Why do antidepressants take so long to work?

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  • เผยแพร่เมื่อ 15 ก.ย. 2017
  • Buy "Memorable Psychiatry," "Memorable Psychopharmacology," and "Memorable Neurology" on Amazon! memorablepsych.com/books
    For someone struggling with depression, being told that an antidepressant will take weeks or months to work can be frustrating. Yet this delay is also the key to these medications' ability to help. Find out why in this video.
    Papers that inspired this talk:
    Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action. www.ncbi.nlm.nih.gov/pubmed/1...
    How do antidepressants work? New perspectives for refining future treatment approaches. www.ncbi.nlm.nih.gov/pubmed/2...
    All music and video are under the public domain with the following exceptions.
    Creative Commons license:
    Background Music: "Divider" by Chris Zabriskie
    Clouds Timelapse by Vincent Wolf
    Corporate Building and Clouds Time Lapse by Beachfront
    Car Driving Through Tunnel Slow Motion by Simon Waldock
    Medical Pills on White Surface by Videvo
    Young Couple Sat in front of Detroit Cityscape by Videvo
    Clock Face Timelapse by Videvo
    Panning Around Woman Watching Waterfall by Videvo.net, Kiril Dobrev
    LA Mountain Sunrise by mikesteinkamp
    Lady Overlooking Ocean by Videvo
    Rain on Window Rack Focus by AHFilms
    Ice Cream Melting by mitchp
    Starting Stopwatch by Videvo
    Iraqi Militiaman at Sabaa Nissan water plant in Baghdad, Feb 2003 by Christiaan Briggs
    Close Up of Watch Face by Videvo
    Child Putting on Shoe by RGB Parade
    Germs Animated Background by Beachfront
    Scientist Using Microscope by Videvo
    Digital Clock Chaotic Time Lapse by Beachfront
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    Single use commercial license, purchased:
    Patient At A Reception At The Woman Doctor by mr_NightMan
    Taking Pills by Pressmaster
    Man Talking With His Therapist At Therapy Session by kopitin
    Infusion by tuomatu
    Unclear copyright status, but believed to be in the public domain:
    The Human Brain by Encyclopaedia Britannica Educational Corporation

ความคิดเห็น • 483

  • @thesummerland6165
    @thesummerland6165 4 ปีที่แล้ว +436

    one of the worst illnesses to have, invisible and impacts everything

  • @luxinfinite
    @luxinfinite 2 ปีที่แล้ว +291

    Antidepressants changed my life. I inherited depression from my father’s side and I always lived with functional depression, and I thought that was normal. Until recently that I started taking medication for it, I feel my whole thought process changed, and I do think I have more clarity and can make better decisions and be in peace with my emotions

    • @ayubsaleh6172
      @ayubsaleh6172 ปีที่แล้ว +2

      What med you’re taking please?

    • @deltaairlinescaptain5912
      @deltaairlinescaptain5912 ปีที่แล้ว +1

      Very happy for you 😊😊😊😊

    • @skrd851
      @skrd851 ปีที่แล้ว +1

      Which antidepressant did you take ?can you inform me please..

    • @luxinfinite
      @luxinfinite ปีที่แล้ว +7

      @@skrd851 venlafaxine, it has double effect as antidepressant and anti anxiety, cuz I also have anxiety disorder

    • @PhoeniX-vz6zj
      @PhoeniX-vz6zj ปีที่แล้ว +6

      Ur comments just gave me hope. Already trying to get a place

  • @provost5752
    @provost5752 4 ปีที่แล้ว +424

    Learning to process being happy takes time when you've spent a lifetime being unhappy.

    • @markgaskell5370
      @markgaskell5370 2 ปีที่แล้ว +6

      This is a brilliant and accurate comment

    • @edward5247
      @edward5247 2 ปีที่แล้ว +4

      expecially with dysthymia, i had dysthymia since i was 12 and i am 25 now, it ruined my whole young age... just now i am on zoloft and starting to see joy

    • @hemalatagusain5616
      @hemalatagusain5616 2 ปีที่แล้ว +1

      @@edward5247 brother how much did you take it..... Do it change something in you

    • @therealalmightyloaf3285
      @therealalmightyloaf3285 2 ปีที่แล้ว +2

      Although I’m only 15 it’s quite hard to process happiness, after you’ve spent almost all your conscious life with ADHD and depression thinking “Yeah this is what happiness feels like.” And really it’s extremely temporary and then after that maybe week of enjoyment (not happiness) you feel hollow and think there’s something wrong with you. You think is what I’m feeling normal? Why does everyone look so accomplished and prideful? You get sadder and sadder and realize that things that once brought you joy don’t do anything for you anymore yet you still want to do them. You realize this and wonder, is this depression? You start to doubt yourself and think “No, I’m probably just making it up for attention.” :(

    • @Nobody13906
      @Nobody13906 ปีที่แล้ว

      Love this i thought i was the only one who thought that

  • @choops2373
    @choops2373 ปีที่แล้ว +57

    actually. i felt a difference after the first night taking setraline 50mg. been 2 weeks now and the negative thoughts are gone. ive been suffering with depression and suicidal thoughts for the last 10+ years. i finally have a calm mind to live my life. please if anybody reads this, please never give up. get help and do whatever it takes to get better. it is possible. no matter how long you've been suffering, it can be helped. best of luck to all of you :)

    • @MrJangofett123456
      @MrJangofett123456 ปีที่แล้ว +3

      I just got prescribed setraline for my anxiety the same amount as you. I'm a little nervous about it though. I'm not depressed just have debilitating anxiety lol

    • @choops2373
      @choops2373 ปีที่แล้ว +2

      @@MrJangofett123456 i also have a little anxiety. the medicine is helping with it as well. hope for you the best with your anxiety :)

    • @Bilbojack4
      @Bilbojack4 7 หลายเดือนก่อน

      Thank-you for your message of hope 🙏.

