Pharmacology and life cycle - Malaria (Antimalarials, pathophysiology, treatment)

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  • เผยแพร่เมื่อ 19 ต.ค. 2024

ความคิดเห็น • 171

  • @d1ks4u
    @d1ks4u 4 ปีที่แล้ว +25

    YO THANK YOU - this cleared a lot up. my pharm lecture slides were cancerous to look at for this topic

  • @dr.beshie_sonereveluv3709
    @dr.beshie_sonereveluv3709 2 ปีที่แล้ว +17

    Also Quinolones are antibacterial drugs classified as DNA gyrase Inhibitors. They are different from Quinines. Thank you for this video, very helpful!

  • @DJMichael_95
    @DJMichael_95 9 ปีที่แล้ว +22

    Armando man, you have inspired me to make my own youtube channel for tutoring thank you man

  • @cfbray
    @cfbray 3 ปีที่แล้ว +3

    In sub-saharan Africa right now and this was extremely helpful. Thank you!

  • @chemicalmistry1905
    @chemicalmistry1905 6 ปีที่แล้ว +39

    Armando, you should actually get some pdf of your drawing which would help us for the last minute revision... Do think of this.
    I Liked ur video.
    I acutually njoy ur video's and don't even feel boring

  • @shibanichand8629
    @shibanichand8629 4 ปีที่แล้ว +2

    Armando ur teaching with ur diagrams are superb...plz give d pictures of them.... it's very smart for us to remind...think on it dear....

  • @kkdubey4
    @kkdubey4 5 ปีที่แล้ว +5

    Thanks. I have malaria. Will take medication from today or tomm after showing the reports to doctor.

  • @aushaddad4352
    @aushaddad4352 5 ปีที่แล้ว +31

    Hey Armando, small correction in your video, the product produced from Heme is called Hemin ( which is ferriprotoporphyrin IX) and not Hematin (they differ from each other)
    and Thank you for the video, really helpful !

    • @Yash_Pardeshi
      @Yash_Pardeshi 2 ปีที่แล้ว +5

      Ya thats what i was thinking and also the quinolones is wrong. it should be Quinolines not Quinolones.

    • @s.a4243
      @s.a4243 ปีที่แล้ว

      *quinines

  • @drashtimistry1090
    @drashtimistry1090 5 ปีที่แล้ว +4

    I got perfectly understood after seeing this video...it is very helpful for the quick revision....you are a great tutor man!!!

  • @tripowerpuff
    @tripowerpuff 3 ปีที่แล้ว +2

    Thanks so much for helping me make my presentation amazing!! :) By understanding the material I created some powerpoint animations explaining how the drugs work. Continue what you're doing!

  • @ericochoa5784
    @ericochoa5784 8 ปีที่แล้ว +10

    This was a great video to better understand the malarial life cycle, thank you! I actually took Chloroquine in the past when I was volunteering in the Carribbean a couple years back. It gave me some pretty nasty side effects.

    • @nancyarchibald9095
      @nancyarchibald9095 4 ปีที่แล้ว +1

      What kind of symptoms did you experience??

  • @SandileMntambo
    @SandileMntambo 8 ปีที่แล้ว +2

    Great Work Armando!!! (All the best on your career.)

  • @preshitapathane2733
    @preshitapathane2733 7 ปีที่แล้ว +3

    Big thank you to you
    Your video has literally saved my life i dont know how many times
    Big big thanks

  • @gramtvafrica
    @gramtvafrica 2 ปีที่แล้ว +1

    After 7 years, it's still useful

  • @simipiwal4473
    @simipiwal4473 4 ปีที่แล้ว +1

    I've a viva now so I went thru ur vid its just🤘👌🤩😍ur explanation got buried in my brain😇😇

  • @chessgold8768
    @chessgold8768 ปีที่แล้ว +1

    Nice but please give the full screen at the last to take screenshot..

  • @tiandrosmarikay3028
    @tiandrosmarikay3028 4 ปีที่แล้ว +1

    Your videos have helped me alot through my medical studies. 💪🏾😎💯

  • @meouby2
    @meouby2 10 หลายเดือนก่อน

    Hi im from 2023 , this help me in preparation for my malaria presentation so much . Tqvm u deserve many likes

  • @BackbenchersRevolution
    @BackbenchersRevolution 7 ปีที่แล้ว +1

    cannot thank you enough

  • @kasojuvamshi7926
    @kasojuvamshi7926 8 ปีที่แล้ว +5

    THF itself is not used in the synthesis of thymidine,it acts as methyl donor in the form of N5-N10 methylene THF for the conversion of d-UMP to d-TMP.

