I’ve been fasting for Autophagy for 3 years. As soon as I understood it I started fasting between 2and 5 days at least once a month. I’m 76 and feel better all the time. Note: I just had the best 5 day fast ever, I learned so much for it. I am excited that my brain is noticeably better than 4 years ago.
@@bonsummers2657 oh thanks for asking. Well first and I had no problem with this was being FAT adapted and making my own ketones. Second days before I start a fast I eat liver, salmon,beef and a mixture of vegetables but all that just slightly more than normal. Start fast and immediately start with essential nutrients. Now this is what i finally understood, water, coffee and/or tea BUT this time I put Nothing in the drinks, nothing. What happened was I never craved or considered any bites of something, resulting in vary comfortable 5 days, 8 lbs off and refeeding was normal. And I only gained back 2 pounds in the next few days. No frenzy like usual. Ketones flowing and no craving. I’m starting again next week. Good 👍
@@4406bbldb Any comments/ measurements as to how much muscle mass was lost? Opinions vary widely about the muscle mass lost in fasting, so it would be great if people start measuring.
I was diagnosed with 3 clogged arteries and an aneurysm I started on 2000 IU of vitamin C , 2000 of Lysine and 500 -1000 of proline I added 2000 of chondroitin , every 6 -8 hours W/O any negative side effects.( most of these only stay in your system for 4-5 hours. So to get 24/7 benefits and avoid negative side effects… I then added glutathione normal dose and CoQ10 , only Omega 3 . I’ve been athletic, ate good . Stress, sleep , diet teas , etc … got to my CAD Fasting intermittent has been amazing and eating fruits/vegetables, then protein, then carbs or once in a while treat has changed my arteries to 29% over the last 6 months. I was at 70%,59% and 45% My Bad Dental implants were believed to be an ongoing I inflammatory problem that went to my heart Covid stopped all specialists from testing and procedures American Doctors never look at the connection between dental and heart and I personally believe due to medical insurance and not dental insurance is reversed in importance. Self help with videos!! Slowing down to a diet /intermittent fasting and sleeping is a lifestyle and life saving option Thanks Good luck and Thankyou for your videos
Thanks for sharing. It was very useful info. How did you come up with those supplements and dosages? Wasn't Intermenten fasting enough to get the result?
Id be curious to see if they have ever taken someone with arterial plaque and fasted them for a good long period of time . Not omad. Im talking , no eating for a week to a month. Safely supervised. Then checked the arteries after to see if the body removed the plaque or calcium deposits.
I did 7 days at the end of 2020 and in October 2021 went 14 days just water/electrolytes. I'd like to hope that the autophagy in these fasts was a good reboot of my system, only thing that puts me off doing a fast of that length again is the muscle loss, even a few days is bad as Dr Stephen Phinney points out. Took months to regain it and my road cycling suffered badly.
I’m 60 now and I’ve been on an IF regime to encourage autophagy for several months now and I’ve completely reversed two+ decades of high blood pressure and I would imagine, the clogged arteries like you’re describing here. My dad died with 7 stents and eventually a quad by-pass even though he was very active, ate “healthy” according to his docs, and was lean and muscular. I feel blessed to be alive during a time when these details about health are more widely understood. Thx. 😃
Here is the problem you need to address " I would imagine, the clogged arteries like you’re describing here" The problem is "imagine".... The doctor has given us nothing to prove there is any reversal of actual plaque. How about a study showing 70% plaque reversing to a 30% plaque or less.? Why not link us to that solid evidence if it exists. Until then, you need to think about the word "imagine". Why would you "imagine" it to work if no one shows a study of 20 or more with evidence of reversal. Why do people so easily believe things stated without solid proof. Show me the study and I'll read it, as should you and others.
@@delwoodkelp8590 my evidence is purely anecdotal but ALL my lab tests have shown massive improvements in a timespan of about 6 months, almost entirely back to my athletic teenage factory settings. I have no other way to describe what has happened to me as a result of my recent experience with fasting. What was described in this post makes sense to me based on my personal experience. That’s all I’m saying. Yes, I would also love to see more data on the subject buy I’m not going to deny what I feel in my own body just because YOU aren’t satisfied with the available data.
We never run out of "calories" (energy). We store over 50,000 calories in our body fat, able to be converted to energy (ATP). Autophagy's main purpose is not making energy but cleansing of damaged old cells.
73 years old with some coronary calcium CAC. Just wondering since calcium seals arterial damage (soft plaque) does the potential reduction of the plaque from the artery expose the original artery damage?
Thanks Doc. The Internet/TH-cam is a wonderful place to share such information. It really broadens the knowledge of people and advances mankind slowly but surely. And content like this is so good! I do extended fasts because as I understand it autophagy also works on clearing out the misfolded proteins that cause some neurological disorders - albeit not as aggressively as elsewhere in the body. I’ve also been doing OMAD for about a month now so hopefully it’s helping to keep my brain in order.
❤Dr, I have been fasting an average of 18-20 hours a day for 7 years. I have recently been diagnosed with High LIPOPROTEIN a and APOb. When I had my Scan done I had ZERO PLAQUE in my arteries. I truly believe it’s from fasting! Thank you 🙏🏼 So very much for sharing this! The confirmation is quite powerful and propelling
wow.... this is an excellent video! This is the sort of knowledge that could save your life and enhance quality of life as well. looking forward to the follow up! you're a great teacher... thank you!!
What you people have to start covering with this autophagy and self-healing thing, is the extraordinary and absurd amounts of energy that courses through your veins once you have completely healed your body and what you're going to do with that excess energy. I thought about jumping up and slapping the moon out of orbit.
