006 - Simple blood tests to detect inflammation

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  • เผยแพร่เมื่อ 7 ก.พ. 2025
  • I get asked quite often how someone can find out if they have chronic inflammation. Here are 8 blood tests that your physician can order. If the test results show abnormalities, it is possible that your chronic pain, fatigue, or cognitive issues are due to sustained inflammation.

ความคิดเห็น • 158

  • @deel2435
    @deel2435 6 หลายเดือนก่อน +32

    Blood tests are (from Mr Younger's video):
    high sensitivity C Reactive Protein (hs-CRP)
    Erythrocyte Sedimentation Rate (ESR)
    Serum Amyloid A (SAA)
    Plasma Viscosity (PV),
    Ferritin
    Fibrinogen,
    Interleukin- 6 (IL-6),
    Tumor Necrosis Factor alpha (TNF-a)
    Good luck everyone. Thanks Mr Younger.

    • @johnathanabrams8434
      @johnathanabrams8434 6 หลายเดือนก่อน

      Creatine kinase ?
      Also how can you get these tests that you listed?

    • @deel2435
      @deel2435 6 หลายเดือนก่อน +2

      @@johnathanabrams8434 This list is from the video. Mr Younger lists them out and I've added them to the comments in case anyone is struggling with cog fog or other health issues/disabilities.
      You can ask your GP/healthcare provider to run these tests. Mr Younger talks about this in the video.
      I'm not sure what you're asking with 'Creatine kinase', but I'm not a Dr.

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +1

      @@johnathanabrams8434you can find a lab near you by looking on the internet. If your doctor or healthcare provider won't order look for labs that don't require a doctor's order.

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน

      I have used a lab called Ulta Labs but they are regional and located in the USA. This lab draws the blood but mostly sends the sample to Quest Labs or Lab Corp -these are the two biggest labs in the U.S.

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +2

      @@johnathanabrams8434
      A test for Creatinine Kinase (CK) is used to detect and diagnose muscle damage. CK is an enzyme found in the heart, brain, and skeletal muscles. When muscle tissue is damaged, CK is released into the bloodstream. Elevated levels of CK can indicate:
      1. Muscle Diseases: Such as muscular dystrophy, myositis, or rhabdomyolysis.
      2. Heart Attack (Myocardial Infarction): CK-MB, a specific form of CK, is elevated in the blood after a heart attack.
      3. Trauma or Injury: To muscles from accidents, intense exercise, or surgery.
      4. Other Conditions: Such as chronic kidney disease or certain medications that can damage muscle tissue.
      The test helps in diagnosing the extent and location of muscle damage and monitoring treatment progress.

  • @fibromyalgianational
    @fibromyalgianational 11 หลายเดือนก่อน +26

    You completely made my day with this video! It's something that needs to get shared with providers. I started tracking my blood values because my guess was there was some inflammation going on. Unfortunately doctors didn't feel my markers for ESR and CRP were extreme enough. Higher than they should be but not high enough. I had a lot of symptoms though. Some of the lab companies have "inflammation packages" you can order on your own which is what I did. It's fascinating to look at the various test values and look for patterns once you have enough data. For fibromyalgia, we really need to encourage the providers to run blood tests instead of only relying on the WPI. Thanks again for the video!!

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +7

      Thanks for saying! Yes I think we have to dig in more and figure out the importance of values in this grey zone, especially since most FM and ME/CFS individuals I test are in that exact spot. Those "mildly elevated" values are meaningful. - Jarred Younger

    • @Tinyteacher1111
      @Tinyteacher1111 7 หลายเดือนก่อน +1

      Which tests did you find to be most useful? Thank you!

  • @SteveJohnson007
    @SteveJohnson007 8 หลายเดือนก่อน +10

    The tests are first the two most important ones. CRP, and ESR, and the remaining 6 are, SAA, plasma viscosity, ferritin, fibrinogen, interleukin 6 and tumor
    necrosis factor

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +2

      The CRP is specifically "High Sensitivity CRP" (hs-CRP). There are two different versions of the test and they are used for different purposes. There is what is called a "conventional CRP assay" and that is looking at non-specific inflammatory response. This might be used for purposes of differential diagnosis; examples include in differentiating between Crohn's Disease and ulcerative colitis.
      What Jared Younger mentioned in the video is the "High Sensitivity CRP" test and it is a very good marker for Coronary Artery Disease (CAD) and useful in detecting the presence of or exacerbation of inflammatory processes. Be aware that there are some things that can falsely suppress the test results of hs-CRP. This includes anti-inflammatory drugs like OTC drugs (NSAIDS, salicylates, methotrexate, etc). Likewise, the results can be falsely elevated by things like IUD. If you're looking for CAD markers, falsely elevated results can occur with having a high BMI, smoking (which causes inflammation!), diabetes (causes inflammation!), hypertension, low HDL, high triglycerides, etc. Because those things all contribute to inflammation -so having those will increase inflammation.
      Hope this information helps.