  • @annecapote869
    @annecapote869 9 ปีที่แล้ว +29

    It's scary how much the microbes have mutated to resist our drugs to fight them.
    Btw, your videos are very informative 👍🏻

    • @memoofjacoboarbenzjuanarev9724
      @memoofjacoboarbenzjuanarev9724 4 ปีที่แล้ว +1

      More most of them are basic build especially viruses. But it comes that you can make it in evolution if either you reach for more to make things suitable for you or go for the basics and mastering them.

    • @kayder08
      @kayder08 3 ปีที่แล้ว

      Thank you for the video. really has clarified very astutely yet simplistic, specifically in regards to the life cycle of the parasite -causing malaria

  • @sakinahm.ramadhaniah6165
    @sakinahm.ramadhaniah6165 8 ปีที่แล้ว +2

    really thankyou for all of your works in those videos, it help us alot as medical student to understand many subject, i really appreciate that:)

  • @innocentamechi884
    @innocentamechi884 4 ปีที่แล้ว +1

    God bless you for this.

  • @noorelbackush9824
    @noorelbackush9824 หลายเดือนก่อน

    I am noticing a reoccurring theme of this man having difficulties with writing out the letter i. I was seeing it as a Z the entire time and it maybe took me a good two mins of staring at it to notice that this man was trying to write the letter i. Either way, great video thank you for sharing

  • @tubaafxal6102
    @tubaafxal6102 5 ปีที่แล้ว +2

    Thank you. It helped a lot😊

  • @praveenkumar-sl8hb
    @praveenkumar-sl8hb 4 ปีที่แล้ว +1

    May you please make the video on antitubercular drug and mode of action

  • @lucyebunu2695
    @lucyebunu2695 หลายเดือนก่อน

    This is soooooo helpful. I really love your channel. Thanyou

  • @lindacarter4543
    @lindacarter4543 9 ปีที่แล้ว +1

    Excellent, I now understand the Malaria cycle.

  • @lindacarter4543
    @lindacarter4543 9 ปีที่แล้ว +1

    Beautiful infectious stage diagram.

  • @mymuslimsoul8149
    @mymuslimsoul8149 4 ปีที่แล้ว +1

    Very well explained Hats off to you sir👏

  • @pavanidea9972
    @pavanidea9972 9 ปีที่แล้ว +2

    awesome videos! u made my revision so easy. very helpful indeed

  • @milandahal9152
    @milandahal9152 6 ปีที่แล้ว +1

    Please make lecture for antifungal drugs .... your videos are very useful ..thankyou

  • @ziphomadolwana8736
    @ziphomadolwana8736 8 ปีที่แล้ว +1

    You the best man ...thank you very much,your videos keep helping me

  • @santoshprasad.8004
    @santoshprasad.8004 4 ปีที่แล้ว +1

    Thnxu from india 🇮🇳🙏

  • @zas881
    @zas881 5 ปีที่แล้ว +1

    You are awesome. Thank you

  • @chucknorrislife
    @chucknorrislife 5 ปีที่แล้ว

    While the information you stated is correct, the information lacks details. While the rupture of erythrocytes coincides with clinical manifestations it is the recruitment of pyrogenic and inflammatory cytokines that causes the clinical manifestations (irregular fever) such as TNF alpha and IL-1 plus spleen sequestration of abnormally infected erythrocytes (splenomegaly).

  • @jeneseJonEs
    @jeneseJonEs 8 ปีที่แล้ว +2

    you have a vivid imagination! Thanks !!

  • @manishathakur337
    @manishathakur337 4 หลายเดือนก่อน

    Aesome awesome, no words for all your hard work

  • @carterwilliams4041
    @carterwilliams4041 6 ปีที่แล้ว +1

    Thanks a million for this video. Very helpful

  • @efosalander7782
    @efosalander7782 8 ปีที่แล้ว +2

    Very helpful, thanks. Pls, wud like u to create a video on antimicrobial chemotherapy. Thanks alot I enjoyed the video.

  • @mansourabdulshafea8647
    @mansourabdulshafea8647 6 ปีที่แล้ว +1

    Great Work mate

  • @nandinijassal5062
    @nandinijassal5062 3 ปีที่แล้ว +1

    Really helpful 👍

  • @mekdestamiru6931
    @mekdestamiru6931 4 ปีที่แล้ว +1

    Incredibly done!
    I appreciate yu much!

  • @williamgarangawan3890
    @williamgarangawan3890 2 ปีที่แล้ว

    The teaching was very interesting

  • @videoahmad9364
    @videoahmad9364 5 ปีที่แล้ว +1

    Nice video sir
    We need more videos sir
    On pharmacology

  • @josephfolajimi9646
    @josephfolajimi9646 5 ปีที่แล้ว +2

    where did you get the sources??