🎯 Key Takeaways for quick navigation: 00:28 🔄 *Autofagia: Proceso celular donde las células se "comen a sí mismas" para obtener energía cuando no hay suficientes fuentes externas de calorías.* 01:09 🧬 *Rapamicina y mTOR: La rapamicina estimula la autofagia y afecta mTOR, un objetivo importante en la regulación del proceso.* 02:33 🔄 *Lisosomas y Autofagia: La actividad lisosomal es crucial para la destrucción de organelos envejecidos, especialmente las mitocondrias, mejorando la salud celular.* 04:23 🛡️ *Autofagia y Enfermedades Vasculares: La autofagia desempeña un papel crítico en enfermedades vasculares como la aterosclerosis y bloquear mTOR puede ser beneficioso.* 05:57 🔄 *Transporte Inverso de Colesterol: La autofagia ayuda en el transporte inverso de colesterol, llevándolo desde las células de vuelta al hígado, contribuyendo a la salud cardiovascular.* 06:52 🔍 *Autofagia y Placas Arteriales: La autofagia ayuda a descomponer las células inmunológicas que han "comido" placas arteriales, contribuyendo a la gestión de las enfermedades cardiovasculares.* Made with HARPA AI
I am a firm believer in this concept. I am using low carb/Keto and intermittent fasting toward these goals. Also helps with diabetes. The only problem I had was when I took a probiotic
@directajith This is specific to Akermensia. A butyric producing prebiotic that can sustain on mucus lining but can sometimes overgrow. It might be useful for people who eat a lot of fiber and carbs. This was when I was exploring lowering blood glucose through prebiotic strains. I had some success with kefir Low temp paterized style also called vat pasterized.
@@chrisnamaste3572 No..lol... Keto is not inflammatory. A keto diet is also known as a fasting mimicking diet. You get all the benefits of fasting. While you still eat. What is inflammatory is sugar, high levels of insulin, and any plant you can name, also seed oils, and vegetable oils.
I like this doctor more when he was with a big piace of paper, and I cud understand his points more. Now a day, I try to see the points first before committing to the whole talk, but very difficult to find any summary. Nice title, but I am just reading the viewers feedback.... From Singapore
Hi Doc from the U.K. … can’t find anything on your channel regarding Nattokinase .. would love to hear your views on what , if any , role this can play in cardiac/arterial health.
Your interesting talk has inspired me to get back to my regular fasting routine. I just need to learn how to mesh it with my weightlifting. I could be wrong but last I heard, it takes at least 72hrs of fasting to achieve autophagy.
According to Dr Paul Mason the plaque in arteries are more likely comprised of phyto-sterol as opposed to chole-sterol. Which suggests that they are more likely coming from plant based oils. Of course we’re all aware of the dangers of seed oils but perhaps it’s wise to limit our use of other plant based fats such as coconut, avocado and olive. All of which certainly have their own benefits of course.
Hello Dr brewer I watched your videos can u make a detailed video on how to properly take all supplements you mentioned in your videos along with autophagy and exercise
If you fast for 48 hours once a week and 72 hours once a month you're muscles and bones get stronger - Not weaker. That's what Autophagy and Ketones does.
It would depend for sure. I do believe there are studies that show you can build or maintain muscle on a fast as long as you do some resistance exercise. However, I don't recall them making a point about whether these people were metabolically flexible or not. So it would seem in theory, if your body wants mainly glucose for fuel and not fatty acids then you might be turning protien from muscles into glucose. But I honestly don't know the answer to this. I just know you don't necessarily lose muscle mass while fasting in the short term, 72 hours or less.
You really won’t, if you’re doing an extended fast once every 1-3 months (which is what most advocate) and shorter 24 hour fast every week or two. Muscle mass depends far more on having a healthy baseline in three areas: 1) regular resistance training 2) hormonal health (and HRT, if necessary). 3) Optimal protein intake (0.75-1 gram per pound of body weight).
Maybe CVD is just slightly more inflammation than autophagy. With most people having way too much inflammation and with eating 24/7 and 365 days a year autophagy being very low, it's no wonder mist get sick.
It is all about high insulin. Insulin dysregulates the immune system meaning that individual components of the immune system like LDL-particles, monocytes/macrophages, fibroblatst and fribrinoges (which are all involved in atherosclerosis) stop working effectively but there too many of them / they are behaving too chaotic / are too "rigid" etc. Lowering insulin alone (besides activating autophagy by it's own) will automatically lead to a better healing of the preexisting plaque...
Hello, an effective method to promote autophagy is to take one Inpefa (Sotagliflozin) tablet of 200 mg daily, 30 minutes before the first meal. It requires a doctor's prescription. This antidiabetic medication for type 2 diabetes is reputed to be highly effective. It works by blocking sugar absorption and preventing blood sugar spikes. I experienced a weight loss of 10 pounds in just two to three weeks without significant dietary effort, and my blood pressure also returned to normal.
I’m a bit confused about the relationship between MTOR & MIBK. I assume these are two different proteins that work opposite of one another according to what studies have shown. What was written is that it is most important to maintain a balance between those two proteins. But in your webinar, you made it sound like we should not have any MTOR in our metabolism but the studies indicate that we need both but they must be balanced! Can you please make any corrections about these statements and explain the metabolic mechanisms of the two opposing proteins? In the same vain, most physicians make it sound like we don’t need any omega 6 fats to exist in our bodies or our foods but in reality, in addition to omega 3 fatty acids, we probably need an equal amount of omega 6 fatty acids which in my opinion does not get translated to the public in that way. Much of the public most likely thinks that omega 6 fatty acids are poison to our bodies because you are always emphasizing the need to increase our omega 3 intake. Much of the public doesn’t understand that we need both types of fatty acids but ideally at a 1:1 ratio if I recall. Likewise, we also require both MTOR (mamalaen mechanistic target of repamycin) & MIBK which i believe is a cellular enzyme since it’s a “kinase” at about equal levels but I will hope that you can devote one whole webinar to this very fascinating and dynamic equilibrium between these two proteins and whether more of one of them is required in certain metabolic circumstances as well as certain metabolic pathways. Thank you for your devotion!!!
Hi Dr.Brewer, I’m new to your channel. Not by choice😂. I love your sense of humor. Recently the CT scan shown I have a small blood clot in my common carotid arteries. My brain is still trying to process all these information.
The effect by directly growing new neurons will be very limited. But fasting mens also high ketone levels and these will existing neurons make function much better and even let new synapses to grow. And what is more important, the mitophagy (the autophagy of the mitochondria) will make neurons more effective
You could try R-ALA and Lion's Mane mushroom extract. I use the Jarrow brand for the R-ALA, make sure the Lion's Mane mushroom extract is from fruiting bodies, not from mycelium. Good luck to you.
@@dethbefodisco3221..I've heard that aswel..i also heard that upping B1 or thiamine and cutting out the sugars and omegas 6 and 9 will improve alzheimers ..
What I don’t understand is why cardiologists say you can’t reverse the plaque or clogged arteries, all the major hospital studies say you can’t reverse it, yet these doctors say oh yeah take some supplements and it’s gone
One is pushing medication that requires a license, the other is pushing supplements. You can only try learning more about the stuff through anecdotes and studies where there aren't any conflicts of interest.