    • @Tinyteacher1111
      @Tinyteacher1111 6 หลายเดือนก่อน +2

      @@Sam-ci8bp I don’t know if it helped the other person, but it helped me!!! Thank you! I have a high risk of having a heart attack, and I think this is elevated on my blood. My doctor didn’t seem concerned, so I figured she knew why I have this. I’m only 97 lbs, and 4’ 9”, so I’m not a likely candidate for this. I’m taking a screenshot of your response! How do you know all this, if I may ask? I had terrible inflammation a few months ago and thought I was going to die! I finally took an antihistamine because I developed severe allergies, and my joint pain went away!

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +2

      @@Tinyteacher1111 I'm doing a dual degree in nursing. I also have health issues so I am always looking and learning.
      I'm glad the info was useful!

    • @Tinyteacher1111
      @Tinyteacher1111 6 หลายเดือนก่อน +1

      @@Sam-ci8bpWell, I wish you well! 🙏 Thank you for the info.
      I have had health issues for 21 years and now I know way more than I want to about toxins!!!
      Good luck!

  • @kathyottkath9994
    @kathyottkath9994 11 หลายเดือนก่อน +7

    As always, very informative and easy to understand.when I listened to Dr. younger present in 2019 ,at the NIH during Advocacy week, I knew he was the researcher giving Fibromyalgia and CFS patients hope.

  • @danielscheerer3032
    @danielscheerer3032 11 หลายเดือนก่อน +5

    Just want to send out my continued appreciation for not only what you are doing but in communicating the pertinent issues publicly. It keeps us hopeful. Cheers.

  • @davidepattibiomed89
    @davidepattibiomed89 11 หลายเดือนก่อน +8

    Great work Jarred. Patient education is the way to go, thank you. Thinking of empowering, with a Pareto mindset as well as inexpensive (auto) testing. Serum Vit D levels, possibly you can do a separate dedicated video, it is a quick win, clinically relevant in autoimmunity, inexpensive, both test as well as supplementation. I would assume long lasting inflammation in autoimmunity drains Vit D reserves. The vitamin is protective against autoimmune triggers, reduces incidence as well as severity, shown in different studies.

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +6

      Thanks! As you have probably seen as well, the Vit D levels are low in over 75% of the FM and ME/CFS individuals we screen (with about 25% of those having severely depleted Vit D). Undoubtedly there are many people struggling with chronic pain and fatigue who just need to get their Vit D or B12 levels raised. - Jarred Younger

    • @davidepattibiomed89
      @davidepattibiomed89 11 หลายเดือนก่อน +3

      @@youngerlab yes, especially considering these come with no negative effects if you avoid over supplementation, which is hard to do in the first place, and you can always test your status. Low Vit D is surely an issue in autoimmunity in general. I have yet to meet a person who did not present with low vit D at diagnosis of autoimmunity, which includes myself.

  • @kimberlyostertag9840
    @kimberlyostertag9840 11 หลายเดือนก่อน +7

    Thank you

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +1

      Thanks! - Jarred Younger

  • @DriveByDoGooders
    @DriveByDoGooders 7 หลายเดือนก่อน +5

    You are a blessing. The real deal. Not bought and sold like most....Super super appreciate you!

  • @BirtheFinstadBruvik
    @BirtheFinstadBruvik 11 หลายเดือนก่อน +3

    Thank you so much for your work and information! I would also add the affordable at-home dry blood spot omega6:3 ratio-test, where the AA/EPA-ratio shows a lot of the chronic inflammation in the body the last 4 months. The Norwegian laboratory VITAS has analyzed almost 1 300 000 test from all over the world now.

  • @KidCity1985
    @KidCity1985 5 หลายเดือนก่อน +4

    How did utube not recommend this channel to when it first started?😊

  • @bcwbarb
    @bcwbarb 8 หลายเดือนก่อน +9

    I was really excited to find your TH-cam channel. I was bitten by a spider(s) in Mexico, exposed to EB through my brother, and 3:22 contracted campylobacter, all in a relatively short period. Over the years since I have been diagnosed with psoriasis, psoriatic arthritis and cancer. I received treatment at UAB that included chemo, radiation and surgery. If my chronic fatigue wasn't bad enough before, it is near overwhelming now. I just saw a video by a medical doctor who also practices functional or naturopathic medicine. He had interesting info on glutathione. I did acquire a TENS/EMS unit with the intent to try vagus nerve stimulation but I haven't mastered exactly how to do it yet. Thanks for your work in this area. It's liberating and validating to hear from someone who is doing more than questioning a patient's sanity

    • @bcwbarb
      @bcwbarb 8 หลายเดือนก่อน +1

      I forgot to add the fibro diagnosed by a rheumatologist. It was the initial diagnosis in this journey. And I had reactive arthritis after the campylobacter infection.

    • @Fomites
      @Fomites 8 หลายเดือนก่อน +2

      ​@@bcwbarbThanks for your story and sorry to learn you have these maladies!

