Powering the Cell: Mitochondria Animation

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  • เผยแพร่เมื่อ 3 ต.ค. 2010
  • xvivo.com/examples/powering-t...
    Together Harvard University and XVIVO developed this 3D animation journey for Harvard's undergraduate Molecular and Cellular Biology students about the microscopic world of mitochondria. The animation highlights the creation of Adenosine Triphosphate (ATP) -- mobile molecules which store chemical energy derived from the breakdown of carbon-based food. ATP molecules act as a kind of currency, imparting chemical energy to power all the functional components of cellular activity. This piece is the second in a series of award winning animations XVIVO is creating for Harvard's educational website BioVisions at Harvard. The first program, Inner Life of the Cell, received international acclaim and can be seen both on our website and the BioVisions site.
    www.xvivo.net
    multimedia.mcb.harvard.edu/
  • วิทยาศาสตร์และเทคโนโลยี

ความคิดเห็น • 776

  • @MikeGinnyMD
    @MikeGinnyMD 12 ปีที่แล้ว +80

    At age 17 in AP Bio class, my teacher described the workings of the mitochondrion in great detail. I was enthralled by the descriptions of carbohydrate metabolism, how energy was withdrawn from it, and how a proton gradient powered actual protein "turbines" that spun as they drove the ATP synthetases. The mitochondrion inspired me to pursue medicine as a career. This video is a wonderous piece of work, a combination of artistic talent and scientific accuracy. It's EXACTLY how I imagined it.

    • @cynthiaaaa5204
      @cynthiaaaa5204 2 ปีที่แล้ว +7

      Based upon your username, it looks like you've maintained that passion for medicine as a career. :) As a high school biology teacher, that makes me happy!

    • @fighter4049
      @fighter4049 ปีที่แล้ว

      @@cynthiaaaa5204 i am also giving mbbs entrance exam NEET in India on 7th may i studied alot from 3 years

    • @fighter4049
      @fighter4049 ปีที่แล้ว

      same my Biology professor teach this very deep with animations and slides in Cell the unit of life chapter

    • @Flowerthe9
      @Flowerthe9 4 หลายเดือนก่อน

      Yo, you are MD now man. Congrat

    • @alexrobson9038
      @alexrobson9038 4 หลายเดือนก่อน

      @@Flowerthe9big congrats to him

  • @doilfing
    @doilfing 8 ปีที่แล้ว +213

    The Mitochondria is the powerhouse of the cell.

    • @yayyo3226
      @yayyo3226 8 ปีที่แล้ว +5

      +Angelo Cantos FUNNY MEMES, XDDDDDD,

    • @jordanmcshan2196
      @jordanmcshan2196 8 ปีที่แล้ว +3

      they look like trains or worms

    • @sophiamore4631
      @sophiamore4631 4 ปีที่แล้ว

      Correct

    • @Hoo88846
      @Hoo88846 4 ปีที่แล้ว +5

      Mitochondrion is singular. Mitochondria is plural. The mitochondria ARE the powerhouses of the cell. It's where oxidative phosphorylation occurs generating more ATP (cellular currency) from glucose.

    • @ilsignoredellaluce2234
      @ilsignoredellaluce2234 หลายเดือนก่อน

      I love to see that it was a meme already 8 years ago lol

  • @bunnypro1224
    @bunnypro1224 7 ปีที่แล้ว +124

    WHY DOES THE MUSIC IN THESE VIDEOS ALWAYS HAVE TO BE SO EPIC?!?!

    • @car103d
      @car103d 6 ปีที่แล้ว

      Try dubbing these videos with ST motion picture (entering the cloud) or wrath of Khan (genesis project) soundtracks ;)

    • @NikoPapasideris
      @NikoPapasideris 6 ปีที่แล้ว

      haha I was thinking the same thing!!!

    • @davidfeng2641
      @davidfeng2641 4 ปีที่แล้ว +11

      Life is epic

    • @cuatropolis2881
      @cuatropolis2881 4 ปีที่แล้ว +1

      Because of the epicness

    • @sophiamore4631
      @sophiamore4631 4 ปีที่แล้ว +3

      Epic music discribe a journey, it is a journey, is it not ?