Dr Brewer, what about cavadex? Do you know this drug? They are saying that this drug will improve arterial disease. I would like to hear your opinion about this subject. Congrats
Best way to induce autophagy is with extended fasting. Fasting is much much easier starting from a ketogenic state. Otherwise you have to spend 2 or 3 days uncomfortably hungry inducing ketosis. I guess you could say ketosis is a prerequisite for autophagy. It definitely is for successful fasting. So Dr Brewer is valadating those of us who eat low carb and fast to induce autophagy.
Actually, the best way to induce autophagy is with exercise. I used to think it was with fasting too, but it's now known that exercise induces it much more than fasting.
I do both..24 - 30 hr. fast , then go just walk on a treadmill for 30-45 min (HITT) method. Go pee on a ketosis stick .BOOM..(purple) enjoy deep ketosis. Make sure you break with 1 tbl. spoon MCT C8 oil first & bone broth w/ pink Hyminalain salt. So you don't drop into keto flu ..✌️Fast for life Keto lovers !!
Really….I have been doing 18 - 6 for past three years and just had an heart attack 2 weeks ago. Doc told me that my LAD was 95 percent blocked….am really confused as to who to listen to…
@@rizwanshahzad3653 are you a diabetic, smoker, had a history of CAD? If you start to take statin and studies show that calcification of the arteries progress so what do you think will happen to the 95% Left Anterior Descending blockage? In every calcification of the artery insulin resistance also is present. Lower carbs, eat more vegetables and continue your 18-6 or maybe do once a day meal. I would do everything thru my diet to change the heart condition. do blood work regularly. lose weight, do moderate exercise and go to your doctor for blood work and even heart scan. I will never compromise my heart thru the statins that have many more side effects.
Just liked and subbed. Great video. Very interested in controlling plaque that I know has begun to develop. Doctors just want me on statins, which I refuse.
Dr. Brewer do you recommend a protocol? ie., 2 day water fast per month or maybe more than 2 days. I am guessing at least one day - and from what I know of autophogy you can’t have a molecule of food.
Please help me, I have angina and chest pressure when I work out and are stressed. 2020 I had extreme chest pressure and could not breathe, my D-dimer was 1,6 and I had several troponin measurements (since I was at the ER repeatedly) and the highest was 9 (and one
visit prevmedhealth.com we will be happy to get you enrolled in our program
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I'm not a doctor, but look into vasodilators that produce or stimulate nitric oxide. Nitric oxide expands arteries and it can do so rapidly. However there are cautions with any new supplement that you try and you shouldn't mix with already prescribed medicine unless your doctor approves you to do so.
Any info I can review on how long a person needs to fast to get into autophagy for cholesterol to be gobbled up? I’m sure not everyone is the same, but a range would be helpful. I’m having high cholesterol issues and fast 16-18 hrs per day with occasional 24 hr. Cholesterol still high. I hope to get a calcium score soon. Not as easy in Canada as in USA, but doable.
I’m on 100% plant based. I also eat 2 bowls of raw oats and soy milk per day. I have 4 moderate blockages. My LDL has gone from 3.3 to 1.6 and my total, from 6.6 to 4.1 (uk measurements. Multiply by 38) - I take a statin too. I’m convinced the oatmeal haas played a big part. Try and add it to your diet
This all sounds all well and good, but do you want to be dissolving old plaque formations if they contain unstable (liquid/hot) plaque, thereby risking the formation of a potential thrombosis-induced clot?
" do you want to be dissolving old plaque formations" yes "risking the formation of a potential thrombosis-induced clot" very unlinkely. blood-clotting ist very limited in fasted state... Actually, it is the high insulin which makes blood-clotting became "hyperactive"...
@@btudrus The problem of clotting is when unstable "hot" plague ruptures through the endothelial layer because it WILL cause a clot. The concern is disturbing unstable plaque. Does Vit C dissolve the calcium without causing the risk of a plaque rupture?
One has to get rid of inflammation as part of arterial cleansing ie. Excessive carbohydrate intake has to stop as well as hyperihnculinemia needs to be addressed through fasting…
This is a really fast overview and I think it needs 30 minutes or one hour to really explain it. I didn't really understand much of this and I really want to.
Agree. So bottom line is to get these enzymes in the blood system to eat-up cholesterol deposits? And to do that take rapomycin? (sp?) And fast for 17 hours?
Here is a very tough autophagy questio. I have ALS and I ha the C9ORF72 gene. I do 24 hour autophagy every couple months. Can autphagy get rid of the radical protein that attacks the motor neurons?
I don't know what the impact is of your genetics, but if I were you, I'd be fasting 3 days every month and take CoQ10, R-ALA, vitamin D3 & C and Lion's Mane Mushroom extract. Good luck to you.
@normastone1044 I take CoQ10 a lot plus D2, B7,B12, C. I also take Lion's Mane and moringa. I will be starting 24 and 48 hour fasting next month. I have bad fingers so disregard the thumb down. Thanks for the advice.
@@jeffsingleton7330 Recently, I badly injured my hamstring and developed complications, resulting in some nerve damage that affects walking normally. I started taking R-ALA and have been improving steadily over the last 5 weeks. Just something for you to consider.
@@jeffsingleton7330I would also be looking into taking phosphatidyl serine, manganese, copper, zinc, krill oil, cod liver oil, optimize vitamin D levels >50, ketogenic diet, thunder god vine, matcha tea for ECGC and l-thianine
@@normastone1044Does the fast need to be a water fast, or one where you can have teas and or black coffee? I’ve heard people say that if it isn’t a water fast, you don’t get all the benefits. I’m a 54 year old female and recently received a calcium score of 89 showing plaque in my arteries, as well as mitral valve regurgitation, tricuspid valve regurgitation and mild dilation (right side of heart). I’ve been put on a statin and told I need to take this as a preventative for the rest of my life.
The body isn’t stupid, something that’s not meant to be there will and can be removed by the system, but first the offending cause needs to be stopped. Once you find the cause and cease it, the body will do what it knows to do.
I fast every day! I usually eat 2 meals. My first one usually around 11 or 12. I do once an while a 24 hr. Anyway I had 2 A/fib and my last one my doctor told me I have 20% clogged arteries! I don’t drink or smoke!