    • @Tinyteacher1111
      @Tinyteacher1111 7 หลายเดือนก่อน +3

      I had a similar experience, but mine was a live Babesia Mycroti Lyme infection which is exactly like malaria. I also have about 7 other Lyme+ infections and resurfaced viruses.
      I feel like I’m dying, but I’m trying to live!

    • @brendabrenner2891
      @brendabrenner2891 6 หลายเดือนก่อน

      ​@@Tinyteacher1111hear u w my ❤️.. am. Long COVID,, past mold exposure, long Lyme(PCP doesn't believe in that), , + now suspect I have fibro.. de dr Paul Anderson, Seattle, on line daily w chrnoc disease info❤️❤️❤️

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +2

      Good luck to both of you on your healing journeys. Have either of you tried LDN? It has helped me a great deal. Not covered by insurance as it is off-label use and I get it through a naturopathic doctor via a compounding pharmacy. But, worth it if you can get it and afford it.

  • @clairenaylor8346
    @clairenaylor8346 11 หลายเดือนก่อน +4

    I love your accessible / understandable approach to your info videos 💙🙏🏼💙

  • @lee-kazz
    @lee-kazz 11 หลายเดือนก่อน +4

    Wonderful info 🎉 thank you 🎉 very helpful 🎉

  • @lisamcmahon1462
    @lisamcmahon1462 8 หลายเดือนก่อน +6

    4blood tests:
    HOMA-IR, HBAIC, AA/EPA Ratio, TGL/HDL ratio.

  • @gradosa8272
    @gradosa8272 7 หลายเดือนก่อน +8

    😭I’m telling my doctors that internal shingles are causing my problems. Yet they refuse to even consider that. After labs results return ok. They shrug their shoulders and say I don’t have anything for you. 😭😭😭The pain is real, debilitating and disabling. can’t wait to retire and move to a place that I can slowly regain my health.

    • @Tinyteacher1111
      @Tinyteacher1111 7 หลายเดือนก่อน +3

      I have a naturopath that said I had resurfaced shingles and other viruses because of Lyme disease. I had no idea that I had this!

  • @DanielleRadicanin
    @DanielleRadicanin 11 หลายเดือนก่อน +4

    My CRP has always been normal but ESR remains elevated. ED docs call the ESR too non-specific yet I have a myriad of autoimmune issues.

  • @Dobrusska
    @Dobrusska 10 หลายเดือนก่อน +8

    I see CPR and ESR normal in most Lyme patients. Any comments?

  • @Fomites
    @Fomites 8 หลายเดือนก่อน +3

    Very informative video. Thank you! 👍I have had polymyalgia rheumatica for about six years with multiple treatments with prednisolone 15 mg weaning to zero with reoccurrences. Lately rheumatologist included leflunomide and it seems to be working which enables cessation of prednisolone. Just for readers' information, my CRP doesn't really indicate the degree of inflammation but the ESR does when we run them in parallel. As well, in the last three or four years I have developed what I suspect is CFS/ME with profound fatigue (but not sleepiness). I will be following your work to help elucidate my malady because this condition being new is hard to diagnose even for experienced generalists. Thanks for your great information!

  • @sweetiepienumber1
    @sweetiepienumber1 5 หลายเดือนก่อน +4

    Keep the faith. Thank you!

  • @EDD519
    @EDD519 2 หลายเดือนก่อน +3

    this test ,inflammation = chronic pain , so why can`t patients get good pain meds ?

  • @mayurgadhave
    @mayurgadhave 24 วันที่ผ่านมา +1

    BEST 2
    1. HSCRP best to be < 1
    2. ESR - below 20
    GOOD TO HAVE
    3. Syrum Ambloyd A (SAA)
    4. Plasma Viscosity (PV)
    5. Interleukin 6 (IL-6)
    6. Tumor Necrosis Factor Alpha (TNF-a)
    7. Ferretin
    8. Fibrinogen
    HONORABLE MENTIONS
    HOMA IR index
    insulin
    C-peptide levels

  • @kathleentaylor8840
    @kathleentaylor8840 7 หลายเดือนก่อน +1

    I’m here after your video 023, which you can tell, by my comment there, was definitely the wrong room for me. I could listen to this video 006 several times for information, however, so now I am intrigued by your range.

  • @marcrichmond3848
    @marcrichmond3848 10 หลายเดือนก่อน +1

    Great videos. Thank you sir. Are you able tp touch on the symptoms too im any of your vidoes please ?

  • @areaman7725
    @areaman7725 11 หลายเดือนก่อน +5

    Dr. Younger - thank you for this information. In your studies, have you observed that people who have ME/CFS have high markers on either/both the hs-CRP and the ESR blood tests?

