Immunology Lecture Mini-Course, 4 of 14: Antigen Presentation to T lymphocytes

www.einstein.yu.edu - Immunology Lecture 4 of 14: "Antigen Presentation to T lymphocytes." Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles Michael Chair in Autoimmune Diseases, delivers a mini-course that provides a comprehensive overview in basic immunology for graduate and medical students and for anyone interested in understanding how the immune system works. This mini-course was organized by the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa to provide Sub-Saharan students, research trainees and HIV and TB investigators with a comprehensive course in immunology. (January 2010).
See related lecture slides at:
streaming.einstein.yu.edu/docs...

[@thomasmohamed6218]

I like the way things have been simplified!

[@jojokerus]

Great lecture series. Thanks to the professor and those who filmed and loaded it to TH-cam.

[@muffinman1]

I love his analogies

[@RichardHeitmann]

great lecture,thanx, Richard, Norway

[@ericwintrob4631]

Amazing Lecture!
Eric
Buffalo, US

[@bryankinney1]

thanks so much for the lecture!
I didn't quite understand the tetramer fluorescent method for quantifying T-cells. why do the MHC molecules have to be in tetramer form to interact with the T-cell receptors?

[@nabilakhan6621]

Thank you

[@NavneetSingh-kr5zi]

The content is gr8. It wud be better if the slides were up on the screen while you were talking about them. It is difficult to relate without the slide.

[@RT1327]

In the Class-II locus, each person inherits a couple of genes HLA-DP (DPA1 and DPA2, which encode α and β chains), a couple of genes HLA-DQ (DQA1 and DQA2, for α and β chains), one gene HLA-DRα (DRA1) and one or two genes HLA-DRβ (DRB1 and DRB3, -4 o -5). That means that one heterozygous individual can inherit 6 or 8 Class-II alleles, three or four from each progenitor. (wikipedia)

[@olgak5581]

I wish camera man would be a little more intelligent; how hard is it to guess that when speaker is turned to the slide and describing it, pointing to it, you need to show this slide and not a speaker's profile?

[@TheVishu27]

isn't there should be 12 different types of DP DQ and DR expressing at any given time on MHC type 2 cells? In lecture Dr Harris said 6 different types.

[@lisun1502]

3 from each parent, you will also only pass half to your kids.

[@elMARABIYOCHO1989]

Damn, so the camera dude couldn't have 2 cameras one focused on the slides and one on prof (since he loves him so much), and then upload a video of both?

[@harrisgoldstein2449]

I agree!
If you click on "show more" link above under the Albert Einstein College of Medicine, it will enable you to download a PDF of all of the slides used for each lecture in this series. The Link for this lecture is
th-cam.com/users/redirect?event=video_description&redir_token=QUFFLUhqbnFnTVEzMUZQUXlCSEY0eHI3NkZwUVJOYVJMd3xBQ3Jtc0ttMmNUdjF1MGh1WmE5bXk4WXQ0U0t1Q0oxMm5RY090b0hjMzNXa2VxNGRTNkhNZW1rbndWNG5SS212TUx4eFgwQWo5dXNIeEVQN3RxckwxckdqUURLZjlHTEtuSG9ZcHZFOGE2b2lDZFFRNHJRZmE5WQ&q=http%3A%2F%2Fstreaming.einstein.yu.edu%2Fdocs%2Fconferences%2Fimmunologycourseinsouthafrica%2FL-4-Goldstein-Ag-presentation-by-t-lymphocytes.pdf
I hope this works for you and helps!

[@SukhdeepSingh-wm7bi]

Camera man sucks.... doeant know where and when to focus