    • @ats-3693
      @ats-3693 4 หลายเดือนก่อน +1

      I also got quick positive results with sertraline for debilitating anxiety, not on day 1 though for the first week it made me feel kind of agitated and a little more anxious, but after 8 or 9 days taking it the side effects stopped and my anxiety level suddenly dropped away to almost nothing, it's such an incredible relief to me I'd actually completely given up on ever feeling relaxed, happy or normal again, now life is good again! 😊

  • @infoharvester
    @infoharvester 5 ปีที่แล้ว +160

    I knew I felt different minutes after taking ssri. I thought that was just the placebo effect - me just hopeful after taking it.
    Thanks for this video

    • @junesilvermanb2979
      @junesilvermanb2979 4 ปีที่แล้ว +2

      en.m.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitor

    • @yankeenobonagu6411
      @yankeenobonagu6411 3 ปีที่แล้ว +12

      well it is the placebo effect, ur not supposed to feel an ssri untill a few weeks but good news is your depression is also just the placebo effect, neither happyness nor suffering is real

    • @royaldaughterofgodholygrai1878
      @royaldaughterofgodholygrai1878 3 ปีที่แล้ว +4

      @@yankeenobonagu6411 then why do we feel it not saying I dont agree

    • @yankeenobonagu6411
      @yankeenobonagu6411 3 ปีที่แล้ว

      @@royaldaughterofgodholygrai1878 i dont know, but you are aware of your depression ur aware of your happyness, your awareness is neither affected by happyness or depression (or fear for that matter)

    • @chgofirefighter
      @chgofirefighter 2 ปีที่แล้ว

      Placebo effect, NO antidepressants works in minutes 😏🤦‍♂️

  • @hedgehodg1203
    @hedgehodg1203 6 ปีที่แล้ว +57

    I'm overjoyed to see that you're still making videos. I found your Psychopharmacology series to be concise and fascinating. The mnemonics that you included make the content impossible to forget. Your latest material has been thought provoking and most informative. Please keep it up.

  • @FBI-tz4vq
    @FBI-tz4vq 3 ปีที่แล้ว +35

    Now this is something that gives me an explanation. This is what makes me understand. I've always wondered and I went to many explanations and I've never really gotten the explanation in the form that I wanted. Just really long words, but this video and the way you put it together with the images and music made me process it. Thank you, you're doing a really good job.

  • @doubleetendre
    @doubleetendre 5 ปีที่แล้ว +9

    Thank you...for your pharm videos, the insights, mnemonics, and dissection of material. Very helpful.

  • @easystreetguns
    @easystreetguns 6 ปีที่แล้ว +7

    Glad to see another great post from you

  • @bluerivers95
    @bluerivers95 4 ปีที่แล้ว +162

    SSRI'S SAVED MY LIFE!!

    • @Mike-rh9zs
      @Mike-rh9zs 4 ปีที่แล้ว +20

      THEY RUINED MINE

    • @ishowspeedaf9986
      @ishowspeedaf9986 4 ปีที่แล้ว +3

      @@Mike-rh9zs why so

    • @Mike-rh9zs
      @Mike-rh9zs 4 ปีที่แล้ว +7

      @@ishowspeedaf9986 gave me ED. Look up PSSD. Only took two pills of Lexapro and then 9 cymbalta 2 months later

    • @derelb504
      @derelb504 4 ปีที่แล้ว +3

      @@Mike-rh9zs PSSD is now officially recognised, so they'll hopefully only give antidepressants to people who really need them. I take antidepressants because I'd be dead without them. Have you thought about asking for a testosterone test? I get ED if I don't use Testogel.

    • @Mike-rh9zs
      @Mike-rh9zs 4 ปีที่แล้ว +2

      @Mathieu FortGay this was 11 months ago everything has cleared still should take that?

  • @Sallyhabib1
    @Sallyhabib1 4 ปีที่แล้ว +9

    your videos are awesome, they deserve way more views. Accurate information, and interesting portrayal of information!

    • @wellofcire
      @wellofcire 3 ปีที่แล้ว

      except when he said her face betrayed loneliness....that was a bit depressing

  • @supDeny
    @supDeny 2 ปีที่แล้ว +38

    When he said “within years” I immediately thought of myself. It took me 2 and a half years to get better . I was on 250mg of Zoloft(highest dose) and Wellbutrin 150 mg . It took me very long to be happy with myself. I am never getting off this medication ever again!!!

    • @nathontailor1352
      @nathontailor1352 2 ปีที่แล้ว

      Do you drink alcohol?

    • @Bubba__Sawyer
      @Bubba__Sawyer 2 ปีที่แล้ว +6

      That's a ridiculously high dose of either let alone both at once. Good Lord....

    • @Syuurp
      @Syuurp ปีที่แล้ว +6

      You must have been going through literal hell to need that high of a dose from both. Glad you’re happier

    • @mentiquebakabila4254
      @mentiquebakabila4254 ปีที่แล้ว +1

      It’s still working?

    • @lookadooka_
      @lookadooka_ ปีที่แล้ว

      Theres no way you took 250mg of zoloft WITH another drug. 250mg of sertralin are already very dangerous for your body

  • @LeChimp-jg6fh
    @LeChimp-jg6fh 5 ปีที่แล้ว +57

    Probably one of the best videos I've ever watched on yt.

  • @andreicotofan3105
    @andreicotofan3105 5 ปีที่แล้ว +4

    Please keep up the great work! Very insightful! I have to listen to this on x1.25 maybe it's just me

    • @sohail16
      @sohail16 4 ปีที่แล้ว +2

      Andrei Cotofan he does talk slow but it’s good b/c people with depression and anxiety can focus better to what he says :)

  • @ShermanT.Potter
    @ShermanT.Potter 2 ปีที่แล้ว +38

    I take an ssri. After a few weeks, it lessened the number of panic attacks I had, the severity of my OCD, and probably lessened the amount of crying. I remember when I would go cold turkey off of it, I would curl up in a ball and ball my eyes out. I'm still very depressed and mostly focus on the negative. But I hardly ever cry now and I'm emotionless to alot of stimuli, things that should effect me don't, or I think about them with a sense of futility. Except anger, that seems to have increased after being on it for a decade. So maybe it turns you into a psycho long term, lol.

    • @ehsanahmed1554
      @ehsanahmed1554 ปีที่แล้ว

      Which ssri you are useing nd dose

    • @ShermanT.Potter
      @ShermanT.Potter ปีที่แล้ว

      @@ehsanahmed1554 Was venlafaxine initially, I think 150mg. Hospital bumped it to 500+mg one time but that had no effect. Switched to sertraline a few years ago, was on 200mg for a while, 150mg most of the time.

    • @Loneranger670
      @Loneranger670 11 หลายเดือนก่อน +2

      It’s called emotional blunting. It may sound like a negative effect, but in a way it helps to limit being constantly consumed consumed by a negative emotional state.

    • @granolagirlGfunk
      @granolagirlGfunk 10 หลายเดือนก่อน

      Please don’t quit anti-depressants cold turkey.
      Most need a slow weaning.

