V.A.C. Roundtable #84 Cannabinoid Hyperemesis Syndrome with special guest Dr. Ethan Russo

Today, we’re diving into an important and often misunderstood topic: Cannabinoid Hyperemesis Syndrome (CHS). This condition has sparked significant discussion within the cannabis community and beyond, and we’re here to bring clarity and understanding.
We’re honored to be joined by Dr. Ethan Russo, a world-renowned expert and researcher on CHS. Dr. Russo will guide us through the science, dispel common myths, and help us understand this complex issue.
Whether you’re a healthcare professional, advocate, or curious mind, this discussion is packed with valuable insights you won’t want to miss.
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[@eryckstamper7264]

Very critical information on CHS!!

[@msbluesman]

Awesome info

[@msbluesman]

So happy to learn this! You rock

[@msbluesman]

Love and respect Dr. Russo!

[@msbluesman]

Haldol is a knock out drug correct? Not too much difference from general anesthesia really? Could be a little overkill

[@codipeterson3590]

Haloperidol is a "classical antipsychotic" medication; nothing like anesthesia. But does make people sleepy, which adds to it's ability to tolerate or even break an episode

[@msbluesman]

I suggest this syndrome could possibly be from a defect in the enzyme responsible for degradation of endo and exogenous cannabinoids it’s called fatty acid amide hydrolase or FAAH ! Theoretically an enzymatic dysfunction in FAAH would cause an excess in all cannabinoids that would have prolonged effect and possibly biphasic effect on emesis! I have no proof of this but dysfunction in enzyme systems are common and become the limiting step in an enzyme cascade! 😮

[@codipeterson3590]

FAAH does not breakdown THC.... but it is a component of the ECS... And i would postulate that it is indeed a dysregulation of the ECS but not specifically FAAH (but multi-component)