Lupus nephritis - causes, symptoms, diagnosis, treatment, pathology
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- เผยแพร่เมื่อ 13 มิ.ย. 2022
- What is lupus nephritis? Lupus nephritis is inflammation of the nephrons of the kidney that's caused by systemic lupus erythematosus.
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I'm so glad i found this video. I finally understand what actually happened to me 4 years ago
My transcript notes of the video:
00:03
The term lupus refers to systemic lupus erythematosus nephritis refers to the nephron the greek word for kidney and itis means inflammation so lupus nephritis refers to
00:15
inflammation of the kidney that results from having systemic lupus erythematosus lupus is an autoimmune disease in which the immune system attacks various parts of the body including the skin the joints lungs heart central nervous
00:29
system and of course the kidneys in fact about half of all individuals with lupus develop some form of lupus nephritis in lupus what happens is that some cells have their dna so badly damaged that the
00:43
cell undergoes programmed cell death or apoptosis and it dies this produces all these little apoptotic bodies and exposes the insides of the cell including parts of the nucleus like dna
00:57
histones and other proteins to the rest of the body now with lupus the immune system is more likely to think that the cellular parts are foreign or antigens and since they're from the nucleus
01:09
they're referred to as nuclear antigens and immune cells try to attack them not only that though individuals with lupus have less effective clearance essentially meaning they aren't as good at getting rid of these apoptotic bodies
01:23
and so they end up having more nuclear antigens floating around so as a result of all this b cells start producing antibodies against these pieces of nucleus which are called anti-nuclear antibodies
01:36
these anti-nuclear antibodies bind to nuclear antigens forming antigen antibody complexes which drift away in the blood and deposit in various places including the kidneys
01:49
these immune complexes can then initiate an inflammatory reaction which is known as a type 3 hypersensitivity reaction lupus nephritis is classified into various types depending on the exact site of these immune complexes and
02:05
subsequent inflammatory reaction the most common side of deposition is just underneath the capillary wall also known as the endothelium but deposits can also be within the bowman space of the nephron the basement
02:17
membrane or near the mesangio cells the extent of inflammation within the kidney can be focal which involves nephrons in just one area or diffuse involving almost all the nephrons in both kidneys
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this was so helpful, thank you. makes it so much clearer
You're very welcome! 😊
Loved the way you teach❤💯
Thank you, Angel! 😃
Informative video,thank you
Most welcome! 👍🏼
Thanks for sharing
Thanks for watching! 😊
Loved it thank u soooo much♥️♥️
Most welcome, Saira! 🙏🏼
Thank you very much 💜
Welcome! 😊
This is helpful 😊thanks sir
Welcome! 😊
Thank you💖
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Thanks
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Loads of love for Osmosis.. very nice platform for learning
Thank you, Rehankhan! 🥰❤️🙏🏼
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Great video thank you, can this only be found out by a kidney biopsy or is there other ways? I have lupus SLE and have a new urologist (my last one who was great left the hospital I’m at) he has booked surgery to check out my bladder next week… can he check out my kidneys through stretching my bladder under general anaesthetic? Oh pre-op assessment is today 🙏🏾❤️🇬🇧
I have been suffering from Lupus disease for some year without having a solution to it until i done a research on TH-cam i come and cross Dr.Auchi on TH-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️
The bladder is checked with a Cystoscopy procedure.
My mom just got diagnosed with this (on top of sle and sjogren's). Glad there's probably not a huge genetic component 😢
Thanks for the education.
Most welcome 🙏🏼
Very nice
Thank you! 🙏🏼
🤗informative
Thanks! 💕
Can you tell me you edit videos? Because they are very beautiful
What software is used to create this kind of video?
Hi Stelyo! Thanks for asking! Here’s how Osmosis videos are made: www.osmosis.org/blog/2020/11/27/how-osmosis-videos-are-made# 👍🏼
@@osmosis Thank you. I’m gonna try it out as I want to create content like this but for biochemistry and in my local language (Portuguese) because our students can’t really understand English.
I have been suffering from Lupus disease for some year without having a solution to it until i done a research on TH-cam i come and cross Dr.Auchi on TH-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️
Sheesh cool 🔥🔥
Thanks, Mina! 👍🏼
❤❤❤
I have Lupus. It sucks.
I was really happy I got a recommendations of Dr Ewi1 on youtube that cured me of my Lupus diseases. I used his herbal medicine in less than a month I swiftly recovered from this disease
I have been suffering from Lupus disease for some year without having a solution to it until i done a research on TH-cam i come and cross Dr.Auchi on TH-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️
Is there any cure for this disease
No
Why r u so fast ?
Hi! You may adjust the video speed on the menu at the bottom of the video screen to a more comfortable speed. We hope this helps! 🙏🏼
@@osmosis ok sir thanks
It's never lupus "house M.D"
I was really happy I got a recommendations of Dr Ewi1 on youtube that cured me of my Lupus diseases. I used his herbal medicine in less than a month I swiftly recovered from this disease
I have been suffering from Lupus disease for some year without having a solution to it until i done a research on TH-cam i come and cross Dr.Auchi on TH-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️
Keluar agen farmasi dan
That's what happened to Selena Gomez right? she has Lupus and Had to get a Kidney transplant.
yeah
She doesn’t have lupus, she has a lupus like disease. Maybe MCTD?
Yes, she would have almost died if it wasn't for her best friends donating her one of kidneys.
I have been suffering from Lupus disease for some year without having a solution to it until i done a research on TH-cam i come and cross Dr.Auchi on TH-cam channel. That was were i find effective herbal medicine to cure my Lupus disease permanently without having side effect from the herbal product.. i recommend Dr.Auchi herbal medicine for Lupus disease cure...❤️❤️
Guess who is watching 😕😕
Just taken an exam today and verifying my answer....😥😥😥😥🙃🙃🙃🙃and it turned out wrong😕😕😕😕😕😕😕.....
Let's do better at the next one, then! 👍🏼 You may view our entire video library when you signup for a trial account at osmosis.org (we won't charge you once the trial expires) for the topics that you need that aren't available on our channel. 🙏🏼
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