  • @dmtdreamz7706
    @dmtdreamz7706 ปีที่แล้ว +4

    Alienation is the feeling of being isolated or separated from something, often a group or society. It can also refer to the sense of being disconnected from one's own feelings, thoughts, or identity. Alienation can be caused by a variety of factors, including social isolation, discrimination, and the experience of living in a society that is different from one's own values and beliefs. In some cases, alienation can lead to feelings of loneliness, isolation, and resentment. However, it can also be a source of creativity and individuality, as individuals may seek to find their own voice and place in the world.

  • @brandonevershed5362
    @brandonevershed5362 5 ปีที่แล้ว +24

    Good video. Been on anti-depressants, on and off, since 1992. This is very well said.

    • @dwikafebrianto3016
      @dwikafebrianto3016 4 ปีที่แล้ว +3

      Do you still depend on them?

    • @hoffmancz5701
      @hoffmancz5701 11 หลายเดือนก่อน

      @@dwikafebrianto3016it doesn’t cure. It rids off from symptoms

  • @abdulazizalharbi1798
    @abdulazizalharbi1798 4 ปีที่แล้ว +2

    😮 wow ,this video summarized books about depression.thanks man 👨 on this video,i will help millions ♥️♥️♥️♥️♥️♥️

  • @shyaaammeneen63
    @shyaaammeneen63 2 ปีที่แล้ว +7

    Very useful video. The goal should be to take only one ADS of the lowest mg. In life there are only 2 problems--mind and the body. To feel better reduce negative thoughts [overthinking]. Your breathing is closely related to the brain [mind] and gives good relief from stress-anxiety. To relax sit on a chair or lie down, neck straight, eyes closed and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for 5-10-15 minutes or more. Don’t fight your thoughts. With daily practice the mind will relax. No deep breathing needed. Do the practice without any expectations when taking a walk, before sleep, in school, at work, when reading, etc. Like me, make this a lifetime daily habit to have a better life. Reduce negative social media, take morning sunlight walks and avoid constipation as it affects the mind instantly. Best wishes--Counsellor.

  • @lesleylema5141
    @lesleylema5141 2 ปีที่แล้ว

    Thank you for this video

  • @marcelcoetzee7152
    @marcelcoetzee7152 6 ปีที่แล้ว +19

    Very interesting topic. The really tricky part is that my experience with bipolar shows that this is doubtful. The function in bipolar people can change within a day when given these medications but this is due to a secondary system, ( the bipolar switch) but not due to the underlying effects of the medication. The person can switch easily without it anyway, the medication still takes effect in a few months and it may also aggravate the bipolar mixed episodes. This is very important because having the medications work too quickly becomes a serious and dangerous side effect. This seems to disprove part of the theory but it is still notable that CBT is very good at treating normal depression.
    My 2 cents of theory and explanation of this is that it is likely that psychology can cause an issue in the serotonin systems in the brain that is of a neurological nature. This would mean that the symptoms seen are indirectly rather than directly determined by the depressive nature of the person and thus treatable by medication and psychology simultaneously.

    • @MemorablePsych
      @MemorablePsych  6 ปีที่แล้ว +8

      I thought about putting in a brief aside about how this discussion would not apply to bipolar depression, but in the interest in keeping the video short and sweet I left it out. What we know from decades of research is that bipolar depression is a completely different thing than unipolar depression, both biologically and psychologically. Medications that work for unipolar depression do not work (and may even be harmful) when used for bipolar depression, and vice versa. So I don't know if I would agree that the effect of antidepressants on bipolar disorder disproves this theory necessarily; it's probably more accurate to say that this discussion only applies to unipolar depression and that something else entirely is going on with bipolar depression.

    • @justmai2476
      @justmai2476 6 ปีที่แล้ว

      I completely understand where you're coming from, I myself have bipolar disorder. According to Polar warrior, up to 30% of us are initially diagnosed with MDD (me for example) and start taking ADs. But they trigger manic episodes and worsen mixed states, and yet it is still so widely common to be misdiagnosed. I do feel that it completely sets our brains off track when there isn't much balance to begin with.

  • @gautammure
    @gautammure 4 ปีที่แล้ว +1

    Fantastic! Fabulous!

  • @ot4kon
    @ot4kon ปีที่แล้ว +7

    I'm at week 4 of SSRI and still feeling anxious. I'm taking it for Generalized anxiety disorder and OCD.

  • @SmittyWerbenjagermanjensen
    @SmittyWerbenjagermanjensen 6 ปีที่แล้ว +3

    Interesting video.

  • @TheLonelyMoon
    @TheLonelyMoon 2 ปีที่แล้ว +8

    I tried SSRI and SNRI, serotonin based typical antidepressants, for about two years, switched to different drugs within these classes too. NDRI so far has been the most effective. Bupropion and Ritalin, treats my ADHD too
    I don't feel depressed like before, but I still face extreme anxiety, dissociation (DPDR), generalized, and I experience trauma flash back sometimes
    I'm not overly sad, nor do I really experience joy, maybe happiness just isn't for me. It's stable, so maybe it's better this way

    • @lizardman1582
      @lizardman1582 ปีที่แล้ว +4

      NDRIs will reduce your ability to feel pleasure over time and will increase anxiety at least in my experience. SSRIS are better for long term stability AND happiness

    • @MoekoBrooks
      @MoekoBrooks 10 หลายเดือนก่อน

      @@lizardman1582Bupropion is what has worked for me for many years. My depression is thought to be cause by my ADHD, but I do not take stimulants. Several SSRIs have given me suicidal ideation. Those types of beliefs are why I suffered for so long trying SSRIs.

  • @Soopro88
    @Soopro88 2 ปีที่แล้ว +1

    Excellent video

  • @dimitravas6920
    @dimitravas6920 4 หลายเดือนก่อน

    thank you for this video!

  • @EliasEH89
    @EliasEH89 3 ปีที่แล้ว +23

    The most painful illness ever.
    I have OCD + MDD
    I knew i had OCD form age 7, I remember when i walked alone at school and extremely bad ideas and something talk in my mind without begin able to stop it.

  • @parvezkhan-fn2dz
    @parvezkhan-fn2dz 5 ปีที่แล้ว +1

    Interesting video

  • @shb7772000if
    @shb7772000if ปีที่แล้ว +2

    So if they increase serotonin right away, would you be better off taking them in the morning rather than at night?

  • @kristianmuus5672
    @kristianmuus5672 6 ปีที่แล้ว +6

    Please make a video about what happens to the receptors when tapering from an antipsychotic and ssri. Hope you see my message. Thanks mate. Im trying to understand my medication better.

