Thank you for your reply, praying for a miracle for all who suffer from any sort of chronic pain and inflammation. Thank you so much for continuing to find answers, to help those desperately seeking help.
Great video! Thanks Jared, you have a great way of explaining complex issues in simple ways people can understand. I am a CFS sufferer and have been looking into neuro-inflammation for some time, and its amazing how rare it is for researchers to simply address issues such as state the reasons why it is difficult to study...
Thank you so much from the bottom of my heart Dr Younger for all the efforts and amazing work you put into the field of ME/CFS and FM. It gives us a lot of hope. In Denmark, where I am from, most doctors still insist that ME is a somatoform disorder and not a real fysiological illness - even after we have provided them numerous scientific articles proving the opposite. I don't know what it will take for them to realize they are wrong. But again, you give us a lot of hope. I also truly hope that you and your team will make major discoveries leading to a biomarker and ultimately a curing treatment. Best regards, Anna Maria Lassen, ME-patient for 9 years. Got ill immediately after having an influenza vaccination.
I had trouble staying on keto for weight loss because I would forget how fat I was and just want to eat snacks. But after I watched Dr. Younger's explanation that my chronic fatigue and dizziness were caused by sugars & carbs swelling my brain, I've had no problem staying on keto! Thank you, sir!
@@nomotmo The explanation for chronic fatigue being linked to brain inflammation? That is contained in a speech or interview by Dr. Younger on youtube. I don't remember which one. But I do recall he studied the brains of people with chronic fatigue syndrome using an MRI machine and found that reduced bloodflow at crucial places in the brain caused the brain to overheat in these areas. The symptoms caused by this overheating are similar to having a fever when you're very sick; you feel tired and want to lay down for awhile until you feel better. But since the inflammation continues indefinitely, you feel tired every day. The solution seems to be fasting and reducing inflammation agents from your diet.
I'm a hemorrhagic stroke survivor who had a craniotomy and have been searching for information to understand my post stroke fatigue. thank you for the information
Top 10 current treatments both natural & pharmaceutical would be useful. Thank you for these videos, they are hope-inducing. Please some more practicalities though.
Isn't it true that neuroinflammaion can affect nerves in parts of the body other than the brain giving rise to things like RLS or some forms of Sciatica?
Just discovered tour channel today; amazing info you’re giving everyone. I watched your COVID-19 Psychology video and It was very reassuring. Thanks for all you
In my particular case, 29 years now, I have abnormal movements.They are being labled paroxysmal dyskinesia. They result in convulsions and/or myclonus and/or dystonia. In the ER, the ammonia capsules, give me a startle reflex, and just as being greatly startled can cause an episode, a great startle like that caused my ammonia being shoved up your nose, causes one to jolt my body out of jerking, or dystonia, usually. If I can get a body part near the one the is "acting up," I can work out the problem without other intervention.I truly believe it has been labeled a pseudoseizure because of that. So my whole problem is not taken seriously at UAB. That is my honest opinion. I hope I am wrong.
Is there a working hypothesis on how neuroinflammation and exertion intolerance are connected? I ask as this is by far the most defining and debilitating aspect for myself and many others. The more I do, the worse I feel, has absolutely held true after all these years along with the delayed reaction to it. Thanks so much for taking on this project!
+85bigsky Absolutely will talk about exertion intolerance soon. A few clues coming out of recent research by other groups, some suggesting either exaggerated inflammatory response to exertion, or a suppressed anti-inflammatory response to exertion. There are other models as well. We are tracking immune parameters over time and will build in an optional exertion test near the end of the study to see how it affects levels of various immune components.
i had an mri after neurologist notice possible signs of m.s. the mri confirm inflammation in my brain. then i had a lumbar puncture to confirm if i had m.s. it showed that i did NOT have inflammation in my spinal fluid. so i have to go back to neurologist in may for checkup mri. i had to literally beg to get a referral to see neurologist. if i didnt, i would have never known about inflammation in my brain.
believe I have neuroinflammation and have had it for awhile. It comes and goes in waves etc and this last time I developed aphasia. It has been going on for three weeks now. Mris are fine. But I have suffered many bouts of It for awhile. I did have viral encephalitis as a teen and a couple of head Injuries when I was younger No one can put this puzzle together.
New subscriber. Diagnosed w/CFS in the early 90's, seemed to remiss until subsequently diagnosed w/FMS in 2000. Seems I have been on every drug there is at some point; going off Opioids now at my request. After that, hope to try LDN. Doc says more research is needed but is willing to try it. Thanks to you and your colleagues for taking on your hypothesis about CFS and FMS. Having been diagnosed with each, at separate times, I feel they are closely related or part of the same issue...the only difference I can say is that symptomatically, with CFS I had frequent fevers, sore throat and hoarseness - not experienced since FMS dx. Question: Any thoughts on Gabatril for FMS? Joni M.