  • @lifewithsomari3923
    @lifewithsomari3923 4 ปีที่แล้ว +1

    Wow this was soo good

  • @sarathibiswas5790
    @sarathibiswas5790 4 ปีที่แล้ว +2

    Wonderful explanation. Thanks

  • @marlonliancondes5506
    @marlonliancondes5506 7 ปีที่แล้ว +5

    Hi! Very good and impressive video/lesson once again Mr. Armando!
    But I just would like to ask if it really is Artemisin or is it Artemisinin??
    Thanks!

    • @icnp
      @icnp 4 ปีที่แล้ว +3

      no, its a mistake... is Artemisinin

  • @scottyjoeful
    @scottyjoeful 5 ปีที่แล้ว +1

    Thank you!

  • @anonmikey
    @anonmikey 3 ปีที่แล้ว

    thank you so much mr hasudungan

  • @alole3210
    @alole3210 8 ปีที่แล้ว +18

    good job but there were some mistakes
    1. you said oocyte but it's Oocyst
    2. in 11:52 you said that primaquine is contraindicated for people with G6P deficiency while it's Glucose 6 phosphate dehydrogenase deficiency (G6PD deficiency )

    • @DrArjunKataria
      @DrArjunKataria 8 ปีที่แล้ว +5

      read your 2nd point.
      its foolish

    • @zahera6
      @zahera6 8 ปีที่แล้ว +2

      +Arjun Kataria the second point is totally right ... it's a small mistake no problem with that ...

    • @lajulaju2939
      @lajulaju2939 7 ปีที่แล้ว

      A1 A1 u

    • @nystagmus
      @nystagmus 7 ปีที่แล้ว

      A1 A1 i think you are right. I got the 2 classes mixed up

  • @rakibulalam952
    @rakibulalam952 7 ปีที่แล้ว +1

    thanks... it's really helpful for me

  • @studentofmedicine355
    @studentofmedicine355 8 ปีที่แล้ว +1

    superb video..... very useful..... loved it 😍

  • @purnendupronoy7902
    @purnendupronoy7902 4 ปีที่แล้ว +1

    I dont need any soft copy man! I draw myself all of ur diagrams!! U r genius man

  • @wes4942
    @wes4942 4 ปีที่แล้ว +2

    hold on gonna cry for a bit

  • @mohammadhassanain8483
    @mohammadhassanain8483 8 ปีที่แล้ว +1

    thnks sir your lectures are very helpful for us

  • @erikartur4721
    @erikartur4721 9 ปีที่แล้ว

    very good lesson

  • @JesahEmmanuel
    @JesahEmmanuel ปีที่แล้ว

    Thank you 😊 Extremely helpful

  • @xBassel92x
    @xBassel92x 9 ปีที่แล้ว +1

    Man, you are 2 months late. A i had the pharmacological malaria treatment about a month and a half ago, this would've been really useful. Of course thanks anyway, keep the great job.

  • @yousrakhan9620
    @yousrakhan9620 4 ปีที่แล้ว +1

    Omg you are a blessing 😍😍

  • @suhasd2074
    @suhasd2074 4 ปีที่แล้ว +1

    Thanx man

  • @danielvictormusinguzi
    @danielvictormusinguzi ปีที่แล้ว

    Very informative, thank you.

  • @ilaila3504
    @ilaila3504 ปีที่แล้ว

    The thing that confuses me is that the vacuole looks like it's inside or smaller than the merozoite - but the merozoite is inside the vacuole i think? as it surrounds itself with the vacuole which comes off the rbc membrane. So when i watch this video i keep thinking the merozoite is the circle in the middle but it's not!

  • @nedgey
    @nedgey 4 ปีที่แล้ว +1

    Amazing.

  • @homoeomedica816
    @homoeomedica816 2 ปีที่แล้ว

    Very nice explaination

  • @LOLA-yj9rr
    @LOLA-yj9rr 2 ปีที่แล้ว

    This is wonderful

  • @Robertmacmedia
    @Robertmacmedia 4 ปีที่แล้ว +2

    Thanks Armando great information,I travel to Thailand and Vietnam 8 months out of year,I’ve been told I have a sign of anemia and my arm bruises and bleeds on simple contact just started within a year sometimes feels like I got the flu I’m always tired, any information or ideas to help me or guide me in the right direction to find proper DR Thank you very much Robert

    • @dinahmwangi7955
      @dinahmwangi7955 4 ปีที่แล้ว

      Hi Robert. That region has a high prevalence of P. Vivax which produces benign tertian malaria which is rarely fatal.It has exoerythrocytic forms and can persist for years.A molecular test would be preferrable.

  • @Lubn_1486
    @Lubn_1486 4 ปีที่แล้ว +1

    Beautifully concised n informative! Awesome video! 👌👌

  • @methodjm
    @methodjm 8 ปีที่แล้ว +3

    Thank you man.. your lecture is helpful in my studies

  • @hardikpatel.
    @hardikpatel. 4 ปีที่แล้ว +27

    Hydrochloroquine ✅✅. Stay strong .