What are the macros of those two meals? are you making sure you are getting enough nutrients, vitamins, and minerals in those meals? Magnesium can help some people with Afib.
Great, Video. Muslim are required to fast for 30 days each year during the month of Ramadan. It cleanses the body once a year from all the accumulated things that should not be there.
No hospital in the Philippines offers medically supervised prolonged water fast/autophagy. Please have an autophagy therapy and do it in one of our beaches in the Philippines
10 stories at a time, but none till the end. it's like my name is i am not going to detalize, I am from I am not going to go into this rabit hole, so now you know me well, let's whatch another video like this so you know more...
I find it easier to trust those who have no financial stake in my health. If everyone was healthy, what would happen to drug companies and major medical institutions?
Your story Is very interesting! Could you please describe it in details so that we, people with some plague in arteries can apply it for ourselves. Thank you!
Sorry Nick but following this advice and with subsequent lifestyle changes for over the past two years has resulted in not only health improvement but also the elimination of pharmaceutical drugs along with their subsequent side effects and further prescriptions to contend with those side effects. But each to their own.
@@uslanja For what reason did you need the pharmaceuticals? What exactly allowed you to get off of the drugs? How did the intervention cure your ailments?
@@uslanja. Good for you. Am about to begin this protocol myself. Been an avid faster most my life, it really can cure if not at least accelerate healing.
Nobody as yet really understands exactly how autophagy works in humans. Most studies are done on laboratory animals. We know it happens, but the exact details are still a mystery . 🤔💭
welll….. AGAIN!…. a video of yours without CONCLUSION („what should i DO for more autophagy?“),…. so you avoid again any CLEAR advice….. (like always) …. sorry for maybe a little bit tough critique… 😢
That is the most bogus comment there is. Search humans were apex predators for two million years. Hypercarnivores. Consider this. Humans did not domesticate an animal that could pull a plow until 6,000 years ago. We never ate plants in abundance until extremely recently in our history and we don’t have the gut for it.
Many thanks for sharing another great video! Many thanks for sharing Dr Brewer!
Thank you very much
@@PrevMedHealth No thank you to you for freely sharing such valuable information, much appreciated
I’ve been fasting for Autophagy for 3 years. As soon as I understood it I started fasting between 2and 5 days at least once a month. I’m 76 and feel better all the time. Note: I just had the best 5 day fast ever, I learned so much for it. I am excited that my brain is noticeably better than 4 years ago.
You learned so much? Tell us what you learned.
So excited for you.
Please share impt points.
@@bonsummers2657 He learned that he was able to sustain a 5-day fast. 😉
@@bonsummers2657 oh thanks for asking. Well first and I had no problem with this was being FAT adapted and making my own ketones. Second days before I start a fast I eat liver, salmon,beef and a mixture of vegetables but all that just slightly more than normal. Start fast and immediately start with essential nutrients. Now this is what i finally understood, water, coffee and/or tea BUT this time I put Nothing in the drinks, nothing. What happened was I never craved or considered any bites of something, resulting in vary comfortable 5 days, 8 lbs off and refeeding was normal. And I only gained back 2 pounds in the next few days. No frenzy like usual. Ketones flowing and no craving. I’m starting again next week. Good 👍
@@4406bbldb Any comments/ measurements as to how much muscle mass was lost? Opinions vary widely about the muscle mass lost in fasting, so it would be great if people start measuring.
I was diagnosed with 3 clogged arteries and an aneurysm
I started on 2000 IU of vitamin C , 2000 of Lysine and 500 -1000 of proline
I added 2000 of chondroitin , every 6 -8 hours W/O any negative side effects.( most of these only stay in your system for 4-5 hours. So to get 24/7 benefits and avoid negative side effects… I then added glutathione normal dose and CoQ10 , only Omega 3 .
I’ve been athletic, ate good .
Stress, sleep , diet teas , etc … got to my CAD
Fasting intermittent has been amazing
and eating fruits/vegetables, then protein, then carbs or once in a while treat has changed my arteries to 29% over the last 6 months.
I was at 70%,59% and 45%
My Bad Dental implants were believed to be an ongoing I inflammatory problem that went to my heart
Covid stopped all specialists from testing and procedures
American Doctors never look at the connection between dental and heart and I personally believe due to medical insurance and not dental insurance is reversed in importance.
Self help with videos!!
Slowing down to a diet /intermittent fasting and sleeping is a lifestyle and life saving option
Thanks
Good luck and Thankyou for your videos
I did keto years ago. Since I stopped. I had 2A/fib and my doctor told me I have. 20% clogged arteries! I’m looking in doing plant based?
@@geno5169 Meat isn't the cause if your problem, processes carbs and sugar is. Do you do any resistance training?
Thanks for sharing. It was very useful info. How did you come up with those supplements and dosages? Wasn't Intermenten fasting enough to get the result?
@@geno5169good luck you will need it
@@paulhailey2537 WOW, unbelievable. I'll postpond my surgery to try this. Was the eggs the only meal you had? please share. I'm really in trouble
Id be curious to see if they have ever taken someone with arterial plaque and fasted them for a good long period of time . Not omad. Im talking , no eating for a week to a month. Safely supervised. Then checked the arteries after to see if the body removed the plaque or calcium deposits.
This
I did 7 days at the end of 2020 and in October 2021 went 14 days just water/electrolytes. I'd like to hope that the autophagy in these fasts was a good reboot of my system, only thing that puts me off doing a fast of that length again is the muscle loss, even a few days is bad as Dr Stephen Phinney points out. Took months to regain it and my road cycling suffered badly.
@@SET12DSP protocol?
@@SET12DSPare you a real person or are you advertising?
My brother wants me to start this but I’m a bit Leary of it. It’s not at all cheap!!
@@SET12DSPdid you take any statins?
I’m 60 now and I’ve been on an IF regime to encourage autophagy for several months now and I’ve completely reversed two+ decades of high blood pressure and I would imagine, the clogged arteries like you’re describing here. My dad died with 7 stents and eventually a quad by-pass even though he was very active, ate “healthy” according to his docs, and was lean and muscular. I feel blessed to be alive during a time when these details about health are more widely understood. Thx. 😃
Here is the problem you need to address " I would imagine, the clogged arteries like you’re describing here"
The problem is "imagine".... The doctor has given us nothing to prove there is any reversal of actual plaque.
How about a study showing 70% plaque reversing to a 30% plaque or less.?