+Joni Minor The link between FM and CFS is still controversial. In our lab, we are working under a default hypothesis that the diseases are more similar than they are different, but of course we will change our mind if the research evidence says otherwise. This topic will certainly be the focus of a future video. Gabatril basically slows down neural firing. When it slows down the neurons that transmit pain, it decreases pain. The fewer times the pain neurons fire, the less pain you feel. The downside is that it doesn't target the pain neurons specifically, so you get slowing of other systems as well. The drug can help some people, but we think it is reducing the symptoms rather than correcting the core problem.
Hi, my mom is in coma right now, the neurologist says there is already a brain swelling, is it reversible? She has eye movements but I don't think that she recognizes us, also her limbs are only reacting to pain. Will she be able to wake up?
Great article, well this apply to autoimmune diseases as well, which are said to be caused by inflammation? I want to thank you so much for your research and all you are doing for those suffering😃
+Yoli Torres Absolutely. Autoimmune disorders involve inflammation - the main difference being that the trigger of the inflammation is (supposedly) our own cells instead of foreign elements that have entered the body. This general theme would apply to people with rheumatoid arthritis and other autoimmune conditions, especially if they feel profoundly fatigued, increased depressed feelings, and have alterations in thinking, memory, and concentration.
Omg dear doc I have had to listen to your video twice. I have cfs, and have explained to my doctor that my brain hurts, I can not retain information and she think I'm talking rubbish. My fatigue is getting worse. It hurts my arms to put makeup on, trying to be normal. Please test on me, or is there someone you can help here in the uk, London. Thank you for your work gob bless you.
I wish if I had studied medicine that I could have been a neurologist to work on these types of fascinating research , but why I got this idea at the age of 35 ? !! Couldn't it be a bit sooner ?
My dad is 74,he is getting over covid.His fever was 103.6.He is having memory issues.He spent a mont in the hospital.12-28-2020 to 1-28-2021.He is having problems keeping and holding a conversation.I want to bring him to see you,would that be possible?
Thank you for your reply, praying for a miracle for all who suffer from any sort of chronic pain and inflammation. Thank you so much for continuing to find answers, to help those desperately seeking help.
Great video! Thanks Jared, you have a great way of explaining complex issues in simple ways people can understand. I am a CFS sufferer and have been looking into neuro-inflammation for some time, and its amazing how rare it is for researchers to simply address issues such as state the reasons why it is difficult to study...
+Stephen Wright Thanks! We'll keep it up!
I realize it's kind of off topic but do anyone know a good place to stream new tv shows online ?
@Korbin Brayan i would suggest Flixzone. You can find it by googling :)
@Yehuda Nehemiah Yup, I have been using Flixzone for since april myself =)
@Yehuda Nehemiah Thanks, I went there and it seems like they got a lot of movies there =) I appreciate it!!
Thank you so much from the bottom of my heart Dr Younger for all the efforts and amazing work you put into the field of ME/CFS and FM. It gives us a lot of hope. In Denmark, where I am from, most doctors still insist that ME is a somatoform disorder and not a real fysiological illness - even after we have provided them numerous scientific articles proving the opposite. I don't know what it will take for them to realize they are wrong. But again, you give us a lot of hope. I also truly hope that you and your team will make major discoveries leading to a biomarker and ultimately a curing treatment.
Best regards,
Anna Maria Lassen, ME-patient for 9 years. Got ill immediately after having an influenza vaccination.
How are you doing now?
Is there an update to these findings in 2022? How does one find a way to test?
I had trouble staying on keto for weight loss because I would forget how fat I was and just want to eat snacks. But after I watched Dr. Younger's explanation that my chronic fatigue and dizziness were caused by sugars & carbs swelling my brain, I've had no problem staying on keto! Thank you, sir!
Where can I find that explanation?
@@nomotmo The explanation for chronic fatigue being linked to brain inflammation? That is contained in a speech or interview by Dr. Younger on youtube. I don't remember which one. But I do recall he studied the brains of people with chronic fatigue syndrome using an MRI machine and found that reduced bloodflow at crucial places in the brain caused the brain to overheat in these areas. The symptoms caused by this overheating are similar to having a fever when you're very sick; you feel tired and want to lay down for awhile until you feel better. But since the inflammation continues indefinitely, you feel tired every day. The solution seems to be fasting and reducing inflammation agents from your diet.
@@widehotep9257 Thank you very much for your reply!
Can you please post more videos, it is really easy to understand the information, thank you!
I'm a hemorrhagic stroke survivor who had a craniotomy and have been searching for information to understand my post stroke fatigue. thank you for the information
You are welcome! -- Jarred Younger
Keto and carnivore helps alot
Please address the solutions
Thank you for this great video. Very clear and informative. Looking forward for new ones..
+Erdem Ergaz I appreciate it!
Top 10 current treatments both natural & pharmaceutical would be useful. Thank you for these videos, they are hope-inducing. Please some more practicalities though.
+Chloe Clearly Absolutely. I promise we will get to those topics.
Isn't it true that neuroinflammaion can affect nerves in parts of the body other than the brain giving rise to things like RLS or some forms of Sciatica?
Just discovered tour channel today; amazing info you’re giving everyone. I watched your COVID-19 Psychology video and It was very reassuring. Thanks for all you
Hi! What's your opinion on CBD (Cannabidiol) oil for neuroinflammation? Does it have a future in research?