  • @hope4ul
    @hope4ul 11 ปีที่แล้ว +16

    If there were 3d animations like these for every subject in school I would just love to learn about them!

  • @DavidCameronFilms
    @DavidCameronFilms 10 ปีที่แล้ว +37

    This is pretty amazing all around. A little Morgan Freeman could make this Oscar worthy.

  • @TonyTigerTonyTiger
    @TonyTigerTonyTiger 12 ปีที่แล้ว +10

    @0:41 The bluish barrel-shaped molecule is a chaperone: chaperones help proteins folds into their correct 3-D conformation.
    @1:11 Together, each rotating “tree” and the stationary part right next to it that keeps the top of the “tree” from rotating is one ATP synthase molecule.
    @1:14 ADP (yellow-green) is binding to ATP synthase and then ATP (glowing) is being released.
    @1:28 ADP and ATP are being exchanged through the membrane.

  • @JeraWolfe
    @JeraWolfe 9 ปีที่แล้ว +18

    Found this gem during my studies into Mitochondria, ATP, and Glycolysis.
    Amazing sub-cellular eye candy.
    Mom's magical mitochondria.
    Enjoy!

  • @nwahs6022
    @nwahs6022 11 ปีที่แล้ว +16

    1:08 my favorite enzyme: ATPase!

  • @noahmasonscience369
    @noahmasonscience369 3 ปีที่แล้ว +12

    I absolutely love the mitochondria! Without my mitochondria, my cells would be unable to do cellular respiration nor would function properly. My cells biochemical functions wouldn't work properly either. Perhaps its best to have my mitochondria.

  • @kennethpgolden
    @kennethpgolden 13 ปีที่แล้ว +2

    a wondrous example of the complexities and phenomena of everything that is

  • @valerieflynn4225
    @valerieflynn4225 10 ปีที่แล้ว +6

    I'm doing a report on mitochondria, and I absolutely love this video! I'm gonna share this with all my science geek friends. Thanks!

  • @paulbriggs3072
    @paulbriggs3072 หลายเดือนก่อน

    It's a good thing no labels or descriptions of what was happening were added to this, because people might start figuring it out. Good job preventing that from happening!

  • @BigStickyNugs
    @BigStickyNugs 6 ปีที่แล้ว +1

    absolutely amazing. A mini factory working away 24/7 without us even noticing

  • @spicychickenwing31
    @spicychickenwing31 13 ปีที่แล้ว +2

    @CalyxAsgard It's the powerhouse component of the cell, which generates ATP (the fuel currency of the cell) responsible for catalyzing various biochemical reactions. It's also responsible for cell apoptosis, among other things.

  • @pepsico815
    @pepsico815 9 ปีที่แล้ว +20

    How fucking weird is this? When you think about it, it's like we're made up of some weird super advanced alien technology.

    • @oscarwang7365
      @oscarwang7365 9 ปีที่แล้ว +1

      Austin Texas That's actually very interesting!

    • @JamDaaMan
      @JamDaaMan 9 ปีที่แล้ว +2

      You think this is cool? Search for 'Motor Protein'.

    • @jamesotter7170
      @jamesotter7170 8 ปีที่แล้ว

      +Austin Texas u r dum and

    • @ereynatetasgrafas9933
      @ereynatetasgrafas9933 8 ปีที่แล้ว

      "Scientists who utterly reject evolution may be one of our fastestgrowing controversial minorities. Many of the scientists supporting this position hold impressive credentials in science."
      ~Larry Hatfield in Science Digest
      "I believe science is pointing strongly toward design. To me, as a scientist, the development of an embryo cries out, `Design!' The Cambrian explosion-the sudden appearance of complex life, with no evidence of ancestors-is more consistent with design than evolution. Homology, in my opinion, is more compatible with design. The origin of life certainly cries out for a designer. None of these things make as much sense from a Darwinian perspective as they do from a design perspective."
      ~John Corrigan "Jonathan" Wells (molecular biologist)

    • @pepsico815
      @pepsico815 8 ปีที่แล้ว

      +brotherbandit It could be intelligent design, but it's NOT some bullshit "God sent his son to perform miracles and die on the cross" fantasy story that we made up thousands of years ago.

