No one affected my life as much as Zach He has increased my productivity so much I’m so used to his explanation technique that today when my professor was explaining this subject he wasn’t explaining bad but I knew what I was missing which is an explanation which is not only reading slides and showing pictures but it’s drawing and explaining the drawing step by step then show me the whole picture that ease the remembering of what he has been explaining for me since the first minute unlike the slides which when the professor was explaining the third slide I had already forgotten what was explained in the first slide. Thank you thank you thank you zach❤
What the actual F? I am very smart. So are my professors. This guy does laps around us all. He is a national treasure. No doubt, the best instructor I’ve ever had. Billion dollar Treasure this man right here.
Now that I have seen a couple of your videos, I can assert that you maintain a fantastic quality of information and teaching style in your lectures!!! Immensely helpful to everyone interested in human hormonal mechanisms. Thanks a lot for your efforts and sharing this video!
Got a test today and have been listening to these videos and it helps everything in between. My professor is super smart but you’re super smart and make it easier to understand. Great explanations and communication.
No body can explain anatomy and physiology as much as you did zach thanks a lots for everything 🙏 I am going to tell every medical or even dental student I meet on your channel Ninja nerd God bless you 👍
I love your amazing videos. My diploma should say graduated from Ninja Nerd University! A small suggestion that would make this perfect is adding captions. I and most my friends like to listen to your videos at 1.5x or 2x speed and it's great but some of the names become difficult to make out. Another reason is me having a photographic memory so seeing the word in captions makes it stick. Keep up the good work! You're helping countless students not die of stress!
During breast feeding, prolactin secretion is increased......so breast feeding and estrogen should inhibit the release of PIH...right?? Then the sign must be negative By the way.....great explanation sir...lots of love and respect from India
I think he meant that breastfeeding, estrogen leveles, birth controls leveles are stimulating the production of prolactin.You are right, there should be a negative sign on the effect of dopamine secretion
The part that you muted the original sound and put your voice again on video was kinda interesting. Thank you for your videos. You make this world a bit better. :)
I wanna be say thankss a lot to you. I am a vet student so ı have limited sources and my profs cannot tell the lecture cleary . Their slides is so confucing source so because of this that uni life is like a hell to me before ı met your chanel . Thanks a lottt ❤ videos are about more human medicine but some basics is same . That part is enough to me for a beginner or maybe intermadiate level to this major.
@@t4_2g Estrogen will stimulate the Anterior Pituitary to release prolactin for breastfeeding. However, once it reaches so high, the prolactin will actually inhibit GNRH from releasing FSH and LH, essentially negative feedback. This explains why it's harder (but not impossible!) to become pregnant again while breastfeeding d/t anovulation. As for OCPs, it depends on the type and concentration of estrogen/progesterone/progestin.
If PIH is inhibited prolactin is produced w/c is necessary for milk production. Therefore, breastfeeding can inhibit PIH because breastfeeding promotes prolactin release. Estrogen & Combined Birth Control Pills can inhibit milk production. Which means they can trigger PIH.
GnRH IS Released by preoptic nucleus or arcuate nucleus.. i found on one book that it is released by arcuate nucleus.. i get confused please clarify me sir?
Dude when Zach starts talking about the inhibiting versions of hypothalamic hormones, the sound of the video doesn't match the visual. But a couple of seconds later it's fixed.
So, take my words with a grain of salt, but I believe what he was saying is that normal levels of Dopamine inhibit the lactotropes. So normally, there is a low level of prolactin in the body. BUT, when there is a low level of dopamine, the lacotropes are no longer being inhibited, and so they produce higher levels of prolactin. Which I believe is why women commonly experience the "baby blues" at around day 4 or 5 of thier baby's life, because this is when the thick, fatty, colostrum transitions into white breastmilk. Breastfeeding and nipple stimulation also increases the production of Oxytocin, the "cuddle hormone" or bonding hormone.
Really the incredible videos this are... Thnk u so much for teaching in such a wonderful manner... This really makes all the concepts crystal clear.. Thnk u really a lot. .
Thanks sir ,buy i have question,, I'm confused, anterior pituitary gland have different types of cells? because you(sir) say this specific signal which come from hypothalamus to stimulate that specific type of cell ,to secret that specific Harmon
Yes, in the anterior pituitary, there are different cell types that produce the respective hormones and also have receptors to respond to corresponding releasing and inhibiting hormones: - Somatotrophs produce and secrete growth hormone (GH). - Lactotrophs produce and secrete prolactin (PRL). - Thyrotrophs produce and secrete thyroid-stimulating hormone (TSH). - Corticotrophs produce and secrete adrenocorticotropic hormone (ACTH).