    • @aaronmaloney8282
      @aaronmaloney8282 5 ปีที่แล้ว

      Kristian Muus .. your receptors will down regulate because of a synthetic chemical is replacing the natural chemical your brain produces!

    • @KillBill2114
      @KillBill2114 5 ปีที่แล้ว +2

      Aaron Maloney any info on this? I felt a huuuuuge benefit when I first started taking SSRI - after 1.5 days for about 4-5 months....then it all kind of tapered off. I’ve been on them for probably 9 years and couldn’t reallly tell you what benefit I get today. Miss that early feeling - serotonin was on overload for sure.

    • @dwikafebrianto3016
      @dwikafebrianto3016 4 ปีที่แล้ว +1

      @@KillBill2114 that's why so many people questions anti-depressants' efficacy. If one can improve their depression symptoms by taking supplements such as SAMe, IMO doctors should suggest them as well.

  • @agentblue52
    @agentblue52 2 ปีที่แล้ว +5

    It is not just negative biases that causes all kinds of depression. Genes is one big factor for many.

    • @scarred10
      @scarred10 ปีที่แล้ว +2

      Those genes may be causing those negative biases,nature and nurture interact from conception.

  • @girishsuper8556
    @girishsuper8556 ปีที่แล้ว

    Great hattttssss of sir this video real helpful

  • @mco5383
    @mco5383 4 ปีที่แล้ว +5

    I have a huge positive affective bias. Like I surround myself and am drawn to happy, successful imagery but then get down because of the gap between those images no my current status. I will be happy when i have that lifestyle, that amount of money, that travel experience... so like I don't know how that fits ha

  • @rafaelmch
    @rafaelmch ปีที่แล้ว +5

    Ive been on Pristiq for GAD (general anxiety disorder) for over 6 years now... it took me around 20 days to start feeling better! OH MY GOD.. was it life changing?!

    • @CarlosPerez-mn5gh
      @CarlosPerez-mn5gh ปีที่แล้ว +1

      I recommend the use of psychedelic mushroom it’s all natural and it’s the best to cure anxiety and depression , I can’t remember when last I felt depressed, I was depressed until I got my hands on psychedelic mushroom, I was in pain and confusion now I work effectively and efficiently without worry and fear of the unknown, I get mine from an online vendor that specializes in the growth and sales of psychedelic products

    • @CarlosPerez-mn5gh
      @CarlosPerez-mn5gh ปีที่แล้ว +1

      *Formulah11*

    • @rafaelmch
      @rafaelmch ปีที่แล้ว

      @Mauro Figueiredo I dont know if I'm addicted... but after my first year on it, my doctor took me off it, because i kept telling him i didnt want to be on it forever... 6 months after that I had a major anxiety attack, so i went back to it... and i dont pressure my current doctore to take me off of it... if it happens, ill stop taking it, but know i dont ask my doctor when im gonna stop taking or if i am going to... i really dont feel like I need it anymore to be honest with you, but I'm not gonna be the one trying to stop taking it... if it happens, it happens... if it doesnt, ill just take it... im over it to be honest (over feeling bad for being on it, is what i mean)

  • @francisphillips53
    @francisphillips53 2 ปีที่แล้ว

    Wow.. I learned a lot.

  • @yapikop1142
    @yapikop1142 2 ปีที่แล้ว +5

    Currently on anti depressants, hoping for the best 😇

    • @shyaaammeneen63
      @shyaaammeneen63 2 ปีที่แล้ว +1

      Yapi Cop, The goal should be to take only one ADS of the lowest mg to prevent side effects. . In life there are only 2 problems--mind and the body. To feel better reduce negative thoughts [overthinking]. Your breathing is closely related to the brain [mind] and gives good relief from stress-anxiety. To relax sit on a chair or lie down, neck straight, eyes closed and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for 5-10-15 minutes or more. Don’t fight your thoughts. With daily practice the mind will relax. No deep breathing needed. Do the practice without any expectations when taking a walk, before sleep, in school, at work, when reading, etc. Like me, make this a lifetime daily habit to have a better life. Reduce negative social media, take morning sunlight walks and avoid constipation as it affects the mind instantly. Best wishes--Counsellor.

    • @wowftw120
      @wowftw120 2 ปีที่แล้ว +1

      My advice would be to take them for at least 6 months once you're on them

    • @shyaaammeneen63
      @shyaaammeneen63 2 ปีที่แล้ว

      @@wowftw120 Be careful. 6 months of benzos will make you addicted. If taking ADS stick to the lowest mg which usually does not have any side effects. If you have stress-anxiety read the msg I sent you and do the practice regularly. Best wishes. Sr. Counsellor.

  • @Vicorcivius
    @Vicorcivius 5 ปีที่แล้ว +22

    The reason Anti Depressants take so long is because the entire effect that causes the anti depressing is based on the brain building a tolerance to the anti depressant (At least with SSRI's) this takes at least a month in most people. Usually the actual first effect of anti depressant SSRI (on the first day of taking them) is more depression, oddly.
    They drug manufacturers of SSRIs dont truly understand how they work. They just have a vague idea. Which is insane when you really think about it.

    • @dwikafebrianto3016
      @dwikafebrianto3016 4 ปีที่แล้ว +1

      You have a good point! But the theory on BDNF is very possible even tho I'm not sure it has to be achieved via anti-depressants. I really don't buy it on the chemical imbalance thing on the brain because chemical imbalance is not the cause but symptoms. The cytokine theory is very possible IMO because fish oil can improve depression symptoms but they inhibit cytokines and increase neurogenesis

  • @KeithKillingly
    @KeithKillingly 3 ปีที่แล้ว +3

    I was always more attracted to people not smiling, people that looked angrier or apathetic... I wonder if that'll change after the ssri I just began.

  • @shyamakunda9676
    @shyamakunda9676 5 หลายเดือนก่อน

    I would recommend anyone to do Bhakti Yoga, while being on SSRI or without. Singing Mantras with a lot of people is so enlightening!

  • @pleximanic
    @pleximanic 5 หลายเดือนก่อน +1

    Life is suffering and it makes you beautiful .

  • @binbinky78
    @binbinky78 4 ปีที่แล้ว

    your book is awesome

  • @jer1776
    @jer1776 2 ปีที่แล้ว +15

    Good explanation of the mechanisms behind SSRIs, but while Im happy they work for some, I took two of them years ago for panic disorder/anxiery and they did nothing, where as taking Klonopin for a year stopped my panic attacks almost overnight and kept me panic free for years.

