ฝัง
- เผยแพร่เมื่อ 17 พ.ค. 2024
- Mitochondria are so much more than the powerhouse of the cell. In this episode, Patrick explores why this organelle is so unique and introduces new research that you probably didn’t hear about in school.
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“The mitochondria is the powerhouse of the cell,” has got to be the most repeated line in biology. It has been firmly inserted into our middle school textbooks for years, and the powerhouse nickname stems from the mitochondria’s energy production capabilities, but the mitochondria offers so much more than that.
To start, when discussing all the mitochondria in our bodies, we use mitochondrion for singular, mitochondria for plural.
Each Mitochondrion looks different from cell to cell, and there are hundreds of thousands of mitochondria floating around in your cells-though that number also depends on what tissue we are referring to.
But, regardless of shape and number, all mitochondria do have some structural things in common: They each have two membranes-one outer layer, one inner layer, and some space in between them.
While the outer membrane works like a protective but permeable layer, letting different compounds in or out of the mitochondrion, the inner membrane is where some important biology happens to manufacture ATP (or Adenosine triphosphate, an organic compound that provides energy to drive processes in living cells).
So how did we develop mitochondria and what are all the things they do for our bodies?
Find out more about endosymbiosis theory and all the different roles your mitochondria play in this Human.
#mitochondria #cells #humanbody #health #biology #seeker #science #human
Read More:
Why do our cell's power plants have their own DNA?
www.sciencemag.org/news/2016/...
“It’s one of the big mysteries of cell biology. Why do mitochondria-the oval-shaped structures that power our cells-have their own DNA, and why have they kept it when the cell itself has plenty of its own genetic material? A new study may have found an answer.”
Cells Living in Cells
askabiologist.asu.edu/explore...
“It’s good to be friendly with your neighbors, right? Individuals and communities do better if they help each other out. Cooperation isn’t just important for humans; without a bit of interaction with neighbors, life as we know it would not exist.”
mtDNA and Mitochondrial Diseases
www.nature.com/scitable/topic...
“Did you know that you have a second genome? Small cellular organelles called mitochondria contain their own circular DNA. What happens to your cells when this DNA mutates?”
____________________
This Seeker health miniseries will dive deep into the cellular structures, human systems, and overall anatomy that work together to keep our bodies going. Using the visual structure and quick pacing of Seeker’s Sick series, these human bio-focused episodes will give a new audience an inside look on what’s happening inside all of us.
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Me : Sees Video Title
Also me:
*years of academy training wasted*
ARMY?????????????
@@zack7122 hehe hi
@Christopher Damant it's a profile pic only some could get ;)
Excuj meee that your fault
@ r/woooosh
The mitochondria is the powerhouse of the cell!
Bah
The mitochondria is the powerhouse of the cell!
⭐
Are the power house of the cell
“Hahahahaha “ in Russian accent
I'm a biomedical researcher just working with a mitochondrial protein called IDH. IDH is involved is normally involved in the citric acid cycle (the pathway which eventually drives the production of ATP in mitochondria) but specific mutations inIDH are also frequently found in different cancer types. The reason is that mutated IDH can lead to the production of a harmful molecule which messes up a lot of proteins leading to the repression of genes which would normally protect against the development of cancer (I would love to make a video about that mechanism one day). After so many years of research, mitochondria still show fascinating new sites!
just to save someone a google search, IDH = Isocitrate dehydrogenase. Also, looking out for your video!
Thanks a lot for the info 👏. Waiting for the video!
awesome,, looking forward that video
Chinese Virus not very much unless you’re hired by a super rich private company like oscorp in spiderman. A lot of time is spent asking for money for their research so they can continue their stuff and also live and lots have another job like working at a university.
Hey! Long time no see. Fellow researcher here stalking the same corners of the web. Another thing I've been shocked about for a while since I began doing research with mitochondria is that the textbooks never accurately describe their structure. They form long networks in some cells that are constantly fissing and fusing. I never knew they formed such networks existed or that fissing and fusing was so important (especially to cancer) until I began looking into its mechanics.
The cell is the power mitochondria of the house!
The house is the power cell of the mitochondria!
Power is the cell of the mitochondria house!
house of mitochondria is the cell power!
Mitochondria house is the power of cell!