Why not link us to that solid evidence if it exists. Until then, you need to think about the word "imagine".
Why would you "imagine" it to work if no one shows a study of 20 or more with evidence of reversal.
Why do people so easily believe things stated without solid proof.
Show me the study and I'll read it, as should you and others.
@@delwoodkelp8590 👍👌That's exactly what I thought!
@@delwoodkelp8590 my evidence is purely anecdotal but ALL my lab tests have shown massive improvements in a timespan of about 6 months, almost entirely back to my athletic teenage factory settings. I have no other way to describe what has happened to me as a result of my recent experience with fasting. What was described in this post makes sense to me based on my personal experience. That’s all I’m saying. Yes, I would also love to see more data on the subject buy I’m not going to deny what I feel in my own body just because YOU aren’t satisfied with the available data.
@@delwoodkelp8590Hasn’t Dr Brewer lowered his own plaque?
@@delwoodkelp8590he does have an older clip with evidence of how over 2 years he reversed his.plaque
We never run out of "calories" (energy). We store over 50,000 calories in our body fat, able to be converted to energy (ATP). Autophagy's main purpose is not making energy but cleansing of damaged old cells.
73 years old with some coronary calcium CAC. Just wondering since calcium seals arterial damage (soft plaque) does the potential reduction of the plaque from the artery expose the original artery damage?
Thanks Doc. The Internet/TH-cam is a wonderful place to share such information. It really broadens the knowledge of people and advances mankind slowly but surely. And content like this is so good! I do extended fasts because as I understand it autophagy also works on clearing out the misfolded proteins that cause some neurological disorders - albeit not as aggressively as elsewhere in the body. I’ve also been doing OMAD for about a month now so hopefully it’s helping to keep my brain in order.
❤Dr, I have been fasting an average of
18-20 hours a day for
7 years. I have recently been diagnosed with
High LIPOPROTEIN a
and APOb.
When I had my Scan done I had ZERO PLAQUE in my arteries.
I truly believe it’s from fasting! Thank you 🙏🏼 So very much for sharing this! The confirmation is quite powerful and propelling
What scan?
Sorry that means nothing. Soft plaque is the killer so 0 score is 0 score for hard plaque
wow.... this is an excellent video!
This is the sort of knowledge that could save your life and enhance quality of life as well.
looking forward to the follow up!
you're a great teacher...
thank you!!
👍
What you people have to start covering with this autophagy and self-healing thing, is the extraordinary and absurd amounts of energy that courses through your veins once you have completely healed your body and what you're going to do with that excess energy. I thought about jumping up and slapping the moon out of orbit.
🎯 Key Takeaways for quick navigation:
00:28 🔄 *Autofagia: Proceso celular donde las células se "comen a sí mismas" para obtener energía cuando no hay suficientes fuentes externas de calorías.*
01:09 🧬 *Rapamicina y mTOR: La rapamicina estimula la autofagia y afecta mTOR, un objetivo importante en la regulación del proceso.*
02:33 🔄 *Lisosomas y Autofagia: La actividad lisosomal es crucial para la destrucción de organelos envejecidos, especialmente las mitocondrias, mejorando la salud celular.*
04:23 🛡️ *Autofagia y Enfermedades Vasculares: La autofagia desempeña un papel crítico en enfermedades vasculares como la aterosclerosis y bloquear mTOR puede ser beneficioso.*
05:57 🔄 *Transporte Inverso de Colesterol: La autofagia ayuda en el transporte inverso de colesterol, llevándolo desde las células de vuelta al hígado, contribuyendo a la salud cardiovascular.*
06:52 🔍 *Autofagia y Placas Arteriales: La autofagia ayuda a descomponer las células inmunológicas que han "comido" placas arteriales, contribuyendo a la gestión de las enfermedades cardiovasculares.*
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I am a firm believer in this concept. I am using low carb/Keto and intermittent fasting toward these goals. Also helps with diabetes. The only problem I had was when I took a probiotic
what was the issue with probiotic
@directajith
This is specific to Akermensia. A butyric producing prebiotic that can sustain on mucus lining but can sometimes overgrow. It might be useful for people who eat a lot of fiber and carbs.
This was when I was exploring lowering blood glucose through prebiotic strains. I had some success with kefir Low temp paterized style also called vat pasterized.
Inflammation is a key issue and doing a "Keto" diet can be highly inflamatory.
@@chrisnamaste3572
How is keto diet highly inflamatory?
@@chrisnamaste3572 No..lol... Keto is not inflammatory. A keto diet is also known as a fasting mimicking diet. You get all the benefits of fasting. While you still eat. What is inflammatory is sugar, high levels of insulin, and any plant you can name, also seed oils, and vegetable oils.
Autopaghy (IF) with low carb eater should be faster to reverse the plugging.
I like this doctor more when he was with a big piace of paper, and I cud understand his points more. Now a day, I try to see the points first before committing to the whole talk, but very difficult to find any summary.
Nice title, but I am just reading the viewers feedback....
From Singapore
Hope prolonged fasting will be tested, 7 days, 14 days, 30days, etc. Also for other chronic diseases
So we need to promote the macrophages and lysosomes to remove the plaque.
keeping mTOR levels low seems to contradict animal based diets for protein.
Hi Doc from the U.K. … can’t find anything on your channel regarding Nattokinase .. would love to hear your views on what , if any , role this can play in cardiac/arterial health.
We eat too much and too often. It makes sense now.
Your interesting talk has inspired me to get back to my regular fasting routine. I just need to learn how to mesh it with my weightlifting. I could be wrong but last I heard, it takes at least 72hrs of fasting to achieve autophagy.
You can reach autophagy after around 17hrs. The longer the better but you can reach autophagy in shorter time frames.
@@TXDHC No shot you'll reach spikes in autophagy at 17h if you eat a carby diet lol
@@TXDHC thanks, I'll have to look into that. 17 hrs is easy. Just skip breakfast.
@@Bankai90 not sure what you’re trying to say.
@@Bankai90low carb
According to Dr Paul Mason the plaque in arteries are more likely comprised of phyto-sterol as opposed to chole-sterol. Which suggests that they are more likely coming from plant based oils.
Of course we’re all aware of the dangers of seed oils but perhaps it’s wise to limit our use of other plant based fats such as coconut, avocado and olive. All of which certainly have their own benefits of course.