    • @joerobley8469
      @joerobley8469 2 ปีที่แล้ว +1

      Isn't Klonopin a Benzo? Isn't it dangerous to use Benzo's for such a long period of time.

    • @jer1776
      @jer1776 2 ปีที่แล้ว +2

      @@joerobley8469 It can be depending on the individual. I personally think they are over stigmatized because a small minority of users abuses them. I did just fine on .5mg a day, then tapered myself off when I felt I didnt need it anymore.

    • @BillynBertie
      @BillynBertie ปีที่แล้ว

      @@jer1776 Benzos absolutely ruined my early life, not because I abused them, but because medical professionals told me they were a wonder drug and kept me taking more and more in increased quantities as they soon lose their effect on the lower doses. I took them in total for nearly twenty years and getting off them finally was a nightmare and made me extremely ill. Now 40 odd years later, I have been taking Fluoxetine an SSRI, after anxiety and depression following a stroke, but the doctor also insisted I took a 'modern' benzo called Oxazepam. In fact that made me feel like hell again and it has taken me a year to escape from its clutches. I want to eliminate Fluoxetine next, but I think of the two types of drug it is by far the preferable one. I would not recommend my worst enemy to take any form of benzodiazepine.

    • @lukebrusatori4841
      @lukebrusatori4841 ปีที่แล้ว

      Ofcourse a benzo will be more effective.

  • @andrejmaric5955
    @andrejmaric5955 6 ปีที่แล้ว +1

    Very nice video

    • @aaronmaloney8282
      @aaronmaloney8282 5 ปีที่แล้ว

      andrej maric , now educate oneself on the dangers of anti depressants ,& psych meds,. If you had a piece of glass in your foot would you cover it with a bandage ? no of course not,, the horrible truth is that's what all pharmaceutical drugs do , mask problems,

    • @aaronmaloney8282
      @aaronmaloney8282 5 ปีที่แล้ว

      Stay as far away from these drugs if you wanna keep your sanity

    • @alpeke5075
      @alpeke5075 5 ปีที่แล้ว

      Stay away from SSRI S

  • @KillBill2114
    @KillBill2114 5 ปีที่แล้ว +45

    I felt a huuuuuge benefit when I first started taking SSRI - after 1.5 days and lasted for about 4-5 months....then it all kind of tapered off. I’ve been on them for probably 9 years and couldn’t reallly tell you what benefit I get today. Miss that early feeling - serotonin was on overload for sure.

    • @provost5752
      @provost5752 4 ปีที่แล้ว +2

      Try lexapro. It seems some peoples body builds a tolerance to Zoloft.

    • @jdc4316
      @jdc4316 4 ปีที่แล้ว +9

      R Provost it can happen for any of them. Antidepressants are supposed to be that way anyway, making small changes so you can adapt your lifestyle and live a happier life.

    • @zarusaru2179
      @zarusaru2179 4 ปีที่แล้ว +1

      hello, is it still working??

    • @KillBill2114
      @KillBill2114 4 ปีที่แล้ว +7

      KO S I’m on Lexapro 10mg and Welbutrin 300mg. It is really a very subtle improvement - it’s less about making me feel “good” and more about keeping The extreme lows away. I wish wish wish the feeling would have stayed from the beginning but honestly I was taking Paxil and about 40mgs a day / it was probably overload which is why I was flooded with serotonin. Your body regulates over time no matter what...plus weight gain is likely. At the end of the day - we’re probably not supposed to feel “that good” ALL the time...it’s natural to have ups and downs....as frustrating as it is. Just gotta ride the wave. 🤷‍♂️

    • @jdc4316
      @jdc4316 4 ปีที่แล้ว

      Bill Evans there are no highs without the lows.

  • @nascentnaomie
    @nascentnaomie 4 ปีที่แล้ว

    Insightful

  • @delores8383
    @delores8383 6 หลายเดือนก่อน

    Any tips on what to do until it starts working? Feel like I want to do something but at the same time don't want to do anything

  • @papikabron18
    @papikabron18 4 ปีที่แล้ว +1

    can you front load antidepressants?

  • @ralfedsson9258
    @ralfedsson9258 2 ปีที่แล้ว +5

    I'm bipolar and 10 mg of Paxil lifts me out of depression after 2-3 hours. Every time.

  • @wavesnowaves
    @wavesnowaves 7 หลายเดือนก่อน +2

    I looked at the bottles on the table.

  • @shortscut8219
    @shortscut8219 ปีที่แล้ว +1

    Is it normal to have vomiting after starting antidepressants?

  • @kristenhenderson8143
    @kristenhenderson8143 2 ปีที่แล้ว

    man as i thought the meds helped me i was wrong been on seraquel and zoloft for about 6 or 7 years now my memory is horrible i wont sleep if i dont tk the pills idk what to do . im now tking 50 mg i want to go down and get off of this mess

  • @iccedoutpigeon9865
    @iccedoutpigeon9865 2 ปีที่แล้ว +3

    Gonna complete my first week on SSRI. But I still have questions, are there certain foods we have to avoid or can we eat anything?

    • @kifayatullah6761
      @kifayatullah6761 2 ปีที่แล้ว

      How do you feel after 17 days?
      I’m on 11th day of SSRI.

    • @chgofirefighter
      @chgofirefighter 2 ปีที่แล้ว

      @@kifayatullah6761 17 days? Wait 4 to 6 weeks on your medication then most likely you’ll see a difference and ALWAYS talk TO YOUR DOCTOR, not TH-cam. Everyone mechanisms is different that is why these drugs works on everyone differently.

    • @kifayatullah6761
      @kifayatullah6761 2 ปีที่แล้ว

      @@chgofirefighter okay thank you for your priceless suggestion.

    • @RaniaIsmail
      @RaniaIsmail ปีที่แล้ว

      You need to avoid grape fruit juice

  • @Mike-rh9zs
    @Mike-rh9zs 4 ปีที่แล้ว +7

    so is PSSD real? Are my genitals numb forever from SSRI and SNRI medications? on a very very VERY short term basis.

    • @KeithKillingly
      @KeithKillingly 3 ปีที่แล้ว

      are you still having problems?