In my particular case, 29 years now, I have abnormal movements.They are being labled paroxysmal dyskinesia. They result in convulsions and/or myclonus and/or dystonia. In the ER, the ammonia capsules, give me a startle reflex, and just as being greatly startled can cause an episode, a great startle like that caused my ammonia being shoved up your nose, causes one to jolt my body out of jerking, or dystonia, usually. If I can get a body part near the one the is "acting up," I can work out the problem without other intervention.I truly believe it has been labeled a pseudoseizure because of that. So my whole problem is not taken seriously at UAB. That is my honest opinion. I hope I am wrong.
Is there a working hypothesis on how neuroinflammation and exertion intolerance are connected? I ask as this is by far the most defining and debilitating aspect for myself and many others. The more I do, the worse I feel, has absolutely held true after all these years along with the delayed reaction to it.
Thanks so much for taking on this project!
+85bigsky Absolutely will talk about exertion intolerance soon. A few clues coming out of recent research by other groups, some suggesting either exaggerated inflammatory response to exertion, or a suppressed anti-inflammatory response to exertion. There are other models as well. We are tracking immune parameters over time and will build in an optional exertion test near the end of the study to see how it affects levels of various immune components.
Look into chronic inflammatory response syndrome and Dr Heyman
i had an mri after neurologist notice possible signs of m.s. the mri confirm inflammation in my brain. then i had a lumbar puncture to confirm if i had m.s. it showed that i did NOT have inflammation in my spinal fluid. so i have to go back to neurologist in may for checkup mri. i had to literally beg to get a referral to see neurologist. if i didnt, i would have never known about inflammation in my brain.
believe I have neuroinflammation and have had it for awhile. It comes and goes in waves etc and this last time I developed aphasia. It has been going on for three weeks now. Mris are fine. But I have suffered many bouts of It for awhile. I did have viral encephalitis as a teen and a couple of head Injuries when I was younger No one can put this puzzle together.
good morning, have you tested for PARKINSON`S DISEASE ?
QUESTION: Is excessive phlegm in throat a sign of neurological inflammation? Thanks
does Neuro inflammation keep returning after tbi
New subscriber. Diagnosed w/CFS in the early 90's, seemed to remiss until subsequently diagnosed w/FMS in 2000. Seems I have been on every drug there is at some point; going off Opioids now at my request. After that, hope to try LDN. Doc says more research is needed but is willing to try it. Thanks to you and your colleagues for taking on your hypothesis about CFS and FMS. Having been diagnosed with each, at separate times, I feel they are closely related or part of the same issue...the only difference I can say is that symptomatically, with CFS I had frequent fevers, sore throat and hoarseness - not experienced since FMS dx.
Question: Any thoughts on Gabatril for FMS?
Joni M.
+Joni Minor The link between FM and CFS is still controversial. In our lab, we are working under a default hypothesis that the diseases are more similar than they are different, but of course we will change our mind if the research evidence says otherwise. This topic will certainly be the focus of a future video. Gabatril basically slows down neural firing. When it slows down the neurons that transmit pain, it decreases pain. The fewer times the pain neurons fire, the less pain you feel. The downside is that it doesn't target the pain neurons specifically, so you get slowing of other systems as well. The drug can help some people, but we think it is reducing the symptoms rather than correcting the core problem.
Can i speak to you about a suspected severe acute brain inflammation case? would be a life saver
Hi, my mom is in coma right now, the neurologist says there is already a brain swelling, is it reversible? She has eye movements but I don't think that she recognizes us, also her limbs are only reacting to pain. Will she be able to wake up?
Great!
Great article, well this apply to autoimmune diseases as well, which are said to be caused by inflammation? I want to thank you so much for your research and all you are doing for those suffering😃
+Yoli Torres Absolutely. Autoimmune disorders involve inflammation - the main difference being that the trigger of the inflammation is (supposedly) our own cells instead of foreign elements that have entered the body. This general theme would apply to people with rheumatoid arthritis and other autoimmune conditions, especially if they feel profoundly fatigued, increased depressed feelings, and have alterations in thinking, memory, and concentration.
Omg dear doc I have had to listen to your video twice. I have cfs, and have explained to my doctor that my brain hurts, I can not retain information and she think I'm talking rubbish. My fatigue is getting worse. It hurts my arms to put makeup on, trying to be normal. Please test on me, or is there someone you can help here in the uk, London. Thank you for your work gob bless you.
Try the win Hoff method
I wish if I had studied medicine that I could have been a neurologist to work on these types of fascinating research , but why I got this idea at the age of 35 ? !! Couldn't it be a bit sooner ?
Listen to your inner being you are still young you can still studying and become a doctor I’ve heard of older people living their dream you can’t to
Miss spelling you can live your dream
My dad is 74,he is getting over covid.His fever was 103.6.He is having memory issues.He spent a mont in the hospital.12-28-2020 to 1-28-2021.He is having problems keeping and holding a conversation.I want to bring him to see you,would that be possible?
THE PAIN!!!!!!
help. this is ruining my marriage
Neuroinflammation can be detected with a DUTCH-test