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +8

      Yes, both -- but I see the most consistent abnormal elevations in CRP. We will probably put out a CRP and ME/CFS paper later this year. I haven't run the calculations, but it is looking like average CRP is around 0.5mg/L for healthy individuals, and around 6.0mg/L for ME/CFS. I don't know if all the labs are finding the same thing, but the difference is very clear in the people we test. - Jarred Younger

  • @banzobeans
    @banzobeans 11 หลายเดือนก่อน +1

    Great topic!

  • @lj9089
    @lj9089 11 หลายเดือนก่อน +1

    So interesting! Thank you!

  • @JMSsssssss
    @JMSsssssss 8 หลายเดือนก่อน +6

    So what do we do if any of those labs are elevated? My hs-crp was 1.6 when last checked. STRONG family history of alzheimer's disease, my father died with it yesterday morning and i keep having to tell my uncle because he keeps forgetting. How do I mitigate inflammation?

  • @deebrooks9488
    @deebrooks9488 10 หลายเดือนก่อน +3

    Hi, what could it mean if your CRP is 1 but you have a high WBC?

  • @eclecticcyclist
    @eclecticcyclist 9 หลายเดือนก่อน +2

    Thank you. In my experience inflammation from foods as the most common cause of RLS and at least one of these tests should be part of a regular health check as it could be the key to stopping many chronic diseases fefore they do any permanent damage.

    • @royrogers495
      @royrogers495 9 หลายเดือนก่อน

      Are you saying inflammation from foods is a different test? If so, what is the best test for food inflammation?

    • @eclecticcyclist
      @eclecticcyclist 9 หลายเดือนก่อน +1

      @@royrogers495 Where did you get that idea? I'm just saying that food is the most common cause of inflammation, especialy given the standard American diet, high in processed foods.

    • @brendabrenner2891
      @brendabrenner2891 6 หลายเดือนก่อน

      ​@@royrogers495.. im. Long covid+ developed food sensitivities.. I avoid hi histamine foods.. use lod fodmap, trying to heal the gut.

  • @OverkiLL-347
    @OverkiLL-347 11 หลายเดือนก่อน +4

    Thank you for your work Dr. Younger! 💚
    If you have inflammation in the spinal cord or brain, as observed in autopsies of seriously ill ME/CFS patients, would you also see this inflammation using normal markers such as CRP or would you have to look at the protein in the spinal fluid, for example?
    And would it also be possible to see inflammation in the spinal cord tissue through blood tests or would you have to get tissue samples?

    • @ninner196
      @ninner196 11 หลายเดือนก่อน

      Good question because for years my csf(cerebral spinal fluid) was tested and it was when my PSA became severe and it was showing there too. Headaches are serious and I think that most of the time they are not associated with an inflammatory disease when I personally have seen evidence showing that it is affected and I am also a patient, my comment was earlier and I am completely disabled.

  • @DanielleRadicanin
    @DanielleRadicanin 7 หลายเดือนก่อน +3

    Each time I attend the ER, they order a CRO but recently refuse to take the ESR which they consider non-spevific. It is always elevated unlike the CRP which is consistently normal.

  • @sparrow646
    @sparrow646 11 หลายเดือนก่อน +1

    Thank you for your work!

  • @shesh4896
    @shesh4896 7 หลายเดือนก่อน +3

    I have had hs crp done for years and that test alone costs me usually over $100. Insurance doesn’t cover it.

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +1

      Wow, that's a lot of $. Perhaps you can try a different lab as the costs can vary widely. Near me, Ulta Labs has a regular charge of $50 and a current sale price of $33.95. Plus they sometimes have sales for bundled testing.

  • @michellewhite5752
    @michellewhite5752 9 หลายเดือนก่อน +1

    My hsCRP is above 10. Keep me in mind. Current UAB patient.

  • @brakeme1
    @brakeme1 7 หลายเดือนก่อน +5

    D-Dimer test for inflammation?

  • @goldilockz6517
    @goldilockz6517 11 หลายเดือนก่อน +6

    Can you cover ferritin and how it is an acute phase reactant that increases during inflammation? I strongly suspect depleted ferritin levels to be a driving factor in my chronic fatigue; however I can’t get an accurate result bc my results are elevated due to inflammation. Women are very prone to low ferritin from pregnancy childbirth and menstruation. Thank you!

    • @goldilockz6517
      @goldilockz6517 11 หลายเดือนก่อน +4

      I wanted to add that the current reference range for “normal” ferritin is very wide and doctors aren’t helpful. Low ferritin can cause many unpleasant symptoms

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +14

      That is a great point about ferritin that I should have made in the video. Thanks for bringing it up. In some of the tests I mentioned, lower is always better. But ferritin and fibrinogen are exceptions where too low can be bad as well because they are involved in processes besides inflammation. Ferritin is critical for iron utilization and low ferritin is a problem for many people. As you noted, in individuals with significant inflammation, ferritin tests stop being useful screens for anemia. And there are some individuals who have inflammation-induced anemia. The related tests like transferrin and direct assessment of iron can help, but I do not think there is a clear marker of inflammatory anemia. The diagnoses need to be pieced together from many sources of info. - Jarred Younger

  • @gforgeorge7
    @gforgeorge7 11 หลายเดือนก่อน +2

    Thank You Dr. Younger. So very appreciated. I'm sharing this to my local support groups to spread the valuable information.