  • @red.maned.unicorn
    @red.maned.unicorn 13 ปีที่แล้ว +8

    Unspeakably beautiful... any plans to add annotations identifying the key proteins, molecules, and ions to help us follow along? I know the basic sequence of events and I could recognize the obvious components (ATP synthase is pretty distinctive!) but it would be awesome to have a step-by-step guide to better appreciate this exquisite intracellular dance!

  • @buckslearningcooperative2082
    @buckslearningcooperative2082 6 ปีที่แล้ว +8

    This is so beautiful. I wish I knew more precisely what's happening throughout - a voiceover would be nice.

  • @yuriabreu337
    @yuriabreu337 8 ปีที่แล้ว +62

    I'm in tears. The human body is fascinating!!! Thanks to chemical evolution, coacervates, DNA, RNA etc. *---* We're all dust of the stars...

    • @frewerage
      @frewerage 8 ปีที่แล้ว +4

      +Yuri lol Have you ever read about the Cambrian Period ? Ironically, how you typed from a non living thing(star) come ... the living things (animal, human). If it is chemical evolution then I suppose pain and suffering are chemical imbalance too ...

    • @pirminhuller8490
      @pirminhuller8490 8 ปีที่แล้ว

      +Khanh Ly
      true that!! it is so fascinating and fancyy

    • @priyanshrawal2294
      @priyanshrawal2294 7 ปีที่แล้ว +1

      true just think about it we have trillions of nucleuses in our body

    • @frewerage
      @frewerage 7 ปีที่แล้ว +6

      ***** Please allow me to be blunt, evolution is a lie as well as 911, weapon of mass destruction, communists are evil, DDT & cigarettes are harmless.
      Have u ever heard of Congenital insensitivity to pain ? As the name implied, the person doesn't feel pain, also is a very dangerous condition. In this world we're known & living in, one may be able to take pain away ( only temporary if you have $ ). Some might even minimized suffering through pleasure ... but soon or later they will come back stronger, hence requires bigger "doses" or painkiller and pleasures. Mind you, only one person ever live can help a person who has bigger pain, his name is Jesus ( Yeshua )

    • @PaladinNL5
      @PaladinNL5 7 ปีที่แล้ว

      your profile picture is so aesthetic

  • @bruhmoment3697
    @bruhmoment3697 2 ปีที่แล้ว +1

    0:35 I was in bio class today and my teacher had this on when we were in passing period, and that part where you go in is so cool with the music, it becomes to happy then with the guitar as it looks at the atp synthase stuff

  • @rockyvai1767
    @rockyvai1767 5 ปีที่แล้ว +1

    WHY DOES THE MUSIC IN THESE VIDEOS ALWAYS HAVE TO BE SO EPIC?!?!
    21

  • @MIDNAq1LINK
    @MIDNAq1LINK 13 ปีที่แล้ว +5

    This is beautiful. Something so small does such a complicated work. I've just learned this in school (8th grade lol) and it's so fascinating. Some of the functions in our body are done on such a small scale it makes me wonder what a world exists below what our eyes can see.

  • @doughouge6780
    @doughouge6780 11 ปีที่แล้ว +1

    I am studying the effects of HIV and the drugs used to treat it on the mitochondria. Since the Dr.'s think I'm too stupid to understand it I will find out for myself and pass it on. This is the stuff that completely defies any explantion that we were created by chance.

  • @Starfish2483
    @Starfish2483 13 ปีที่แล้ว +1

    i love the ending part, it's so beautiful.

  • @christinastark-steffens1303
    @christinastark-steffens1303 9 ปีที่แล้ว +1

    Wunderschön...
    Sehr beeindruckend!

  • @Lanceleoghauni
    @Lanceleoghauni 13 ปีที่แล้ว +1

    This is so awesome when you know what's happening. Sometimes being a Biology major is just plain cool

  • @ramikafa
    @ramikafa 12 ปีที่แล้ว

    Just the phospholipid membrane looks gorgeous!!! Wonderful job!!!

