Bone remodeling and repair
ฝัง
- เผยแพร่เมื่อ 13 ต.ค. 2020
- What is bone remodeling and repair? Bone remodeling is when old, brittle bone tissue is removed or resorbed and gets replaced by new bone tissue. Remodeling also occurs when reshaping your bones after a fracture or when repairing micro-cracks which form during ordinary activities, especially when your bones are under stress, like after lifting heavy weights. Find our full video library only on Osmosis: osms.it/more.
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why this gave me more understanding than my college..i love it
Focused on lecture rather than Girls 😂😂😁
Willl my bone density will grow after quitting drugs? I am 23+.
Because you are fool 🤣
Great video. ties everything together nicely. Decided to review bony remodelling today and fascinating what you can pick up again on revision. Initially when learning about bony remodelling I never really thought about the significance of RANKL , but with drugs such as Prolia , a RANKL inhibitor , it becomes obvious as to why the fundamental understanding of the physiological processes is vital to clinical practice with associated pathological states such as Medication related oseteonecrosis of the jaws. Many thanks.
Bone remodeling in short:
-Osteoblast release M-CSF & RANKL → Convert monocytes into osteoclasts → ↓ Bone mass
-Osteoblast also release Osteoprotegerin (OPG) → OPG will inhibit RANKL → ↑ Bone mass
This was really helpful plus the illustrations are adorable!! Thank you so much.
Finally understood the mechanism after 5 retake. love this type of resource, really insightful and articulate.
We're glad it helped, Dhruv! 🙏🏼
The illustrations are fabulous
I've searched more than 1 hour for a video like this, thank you so much 😍 this sums up everything i want about bone tissue 👏
Hi Eva, Glad it was helpful!
Read your bible! (KJV, preferably) ♥
Simple yet deep and well explained. Thanks a lot. Please make more animationlike this. I really appreciate it. Gbu all team!
Thank you Mikhail for that wonderful feedback!
Pretty helpful! Thanks!
What a vivid way to present such hard topic. Thanks a lot !
Thanks for your wonderful comment! 🥰
Great video! Helped me a lot!
That was exactly what was needed
I would have loved to see more infromation about hormones and their influence on bone remodelling, such as the osteolytic effect of cortisol and such. An all-in-one video of what hormones affect bone remodelling.
Great visuals and wonderfully concise and explanatory! Thanks so much!
You're very welcome! Thanks for letting us know!
Another great video by the Osmosis Team! Thank you!
Thank you too! 🙏🏼
Thanks Bro! this really helped me.
Thank you for sharing. Please we would love to see more videos like this
This is the perfect video for this subject. Thank you so much!
Glad you think so!
Osmosis makes med school easy♥️love this channel. So accessible
Yey! We're glad to be of help to your medical journey! If have time, feel free to sign up for a free trial at osmosis.org so you can access more of our video library and other study features. 😊
Dear Osmosa,,, please make a video about closed fracture.. thanks a lot.
Amazing. Now i remmeber the core of a complicated process in our body. TKs a lot
Glad to hear that, Minh! ❤️
thx! it help me a lot
That's wonderfully explained..Made understanding very clear just in 5 min..
Thank you so much
Glad it was helpful, Foram! ❤️
Thank u! ♡
Thank you!
Great, thank you.
Great explanation ma sha Allah!
Wow, this is really informative. Thank you! I lost 2 Parathyroids after a messed-up operation. Still don`t know how to deal with this, but trying and learning. 😰
Sorry to hear that. Katharina. We hope you're doing better now. 🙏🏼
nicely explained :)
Thank you very much
One of the best video on bone remodeling
Wow, thanks for that feedback!
Amazing ♥️♥️♥️♥️ thank you very much
❤️❤️.. plz make a video on osteoporosis
Very brief vidio......Thanks alot
Very clear and straight forward
Thanks, Mary! 👍🏼
This is amazing
Thank you!!! It makes so much sense now!
Glad to help! 😊
Well explained 👏👏👏, thank you so much 🙏
Glad you think so, Ramokunupi! 🥰❤️🙏🏼
Awesome explanation. Loved it.
Thanks, Chris! 😊
How about left humerus? How many months it takes before healing?
U ppl.arw.doing such a great teaching
..thanks a lottt
Hi Navyashree, thank you, we're glad you find our videos useful! :)
Wow thats so helpful...Thanks alot. In the midst of confusion and infodemic, its like a hopeful rays.
Glad it was helpful! 💫 🥰 💖
excuse me but do you have a video explaining mechanism of healing of bone's fracture?
Amazing content and animation! Thank you!
Most welcome, Melina! 😊
God bless you people
Watching this on my way to my test. Thank you
We hope it went well! 🙏🏼
I have a question please regarding Wolff's Law: if we say that
Applied pressure results in bone resorption, while applied tension results in bone formation.
is that correct or not?