  • @AndreaSteinkuller
    @AndreaSteinkuller 6 หลายเดือนก่อน +3

    You're very good at explaining science to lay people. Thank you.

  • @HeatherKirklandHowe
    @HeatherKirklandHowe 11 หลายเดือนก่อน +1

    Thank you!!! 🙏

  • @minghaogong2343
    @minghaogong2343 11 หลายเดือนก่อน +2

    Dear Dr. Younger, wonderful talk! could you help elaborate how EDR predicts the response rate of LDN?

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +9

      I wish I could attach a pic. But in my fibromyalgia studies, those with ESRs around 15mm/hr have a 20% reduction of pain with LDN, ESRs around 30mm/hr have pain reduction of about 30% on LDN, and ESRs closer to 60mm/hr have a 50% reduction of pain with LDN. There are plenty of exceptions, but those are the general means. And I have run these analyses only in fibromyalgia participants. - Jarred Younger

    • @minghaogong2343
      @minghaogong2343 11 หลายเดือนก่อน

      @@youngerlab Very cooool

  • @vickyfinlayson
    @vickyfinlayson 11 หลายเดือนก่อน +1

    Thank you 😊

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +1

      I'm glad you could watch it! - Jarred Younger

  • @KittenCasserole
    @KittenCasserole 11 หลายเดือนก่อน +5

    Thanks for the information, that’s really helpful. I was wondering about what you said about ESR, that a high number seems to predict that someone might not react well to LDN? Am I understanding that correctly? Does it reason to say that if someone did have a high ESR, and found ways to reduce it to a normal or low number, would they be more likely to respond positively to LDN?

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +6

      Hello! I may have phrased that statement awkwardly. I was trying to say that individuals with high ESR are more likely to respond well to LDN. It seems that LDN works particularly well in people who have evidence of sustained inflammation. - Jarred Younger

    • @KittenCasserole
      @KittenCasserole 11 หลายเดือนก่อน +2

      @@youngerlab Thank you for the clarification, that is really interesting

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +1

      Great question! Thank you for asking as I was wondering this myself. I currently take LDN. Makes sense as at one point my ESR was pretty high. 👍

  • @EzioAuditoreDeFirenze23
    @EzioAuditoreDeFirenze23 2 หลายเดือนก่อน +1

    what does it mean if you have constantly have crp around 4-5 but ESR is low (4)?

  • @Akar_97
    @Akar_97 8 หลายเดือนก่อน +5

    what type of blood test need to inflamation i feel something very weird happen to my body like my heart beat like very weak and super fast like i almost die sometimes even i workout everyday i visit heart doctor take echocardiogram there is no problem i dont know what to do

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +2

      This could be something to do with the vagus nerve. I have experienced this and it can be quite scary. I have had episodes where my heart felt like it had reversed itself (don't know how to explain it....felt like it was doing somersaults) . I listened with a stethoscope and my heart even missed beats for several seconds at a time. Freaking scary. At a later date I had severe chest pain and went to ER immediately and had an EKG and it showed normal sinus rhythm. 😅
      Both times I was just sitting quietly at home reading. But I apparently have a problem with my vagus nerve. Among other things, I found inositol and glycine helpful. My naturopathic doctor told me to try them because I have autonomic dysfunction and sometimes my response to minor stimuli is grossly exaggerated. For example, taking my levothyroxine might feel like I'm taking a giant horse pill and it's tearing up my throat yet it's a teeny tiny pill. Or, turning my head can trigger acute projectile vomiting sometimes with complete loss of bladder control (I'm like ...do I throw up in the toilet and pee on the floor or pee in the toilet and throw up on the floor...??😢). I've been using those two together in powder form and they can be mixed into any beverage. Wow! They really help. And it's powder so I don't have the issues with the pills. I also sometimes lose my voice or my throat spasms. I could go on...everything that the vagus nerve is connected to, basically.

  • @tracioconnor9276
    @tracioconnor9276 7 หลายเดือนก่อน +3

    I am wondering why my son would have an 11.2 for his CRP, but only a six for his ESR. I would have expected the ESR to be high, as well. He has been having some trouble with his liver, and his ALT was also high. I am guessing that the high CRP is because of his liver issues and being overweight. Still, surprised that the ESR was not higher.

    • @Tinyteacher1111
      @Tinyteacher1111 7 หลายเดือนก่อน

      How did you find this out?

  • @williamhuard3860
    @williamhuard3860 9 หลายเดือนก่อน +4

    I have long COVID since 2021 and I tried to travel to florida beginning of April and ended up in the ER with extensive clotting
    My c reactive protein was 21 which was high
    I’m having a reaction to ivermectin and LDN over the first few weeks
    So discouraged!