  • @TonyTigerTonyTiger
    @TonyTigerTonyTiger 12 ปีที่แล้ว +2

    @0:16 The worm-looking thing is a mitochondrion (plural = mitochondria)
    @0:22 The strand is a protein and it has particles attached to it to keep it linear, so that it can fit through a protein channel in the membrane.
    @0:24 The particles are released from the protein as it feeds into and through the protein channel in the outer mitochondrial membrane.
    @0:26 The protein passes through the space between the outer and inner mitochondrial membranes and then through the inner membrane.

  • @northland-consulting
    @northland-consulting 13 ปีที่แล้ว

    animation, lighting, and rendering is of supreme quality and i enjoy watching this video.

  • @Rarae192
    @Rarae192 12 ปีที่แล้ว +5

    I'm choking up, this is so beautiful! It really brings to life what we've learnt in molecular biology. Trying to understanding the complexity of cellular biochemistry is something I'm confronted with on a daily basis, and every time I find myself saying, "This is fucking insane!"

  • @Kalkrot
    @Kalkrot 13 ปีที่แล้ว

    You/makers of this are...MAGICAL!

  • @annelucero7771
    @annelucero7771 4 ปีที่แล้ว

    Thank you, great job. Wonderful presentation.

  • @benh66
    @benh66 13 ปีที่แล้ว +1

    @AzraelUK1 That's an enzyme called ATP synthase. It's the very final step in converting sugars and fats into energy the body can use. It basically acts like a water wheel, using the energy of ions flowing through it to create an energy-rich substance called ATP.

  • @Mewi987
    @Mewi987 13 ปีที่แล้ว +3

    i wish they could of showed me this in school instead of reading 20pages about how mitochondria works..... DAMN YOU SCHOOL

  • @outkast334
    @outkast334 13 ปีที่แล้ว

    love it. makes anatomy n phisiology so much more entertaining

  • @quedulcefuetenerte
    @quedulcefuetenerte 11 ปีที่แล้ว +3

    Gracias a videos como estos es más fácil comprender estos procesos e ir más haya de las explicaciones orales. Muy bueno(:

  • @NancySuttonPierceRN
    @NancySuttonPierceRN 12 ปีที่แล้ว +1

    Watching this reminds me that we are magical beings. Beautifully done!

  • @Nick153452
    @Nick153452 12 ปีที่แล้ว +1

    @MikeGinnyMD That's really cool. I'm in college right now studying Chemistry and Biomedical Science. I was hoping to get into medical school, but I don't know if I'll get past the dreaded MCAT! Worst case scenario, I have interests everywhere so finding a graduate program I like shouldn't be a problem. Right now I am taking Organic Chemistry, physics and cellular and molecular biology and I couldn't love my classes more.

  • @jocelynsun8786
    @jocelynsun8786 7 ปีที่แล้ว +5

    This world is amazing~~

  • @gurprees
    @gurprees 13 ปีที่แล้ว

    absolutely brilliant!!!!! thumps up. shows how exciting the field of biochemistry is.

  • @lore3253
    @lore3253 3 ปีที่แล้ว +1

    Good video!! I've really enjoyed it

  • @jmusing
    @jmusing 13 ปีที่แล้ว

    wow this brings all those bio classes to another level...

  • @santrico
    @santrico 12 ปีที่แล้ว

    Wow! So good!! So good!! Cool video!!

  • @rudy10298
    @rudy10298 13 ปีที่แล้ว

    thus far best movie i've ever seen, great job!!!

  • @cassandrastevens7534
    @cassandrastevens7534 10 ปีที่แล้ว

    listened to this in school. LOVED IT!!!!

  • @sacr3
    @sacr3 10 ปีที่แล้ว +1

    Too much of this Universe I can't comprehend. The sheer size of the Universe, I can't. This 1 cell doing all this work, than knowing we have something like 7 billion or 7 trillion cells in our body all doing this busy work 24/7 for what?... Too much..

  • @augustooct8877
    @augustooct8877 4 ปีที่แล้ว

    Sencillamente IMPRESIONANTE ¡¡¡

  • @SabbyNeko
    @SabbyNeko 9 ปีที่แล้ว +94

    I want a Mario game set in this world.

