Bone tissue engineering | Bone healing

After bone cell communication, in this video, we will talk about two different mechanisms of bone healing (Endochondral ossification and Intramembranous ossification). After this video, I think we can talk more about biomaterials and the recent research on bone tissue engineering.
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References:
1. Zhu, Guanyin, et al. "Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds." Bioactive materials 6.11 (2021): 4110-4140.
2. Schipani, Ernestina, et al. "Regulation of osteogenesis‐angiogenesis coupling by HIFs and VEGF." Journal of bone and mineral research 24.8 (2009): 1347-1353.
3. Bahney, Chelsea S., et al. "Cellular biology of fracture healing." Journal of Orthopaedic Research® 37.1 (2019): 35-50.
4. Hu, Kai, and Bjorn R. Olsen. "Vascular endothelial growth factor control mechanisms in skeletal growth and repair." Developmental Dynamics 246.4 (2017): 227-234.
Attributions:
1. www.freepik.com/
2. pixabay.com/
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The music tracks in this video is composed by:
1. Expand by @HazyHazyHazy
2. Timeless by @HazyHazyHazy
Download: hazymusic.bandcamp.com/
SoundCloud; / hazy_music
/ @hazyhazyhazy
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Timestamps:
00:00 Bone repairs details
01:34 Two Different ossifications (making bone tissue)
02:01 Intramembranous ossification
02:57 Endochondral ossification
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#bone #stemcells #regenerativemedicine

[@upgrade_it]

So our vascular system is dynamic and constantly changing its network to better support areas with low oxygen? Never thought about it in this way.