The answer was hexagram 19. It told me not to think about it or ask another question and when I asked another question I was told to not do that again. This is simplified. The overall answer was that the answer was approaching. Sooooo... I bought a book on epigenetics, wrote to a scientist and I find your teaching style that puts the text books I am reading into context. I am 72 and am like a teenager. THANK you so much.
Thank you for sharing your story, this is so valuable. Kind regards and best wishes to you
How fortunate that I in india can access this extraordinary lecture delivered so well and generously sprinkled with humor. Great contribution to science education. Have her books which are so precious for me
Dude, she is a fun and exciting person to give lectures! I can listen to her talk about science all day!!!
You make it so easy to absorb! You're an amazing professor! Thank you!
Superb presentation skills! Just the right amount of humor, story telling and information transfer to resonate with almost everyone.
Wow😂
Wonderful talk! I can't get enough of these Royal Institution lectures.
Her book, The Epigenetics Revolution, is fantastic by the way.
She destroys it. Good talk. Her book gets a bit complicated at times but this is spot on.
Absolutely brilliant presentation. I just wanted to learn a little for my pathophysiology class and left amazed!
What an incredible communicator. Science needs many more with her skill.
This is absolutely incredible! I'm completely floored.
SO intriguing! How the things, habits, nutrients we do now can genetically modify our future progeny!
Its all actually very simple to understand when you grasp what is actually occurring in terms of epigentics and how we are products of evolution - genetics and events - what we do and what is done to us
I would very much like to hear professor Carey's view on the mRNA vaccines and their potential influence on the human epigenetics!
How does mitochondrial DNA affect heredity, and how can you tell?
Finally! we have an exciting, summation of information about this field! Thank you for posting. Best explanations, clear analogies and diagrams I've ever found .I've been interested in this field for many years, though no longer a formal student. This great video brings me up to date.
One of the best speakers I've seen on this channel. We need more sweets-based analogies in scientific discourse.
Andri Eiríksson something with chocolate in it would be nice.
She is long-winded and boring.
Crocodiles and Dinosaurs share a common ancestor, crocs are not descended directly from dinosaurs.
Brilliant talk, especially your dna analogies
Showed this video to a friend. She responded, "it's true with exception to Mary, the mother of Jesus".
Nice. But molecular genetics was already about gene expression regulation, in bacteria, at the start. Sex is a molecular dialog and it has probably many and variate levels of (self) interpretation. I have discovered computer science in the working of the DNA of Escherichia Coli, a long time ago (Jacob & Monod mainly).
So much to love about this. Even all these years later rewatching it still give me all those uh-huh feelings.
What a BRILLIANT educated and informative video, love it!
Outstanding presentation
Fascinating, fascinating, fascinating. Absolutely fascinating.
🪄✨ Made with SummarizeYT
0:49 - The human genome sequence was first released in 2001, causing a huge hoopla.
2:03 - Epigenetic phenomena have been known for a long time but were not given much attention.
3:00 - Laboratory mice with the same genetic background can have different weights due to epigenetic factors.
5:01 - Gender in crocodiles is determined by the temperature at which the eggs develop, not genetics.
6:01 - Different cell types in our body have the same DNA code but exhibit different characteristics.
8:08 - Epigenetics plays a crucial role in gene expression and can be influenced by external factors.
12:00 - Epigenetic modifications can switch genes on and off, leading to different gene expressions.
14:00 - Epigenetic modifications can be compared to different flavors of jelly tots, introducing flexibility in gene expression.
16:15 - Epigenetic modifications can also compact DNA, permanently switching off gene expression.
17:27 - Epigenetic modifications can go wrong and contribute to diseases like cancer and diabetes.
19:01 - Children who have experienced abuse or trauma in their childhood are more likely to develop chronic diseases later in life.
20:07 - Epigenetics can influence what happens in organisms without altering the DNA sequence.
20:42 - Baby rats that are loved and cared for by their mothers have low levels of stress hormones.
22:03 - Epigenetic modifications in rats can be passed down from generation to generation.
24:01 - Epigenetic information is necessary for mammalian reproduction.
26:41 - Epigenetic changes can result in significant differences in physical characteristics, as seen in agouti mice.
30:03 - Mice can learn to associate a smell with something negative, and this fear response can be passed on to their offspring.
31:43 - Lamarck's theory of acquired characteristics is not entirely accurate, but epigenetic changes can be influenced by the environment.
34:01 - Trauma experienced by male mice can be passed on to their offspring.
35:05 - Epigenetic changes can affect the offspring's physical characteristics, as seen in the experiment with female mice.
36:03 - Identical twins can have different outcomes due to epigenetic changes.