  • @josephfolajimi9646
    @josephfolajimi9646 5 ปีที่แล้ว +1

    where do you get your sources from?

  • @bentayahamza5459
    @bentayahamza5459 4 ปีที่แล้ว +1

    wonderful explanation . i have a question what is the interest (mechanism) of Chloroquine in the treatment of Corona virus

  • @DANTHETUBEMAN
    @DANTHETUBEMAN 6 ปีที่แล้ว +1

    how can Malaria be so intelligent, " it developed a pump to remove medication from the cell" ,, this shows the polymorphic of these things, it is like fighting 5 forms of Malaria all at once. great vid.

  • @masoorahamir4132
    @masoorahamir4132 6 ปีที่แล้ว +1

    You don't know how easy you made it for me 😍😍 Thankyou Thankyou so much❤

  • @muthuselvank3953
    @muthuselvank3953 7 ปีที่แล้ว +1

    thanks dude

  • @dipannitabosudhar
    @dipannitabosudhar หลายเดือนก่อน

    Thanks a lot Sir.

  • @galmayhealthcare552
    @galmayhealthcare552 6 ปีที่แล้ว +1

    Great job but lumefantrine is not in the class of quinolone

  • @douglassbarboza9466
    @douglassbarboza9466 9 ปีที่แล้ว +1

    why use chloroquine for systemic lupus erythematosus??

  • @catherineakinwale
    @catherineakinwale 3 หลายเดือนก่อน

    Thank you 2024❤

  • @leejones3155
    @leejones3155 4 ปีที่แล้ว +27

    Every CDC employee is learning new things watching this video 😂

  • @TheJulienSorel
    @TheJulienSorel 5 ปีที่แล้ว

    You're the best!

  • @ELISA-in7hq
    @ELISA-in7hq 5 ปีที่แล้ว +1

    thanks alot but about quinolones, can, i was wonderling if hematin can be used to cure malaria

  • @alisha1678
    @alisha1678 4 ปีที่แล้ว +2

    Please sir , continue all the microbiology lectures, I am literally very poor in microbiology, and its very irritating subject. 🙏🙏

  • @edwinvilcapajares1975
    @edwinvilcapajares1975 8 ปีที่แล้ว +1

    I like your Class

  • @jonahfox1138
    @jonahfox1138 5 ปีที่แล้ว +2

    Artemisnin, not artemisin

  • @AbdulHakeem-vz1he
    @AbdulHakeem-vz1he 9 ปีที่แล้ว +1

    thankyou
    but I wan't another favor plz upload your videos on utorrent because in our counrty for youtube we use proxy and it's difficult to watch your videos online because of buffering

  • @shazaabdel-azeem6460
    @shazaabdel-azeem6460 ปีที่แล้ว

    thanks

  • @zapy422
    @zapy422 7 ปีที่แล้ว

    Thank you for this video

  • @tracyevans-gilbert1810
    @tracyevans-gilbert1810 8 ปีที่แล้ว

    nice work. love you

  • @varuntej5175
    @varuntej5175 8 ปีที่แล้ว +1

    Thanks a lot so helpable...

  • @lestaroberts2189
    @lestaroberts2189 ปีที่แล้ว

    thank you for this is amazing

  • @user-mj7hj5oq2j
    @user-mj7hj5oq2j 10 หลายเดือนก่อน

    What about artesunate?
    Was waiting fortht

  • @aparnakhoptikar1113
    @aparnakhoptikar1113 4 ปีที่แล้ว +1

    It's 'Hemin', not 'hematin'.

  • @lorenzoernestopazsantos178
    @lorenzoernestopazsantos178 9 ปีที่แล้ว

    Wow, es grandioso. Me gustó mucho tu video.

  • @jigarsolanki2499
    @jigarsolanki2499 4 ปีที่แล้ว

    Thanks sir

  • @hafeezullah6740
    @hafeezullah6740 4 หลายเดือนก่อน

    How can we get notes of these

  • @rajangautam3403
    @rajangautam3403 7 ปีที่แล้ว +6

    as far as i know lumefantrine is amino alcohol. and you are saying that lumefantrine is a quinolone.... please make it clear...... and your all videos are awesome otherwise. thanks

    • @shadyplays2006
      @shadyplays2006 5 ปีที่แล้ว +1

      i doubt any of these drugs fall in the category of Quinolones. Quinolones are derivatives of nalidixic acid and are bactericidal agents. Not antiprotozoal

  • @kaputolloyd5537
    @kaputolloyd5537 ปีที่แล้ว

    Thanks you 🙏

  • @muhammadbilalmirajdin3764
    @muhammadbilalmirajdin3764 5 ปีที่แล้ว +5

    My pharmacology teacher just stole everything from this video 😃😬