    • @arubaga
      @arubaga 6 หลายเดือนก่อน +1

      3 additional things: Berberine, pepcid, Lauriciden

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +3

      I think I had an initial problem with LDN, too. I had to stop it for a while. When I resumed I started at 1.5 mg and took that for a good while before going up to 3mg. Now I have no problems with it.

    • @SH-jg5zq
      @SH-jg5zq 2 หลายเดือนก่อน

      I had high d dimer since getting Covid in 2021. CRP goes up and down. Ferritin ok. Fibrinogen ok. TNF alpha high.

  • @robertmoore2374
    @robertmoore2374 3 หลายเดือนก่อน +1

    Will these test detect past inflammation that your not feeling now?

  • @alexsokoloff4188
    @alexsokoloff4188 9 หลายเดือนก่อน +1

    Thank you so much for such informative video!
    I'm just curious what markers could be a reflection of inflammation caused by chronic viral/bacterial activity (which many of CFS patients have).
    For instance I have extreme fatigue and chronic EBV/CMV activity but hs-CRP, ESR, IL-6, ferritin and TNF alpha are in normal ranges.

  • @guidodenbroeder935
    @guidodenbroeder935 หลายเดือนก่อน

    In ME, ESR is known to fluctuate a lot, from zero to very high.

  • @kimmcdaniel8933
    @kimmcdaniel8933 7 หลายเดือนก่อน +6

    Would you please explain brain fog? Is brain fog inflammation of the brain?

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน +3

      “Brain fog” is a term used to describe a state of mental confusion or lack of mental clarity. It is not a medical condition itself but a symptom of other conditions. People experiencing brain fog may have trouble with memory, concentration, and processing information.
      Causes of Brain Fog:
      1. Stress and Anxiety: Chronic stress and anxiety can impair cognitive function.
      2. Lack of Sleep: Poor sleep quality or insufficient sleep can lead to cognitive issues.
      3. Nutritional Deficiencies: Deficiencies in essential vitamins and minerals, such as vitamin B12, can affect brain function.
      4. Medications: Some medications have side effects that include cognitive impairment.
      5. Medical Conditions: Conditions like hypothyroidism, fibromyalgia, chronic fatigue syndrome, and autoimmune diseases can cause brain fog.
      6. Hormonal Changes: Hormonal imbalances, such as those occurring during menopause or pregnancy, can affect cognitive clarity.
      7. Mental Health Disorders: Depression and other mental health disorders can contribute to feelings of brain fog.
      8. Infections: Some infections, including COVID-19, have been associated with cognitive symptoms like brain fog.
      9. Dehydration: Not drinking enough water can affect cognitive function.
      Identifying and addressing the underlying cause is essential for managing and reducing brain fog.

    • @The_New_Abnormal_World_Order
      @The_New_Abnormal_World_Order 6 หลายเดือนก่อน +1

      One major cause is dysregulated blood sugar. Apparently another major cause is inflammation of the brain.

    • @mattpotter8725
      @mattpotter8725 5 หลายเดือนก่อน

      @@Sam-ci8bp I'm sorry but I strongly disagree, brain fog is a symptom caused by a medical issue. Whilst what you say might be technically true, it's potentially caused by all or any of the things you list what you're saying to me sounds a lot like how people with debilitating conditions are treated until quite recently when ME/CFS was dismissed as being all in the head. Brain fog is one the medical symptoms that can suggest you may have long COVID or ME/CFS. I find this comment extremely unhelpful.

    • @mattpotter8725
      @mattpotter8725 5 หลายเดือนก่อน

      @@Sam-ci8bp I didn't say I know there's a cure or that I disagree that it isn't caused by certain things you mentioned in your comment just that what you said didn't disqualify it from being a medical condition. I also think we should stop thinking in black and white ways about something that will obviously be very complex. Would you say a headache isn't a medical condition/symptom? There are also many causes as to why you might have a headache but that doesn't mean it's not a medical condition, and the treatment of it would depend on the cause. So having brain fog, a medical symptom, is a necessary piece of the jigsaw in diagnosing the treatment of a patient, or do you disagree with this?

  • @michellewhite5752
    @michellewhite5752 9 หลายเดือนก่อน +1

    Hi I’d love to be a guinea pig! Chronic inflammation for decades. I’m a patient at UAB.

  • @joycewedel9084
    @joycewedel9084 7 หลายเดือนก่อน +6

    Ty. I have chronic pain & would love to be in a research study.