First time i am watching her. Today I purchased her book " The Epigenetics Revolution. Not my subject. But i have interest.
Happy to watch. Thank you Madam. Regards
Extraordinary lecture, thank you. blessings, Kimmy
Excellent if you do it everyday in your practice with quantum
Interesting topic, delightful presentation.
A great way to transmit knowledge
If for whatever reason molecular biology doesn't work out for Nessa Carey, she can surely do well as a stand-up comedian! Very entertaining and enlightening talk!
Extremely clarifying presentation, her book is also a gem of science communication...
What a wonderful (and delicious!) lecture! I am enraptured by her humour and her passion. What a shame I am watching this 9 years after the release of the original video.
Great video! Increasingly our behavior determines our longevity. Just as weight scales provide transparency and motivate dieting, epigenetic tests now make biological age (as distinct from chronological age) more transparent and motivate us to adopt right behaviors to help us live longer.
An awesome presentation.
Her explanation about stress and childhood experiences is interesting. I was very fortunate because I had a pretty stable, happy childhood with a protective father who thought I was a piece of gold and a loving mother who was a great nurturer. Even though I was overweight and constantly bullied, I retained my happiness and confidence that has allowed me to be successful in my career and personal life. I am married to a great person, but have noticed that he is usually depressed and insecure. His sister has finally admitted that out of 6 siblings, he was given the least amount of attention and praise and was often criticized. This was needed information for me as his spouse because I can now understand why he rather that I remain overweight. When I lost most of my weight, my husband would exhibit jealousy and insecurity. He would retreat into his den, and not talk to me. Now that I have lost my mobility, my husband seems happy which I find hurtful, but with theory, I have learned that he feels empowered because he feels no one will find me attractive and he can now be the only person I can depend
Emotional abuse and neglect to keep you overweight to maintain his own well-being. Understanding his behaviour should not excuse it.
So well done. Answered questions I didn't know I had.
Great presentation. And she's just a natural. Very entertaining. 🙂
Outstanding presentation. Very clear. Congratulations!!!!
Fascinating subject, i'd never heard of this subject before. Props to the lecturer for giving such an entertaining lecture on a complicated subject! I hope you have her back again.
The DNA code starts from the same then the coding changes but the DNA coding is all the same in the start of the code. Example is like computer coding.
Code DNAMOMDAD then add on EYESLASHES or DNADADMOM Liver etc etc. It's so damn AMAZING
Thanks for making it easy to understand
I wonder how many people who watched this wished their jobs required them to play with candy in order to do it effectively? I think a lot of companies wouldn't be so stuffy if they allowed their workers to play with candy sometimes...
thank you so very much. This is wonderful. I am glad to say I was wrong.
Well worth the listen! Thank you mame
Would a babies/child’s dna receptors be affected/changed by a traumatic birth experience?
Ie would a more ‘relaxed’, non stressfull/traumatic birth experience have a better outcome for a child later in
Life?
so the dna is still the same, just the little "jelly" dots that attach to the dna that a person might develop while interacting with his environment? But what's the mechanism behind the epigenetic changes (my guess it's still the DNA that gives instructions to the protein to make the epigenetic changes)...I mean could epigenetic changes lead to the eventual creation of a new species? Thinking more ahead, how much can we augment our body through tweaking the expression of various genes, like would we be able to grow a new arm through epigenetics, or is that sort of mutation still dependent on the manipulation of DNA? You say that the little "jelly" dots, sorry I forget the exact term you used for those molecules, attach to the genes and affect their individual expression, but how many genes do we have, what are each gene's functionalities, how does each gene interact with each other, and what explains the difference between us and a chimp or a bird or something? God damn it get more research done lady!
My back is hurting from watching all these Royal Institute videos laying on my bed at 1AM in California, and I also don't have a car to go to work tomorrow morning, and I think it'd be really nice if DNA technology can allow me to grow a pair of wings! (though the image might be a bit grotesque) so I can fly around to work and buy groceries or something...
Such an amazing talk ma'am..really really loved it to the core...
All I want to do right now is eat strawberry laces and jelly tots.....on a serious note, this lecture was FASCINATING - thank you Nessa for your fabulous energy teaching this
Oh no! Your exposure to the video (environmental factor) has changed your mental content, which could change your behaviour which could change your epigenetics, which could change the future of your offspring?
Good grief this rabbit hole goes deep...
Amazing teaching learning knowledge about the modification and genetic codes sequence of genome 🙏🙏👏👏❤️❤️💐💐
Mary Poppins is awesome at science!!
Thank you for the very fascinating and lively lecture! I love it!