I’m a little confused, this video is second in the playlist series.... but It seems like you’re continuing off from another video. So this can’t be the second video in your endocrinology playlist series. Can you link me the previous video of where you seem to be continuing off from?
Thought the control is only by negative feedback for most of the hormones and not necessarily each to have its own inhibiting hormone. This has confused me alot
No one affected my life as much as Zach
He has increased my productivity so much
I’m so used to his explanation technique that today when my professor was explaining this subject he wasn’t explaining bad but I knew what I was missing which is an explanation which is not only reading slides and showing pictures but it’s drawing and explaining the drawing step by step then show me the whole picture that ease the remembering of what he has been explaining for me since the first minute unlike the slides which when the professor was explaining the third slide I had already forgotten what was explained in the first slide.
Thank you thank you thank you zach❤
hope he can correct your sense of direction, Zoro....
What the actual F? I am very smart. So are my professors. This guy does laps around us all. He is a national treasure. No doubt, the best instructor I’ve ever had. Billion dollar Treasure this man right here.
🤝International treasure
not just national but an international treasure...we love you and thanks alot
@@owoeyepaul8995 qqqq
Please, don’t stop making these videos!!! You are king of teaching
Now that I have seen a couple of your videos, I can assert that you maintain a fantastic quality of information and teaching style in your lectures!!! Immensely helpful to everyone interested in human hormonal mechanisms.
Thanks a lot for your efforts and sharing this video!
Got a test today and have been listening to these videos and it helps everything in between. My professor is super smart but you’re super smart and make it easier to understand. Great explanations and communication.
No body can explain anatomy and physiology as much as you did zach thanks a lots for everything 🙏
I am going to tell every medical or even dental student I meet on your channel Ninja nerd
God bless you 👍
I love your amazing videos. My diploma should say graduated from Ninja Nerd University!
A small suggestion that would make this perfect is adding captions. I and most my friends like to listen to your videos at 1.5x or 2x speed and it's great but some of the names become difficult to make out. Another reason is me having a photographic memory so seeing the word in captions makes it stick.
Keep up the good work! You're helping countless students not die of stress!
Looking forward to NINJA NERD UNIVERSITY
That's correct. Ninja Nerd University >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> med schools out there. lol
I too am a medical student. Your videos single handedly got me an A on one of my tests
Amazing explanations... We are lucky to have these lectures on medical topics from an expert teacher like you..
U have stimulated my whole endocrine system with ur lectures
U r amazing
Myself an anesthesiologist..
R u a doctor???
Me student of anesthesia
what do you do? these videos are incredible!!! holding my hand through school!
+Sarah H. We are so happy to hear that Sarah! Keep on studying and tell your class mates!
You are a hero! The best teacher I have ever had (I am into my second master's degree in Nursing) and you are the best there is! THANK YOU!
you are a genius; Everything is so much clearer with you ! Please Never stop, you are the best med university 🤩
thank you for sticking through the whole process of making this video
Amazing you are really a thing ... thank u so much 🌸
I’m a medical student and ur videos always save me before exams
Woow ,after a long time of hustling to understand hypothalamus,guy broke it down in just an hour.i appreciate @ ninja nerds great work really🎉🎉🎉🎉🎉🎉
I can't compare you with my lecturers,you are a Ninja Nerd indeed,thanks alot.
I am proud of your hard effort for student.Amazing lectures Sir.
Your videos help me so much studying physiology ! I got 8.9/10 at my first partial, hoping to do as good or better for the second one !
During breast feeding, prolactin secretion is increased......so breast feeding and estrogen should inhibit the release of PIH...right?? Then the sign must be negative
By the way.....great explanation sir...lots of love and respect from India
Thats what I thought too
I think he meant that breastfeeding, estrogen leveles, birth controls leveles are stimulating the production of prolactin.You are right, there should be a negative sign on the effect of dopamine secretion
yeah zach was talking about prolactin so yeah the sign should be negative
Beautifully presented - clear - interesting- MEMORABLE 🥇✅ Thank you
The part that you muted the original sound and put your voice again on video was kinda interesting. Thank you for your videos. You make this world a bit better. :)
Isa kang alamat!