  • @tinkerbellbetty
    @tinkerbellbetty 8 หลายเดือนก่อน +2

    Fibromyalgia. My child esinophilic esophagus. So fed up

  • @HarpreetKaur-ti2xp
    @HarpreetKaur-ti2xp 5 หลายเดือนก่อน +2

    Sir we appreciate the effort you put ❤
    Sir when CRP is high in case of a knee injury is it normal thing ?
    I had CRP 22.2 and was about to set to get an injection in knee and was given
    My health deteriorated another doctor said I should not have been injected with CRP. 22.2

    • @youngerlab
      @youngerlab  3 หลายเดือนก่อน

      Yes, acute injury can transiently raise CRP levels. It will likely stay increased as long as the immune system is repairing the damage. The temporary increase is not a cause of concern. - Jarred Younger

  • @guidodenbroeder935
    @guidodenbroeder935 หลายเดือนก่อน

    What about an IFN-γ test?

  • @banzobeans
    @banzobeans 11 หลายเดือนก่อน

    What say you about the blood serum marker Rantes aka CCL5?
    My Rantes value was strongly elevanted before a NICO jaw excavation surgery.
    Dropped to normal after surgery.
    Now elevated again 2 years after the NICO surgery.

  • @georgiachristenson5257
    @georgiachristenson5257 11 หลายเดือนก่อน +1

    Thank you Dr. Younger.

  • @bradsalz4084
    @bradsalz4084 11 หลายเดือนก่อน +5

    How do you test for auto-antibodies in the CSF? My neurologist suspects that I have an auto-immune condition triggered by by a covid infection resulting in lingering symptoms. But this requires a spinal puncture to investigate. Is there any blood test that could be done first (or instead) that could be used to rule this out before going to the more invasive procedure?

    • @alias701
      @alias701 10 หลายเดือนก่อน +3

      GPCR antibodies Test. Available in Germany. Send it there

    • @ridhima_vlogs_
      @ridhima_vlogs_ 10 หลายเดือนก่อน +1

      Ok

    • @bradsalz4084
      @bradsalz4084 10 หลายเดือนก่อน +1

      @@alias701 How does this differ from the standard ANA (anti-nuclear antibody) blood test? My neurologist says this blood test tells you nothing about what's happening in the CSF, i.e. the blood test could come back negative but it doersn't mean that autoantibodies don't exist in the CSF.

    • @Sam-ci8bp
      @Sam-ci8bp 6 หลายเดือนก่อน

      @@bradsalz4084this test is for autoantibodies against a type of cell surface receptor involved in many physiological processes.

  • @Mau365PP
    @Mau365PP 11 หลายเดือนก่อน +1

    During my 2nd acute infection my CRP was up to 35 😢

    • @youngerlab
      @youngerlab  11 หลายเดือนก่อน +1

      You probably felt quite poorly then! 35mg/L is not unusual for a flu or similar viral infection. Bacterial infections can take it well over 100mg/L. When I see over 20mg/L in my lab, it is usually an acute infection of some sort. In those cases, I just give them a couple of weeks and we re-test. - Jarred Younger

  • @myrtarivera4244
    @myrtarivera4244 8 หลายเดือนก่อน +1

    I've recently discovered through a series of blood tests performed in the hospital that I had Sepsis. The labs taken show markers and that's how the 6 kidney surgeons decided to perform an immediate ureteroscopy and lithotripsy. I lived to share this story with you, but still have the side effects. What do you suggest I do now? Do I see a hematologist?

    • @Tinyteacher1111
      @Tinyteacher1111 7 หลายเดือนก่อน +1

      Is this sepsis, because no one tells me anything and I have a new doctor after mine retired unexpectedly.
      I contracted pseudonymous aeriginosa during a breast implant removal operation (where I actually stopped breathing and had to be revived), and no one would believe I had anything wrong with my excruciating chest pain until my incision festered 8 weeks later. I was put in cipro. I absolutely feel it did something to me because I developed leg pain that I had as a child after that infection.
      I also have other health problems from the implants, autoimmune diseases, infections, mold toxicity, Lyme disease, brain fog and now I’m in freeze response from CPTSD.

  • @swapnilamundra
    @swapnilamundra 5 หลายเดือนก่อน

    Can someone recommend a good doctor in Manhattan

  • @andrearositas4887
    @andrearositas4887 11 หลายเดือนก่อน +1

    I have post Covid and have IL-6 and TNF very high. Any insights why?

    • @abstuli
      @abstuli 10 หลายเดือนก่อน +2

      Probably Mast cell activation syndrome (MCAS).
      IL-6 and TNF are two of over 1050 different types of mediators that Mast cells can produce and release, where a large part of them are inflammatory.
      There are also other immune cells that can release IL-6 and TNF.
      From BBC. Long Covid triggered our MCAS, but doctors didn't believe us
      From National Institutes of Health (NIH).
      Mast cell activation symptoms are prevalent in Long-COVID
      Mast cell activation syndrome and the link with long COVID
      Mast cell activation is associated with post‐acute COVID‐19 syndrome
      Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome
      Immunological dysfunction and mast cell activation syndrome in long COVID

  • @adamscaife6931
    @adamscaife6931 5 หลายเดือนก่อน +2

    I've had normal results for CRP, is that the same as hs-CRP?