    • @Mike-rh9zs
      @Mike-rh9zs 3 ปีที่แล้ว

      @@KeithKillingly yes

    • @KeithKillingly
      @KeithKillingly 3 ปีที่แล้ว

      @@Mike-rh9zs Are you older? Could just be age. If you're youngish it should've gone away

    • @Mike-rh9zs
      @Mike-rh9zs 3 ปีที่แล้ว

      @@KeithKillingly happened at 26 now I'm 28

    • @shyaaammeneen63
      @shyaaammeneen63 2 ปีที่แล้ว

      @@Mike-rh9zs How are you now? The goal should be to take only one ADS of the lowest mg to prevent side effects. . Avoid benzos. In life there are only 2 problems--mind and the body. To feel better reduce negative thoughts [overthinking]. Your breathing is closely related to the brain [mind] and gives good relief from stress-anxiety. To relax sit on a chair or lie down, neck straight, eyes closed and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for 5-10-15 minutes or more. Don’t fight your thoughts. With daily practice the mind will relax. No deep breathing needed. Do the practice without any expectations when taking a walk, before sleep, in school, at work, when reading, etc. Like me, make this a lifetime daily habit to have a better life. Reduce negative social media, take morning sunlight walks and avoid constipation as it affects the mind instantly. Best wishes--Counsellor.

  • @carterburton
    @carterburton 2 ปีที่แล้ว +1

    3:24 original video?

  • @BillynBertie
    @BillynBertie ปีที่แล้ว +1

    If SSRIs are so effective in relearning negativity and promoting a more positive view of life, why then is withdrawal from these drugs so very difficult? You might conclude that the new positive attitude would remain even when the actual drug and the levels of seretonin available to the receptors are in decline. But so many people experience depression renewed with an even greater force than before and often abandon the withdrawal from the drug.

  • @richdude8150
    @richdude8150 ปีที่แล้ว

    Seratline work for me but it took me through a shitty worse 8 weeks and also it makes my eyes roll back in a weird way

  • @Indian_Otaku_boi
    @Indian_Otaku_boi 10 หลายเดือนก่อน

    please tell me that, rispond is in the thumbnail

  • @jr-life
    @jr-life ปีที่แล้ว +2

    Just be careful with Serotonin if you have ASD1 because it can cause mania or insomnia ❤

  • @123youbia
    @123youbia ปีที่แล้ว

    Took me 3 days to feel the effects, weird...
    I guess that could be the medicine that is different and now that I see I do indeed think more negative way

  • @69ingpandas76529
    @69ingpandas76529 ปีที่แล้ว

    I can feel it after about an hour

  • @mohammadkhadra2604
    @mohammadkhadra2604 3 ปีที่แล้ว +8

    Zoloft was the most commonly prescribed antidepressant in the USA in 2018 with over 38 million prescriptions.

  • @anishgala1369
    @anishgala1369 ปีที่แล้ว

    Good music

  • @drowsy_mouse8406
    @drowsy_mouse8406 5 ปีที่แล้ว +20

    mdma works in an hour. not only that but 1 use can radically change your outlook long term. should be legal

    • @dwikafebrianto3016
      @dwikafebrianto3016 4 ปีที่แล้ว +7

      But also it should be tightly controlled.

    • @PADARM
      @PADARM 3 ปีที่แล้ว +6

      but at the next day you feel like trash

    • @loadingmikke7451
      @loadingmikke7451 3 ปีที่แล้ว +4

      @@PADARM not if you take a smaller dose. If you keep dropping it throughout the night you'll deplete your serotonin and thats probably why you feel like shit the day after.

    • @brrprr938
      @brrprr938 3 ปีที่แล้ว +8

      Mdma is not a solution, u cant stay on mdma long term or even short term its really gonna mess u up, ur teeth, ur look and so on.. drugs is not a choice even weed

    • @yankeenobonagu6411
      @yankeenobonagu6411 3 ปีที่แล้ว

      @@brrprr938 mdma is good shit, dangerous shit but

  • @hellcome69
    @hellcome69 6 หลายเดือนก่อน

    I've been depressed for 30+ years now. Medication doesn't make me happy, there are no 'happy pills' as people who have no idea what depression is like to claim, they've kept me alive. My sex drive is near completely gone, I don't feel the highs and lows of emotions, but I manage. For me to be able to take care of my pets is far more important than me having an erection or experiencing big feelings.
    Before my mediacations I was unpredictful mentally, I could burst in laughter and then the next minute I could be crying my eyes out. It's not an ideal situation, far from it even with meds I take, but at least I don't think of harming myself or even others anymore. These medications are not for everyone to say the least. It's get some and lose some. For me the undesired effects of these meds is less painful than being without them.
    I don't give a hoot what others think about these physiological problems that I have that effect my mental health. And neither should you if you suffer from this condition. Feeling sad is a normal feeling that happens to everyone, depression is on a whole another level. Take care of yourselves and stay safe.

  • @myresponsesarelimited7895
    @myresponsesarelimited7895 2 ปีที่แล้ว +3

    I felt it straight away but it wore off quickly aswel, until the 3rd week when the dose was doubled

    • @wowftw120
      @wowftw120 2 ปีที่แล้ว

      There's an initial numbing/ europhic feeling but typically only lasts a day or two, that's not how they make you feel day to day

  • @seabird9983
    @seabird9983 4 ปีที่แล้ว +13

    When someone drinks alcohol for the first time, he initially turns away from it. After a while he gets used to it and starts to feel enjoyment. So what happens in antidepressants may be similar to that (an addiction mechanism).

    • @maximilianwieland9304
      @maximilianwieland9304 4 ปีที่แล้ว +6

      That's why antidepressants are not meant to be a long term solution. Antidepressants are meant to stabilize / improve the mood of depressed people. It should always be combined with a therapy sessions with a psychologist in which they learn better ways to cope with their issues or to better understand what causes their depression and how to function in the world even though you feel depressed for long term effects. Some people here say they use them for years but that's not what those drugs are made for.

    • @seabird9983
      @seabird9983 4 ปีที่แล้ว +2

      @@maximilianwieland9304
      In psychiatry, yes, psychiatric medicines have been used for years, as long as the patient feels depressed when leaving the medicine. This logic in psychiatry is the same as that used in all mental illnesses or disordrlers. According to their claims that mental disorders are the result of a chemical imbalance in the brain, and medications correct this chemical imbalance. Personally, I am not convinced of this explanation, even many psychiatrists believe that these are just theories and speculations (the theory of chemical imbalance in neurotransmitters and the like), but they consider psychiatric drugs as the possible solution
      and the available solution now between our hands. Certainly if the patient is able to solve his psychological problems by using Cognitive Behavior Therapy or any Talk therapy with a change in his circumstances of his life, then this is considered the correct and excellent way. But this way cannot always solve mental disorders, which makes the need for medications justified and reasonable. I personally refuse to resort to medicines except for necessity, because they have severe side effects on the patient and deplete the body over the years and their long-term effect may lead to early death or other health problems, this is not to mention the dullness that the medication causes, which makes the patient like a zombie lead an empty, tasteless life. But medication is sometimes very necessary to go through a psychological crisis for a temporary period and is also necessary sometimes for long use when there is no alternative. But my motto is: Do not use the medicine unless necessary..