Love from Philippines ❤
I think the analysis at the end may be misleading at 15:05 , you said breastfeeding increases PIH which isn’t a secondary stimulus
i was thinking the same thing, thank you for pointing that out!
I'm so glad I found this video. Really helps visualize and better understand the research paper I was reading about the HPA axis
I wanna be say thankss a lot to you. I am a vet student so ı have limited sources and my profs cannot tell the lecture cleary . Their slides is so confucing source so because of this that uni life is like a hell to me before ı met your chanel . Thanks a lottt ❤ videos are about more human medicine but some basics is same . That part is enough to me for a beginner or maybe intermadiate level to this major.
There is a typo @14:45, breastfeeding inhibits Dopamine release because Dopamine inhibits Prolactin, otherwise great video, thanks!
What about estrogen and bc pills?
@@t4_2g Estrogen will stimulate the Anterior Pituitary to release prolactin for breastfeeding. However, once it reaches so high, the prolactin will actually inhibit GNRH from releasing FSH and LH, essentially negative feedback. This explains why it's harder (but not impossible!) to become pregnant again while breastfeeding d/t anovulation. As for OCPs, it depends on the type and concentration of estrogen/progesterone/progestin.
I was thinking the same, thank you!
@@honeybellebuzlucay5867 no problem! 🙂
فدوة لربك ع هذا الشرح
You have a gift. Thank you for this sir🙏🏽
Amazing way of explanation...love from India🇮🇳
Which college??
11:20 "Thought we wouldn't notice. But we did." - Tony Stark
Great video! You're helping me ace my A&P classes, sir.
I thought that something was wrong with my laptop lol
Subhan Allah ❤️🥰
So beautiful 💚💚😇
Thank You Zach! Thank You Rob and Kristen!
Zach should be put in a museum
Thank you🤗 very nice lecture you cleared my concept on NPO
Only suggestion plz give us time to take screenshot at the end
this is my favorite youtube channel ❤ ❤
What's really crazy is 500'000 people watching this to save their grades and only over 8'000 having the gratitude to like.
Wouldn't breastfeeding, high estrogen levels, and birth control pills, all inhibit PIH release?
Dave Buikema right ?!?! I checked that 1000 times 😓😓😓
right?
If PIH is inhibited prolactin is produced w/c is necessary for milk production. Therefore, breastfeeding can inhibit PIH because breastfeeding promotes prolactin release.
Estrogen & Combined Birth Control Pills can inhibit milk production. Which means they can trigger PIH.
@@edilbertoramos3045 Estrogen inhibits milk production? Also if their breastfeeding, wouldn't they need more milk (not less)?
He said they can influence PIH. That means either inhibit or stimulate.
This is really good! I have just seen this today and I'm impressed.💯
GnRH IS Released by preoptic nucleus or arcuate nucleus.. i found on one book that it is released by arcuate nucleus.. i get confused please clarify me sir?
Very effective lecture.....love from Nepal,🇳🇵🇳🇵🇳🇵🇳🇵
Love from Pakistan
Dude when Zach starts talking about the inhibiting versions of hypothalamic hormones, the sound of the video doesn't match the visual. But a couple of seconds later it's fixed.
lol thanks for this comment,i thought im having some kind of visual error! XD
Thanks for the video, but you didn´t mention what stimulates the GnRH
Cheers
Can you please give us a screen of the finished white board so we can screenshot what we've learned to help us remember!!!
Hi! thank you..
how can breast feeding stimulate Dopamine which decreases milk?!
you wrote it has a + feedback on PIH (Dopamine)
So, take my words with a grain of salt, but I believe what he was saying is that normal levels of Dopamine inhibit the lactotropes. So normally, there is a low level of prolactin in the body. BUT, when there is a low level of dopamine, the lacotropes are no longer being inhibited, and so they produce higher levels of prolactin. Which I believe is why women commonly experience the "baby blues" at around day 4 or 5 of thier baby's life, because this is when the thick, fatty, colostrum transitions into white breastmilk. Breastfeeding and nipple stimulation also increases the production of Oxytocin, the "cuddle hormone" or bonding hormone.
Phenomenal lecture 👌
Boom! Another topic on finger tips.
Thank you so much! you are the best ❤ BTW those neurons are sooo funny and cute!❤
In your previous video u said its arcuate which does releasing factors and inhibitory factors and now u turn to pvn
Easy,
To the point & interesting lecture...Thanku soo much sir .. God bless u 👍
Well done 👍
Alright, we're moving 5:58 ❤❤❤
where there are inhibitory versions of each hormone, shouldn't there also be a releasing version of Prolactin inhibitory hormone(dopamine?)