    • @N17sd
      @N17sd 5 หลายเดือนก่อน +2

      Yes the same

    • @Dusankoa
      @Dusankoa 5 หลายเดือนก่อน +2

      It is not the same

    • @GrammaSheila5
      @GrammaSheila5 4 หลายเดือนก่อน +2

      @@Dusankoa I believe HS is high sensitivity

  • @vilrey1000
    @vilrey1000 5 หลายเดือนก่อน +2

    I wish the last 6 test was explained

    • @tonymaurice4157
      @tonymaurice4157 4 หลายเดือนก่อน

      Just get on a plant-based diet

  • @The_New_Abnormal_World_Order
    @The_New_Abnormal_World_Order 6 หลายเดือนก่อน +1

    Does anyone know the cheapest place to test C reactive protein in the UK? or if it's easy to get the test on NHS?

    • @Dusankoa
      @Dusankoa 5 หลายเดือนก่อน +1

      Easy to get on nhs. Just ask your gp

  • @Tinyteacher1111
    @Tinyteacher1111 7 หลายเดือนก่อน +9

    PLEASE tell me where you are located? My son will die soon if I we can’t find the root cause of his pain, depression, anxiety, and autoimmune encephalitis after Meningitis at age 7. He’s 38, a recluse, living with his father, and their house was full of mold (remediated, but I think it’s still toxic.), has tried to take his life several times. His headaches are making him suicidal.

    • @awaken69
      @awaken69 6 หลายเดือนก่อน

      he needs to move out of the house asap. implement a strict ketogenic auto-immune paleo diet (or a lions diet if he wants to keep it as simple as possible). he MUST be 100% gluten and dairy free. add 2g of EPA/DHA per day, 1g of Krill Oil, curcumin, some PEA and Holy Basil. 3x1g Vit C, and a high quality B vitamin complex per day. Add Luteolin, Apigenin, Eutropoflavin as needed. The latter has a strong anti-depressant effect (similar to psilocybin). Add ProdromeGlia (plasmalogens) if possible (quite expensive, but worth it!)

    • @Queenofthebackroads
      @Queenofthebackroads 6 หลายเดือนก่อน +1

      Thank you. Where did you obtain your knowledge and where do you purchase the substances you mention?​@@awaken69

    • @The_New_Abnormal_World_Order
      @The_New_Abnormal_World_Order 6 หลายเดือนก่อน +1

      Dr Myhill in the UK would probably have a lot of advice on her website that might help you.

    • @Tinyteacher1111
      @Tinyteacher1111 5 หลายเดือนก่อน

      @@The_New_Abnormal_World_Order Thank you!!!!🙏

  • @banzobeans
    @banzobeans 11 หลายเดือนก่อน +3

    What say you about the hypothesis of impaired lymphatic drainage & interstitial inflammatory stasis?
    I find it quite compelling as I've felt myself surprising (transitory) positive effects on my mood and mind abd overall energy right after lymphatic massage of head and shoulders.

  • @marscience7819
    @marscience7819 7 หลายเดือนก่อน +4

    I'm not sure what labs Dr. Younger are referring to, but none of these are listed at Quest "serum amyloid a", "plasma viscosity", "fibrinogen", "il-6" , "tnf-a"

  • @dolly3016
    @dolly3016 7 หลายเดือนก่อน +4

    My CRP is 30 and my sed rate is 58, just fyi - ya, I'm concerned!

    • @krislinden
      @krislinden 7 หลายเดือนก่อน

      Maybe it’s polymyalgia rheumatica?

  • @ridhima_vlogs_
    @ridhima_vlogs_ 10 หลายเดือนก่อน

    Ok

  • @tinkerbellbetty
    @tinkerbellbetty 8 หลายเดือนก่อน

    Hot breath

  • @tinkerbellbetty
    @tinkerbellbetty 8 หลายเดือนก่อน

    Nhs ask for test your having a laugh

  • @tonymaurice4157
    @tonymaurice4157 4 หลายเดือนก่อน +1

    Plant based diet is best

    • @npcarnivore
      @npcarnivore 3 หลายเดือนก่อน +2

      Nope, unless you mean you eat animals that eat vegetables, then yes!

    • @tonymaurice4157
      @tonymaurice4157 3 หลายเดือนก่อน

      @@npcarnivore we are not lions.

    • @npcarnivore
      @npcarnivore 3 หลายเดือนก่อน +2

      @@tonymaurice4157 how many pounds of soy do you have to eat per day?

    • @tanyawieczorek6603
      @tanyawieczorek6603 หลายเดือนก่อน +2

      ​@@tonymaurice4157 we're not cows, either.
      All those arrowheads and spear points found in ancient caves weren't used as letter openers 😅

    • @nataliegist2014
      @nataliegist2014 7 วันที่ผ่านมา

      ⁠@@tonymaurice4157no we aren’t, but I’ve been on the carnivore diet for a couple of years, and it has healed 9 issues from the neck up. I am also off 8 different precipitation medication.