    • @TheDunningKrugerEffectisReal
      @TheDunningKrugerEffectisReal 6 ปีที่แล้ว +1

      Sabbat-X you fight Virus Bowser at the end.

    • @friedchicken1
      @friedchicken1 5 ปีที่แล้ว +6

      Super Mario Cell?

    • @huyanhbui7105
      @huyanhbui7105 5 ปีที่แล้ว

      This was great, thanks, I have been researching "how to increase mitochondrial count" for a while now, and I think this has helped. Have you ever come across - Miyason Mitochondria Masker - (search on google ) ? Ive heard some pretty good things about it and my buddy got great results with it.

  • @heidinewton6303
    @heidinewton6303 3 ปีที่แล้ว

    This is so awesome!

  • @2000everett4
    @2000everett4 12 ปีที่แล้ว

    That was Brilliant.

  • @sleepcity
    @sleepcity 12 ปีที่แล้ว

    Best of luck to your in the rest of your education and career! We need more people like you in the US!

  • @WHITEHOUSE1600DC
    @WHITEHOUSE1600DC 13 ปีที่แล้ว

    wonderfully made

  • @organizersrus
    @organizersrus 6 ปีที่แล้ว +1

    Would be great for someone to do a voice over to explain what it is that we are seeing. Thanks

  • @LilBeezy1992
    @LilBeezy1992 13 ปีที่แล้ว

    THIS BLEW MY MIND

  • @ChaojianZhang
    @ChaojianZhang 3 ปีที่แล้ว +1

    Damn this is beautiful.

  • @daywalkerin
    @daywalkerin 13 ปีที่แล้ว

    Wonderful... nature is so beautiful!

  • @kotosqoposrly
    @kotosqoposrly 5 ปีที่แล้ว

    This is SSSSSOOO cool!!

  • @sweetiepienumber1
    @sweetiepienumber1 9 ปีที่แล้ว +1

    Thank you for the efforts and for sharing this helpful information :)))

  • @MrFrank1393
    @MrFrank1393 10 ปีที่แล้ว

    This is fantastic!

  • @louispearce3499
    @louispearce3499 11 ปีที่แล้ว

    Cool video. it looks so real.

  • @Lekozza
    @Lekozza 13 ปีที่แล้ว

    The Wonders of Creation Reveal Gods Glory!

  • @pebre79
    @pebre79 13 ปีที่แล้ว +1

    Amazing video! It would be nice to have some narration though. Keep up the great work!

  • @hellonancy16
    @hellonancy16 13 ปีที่แล้ว

    WOWWWW... that was amazing.

  • @sterlwh
    @sterlwh 11 ปีที่แล้ว

    Beautiful video! How close to reality are the textures and movements of the video to what we understand them to be in real life?

  • @000Bacteria
    @000Bacteria 13 ปีที่แล้ว +2

    woow !!

  • @KnightOnlineAshet
    @KnightOnlineAshet 13 ปีที่แล้ว

    Seeing bioscience through understanding become engineering. Gives us hope. I just love the molecules as machines graphics. It would be nice to see the energy enriching process with annotation or commentary. Not just glowly graphic.

  • @shubhangipatil1489
    @shubhangipatil1489 ปีที่แล้ว +1

    Thanks for explanation

  • @somersault1824
    @somersault1824 12 ปีที่แล้ว

    truly amazing!

  • @michaelzavala9229
    @michaelzavala9229 11 ปีที่แล้ว

    Amazing. Thank you!

  • @sunildadhich1236
    @sunildadhich1236 4 ปีที่แล้ว

    Superb

  • @levuthuan
    @levuthuan 13 ปีที่แล้ว

    wow, amazing! I love it

  • @josescott8673
    @josescott8673 11 ปีที่แล้ว

    Amazing animation.

  • @vithalbhaipatel1013
    @vithalbhaipatel1013 2 ปีที่แล้ว

    Well show. Good information.

  • @N30designs
    @N30designs 13 ปีที่แล้ว

    awsome video it's very beautiful. This is very graphical for understand the biology of the cell. Very great job.

  • @Raulwithaccent
    @Raulwithaccent 8 ปีที่แล้ว +3

    There's a mistake. The c-ring should be rotating clockwise (looking it from the cytosol) while synthesizing ATP.