U r a science wizard 🙌💕🙏💥✨👑💫 doctor
Really the incredible videos this are... Thnk u so much for teaching in such a wonderful manner... This really makes all the concepts crystal clear.. Thnk u really a lot. .
Love your lectures !! Thank you sooo much
love from sri lanka !!!!!!!!
Spectacular!
We have Jr Najeeb here 👍👍👍
Thanks sir ,buy i have question,, I'm confused, anterior pituitary gland have different types of cells? because you(sir) say this specific signal which come from hypothalamus to stimulate that specific type of cell ,to secret that specific Harmon
Yes, in the anterior pituitary, there are different cell types that produce the respective hormones and also have receptors to respond to corresponding releasing and inhibiting hormones:
- Somatotrophs produce and secrete growth hormone (GH).
- Lactotrophs produce and secrete prolactin (PRL).
- Thyrotrophs produce and secrete thyroid-stimulating hormone (TSH).
- Corticotrophs produce and secrete adrenocorticotropic hormone (ACTH).
Sir is gonadotropin releasing harmone relase from pre optic nucleus or arcuate nucleus?
Hello may i ask what references you use for your lectures?
i loveee your videos, thank you so much. I have one question, isn't somatostatin secreted in the paraventricular nucleus? 🤔
Excuse me, doesn't breastfeeding inhibit PIH?
I’m a little confused, this video is second in the playlist series.... but It seems like you’re continuing off from another video. So this can’t be the second video in your endocrinology playlist series. Can you link me the previous video of where you seem to be continuing off from?
+Yasmin Ali hypothalamus-posterior pituitary connection
th-cam.com/video/13yGwDAvbQI/w-d-xo.html
It is in the correct order now, thanks
Ninja Nerd Science thanks so much!
Yes, there's a video on posterior pituitary gland before this.
Do you have a video on positive and negative feedback?
You are amazing!!! Thank you so much; make med school so much easier🙌❤
Genesis is to music what you are to Physiology simply supreme
awesome thanks ninja nerd
Excellent video
Why does the preoptic nucleus look like Madam Hooch, the flying instructor at Hogwarts 😭
😂
😂😂😂
😂😂
Thank youu
Please can you do other physiology lectures like on GIT and brain and netvouse system please please
What is the difference between the follicle stimulating hormone and the luteinizing hormone?
+Caitlyn Nichols hello! Check out our video on the ovarian cycle in the reproductive playlist.
thank you :)
amazing sir g ur the best medical teacher and Dr we creates more subscriber for u sir
thank u sourabh
Love From INDIA
Hormone check plus male blood test results:can Graves' disease cause this ? Dhea :11.500(0.44-13.40)
Follicle stim hormone:4.17(1.50-12.40)
Luteinising hormone:3.63(1.70-8.60)
Total testosterone:17.1(7.60-31.40)
Free testosterone calculated:0.247(0.30-1.00)
SHBG :57.7(16.00-55.00)
Free androgen index:29.64(24.00-104.00)
17 beta oestradiol:76.8( 41.00-159.00) symptoms:low mood ,low libido ,anxiety...I was diagnosed Graves' disease 2008'..
0opiior8rine
YOU are best bro !!!!
Thank you sir ❤
GNRH is released from the arcuate nucleus not the pre optic
No dude it's pre-optic I just checked
Sweet Deal!
Sir you don't mention anterior nucleus in supra optic reagion.
Amazing , thank u so much boss 🌹❤️
you are really helpful, thank you !!!!!!
you are the best
great video ...
Wonderful
Is there any role of supraoptic nucleus in the stimulation of TRH
excellant!
but i have a question to ask sir what other activities do u do especially in hospital
GHRH and somatostatin is released by ventromedial nucleus no??
and Arcuate nucleus releases prolactin inhibiting factor or dopamine???
prolactin inhibiting hormone is dopamine
Can we get the notes of this topic sir…?
thanks sir
My request is after you done drawing step aside for a sec so that I can take a screenshot please and thank you
Thanks, sir
Is there a prolactin releasing hormone??!
Anterior pituitary #1
Thought the control is only by negative feedback for most of the hormones and not necessarily each to have its own inhibiting hormone. This has confused me alot
Thanx man