Hypothyroidism | Clinical Medicine

Premium Member Resources: www.ninjanerd.org/lectures/hy...
Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Hypothyroidism. We will discuss the pathophysiology, including the decreased production of thyroid hormones and its effects on the body's metabolic rate. The lecture will include a discussion on the clinical manifestations, such as fatigue, weight gain, cold intolerance, and constipation. The digital presentation will begin with the diagnostic approach, highlighting the importance of TSH and free T4 measurements. Finally, we will review management strategies for Hypothyroidism, emphasizing the use of levothyroxine to normalize thyroid hormone levels and improve symptoms. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Hypothyroidism Introduction
0:56 Primary Hypothyroidism
6:19 Autoimmune-Related Thyroid Destruction
14:39 Infectious-Related Thyroid Destruction
16:57 Iatrogenic-Related Thyroid Destruction
17:37 Wolff-Chaikoff Effect
20:18 Secondary Hypothyroidism
26:53 Classic Findings- Goiter
29:53 Classic Findings- Metabolic Dysfunction
33:34 Classic Findings- Neurological Dysfunction
35:03 Classic Findings- Cardiovascular Dysfunction
38:26 Classic Findings- Reproductive Dysfunction
40:17 Classic Findings- Gastrointestinal Dysfunction
41:31 Classic Findings- Integumentary Dysfunction
45:00 Myxedema Coma
51:33 Diagnostic Approach to Hypothyroidism
55:45 Treatment of Hypothyroidism
57:48 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Hypothyroidism | Physi...
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#ninjanerd #endocrine #hypothyroidism

[@jonosay854]

Here We Gooo
*7 minutes in and you've explained more to me than my Endocrinologist has in 18 months 🙌🏽

[@directioner8039]

What a legend. I let out a chuckle when you said "chillin bro" as you explained the clinical presentations. It is the little things that show how passionate you are about what you do

[@drmadhavmehta]

Thank you for these amazing lectures Zach! ❤️

[@ridmitharushi9585]

thank you for everything you do! you're a LEGEND!!!

[@mglapid10]

You’ve been a big help with my exams!!

[@marinatejeda1993]

Thank you for all your help!

[@medic_wind2518]

Its incredible to listen and learn from your lectures, they are compact yet so comprehensive, thanks again ❤

[@ejch4896]

Thank you for putting these videos out here for the whole world to learn for free ❤️

[@shaziaali6276]

Thank you for taking the time to make these videos. They're so informative and make learning easier

[@bluewater5463]

You’re the best brother, thank you so much for every video

[@nicksondado4393]

THANK YOU FOR YOUR LECTURES

[@syedmaroofshah5603]

Thank you so so so much ❤️❤️❤️ ... For providing us these incredible lectures...

[@drsohailzahir2837]

Been missing ur lectures.... welcome back.... Great job... much appreciated... ❤❤

[@preet8550]

so appreciative of this content.. God bless you!!

[@aparnapearlypink7273]

Thankyou so much for the incredible lecture ! Waiting to learn more from you doctor …Love ur lectures ❤

[@wambam3]

Absolutely love your videos! I have medically induced hypothyroidsm, it's been so hard to try and explain to new GP's that I need their help rather than them just insisting i go to my psychiatrist - Educating myself with your videos has definetly helped me better understand my body and what i can do to help it. Also super helpful when thinking about it in a veterinary context too! Ps. Also love seeing why my doctors had me going to all these different tests haha

[@_equanimity_]

Huge fan of your videos, thanks for what you do!

[@anamariaguzi]

Thank you so so much. you explain things so well!

[@valviv]

Great video! Also love the second sleeve!

[@khushkothari7270]

Outstanding integration of concepts !!!!!😊

[@claireamba8784]

Thank you soooo very much tutors of Ninja nerd, you guys are lifesavers....

[@chodito12345]

You are amazing. Have this 74 y/o with elevated TSH and T 4. Was thinking it could be secondary

[@z.nurkulege5898]

thank you. great job.

[@user-uo4zd3ku1h]

Thank you for the lecture ❤

[@brofred7623]

Thank you so much Ninja nerds

[@hammbaby]

great video, love the energy, like you got good levels of t3 and t4.

[@muqtarjamaegal6071]

What a legend you are
I am taking deep breath
To thank you

[@malmarzouq7]

Thank you so much very useful :)
Wondering when the notes of this will be posted on the website. They massively help me with studying.