    • @user-ci7vu7eo9w
      @user-ci7vu7eo9w 3 ปีที่แล้ว

      @@maximilianwieland9304 true.i know 4 people where meds saved their life,one has shizofrenia and wanted to kill himself.his doughter caled the ambulance he was 3 weeks in hospitall.two years of recovery and he now has his own business.true story i know the man

    • @shyaaammeneen63
      @shyaaammeneen63 2 ปีที่แล้ว +2

      @@seabird9983 The goal should be to take only one ADS of the lowest mg to prevent side effects and habit forming. Benzos need to be avoided. Heal yourself. .In life there are only 2 problems--mind and the body. To feel better reduce negative thoughts [overthinking]. Your breathing is closely related to the brain [mind] and gives good relief from stress-anxiety. To relax sit on a chair or lie down, neck straight, eyes closed and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for 5-10-15 minutes or more. Don’t fight your thoughts. With daily practice the mind will relax. No deep breathing needed. Do the practice without any expectations when taking a walk, before sleep, in school, at work, when reading, etc. Like me, make this a lifetime daily habit to have a better life. Reduce negative social media, take morning sunlight walks and avoid constipation as it affects the mind instantly. Best wishes--Counsellor.

    • @k.k.7797
      @k.k.7797 ปีที่แล้ว

      @@seabird9983 Most of this comment seems like unsubstantiated biases with little data suggesting it’s best for patients

  • @athulraj3788
    @athulraj3788 ปีที่แล้ว

    Medicines efect when start?

  • @mossden
    @mossden ปีที่แล้ว +2

    The embarrassment of admitting to depression kept me miserable for most of my life, it was a senseless and avoidable waste of my life . With all of the evidence that antidepressants work there are still some who refer to them as “Happy pills “ and the like making people reluctant to use them

  • @GSOAguitarplayer
    @GSOAguitarplayer 2 ปีที่แล้ว

    On lexapro. Very good cideo

  • @Speydork666
    @Speydork666 9 หลายเดือนก่อน +2

    SSRI are shown to have very little effect in comparison to what they believed at the time you made this video. New reserch also show that ssri can have terrible redrawl symptoms, and that this symptoms earlier was mistaken as "that the mental disease was back, therefore back on the pill", when they actually are redrawl symptoms.

  • @RERTOxCRAFT
    @RERTOxCRAFT 2 ปีที่แล้ว

    Dogs cats and sunsets 🌅 help or sitting at the base of a tree listening to nature focus your ears and see what’s the furthest noise you can hear

    • @wowftw120
      @wowftw120 2 ปีที่แล้ว +2

      But people have to go to work, they can't just spend all their time in such lovely places

  • @kurilomusic2115
    @kurilomusic2115 6 ปีที่แล้ว +4

    Wow.

  • @andyc9902
    @andyc9902 2 ปีที่แล้ว

    I HAVE TAKEN MY PROZAC AFTER 8 MONTHS

  • @nurulradziah9529
    @nurulradziah9529 4 ปีที่แล้ว +2

    been taking them over a month now but i still feel like shit

    • @mussiahsan8719
      @mussiahsan8719 ปีที่แล้ว

      Don't worry. I saw a girl saying her medication worked in 4 weeks or do. She literally spoke how the SSRI is helpful for her to feel peace and be calm. She does not feel anxious any more and can make logical decisions in anxious environment.

  • @mookiecarson465
    @mookiecarson465 5 ปีที่แล้ว +12

    I was drawn to the guy against the railing he seem sad

  • @hypercube2417
    @hypercube2417 21 วันที่ผ่านมา

    Why then do psychostimulants prescribed for ADHD improve mood more quickly than antidepressants? Is it because they increase the amount of neurotransmitters in greater quantities, yes, and antidepressants slightly increase the amount of neurotransmitters and a little bit every day after taking antidepressants and therefore the bad mood then goes away? Probably the difference in time is due to the intensity of the increase in neurotransmitters, that antidepressants a little at each dose increase, normalize and stabilize the number of neurotransmitters, the brain is rebuilt more smoothly, and psychostimulants such as Ritalin increase the number of neurotransmitters at one time more strongly? Is this why antidepressants do not have such a strong risk of addiction as psychostimulants?

  • @Robert_Presto
    @Robert_Presto 5 ปีที่แล้ว +25

    SSRI's over time will change brain chemistry in ways that's not fully understood. I think that's why it takes so long to work.

    • @PeterBerisha
      @PeterBerisha 4 ปีที่แล้ว

      Good thing I gave em up after 9 Days.

    • @PeterBerisha
      @PeterBerisha 4 ปีที่แล้ว +1

      @@ammarqz2080 I made a mistake taking them in the first place.

    • @Lvgan
      @Lvgan 3 ปีที่แล้ว +1

      Peter Berisha I Gave them up after 2 days do you think it changed my brain chem

    • @PeterBerisha
      @PeterBerisha 3 ปีที่แล้ว

      Logan Crump it shouldn’t during that short amount of time and it’s like keeping a shit inside you for two days and then getting rid of it. As for side effects? Nope, none!

    • @zero_meercat8624
      @zero_meercat8624 3 ปีที่แล้ว

      @@PeterBerisha side effects are minimal...

  • @dslime8095
    @dslime8095 ปีที่แล้ว

    Because maybe for one it's not a stimulant and it gradually releases overtime and it reconstructs the brain in a sense if you're seriously depressed and lack a bit of serotonin and not getting enough rest and kind of have a bad diet it may take a bit longer and your metabolism is a factor but idk that's just my thoughts and opinions 💭

  • @samosa60
    @samosa60 4 ปีที่แล้ว +7

    Playing a instrument is best natural way to beat depression & it even releases stress

    • @junesilvermanb2979
      @junesilvermanb2979 4 ปีที่แล้ว +1

      en.m.wikipedia.org/wiki/Musical_instrument

    • @GoldenMushroom64
      @GoldenMushroom64 2 ปีที่แล้ว

      Agreed that’s why I got my piano. I need headphones for it though

    • @brandonmotaramos5810
      @brandonmotaramos5810 ปีที่แล้ว

      Kurt cobain says hello

    • @scarred10
      @scarred10 ปีที่แล้ว +4

      It doesnt treat clinical depression it just gives you a buffer against stress if its something yoh enjoy doing.