Thank you for sharing that
Key to health & wellness: Eat JUST enough to survive... not a bite more!
When lysosomes start breaking down plaque is it dangerous, meaning can a piece break off because of it and cause heart attacks?
My thinking is that it is more of a dissolve process rather than a breaking pieces off. I am not a doctor though. Best
@@tomm2812 that's what I was thinking also but just wanted to verify. Peace 🙏
All the stuff they told me as I dozed through biology class...that I finalize realize matters... :)
Does unsweetened almond milk in a iced coffee break a fast?
Yes it does
All this technology. So what is recommended?
Hello Dr brewer I watched your videos can u make a detailed video on how to properly take all supplements you mentioned in your videos along with autophagy and exercise
I can understand this. My issue here is that it we fast for to long. We will lose muscle mass also no?
If you fast for 48 hours once a week and 72 hours once a month you're muscles and bones get stronger - Not weaker. That's what Autophagy and Ketones does.
It would depend for sure. I do believe there are studies that show you can build or maintain muscle on a fast as long as you do some resistance exercise. However, I don't recall them making a point about whether these people were metabolically flexible or not. So it would seem in theory, if your body wants mainly glucose for fuel and not fatty acids then you might be turning protien from muscles into glucose. But I honestly don't know the answer to this. I just know you don't necessarily lose muscle mass while fasting in the short term, 72 hours or less.
You really won’t, if you’re doing an extended fast once every 1-3 months (which is what most advocate) and shorter 24 hour fast every week or two. Muscle mass depends far more on having a healthy baseline in three areas: 1) regular resistance training 2) hormonal health (and HRT, if necessary). 3) Optimal protein intake (0.75-1 gram per pound of body weight).
@@adelarsen9776 yeah, that's not how it works.
Maybe CVD is just slightly more inflammation than autophagy. With most people having way too much inflammation and with eating 24/7 and 365 days a year autophagy being very low, it's no wonder mist get sick.
It is all about high insulin. Insulin dysregulates the immune system meaning that individual components of the immune system like LDL-particles, monocytes/macrophages, fibroblatst and fribrinoges (which are all involved in atherosclerosis) stop working effectively but there too many of them / they are behaving too chaotic / are too "rigid" etc. Lowering insulin alone (besides activating autophagy by it's own) will automatically lead to a better healing of the preexisting plaque...
Hello, an effective method to promote autophagy is to take one Inpefa (Sotagliflozin) tablet of 200 mg daily, 30 minutes before the first meal. It requires a doctor's prescription. This antidiabetic medication for type 2 diabetes is reputed to be highly effective. It works by blocking sugar absorption and preventing blood sugar spikes. I experienced a weight loss of 10 pounds in just two to three weeks without significant dietary effort, and my blood pressure also returned to normal.
I'd love to fast, but I don't have enough food to do it....does that make sense?
I’m a bit confused about the relationship between MTOR & MIBK. I assume these are two different proteins that work opposite of one another according to what studies have shown. What was written is that it is most important to maintain a balance between those two proteins. But in your webinar, you made it sound like we should not have any MTOR in our metabolism but the studies indicate that we need both but they must be balanced! Can you please make any corrections about these statements and explain the metabolic mechanisms of the two opposing proteins? In the same vain, most physicians make it sound like we don’t need any omega 6 fats to exist in our bodies or our foods but in reality, in addition to omega 3 fatty acids, we probably need an equal amount of omega 6 fatty acids which in my opinion does not get translated to the public in that way. Much of the public most likely thinks that omega 6 fatty acids are poison to our bodies because you are always emphasizing the need to increase our omega 3 intake. Much of the public doesn’t understand that we need both types of fatty acids but ideally at a 1:1 ratio if I recall. Likewise, we also require both MTOR (mamalaen mechanistic target of repamycin) & MIBK which i believe is a cellular enzyme since it’s a “kinase” at about equal levels but I will hope that you can devote one whole webinar to this very fascinating and dynamic equilibrium between these two proteins and whether more of one of them is required in certain metabolic circumstances as well as certain metabolic pathways. Thank you for your devotion!!!
How long do you have the most plaque and artery removal? Two weeks?
ok so specifics tho? like...
Hi Dr.Brewer, I’m new to your channel. Not by choice😂. I love your sense of humor.
Recently the CT scan shown I have a small blood clot in my common carotid arteries. My brain is still trying to process all these information.
my question is how long does my body need to be in autophagy in order to reverse arterial plaque?
Will virgin olive oil help with clogged arteries?
Short answer yes!
@@PrevMedHealth Hi Doc enjoy your videos and a doctor involved in prevention medicine is refreshing. Thanks so much for your help.
What is the reference that contains the figure shown at 4:51 in the video?
Anyone? Is there a Autophagy timeline to achieve full cellular cleansing?
Is it true you can obtain atophagy in 17 hours?
Why is the plaque in the figure @6:20 not inside of the artery wall thus compressing the lumen? (narrowing it)
Could fasting and autophagy help a paralyzed stroke patient by recycling and regenerating her brain 🧠 cells ?
The effect by directly growing new neurons will be very limited.
But fasting mens also high ketone levels and these will existing neurons make function much better and even let new synapses to grow.
And what is more important, the mitophagy (the autophagy of the mitochondria) will make neurons more effective
You could try R-ALA and Lion's Mane mushroom extract. I use the Jarrow brand for the R-ALA, make sure the Lion's Mane mushroom extract is from fruiting bodies, not from mycelium. Good luck to you.
Mct oil
What about Alzheimer’s plaque? Can that be reversed with autophagy ? So no sweets and lo calorie intake for Alzheimer’s patients?
Not low calorie: instead, use Low carb an fasting for autophagy
I've heard them call Alzheimer type 3 diabetes
@@dethbefodisco3221..I've heard that aswel..i also heard that upping B1 or thiamine and cutting out the sugars and omegas 6 and 9 will improve alzheimers ..
Type 3 diabetes is definitely improved with real fasting
Does reverse cholesterol transport work for plaque _underneath_ hardened calcium? Or does it only work for soft plaque?
Is there a part 2?
Excellent 🥹❤️👑 thank you Doc! Greetings from Germany
What I don’t understand is why cardiologists say you can’t reverse the plaque or clogged arteries, all the major hospital studies say you can’t reverse it, yet these doctors say oh yeah take some supplements and it’s gone
Ford reversed 20 years of plaque in 20 months. Has videos with the proof.
exactly. there is something wrong
One is pushing medication that requires a license, the other is pushing supplements. You can only try learning more about the stuff through anecdotes and studies where there aren't any conflicts of interest.