I think that will be it guys 😂
*Title* : Mitochondria is not just the powerhouse of the cell
*Me and the boys* : Those Bastards Lied to us
For years.
Time to riot
Revenge time!
Lolz
Heart: *laughs in mitochondrial superiority*
Cam plays - You’re so funny.
Lol
So the heart muscle cell has an average of 35 to 40% mitochondria per volume? That's amazing. It makes sense since it's still very active even when we sleep.
And because the heart only runs the CAC
Ok I m also going to comment every video I see
Just like our D!CK....
Once your muscles hit 100% mitochondria per volume, you have officially transcended.
I swear I saw u in boy in bands video abt school
*pausing the video* Before watching the video I just wanna say one little thing... The cell is the power mitochondria of the house. That's it! Thank you! Let's continue watching. *resuming*
The real question is: What is the powerhouse of the mitrocondrion??🤔
thermodynamics
@@bradug Oh yeah. it has something to do with kinetic energy right??
quantum fusion charge
lol
he actually said it in the video. tacos. tacos are the powerhouse of everything
Everyone: The mitochondria is the powerhouse of the cell
Me: come on guys, really?
Also Me: The mitochondria is the powerhouse of the cell
Also Everyone: come on dude, really?
Fundemort Grey Prime Defender of Truth and Justice Also Me: Yes really
what powered the cell before symbiosis?
Mine liege I would like to inform thee with great haste that thee mitochondrion produces significant energy to power thee cellular structure
So Obiwan was talking about this and the force!
thy* mitochondrion/cellular structure
"Thou" is the subject form, "thee" is the object form, and "thy" is the possessive adjective (and "thine" is the possessive pronoun, like "yours" or "ours")
That's just a fancy bulshit away to tell me mitochondria is the powerhouse of the cell just speak to me like a normal person instead of a fancy wanker and tell me mitochondria is the powerhouse of the cell
Surely you jest!
3.53 "Endosymbiosis theory suggests that eventually, one of those anaerobic single celled organisms consumed an aerobic purple Bacteria that survived being eaten and they kicked off a symbiotic relationship. That was the first mitochondria. That purple Bacteria could consume and metabolize oxygen, which provided energy for the host cell. And in return, the host cell protected the bacteria."
Could someone please explain : ATP is a necessity for all life. So since an anaerobic cell had no source of energy before endosymbiosis, how did it survive and function until then?
I’m no expert but would it have anything to do with viruses being the first parasites on this planet and bacteria as its host?
Nobody :
Schools: Hey did you know that *Mitochondria is the power house of cell.*
I think "Everybody:" is what is meant.
Me: Hey did you know that chloroplast is the power *plant* of plant cell?
Seeker: ...
@@louf7178
XDDD
Star is the powerhouse of the solar system.
Big if true
(It's true)
Which star? Or you mean Star from Cartoon Network?
@@Altraiid No he/she mean't the star from the more you know
This was a fun episode to write, hope you guys like it ☺️
Editing this was fun too 😁
Please remove the distracting music
There's an update available which you probably can't edit into the video, about which parent we inherit mitochondrial DNA from.
This is the most important video on health
As a person with mitochondrial diseasr I'd like to say thank you for creating this video. It is one of the best I've seen on the topic.
@@viracocha Huh?
@@viracocha he just said he had mitochondria disease
Hi, how are you now? I'm being currently tested. Any advice?
@@Alexe829 As it's a degenerative condition I knew my health would deteriorate but in my case thats been reasonably slow and consistant. Unfortunately I got glandular fever and ended up with post viral Chronic Fatigue Syndrome, fibromyalgia, POTS, Mast cell ectivation syndrome etc which often seem to accompany each other. In spite of all that I've learned that it is possible to maintain a certain level of wellness, have a reasonable quality of life, and also contribute to society in a meaningful way.
I don't generally give advice except that which I found most helpful at the beginning of my journey.
1. Listen to your body. Every peraons journey and symptoms can be quite different.
2. Join a supportive community. As there is no cure and treatment options are limited finding a helpful supportive community is essential as they can share tips and tricks for staying as healthy as possible and offer support when things get difficult.
3. Start low, go slow. If you ever try something recommended by others start very slowly and on low dose/setting as your body may not respond in the way you might expect.