    • @jabberwocky4353
      @jabberwocky4353 ปีที่แล้ว

      I'm 52 and practice 3 to 4 hours a day. It relieves depression and stress while playing only. Depression immediately returns when you stop.

  • @thingsnstuff85
    @thingsnstuff85 ปีที่แล้ว

    Sublingual B12 1,000 mcg daily cured my depression. Don’t take too much though and if you start to feel worse stop taking it and only resume as needed

  • @heyitsguillermo7840
    @heyitsguillermo7840 4 ปีที่แล้ว +2

    6:42 WILL YOU LET ME GO?

  • @cathycoppin5682
    @cathycoppin5682 2 ปีที่แล้ว

    About time day made one to work straight away. In stead of people saving for 3 months mucking there life up. What Research has been getting done

  • @edward2364
    @edward2364 ปีที่แล้ว +1

    Anti-depressants Like the one I'm taking right now prozac helps with my anxiety depression and OCD Without this medication I wouldn't function

    • @MrSpock-sm3dd
      @MrSpock-sm3dd 7 หลายเดือนก่อน

      how long until it started working?

  • @BloodClotCryin
    @BloodClotCryin ปีที่แล้ว +1

    No one wants to live in a state of "depressive realism", nor does anyone want to live in a world where everyone sees the world through that lens.

  • @GreenHatPIrate
    @GreenHatPIrate 2 ปีที่แล้ว

    I'm sceptical

  • @smilealways3333
    @smilealways3333 4 ปีที่แล้ว +1

    Chemtrails??

  • @MaiLunatique22
    @MaiLunatique22 ปีที่แล้ว

    so I should keep taking em and eventually it will work

  • @hwago123
    @hwago123 3 หลายเดือนก่อน

    When it says CBT is just as effective I don’t gain much hope for meds :/

  • @user-zs5zd9os9g
    @user-zs5zd9os9g ปีที่แล้ว +1

    The music makes it almost impossible for me to concentrate. Needed to mute and read the auto-generated captions zzz

  • @aliramosgarcia6938
    @aliramosgarcia6938 2 ปีที่แล้ว

    Am on setraline i always think i will never get cured and be happy again!!

  • @MistarZtv
    @MistarZtv ปีที่แล้ว +1

    2:37 the papi on the rail cause 🤭

  • @Candy_Crusher.
    @Candy_Crusher. ปีที่แล้ว

    How much time does it take antidepressants to work?

    • @scarred10
      @scarred10 ปีที่แล้ว

      Bout 2 to 6 weeks after that were thinking of switching.

    • @kareendeveraux1847
      @kareendeveraux1847 ปีที่แล้ว

      Until your brain is damaged enough by those drugs to not recognize the side effects anymore... and then you're addicted. Perfect scam and too evil to believe.
      Inflicting brain damage should be the absolute last resort, not the first reflex.

    • @paintinout3709
      @paintinout3709 24 วันที่ผ่านมา +1

      Up to 8

  • @michaelharned8741
    @michaelharned8741 ปีที่แล้ว

    Vivactil and parnate may work faster than the others

    • @peter7582
      @peter7582 ปีที่แล้ว

      You'll have to go through loads of medicines before a psych will prescribe MAOIs

  • @crystalidx
    @crystalidx 10 หลายเดือนก่อน +1

    Why do we focus only on brain chemistry and not in the quality of life?

    • @mista4323
      @mista4323 10 หลายเดือนก่อน +6

      because you can’t fix your life if you can’t even get out of bed

  • @okidoki3201
    @okidoki3201 3 ปีที่แล้ว +1

    They dont

  • @napa3uma
    @napa3uma 2 ปีที่แล้ว +6

    The reason: clogged liver a.k.a fatty liver.
    That's why when first effects appear you start to gain weight exponentially (especially is you consume refine sugar in any form which is common in people with depression). Also when you change medication, the new one doesn't take long to take effect. It's the same with anti-psychotics.
    Antidepressants do NOT HEAL, they suppress symptoms to make YOUR HEAL (brain rewire, CBT, DBT) easier. Accelerating the healing process is important to reduce prolonged side effects of medication like obesity and sexual dysfunction (especially in adults).

  • @jerrysetlerr770
    @jerrysetlerr770 4 ปีที่แล้ว +1

    This is truth! I would see the exact same things in paintings or pictures , in the catigory of years that it has taken . This is some good rationality . Your hear such stupid shit about meds , I think half of it is the symptoms of depression itself.

  • @Jemalacane0
    @Jemalacane0 2 ปีที่แล้ว +5

    If I were to guess, I would say it's because antidepressants lower dopamine levels which is really stupid and except for a few do nothing with glutamate or GABA. I'm pretty sure a truly great antidepressant will increase dopamine, serotonin, and GABA while reducing glutamate.

    • @1dog915
      @1dog915 2 ปีที่แล้ว

      is there any like that?

    • @Jemalacane0
      @Jemalacane0 2 ปีที่แล้ว

      @@1dog915 I wish.

    • @tesiemarie8942
      @tesiemarie8942 ปีที่แล้ว

      ADHD meds increase dopamine.. So does Wellbutrin

  • @sfrgth457
    @sfrgth457 5 ปีที่แล้ว +8

    Tramadol is the fastest antidepressant. It take just 1 and a half hour to start lifting a depression unlike SSRI'S that take 4 to 6 weeks to work

    • @KS-bx2jf
      @KS-bx2jf 5 ปีที่แล้ว +1

      Miguel Gutiérrez Tramadol?

    • @mickhal1681
      @mickhal1681 4 ปีที่แล้ว

      Victor Oliveira
      I don’t agree
      I take 5 mg srris
      And 50 mg 4 times a week tramadol
      3 days kratom
      No issue
      Keep low dose
      You don’t lose tramadol effects if you keep it at same dose

    • @zimtheinvaderofficial
      @zimtheinvaderofficial 4 ปีที่แล้ว +1

      It really does

    • @kunalsoni1315
      @kunalsoni1315 3 ปีที่แล้ว

      Yes exactly I 100% agree with you. Its difficult to get it without prescription and this drug works for depression

    • @russellconstant1202
      @russellconstant1202 2 ปีที่แล้ว +1

      @@kunalsoni1315 not an Ssirs,,hard to get because they are addictive