[@ssssv7929]

As always brilliant

[@Janayoonie98]

Thank you!

[@vvmakoubou1344]

I have treated my conditions with the supplementations of vitamin d3k2, copper and zink and the conditions went into remission, including a reduction in diabetes

[@nickidarrington7488]

🐐🐐🐐🐐 G.O.A.T.
This was so helpful. Thank you!

[@sajiruddinsk8129]

Very good.

[@krishnasachan3768]

thank you sir

[@Shwenistorage4]

Thanks

[@Mitochondria527]

Excelente

[@noRbody1]

"chilling bro" got me 😂😂😂
You guys are legends👏👏👏🙌🙌🙌

[@Zion-1610]

Thankyou sir

[@amena1144]

Thanks ❤

[@Bykeekee]

Thank youuuu

[@user-un7pj4cd1u]

Our superhero❤

[@ngoudasylla7871]

thanks so munch

[@kipkipour4507]

Thank youuuuuuuuuu

[@khalilr544]

Thank u kingg🎉🎉🎉

[@sanjith1179]

I'm pratheesh from india( Tamil Nadu).big fan of you sir. Say one hi sir.

[@dr.sanjeevkumrawat9666]

Great 👍🏻

[@dvperez14]

Great!

[@anassoufan6944]

You are the best

[@josephryan3707]

the way I LOL'd with the way u said the neurons were "just chillin broo"

[@lucabertok]

Another great lecture :) Thank you NN 😁
ps Schrute Farms.. awesome 😅

[@woodrowchavarria1163]

Vey good exponent

[@sajjadtalib2380]

Legend 🫡🫡

[@Ali_n21]

Thank you prof.
Please, I have a question about pretibial myxedema.
Is it specific for Graves’ disease? Or does it occurs in other conditions like hypothyroidism?
Because I was reading it and just mentioned in Graves’ disease

[@cabdimalikcadde8991]

Yes both hypo and hyper (graves ) can have pretibial myxedema bc of
in graves
TSHrAb increase sensitivity of TSH to other organs like fibroblasts thyroid adipose tissues then pretibial myxedema forms
In hypothyroidism
TSH Is high and acts these organs ⬆️ and couse pretibial myxedema
I hope its useful 🫡

[@davidaksa]

Is it possible to talk about a little physiology before you delve into the disease itself? Like you would do in the retired videos. For example, talk about how TSH is produced and its function. It used to tie the entire thing together beautifully. :)

[@hannahmurray6764]

There is a physiology video in his earlier lectures with hos TSH is produced

[@enaams7937]

Legend

[@drsnigdhatripathy7128]

Pretibial myxoedema occurs in hyperthyroidism

[@eaf3782]

Postpartum thyroiditis is likely to be transient if only occurs once. But if it occurs after successive pregnancies/postpartum periods, each occurrence makes it less likely that full thyroid function will be restored.

[@deivaruggio2916]

WOW!

[@shaimaa1611]

34:00 I’m dying 😂😂😂😂
Thank u ❤

[@ouhouissmed]

chillin bruh

[@michaelthiab]

The king has made his return
I have a question if anyone could answer, why does the DIASTOLIC bp rise in case hypothyroidism?

[@jordang8317]

Double check this because I’m not a med student but I think it probably is due in part bc hypothyroidism reduces renal flow which results in more fluid retention & therefor higher overall blood pressure (bc there is more fluid in the system). Also I think they have more salt too which also increases water retention and results in increased overall pressure

[@NizakatShirzai]

These videos have a note.

[@ElitecharismaQ8]

🙏

[@akbaraulya5330]

i want a Z3

[@samaammar5522]

❤❤❤

[@priscillamorenocardoso]

❤❤❤❤

[@user-ls7yi9ck1j]

💪💪🙏

[@ShivamSoni-ol3rw]

5:57

[@barzykawa]

❤❤❤❤❤❤❤❤❤❤❤❤❤

[@loyayloa]

[@kassemmagtary9299]

I'm psychiatrist

[@MayaCatz]

Thank you so much !!! Love the shit by the way !!! Fact. Bears eat beets

[@esmaguvelioglu3608]

I really like your videos but if you can talk a little bit slower that would be great 😂

[@user-bu9mk5hd1y]

💯🥷💯🥷💯🥷💯

[@brucephilip8289]

Schrute farms

[@sosanasalama1145]

I pray to god to remove all this tattoos

[@ngoudasylla7871]

thanks so munch

[@GHADA-gy7hp]