Paper spray ionization | soft ionization technique for mass spectrometry

‪@sprucescience‬
Paper spray ionization is a type of ion source that generate ions. This simple and effective ion source uses paper as the primary facilitator that deliver the sample in a controlled manner that produce ions under the influence of an intense electric field. The sample is applied to a piece of paper and solvent is added. When high voltage is applied to the paper that contain the solution, a microscopic jet emerges from the tip of the cone and breaks into a stream of tiny droplets that are electrically charged.
The ions that are generated from the paper spray ionization technique can be coupled to a mass spectrometer for analysis. Such a precision instrument can reveal the molecular composition of the sample. Paper spray ionization technique is advantageous for producing ions from macromolecules because it creates very little fragmentation so its great for the analysis of proteins for instance. Paper spray ionization is a soft ionization technique and it is a variant of electrospray ionization.
SpruceScience.com
Music:
Allégro - Emmit Fenn
Nocturne - Asher Fulero
Wandering Soul - Asher Fulero
Night Snow - Asher Fulero

[@Electrohydrodynamics]

Amazing! Thanks for sharing.

[@Axman6]

Can dripping be avoided by turning the setup upside down?