There's one thing I am confused about. So if the histones are wrapped around our genes, and say you become a smoker (but no one in your family tree extending hundreds of years smoked) and the chemical tag is added to the histones to make that gene become 'expressed', does that mean that the 'smoker gene' is predetermined? In other words, will I have a 'smoking gene' by default that is turned off, but will only be turned on if I smoke?
In all biology textbooks, Galapagos finches are mentioned as a prime example of evolution. However, a relatively recent study conducted by Peter and Rose-Marie Grant documents that the changes in beak size and shape of these birds that Darwin observed do not take millions of years, but change continuously at a rapid rate of as little as two years and that the changes are reversible. It is very likely that it is epigenetic adaptation, not evolution in the Darwinian sense. This certainly also applies in many other cases where adaptation is interpreted as macroevolution today. The theory of evolution must and will be rewritten.
What a great presentation. Loved it!
Great presentation 👏
I'd love her as a professor for all my bio classes
First-rate presentation on this topic. Thanks very much.
so this evident against genetic and materialistic determinism, true?
Unfortunately she was not able to explain how homeostasis knows which genes to turn on and off. Or how a certain chemical affects certain genes and not others. Are certain aspects of evolution Lemarkian? Evolution takes place because of needs and choices? Do epigenetic changes eventually lead to sequence changes?
Fascinating.
Interesting material and very well done presentation.
I would love to know the other side of the experiment, where mice with caring mothers were put with not so caring mothers and then had a traumatized life. What happens when a mice with a not so caring mother is put with a caring mother? They get better? They get "normal"? They don't get better?
I don't know where to ask this question :( If someone could give me a clue, i would be very grateful.
1:16 for a believer crediting or thanking God doesn't mean discrediting or not thanking scientists.
It would be interesting to know what foods could turn on or turn off gene expression in humans and the outcome of the change.
Thank Nessa, it is my pleasure to attend your tutorial today at MCRS
To those enthusiasts who have this presentation: please go and read the two books. But you have to read both.
How would you explain a Monarch Butterfly’s migration from central Mexico to Canada and back to the same tree? There are four generations in a year. The migration is a year long. The returning butterfly is the great grandchild of the one that left the overwintering tree. How is the information passed on through the generations?
Alex Chen Birds rub themselves against certain trees to leave a trace, so that might be it.
Butterflies experience reincarnation! Duh!
I hope everyone enjoyed this.
35:00 I am not convinced , wouldn’t there be another explanation for that ?
Brilliant talk, engaging presentation..... - i feel for the mice, though.....
well done and entertaining presentation on the topic of epigenetics
I really enjoyed this talk thank you
Its really a great lecture never had idea management student can enjoy science.
all i can give to this lady is 🙇 Respect! amaizing
Fantastic, Love the energy your brought to your book The Epigenetics Revolution"
I wonder if you can see the link between Epigenetics and Buddhist Karma.
(They are both very deep matters)
Any Buddhist's out there pls read this and think....
We need more real scientist dedicated to discover and instructs and inform us broadly . Thank Madam
What a brilliant lady!
Dear Royal institution.
There are educational providers online who are of the opinion that interrupting their productions with advertisements is counterproductive.
Is the income from ads really essential?
One really has to wonder how you managed back in Faradays time.
Perhaps you could precede broadcasts with a short statement asking for support.
Tell your audience that it enables ad free content.
You might be surprised at the uptick in donations received as a result.
Just a suggestion, your content is greatly appreciated but the interruptions do spoil it.
Wow, really enjoyed this lecture. Any sociological/psychological applications or assumptions linked to these findings? ie, poverty, oppression, consistent trauma etc...
excellent video to describe epigentics, its a subject i wanted to write on next for my blog.
Nithya
Intellectual, Kindle the mind to know more about epigenetics Thanks
I have a question about epigenetic modification that is...Are these modifications trans generational in mammals? Or are they inter generational?
Really good - packed with interesting insights and good for the RI to tackle what is admittedly a controversial topic.
How do you determine if a characteristic is truly determined epigenetically or if there is some other factor, like the chemicals given off by gut bacteria, or some changes triggered by viruses, or some other mechanism I can't think of just now?
Great video! I can imagine that practical living advice can come from epigenetics, like how i can change my own in a positive way. Any chance to get that?
Hmm, for example if you don't smoke, your epigenetics for requesting more nicotin don't get switched on and your kids probably won't smoke either. Does this answer your question?
Are the 8 proteins in the nucleus of the same composition in everyone, or are they widely differing?
I never understood this: If you block a gene from being expressed, what gene is expressed in it's place? Wouldn't it be a wrong one, for example heart cell instead of skin cell? Is there an alternative healthier gene? It can't be nothing. If i have, let's say, a mutated finger and i block that gene off, what would be in it's place? I think is absurd that there would be no finger.