Dr Brewer, what about cavadex? Do you know this drug? They are saying that this drug will improve arterial disease. I would like to hear your opinion about this subject. Congrats
Best way to induce autophagy is with extended fasting. Fasting is much much easier starting from a ketogenic state. Otherwise you have to spend 2 or 3 days uncomfortably hungry inducing ketosis. I guess you could say ketosis is a prerequisite for autophagy. It definitely is for successful fasting.
So Dr Brewer is valadating those of us who eat low carb and fast to induce autophagy.
Actually, the best way to induce autophagy is with exercise. I used to think it was with fasting too, but it's now known that exercise induces it much more than fasting.
Exogenous spermadinne stimulates autophagy to a greater degree than fasting
I do both..24 - 30 hr. fast , then go just walk on a treadmill for 30-45 min (HITT) method. Go pee on a ketosis stick
.BOOM..(purple) enjoy deep ketosis. Make sure you break with 1 tbl. spoon MCT C8 oil first & bone broth w/ pink Hyminalain salt. So you don't drop into keto flu ..✌️Fast for life Keto lovers !!
@@Markhypnosis1 What kind of exercise?
It would be nice if doctor provided links to papers cited in the video or at least doi signature
I agree
When you putting out part 2?
So if you can initiate autophagy thru fasting then you dont need cholesterol pills to remove plaques in your arteries
Really….I have been doing 18 - 6 for past three years and just had an heart attack 2 weeks ago. Doc told me that my LAD was 95 percent blocked….am really confused as to who to listen to…
@@rizwanshahzad3653 are you a diabetic, smoker, had a history of CAD? If you start to take statin and studies show that calcification of the arteries progress so what do you think will happen to the 95% Left Anterior Descending blockage? In every calcification of the artery insulin resistance also is present. Lower carbs, eat more vegetables and continue your 18-6 or maybe do once a day meal. I would do everything thru my diet to change the heart condition. do blood work regularly. lose weight, do moderate exercise and go to your doctor for blood work and even heart scan. I will never compromise my heart thru the statins that have many more side effects.
@@rizwanshahzad3653 can you share your diet as well. i am on same track
Has anyone ever shrunk an ascending aortic aneurism with a green diet?
Just liked and subbed. Great video. Very interested in controlling plaque that I know has begun to develop. Doctors just want me on statins, which I refuse.
Thank You!
Keep holding out. Don't take statins whatever you do! 🙏
Dr. Brewer do you recommend a protocol? ie., 2 day water fast per month or maybe more than 2 days.
I am guessing at least one day - and from what I know of autophogy you can’t have a molecule of food.
If you're on a high carb diet you prob need 4-5days. 1-3days if keto lol. 2 days is nothing
@@Bankai90 thanks, I’m keto do a day is a breeze.
@@Bankai90 So 2 days fasting if my current diet involves eating nothing???
@@jobl5505anyway if you are on keto you are at cardiac risk , not in short term but in the middle or long term.
72 hours of dry fasting that is the only time autophagy works
Looking forward to Part 2.
Aren't organelles a musical group?
Please help me, I have angina and chest pressure when I work out and are stressed. 2020 I had extreme chest pressure and could not breathe, my D-dimer was 1,6 and I had several troponin measurements (since I was at the ER repeatedly) and the highest was 9 (and one
visit prevmedhealth.com we will be happy to get you enrolled in our program
I'm not a doctor, but look into vasodilators that produce or stimulate nitric oxide. Nitric oxide expands arteries and it can do so rapidly. However there are cautions with any new supplement that you try and you shouldn't mix with already prescribed medicine unless your doctor approves you to do so.
Any info I can review on how long a person needs to fast to get into autophagy for cholesterol to be gobbled up? I’m sure not everyone is the same, but a range would be helpful. I’m having high cholesterol issues and fast 16-18 hrs per day with occasional 24 hr. Cholesterol still high. I hope to get a calcium score soon. Not as easy in Canada as in USA, but doable.
I’m on 100% plant based. I also eat 2 bowls of raw oats and soy milk per day. I have 4 moderate blockages. My LDL has gone from 3.3 to 1.6 and my total, from 6.6 to 4.1 (uk measurements. Multiply by 38) - I take a statin too. I’m convinced the oatmeal haas played a big part. Try and add it to your diet
This is in 6 weeks by the way
This is the function of hdl cholesterol. It seems that higher hdl would be beneficial, rather than mTOR. Thoughts?
what you mean by "taking mTOR". You cannot take mTOR. You can activate it (e.g. by high insulin) or deactivate it (e.g. by prolonged fasting)...
@@btudrus thank you. Correction made.
This all sounds all well and good, but do you want to be dissolving old plaque formations if they contain unstable (liquid/hot) plaque, thereby risking the formation of a potential thrombosis-induced clot?
" do you want to be dissolving old plaque formations"
yes
"risking the formation of a potential thrombosis-induced clot"
very unlinkely. blood-clotting ist very limited in fasted state... Actually, it is the high insulin which makes blood-clotting became "hyperactive"...
Think in terms of shrinking and reducing plaque burden. Therby reducing the chance of rupture.
@@btudrus The problem of clotting is when unstable "hot" plague ruptures through the endothelial layer because it WILL cause a clot. The concern is disturbing unstable plaque. Does Vit C dissolve the calcium without causing the risk of a plaque rupture?
@@venkateshvelaga8850 That answers my question. Thanks.
One has to get rid of inflammation as part of arterial cleansing ie. Excessive carbohydrate intake has to stop as well as hyperihnculinemia needs to be addressed through fasting…
This is a really fast overview and I think it needs 30 minutes or one hour to really explain it. I didn't really understand much of this and I really want to.
Agree. So bottom line is to get these enzymes in the blood system to eat-up cholesterol deposits? And to do that take rapomycin? (sp?) And fast for 17 hours?
This was part 1…
Just do dry fasting at least 48 to 72 hours
cell walls in humans?!
Here is a very tough autophagy questio. I have ALS and I ha the C9ORF72 gene. I do 24 hour autophagy every couple months. Can autphagy get rid of the radical protein that attacks the motor neurons?
