Stem cells understand geometry. How?

One of the recent hot topics in tissue engineering is utilizing the topographical features of biomaterials for controlling stem cell behaviors. The cell understands the geometry of the surface they attached to, and based on that, they change their fate and behavior. We still don't know the exact mechanisms which make this field interesting. This is one of the topics that I wanted to talk about for a long time. I hope you enjoy it.
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References:
1. www.nature.com/articles/srep0...
2. pubs.rsc.org/en/content/artic...
3. onlinelibrary.wiley.com/doi/a...
4. onlinelibrary.wiley.com/doi/a...
5. onlinelibrary.wiley.com/doi/f...
6. www.sciencedirect.com/science...
7. www.sciencedirect.com/science...
8. www.nature.com/articles/s4159...
9. pubs.rsc.org/en/content/artic...
10. onlinelibrary.wiley.com/doi/a...
11.growthcones.neuroscience.umn.e...
12. pubs.acs.org/doi/abs/10.1021/...
13. www.frontiersin.org/articles/...
14. www.sciencedirect.com/science...
15. www.nature.com/articles/s4146...
Attributions:
1. www.freepik.com/
2. pixabay.com/
3. drive.google.com/file/d/1cYkj...
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The music tracks in this video is composed by:
1. This Too Shall Pass by @ScottBuckley
• 'This Too Shall Pass' ...
/ @scottbuckley
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Timestamps:
00:00 Stem Cells understand the topology
01:33 What is surface roughness?
02:12 How we can use surface roughness?
02:47 Stem cells understand surface patterns
03:46 How cells understand geometry?
05:34 Stem cells understand the curvature geometry
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#biomaterials #Stem_cell #scaffold

[@WrylyRiley]

Amazing video, well done!

[@Find-the-Devil]

Glad you enjoyed it

[@haroldhon5094]

I love the style of your videos, and that clip at the end was amazing!

[@Find-the-Devil]

Thank you for your encouraging comments.

[@leechleyf1197]

Yo, I found your comment in on of sciencerly's video and decided to check your channel. Loved your videos and keep up the content!

[@Find-the-Devil]

Hey there. Thank you for this amazing comment. Hope you enjoy future contents as well.

[@ocno]

I love the pace of your videos, you manage to move forward quickly while always keeping new information and necessary context digestible. And a great choice of topic as usual, cell differentiation is so amazing.

[@Find-the-Devil]

Thank you Florian. Appreciate it a lot. Nice to see your great and encouraging comment.