    • @friedchicken1
      @friedchicken1 5 ปีที่แล้ว

      no, that's a cell from a left-handed person

  • @Rhayssaandrade_
    @Rhayssaandrade_ ปีที่แล้ว

    que perfeição !!!

  • @StringsCrusader
    @StringsCrusader 13 ปีที่แล้ว +1

    It looks like a machine. A bit freaky actually. But also extremely beautiful at the same time.

  • @eddieogorman70
    @eddieogorman70 12 ปีที่แล้ว

    Beautiful

  • @rockcityfilms
    @rockcityfilms 13 ปีที่แล้ว

    I would enjoy seeing a narrated version of this. As wallpaper it's very compelling, but it would be nice to understand what we're seeing.

  • @Manajust4fun
    @Manajust4fun 12 ปีที่แล้ว +1

    amazing video I love biology

  • @SuperAsianSalsero
    @SuperAsianSalsero 13 ปีที่แล้ว

    WOW! I freaking love it.

  • @hassan713380
    @hassan713380 12 ปีที่แล้ว

    just awesome !

  • @peacefreak99
    @peacefreak99 7 ปีที่แล้ว +1

    Is there a narrated and annotated version of this video? I'm not asking for David Attenborough (but if he's into it...)

  • @FutureAIDev2015
    @FutureAIDev2015 8 ปีที่แล้ว +4

    That mitochondrion reminded me of a CCS-class Covenant battlecruiser from Halo 1...

  • @duraik3594
    @duraik3594 6 ปีที่แล้ว +1

    Visual with Music makes us interested in science

  • @Egyptiangurl111
    @Egyptiangurl111 12 ปีที่แล้ว

    The glowing particles are ATP and the turning protein cranking them out is ATP synthase. The particles turn from a green color (ADP) to a glowing color (ATP) with the addition of an inorganic phosphate.

  • @BaptisteJacquet
    @BaptisteJacquet 11 ปีที่แล้ว

    How can we not like it? It's my favorite too!

  • @Yongsan12
    @Yongsan12 13 ปีที่แล้ว +1

    Wonderfull! This is the art of the nature! Who can imagine the hard and incredible proceess that Mithocondria's do?
    Sorry bad english XD

  • @duanvan8425
    @duanvan8425 4 ปีที่แล้ว

    The body is indeed a marvelous micro apparatus

  • @black11foot
    @black11foot 13 ปีที่แล้ว

    That is pretty sweet graphics, i wonder what type of software they used to make it?

  • @Jannik3366
    @Jannik3366 13 ปีที่แล้ว

    a real beauty !

  • @theflexintexan2152
    @theflexintexan2152 10 ปีที่แล้ว

    What effect does exercise have on your mitochondria count per cell?

  • @sarasalano3781
    @sarasalano3781 11 ปีที่แล้ว

    Informative, thank you.

  • @setsaaa
    @setsaaa 11 ปีที่แล้ว

    awesome...

  • @sclogse1
    @sclogse1 13 ปีที่แล้ว

    Note the Supported by the Howard Hughes institute at the end...these guys don't depend on government whims...the on and off faucets of conservative government (stem cell research etc.) So, they deserve our highest rating...and deepest bows.

  • @12ock
    @12ock 13 ปีที่แล้ว

    its amazing that every part of protein can helps the cell to live.....and to form to a greater structure.... and into an social organism

  • @justsomegirlwithamustache
    @justsomegirlwithamustache ปีที่แล้ว

    I'm taking biology in college and was about to cry because nothing I was reading made sense! After seeing this and other videos showing what's happening in 3D, I think I'm starting to finally get somewhere 😭

  • @JIMvc2
    @JIMvc2 12 ปีที่แล้ว

    This looks soo Beautiful :) of how ATP goes to ADP :D and Electrons,Ions,ect...

  • @ArunieShyama
    @ArunieShyama 10 ปีที่แล้ว

    great video!

  • @JojiBronner
    @JojiBronner 13 ปีที่แล้ว

    beautiful!

  • @Bl4Xtorm
    @Bl4Xtorm 13 ปีที่แล้ว

    thats amazing