I don't know what the impact is of your genetics, but if I were you, I'd be fasting 3 days every month and take CoQ10, R-ALA, vitamin D3 & C and Lion's Mane Mushroom extract. Good luck to you.
@normastone1044 I take CoQ10 a lot plus D2, B7,B12, C. I also take Lion's Mane and moringa. I will be starting 24 and 48 hour fasting next month. I have bad fingers so disregard the thumb down. Thanks for the advice.
@@jeffsingleton7330
Recently, I badly injured my hamstring and developed complications, resulting in some nerve damage that affects walking normally. I started taking R-ALA and have been improving steadily over the last 5 weeks. Just something for you to consider.
@@jeffsingleton7330I would also be looking into taking phosphatidyl serine, manganese, copper, zinc, krill oil, cod liver oil, optimize vitamin D levels >50, ketogenic diet, thunder god vine, matcha tea for ECGC and l-thianine
@@normastone1044Does the fast need to be a water fast, or one where you can have teas and or black coffee? I’ve heard people say that if it isn’t a water fast, you don’t get all the benefits. I’m a 54 year old female and recently received a calcium score of 89 showing plaque in my arteries, as well as mitral valve regurgitation, tricuspid valve regurgitation and mild dilation (right side of heart). I’ve been put on a statin and told I need to take this as a preventative for the rest of my life.
you can't reverse atherosclerosis once it starts,
Yes you can.
The body isn’t stupid, something that’s not meant to be there will and can be removed by the system, but first the offending cause needs to be stopped. Once you find the cause and cease it, the body will do what it knows to do.
And yet here you are listening to how it’s done.
I fast every day! I usually eat 2 meals. My first one usually around 11 or 12. I do once an while a 24 hr. Anyway I had 2 A/fib and my last one my doctor told me I have 20% clogged arteries! I don’t drink or smoke!
What are the macros of those two meals? are you making sure you are getting enough nutrients, vitamins, and minerals in those meals?
Magnesium can help some people with Afib.
I don't think you're really getting into autophagy with that short of a fasting window.
I really don't think you getting into autophagy with that short of a fasting window.
Same here. Also, most Mondays go 30 hrs, and 3 times a year, I do a 72 hr fast.
Clinical trial on this?
• Autophagy is studied in lab animals. It's still a guessing game in humans. However, there are many " experts " who claim to know all . 🤔💭
why the annoying background 'music'?
Thank you Dr 👌
Wonderful production. I'm into this study
Thank you so much..
Has anyone figured out what to do practically to reverse arterial plaque with Autophagy?
Please answer me ♡ ♡ ♡.
Autophagy is triggered in the body during exercise and during fasting
Man you are smart. Thanks!
wheres part 2?
This is very interesting, the only problem is the music in the background is irritating.
Thank you very much for the very helpfull information
Dr Brewer: 0:02 0:02 request your advice on getting cimt either in Phoenix or Las Vegas. Self pay. Just need a phone number.
Great Info!! Thank you!
until ApoB goes to 130 by eating low carb/keto
Great, Video. Muslim are required to fast for 30 days each year during the month of Ramadan. It cleanses the body once a year from all the accumulated things that should not be there.
Don’t you guys only fast during the daylight? That it isn’t enough time for autophagy to start working. I do a 42hr fast once a week.
@@XingtheRubicon Muslim fasting from Sun up to sun down
Fast from sun up to sun down then feast like there’s no tomorrow during the dark hours.
Food taste so much better after a fast
The fast during day time only. But during night time they eat like …..
No hospital in the Philippines offers medically supervised prolonged water fast/autophagy. Please have an autophagy therapy and do it in one of our beaches in the Philippines
Do mean 'now'? Otherwise the meaning if your comments is reversed:)
Trust the Doc he always right
Bad advice
My LDL shoot up after a 72 hrs water fast
That's fine. Your body is doing what it needs.
Good stuff
Doctors in the Philippines dont want fasting autophagy as therapy for atherosclorosis and other chronic diseases.
Why?
Not in their guidelines
Ohh that means it's good to do. Guidelines against healing without buying drugs😂
Time and again have suggested a prolonged fasting with doctors as therapy.
Cannibolic is not a word
10 stories at a time, but none till the end. it's like my name is i am not going to detalize, I am from I am not going to go into this rabit hole, so now you know me well, let's whatch another video like this so you know more...
I don't think so. This kind would be quite expensive.
For now just a bunch of N=1's and "anecdotes"
Isn't that what the statins do. The body starts scavenging the cholesterol from the arteries.
K2 + nattokinase
K2 can remove the calcium
No idea who to trust lol
I feel you
Exactly🤔
So many conflicting you tube narratives.
I find it easier to trust those who have no financial stake in my health. If everyone was healthy, what would happen to drug companies and major medical institutions?
Your story Is very interesting! Could you please describe it in details so that we, people with some plague in arteries can apply it for ourselves. Thank you!
Be very sceptical of claims like these . He doesn’t back up any of this with any data or links to randomised clinical control trials .
Sorry Nick but following this advice and with subsequent lifestyle changes for over the past two years has resulted in not only health improvement but also the elimination of pharmaceutical drugs along with their subsequent side effects and further prescriptions to contend with those side effects. But each to their own.
@@uslanja For what reason did you need the pharmaceuticals?
What exactly allowed you to get off of the drugs? How did the intervention cure your ailments?
@@uslanja. Good for you. Am about to begin this protocol myself. Been an avid faster most my life, it really can cure if not at least accelerate healing.
❤John 3,16 ❤
What is up with the dark puffy circles under your eyes. This may be inflammation causing this
Isn't autophagy just Ketosis? All brought on by fasting...
Nobody as yet really understands exactly how autophagy works in humans. Most studies are done on laboratory animals. We know it happens, but the exact details are still a mystery . 🤔💭
Check out work by Dr Mindy Peltz
False!
welll….. AGAIN!…. a video of yours without CONCLUSION („what should i DO for more autophagy?“),…. so you avoid again any CLEAR advice….. (like always) …. sorry for maybe a little bit tough critique… 😢
We only get new body in heaven, put ur faith to Jesus Christ
And whole plant diet to sustain healthy arteries
That is the most bogus comment there is. Search humans were apex predators for two million years. Hypercarnivores. Consider this. Humans did not domesticate an animal that could pull a plow until 6,000 years ago. We never ate plants in abundance until extremely recently in our history and we don’t have the gut for it.
Pls don’t misleading Rapamycine very dangerously side effects