Are these cytokines that these cells use to signl or use as a communication to start og stop a process?
excellent job
Many thanks! ❤️
Really hepful thank you so much 💜
Our pleasure! 😊
You are a life saver ❤️
Always glad to help, Muhammad! 🥰
Perfect👌Tnks✨🌸
Awesome
Excellent ... well done ...
Thank you, Mahu! 🙏🏼
Thank you. ❤
You're welcome 😊
Thank you so much this is amazing
You're so welcome! 💖
Understand thanks. A lot
Happy to help 🙏🏼
I had 12 years ago a femure fracture very ugly caused by a tumore. I had surgery ofcourse the doctor said he clean everything there very good and he put me a metal plate wich I still have now and than I had the chimioterapy treatment. After 3 years I started to go slowly to gym and workout slowly but still even now after years I still cannot do the exercises for legs I did before the fracture because some pain during workout. You think the femur after this damage has healed properly? I will like your opinion also. Thank you
Thanks a lot !!!
We hope our video helped! 🥰
Great video, thank you
You're welcome, Euge! 🥰
great vid
Thanks, Hanan! 😊
very appreciable
Thanks!
why there is resorption in one side and the deposition in the other side not in the same side ?
hi, could you add the bibliography used to make this video? it was so useful to me and i'd like to read sources too
Hi Francesca! You may access this information when you hop on osmosis.org! Please feel free to sign up for the 7-day free trial (no card needed) anytime 😊
Great
What is the duration of this process
woow I love this one, thank for amazing video :)))
Glad you like it, Siti! 🙌🏼
This is nice
amazing❤❤❤❤❤❤❤❤❤
I'm gonna send this video to my professor 💀✌️
the best explanation 😍
Thanks, Dunya! 💕
Really nice
Thank you! 🥰❤️🙏🏼
Parathyroid gland stimulates osteoclasts (not osteoblasts) for bone resorption to occur. Small mistake at 5:05.
how long is it ? how long the process go ?
You are the best ❤️
Aww.. thank you Kiaan! ❤️
holy shit that's so good
Amaaaaazing !!!!
🙌🏼 💕 ✨
Tq
Hello Sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off fractured line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....
Great ❤❤❤❤❤🥳🥳
This is so good but i dont know english well so it was hard to understand😭😭 but tysm anyways that helped a lot🥹🫶
Medical college life is easier with osmosis! 💗💗
Glad to be of help! 😊
My daughter had PAO surgery. The coverage is good no doubt. She still has pain and is very thin, could bone remodeling be an issue?
Excellent presentation , but as far as I know osteoclasts doesn't produce COLLAGENASE , it is produced by osteoblasts actually , bone resorption by osteoclasts at it's clear zone (at ruffled borders) mediated by carbonic anhydrase , secondly it pump out hydrogen ions( after CO2 hydartion - H2CO3 formation - breakdown into Hydrogen and carbonate ions -then pump out hydrogen ions) which lowers pH , lysis of collagen in acidic media , which leads to bone resorption , Plz tell me if I m wrong
Does this process take place in the skull bones like the jaw or cheekbones?
Good question
When the bone is getting remodeled due to stress fracture , does it add 2-3 inches in height growth . When fully recovered
what if person diabetic? how will heal
What do you think about bonesmashing?
Monocytes looks like a friendly thing 😊
Monocytes are the most badass myeloid cells
Where's repair???
I wish my actual lecture was that easy with less deatails :(
Nice
Thanks! 😊
@5:03 I think you’re mistaken. Shouldn’t the osteoclast be reabsorbing bone to release calcium in the bone?
Hi Kevin! Thanks for pointing this out. We've notified our team about this so they can have the information reviewed. 😊
wow
This didn't really explain how the bones know what shape they're supposed to be. I am particularly interested to know why spinal stenosis doesn't reverse itself relieving pressure on the spinal cord.
I think there is a mistake at 2:41. Myeloid progenitor cells come from hematopoietic stem cells, not lymphoid stem cells.
Thanks for pointing this out! Our team will be reviewing this information and update the video as needed. 🙏🏻
I think there is a small mistake, yellow bone marrow does not produce blood cells as was indicated in the video. That is actually red bone marrow typically found in the epiphysis
Thank you so much for bringing this to our attention, Grant! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊
So...is bone death reversible?
I just failed my exam because i never prepare for ortho sub the intro was so boring in my university lecture i need to start with this ✊🏻🤞🏻 wish me luck everyone i m gonna start studying this video give me so much hope i find it it very interesting and its very easy to understand this😁
Hi Pitchet! You can rock this exam! If you can, you may sign up for a free trial at osmosis.org so you can access our entire video library and study resources to help you ace your exam. This might help! We won't be asking for your bank details or anything, so no worries. 😊
Ily