One Carbon Metabolism

In this video I have explained about one carbon metabolism reactions and the donors and formation of one carbon derivatives. Tetrahydrofolate (THF) plays a central role in one carbon metabolism. Vitamin B12, B6 and B2 that is cobalamin, pyridoxine and riboflavin, respectively, helps in the formation of one carbon derivatives from THF. One carbon metabolism participates in synthesis of thymidylate monophosphate, C2 and C8 of purine ring, synthesis of glycine from serine and conversion of homocystienine into methionine.
Link my video on folate trap is as below.
• Folate Trap
You Can Subscribe to my Channel for REGULAR UPDATES by clicking on SUBSCRIBE button above!
You can follow me on my BLOG by clicking the link below
drmungli.blogspot.com/
You can follow my Facebook page Biochemistry Made Easy by Dr Prakash Mungli, MD by clicking the link below. Here I post USMLE step-1 style MCQs and you can participate in discussion.
/ drmungli

[@navaneeth_us]

First of all I'll be honest out here. Before going through this video I was totally puzzled about the One carbon metabolism concept but post watching this video, every concept related to the same is completely demystified. This video is GOLD.
Thank you so much, Sir.

[@Rawteeth]

Thank you for the video and thank you for being detailed! It's 3 am here and I finally understand one carbon mechanism.

[@csatdsalem]

awesome video explaining the over arching concepts of one carbon metabolism. thank you very much for your organization of this concept!

[@DrMungli]

+csatdsalem Thank you. I'm glad you liked the video.

[@simplifymedicine2810]

Tqqqq sir
It was very helpful for me while presenting seminar....

[@dtanoli]

Dr. Prakash Mungli your biochem videos are awesome.Thanks

[@DrMungli]

100 lyric : thank you, I'm glad this video has helped you.

[@divya9549]

U explain everything so simply.. Thnku sir..

[@DrMungli]

You are most welcome. I'm sure now you have a fair idea about what is one carbon metabolism.

[@shaziasyed451]

nice video. looking forward for many other videos on various biochem topics.

[@DrMungli]

Thank you Shazia Syed, make sure to subscribe so that you get the notification.

[@vaishnaviramakrishna265]

Awesome Sir! Thank you very very much! You always are my biochemistry saviour!👍👏👏

[@viratveeru850]

excellent sir

[@alisaclark4560]

Very good. Thanks

[@a_peace_loving_man4953]

Thank you very much Sir for this really helpful video 🙂

[@emimaananth3886]

Hatsoff to u sir... really made well... thanku sir.

[@nishajha5903]

Thank you so much sir,🙏your explanation is very nice & it cleared my concept about one carbon metabolism 😁😁

[@Bettadenyou1]

very good. One correction, TS converts dUMP to dTMP. Thank-you for your videos.

[@DrMungli]

You are most welcome. Since deoxythymidine is only used in DNA synthesis hence its sugar has to be in deoxy form. This is why deoxythymidine is loosely termed as just thymidine and hence sometimes it is just written as TMP, TDP, TTP. Yes in perfect world it should be referred as deoxythymidine.

[@KRIPAJOSE-ne9qv]

Thank you sir🙂

[@nimrashafi7163]

Thank u so much sir

[@viratveeru850]

thanks sir very very very helpful me sir

[@DrMungli]

You are most welcome

[@adityakaul4441]

thank u sir. very helpful
sir can u plz tell
like u told folate def. may cause homocysteinemia.
Can cobalmine def. cause homocysteinemia?

[@DrMungli]

You are most welcome Aditya Kaul. Yes cobalamin deficiency will also cause homocysteinemia. This is by causing "folate trap" thereby decreasing the conversion of homocysteine into methionine leading to elevation of homocysteine in the blood. You can watch my "folate trap" video as in the link below.
Folate Trap
th-cam.com/video/xG52KGiRPFM/w-d-xo.html
In the below video I have explained all causes for homocysteinemia
th-cam.com/video/5of5jeOCFJc/w-d-xo.html

[@adityakaul4441]

thank u soo much sir.
U taught this concept so well.
it will be memorable now.

[@DrMungli]

You are most welcome.

[@prakashrane2289]

You are class apart

[@hemantjain8175]

sir please upload your another video on vit d your all video awensome

[@DrMungli]

Sure, please checkout my playlist.

[@sehajdeep9158]

👍