3. Be honest about your symptoms, even the weird ones. Mitochondrial issues can cause all sorts of bizarre sensations and dysfunction. 4. Find a dr you trust not to make you feel stupid for bringing up things that might not make sense at the time, or that blames everything on your mental health. Though mental health issues should be addressed, gasslighting patients is unprofessional, appropriate and uncalled for. If a dr does that to you, don't waste your time with them.
5. If you don't end up being diagnosed with a mitochondrial disorder font give up searching for a diagnosis. Just because the nedical fraternity spent know what is causing your symptoms, doesn't mean that it's nothing. Don't give up, don't give in, you deserve a diagnosis however long that takes.
I hope all is going well and that you find peace and confort in your life whatever form that takes.
@@gmdrandom6287 I figured that if Viracocha actually knew me they'd know I wasnt lying. Trolls are gunna troll so I thought ignoring them was probably best. Thank you for your comnent though. :)
These Human versions of Seeker are truly awesome. I really enjoy them. Teaches me SOOoo much!!! Way to go. But dont stop the other regular Seeker videos. Luv watching all of them
the mitochondria is the power house of the cell !
NOTINMYARSE ! ThE mItOcHoNdRiA *aRe* ThE pOwErHoUsE oF tHe CeLl !
@@Spacedog_42 ahhhhhhhhhh
@@arnjain same name bro.
Cool ! My college days ended in the late 90's. My favorite classes were A&P lecture and mostly lab. The cell structure, constituents, and function was my favorite point of study, primarily the Mitochondria. I was fascinated by this micro powerhouse. It seemed so surreal. I was wondering what new developments would arise in the future after further research was performed on this particular particle of wonder. So, once again... Cool ! I look forward to learning more about this subject matter.
Thumbnail - The most badass - High-tech - futuristic Mitochondria.
Video - 6th grade drawing.🙂
Great knowledge though 🔥🔥🔥
*THE MITOCHODRIA IS THE POWER HOUSE OF THE CELL*
SCP 89 THE MITOCHONDRIA IS THE POWERHOUSE OF THE CELL
are*; 'mitochondria' is plural
(yes I watched the start of the video)
Ah! There you are!
the mitochondria is the powerhouse of the cell
Mitochondria is plural,hence,are should be used.
Apart from the meme,i did learn something NEW
MITOCHONDRIA is also the POWERHOUSE of our ANCESTORS.
Yeah
I wonder if "The mitochondria is the powerhouse of the cell" will become an eternal meme that is passed down in our culture for as long as children are taught biology.
Thank you for making this video. The pace, depth, and visuals are perfect for my students. You will be added to my lessons 😊
The mitochondria is the powerhouse of the cell
Not often that a video goes "but you may ask..." with what I was actually asking. So glad I don't have to sacrifice any sleep time to solve unanswered questions! Loving this series.
Last time I was this early, the mitochondria was still the powerhouse of a cell.
Would love more about how Sirtuins and NAD play a role in the mechanism. As you know NAD boosters NR and NMN are a big part of the anti-aging right now (will look forward to the ATP video).
Outstanding - thank you !!
This is the "Mitochondria is the powerhouse of the cell." comment youre looking for.
Thank you for never disappointing brother! 💪🏿
Patrick is doing a great job on seeker, i like very much his medical related videos
He has his own channel. Called Corporis if you don’t know and really enjoy videos by him.
Thank you so much
You've answered all my questions
Awesome summary!
8:56 "making the mitochondria a warning signal that something bad is happening" .... which fits with the CENTRAL role of mitochondria in apoptosis (programmed cell death).
Midichlorians are the powerhouse of the force.
Hmm, that's interesting! Can't wait to learn more!
Mitochondria are awesome organelles!
I have been following you since the very beginning and have seen you grow. Your work and dedication has inspired me to start my own channel and put in a lot of effort
Looking forward to your support and advice as always!
Aaaah. Mitochondria. The powerhouse of the cell.
The force? Obiwan was speaking the truth!
Thanks. Very imformative
Such a great knowledge I learnt. It's help alot for me as a beauty consultant.
Whenever I see Mitochondria I always think of the Parasite Eve game and it makes me miss it.
Great game, that one. Makes me wish i had mitochondrial powers too
If you want to learn theories on how mitochondira evolved, Nick Lane wrote a book called "Vital question" goes in depth about endosymbiosis and
Chemiosmotic coupling.
We believe in the Almighty
Great, PERFECT, everything I knew from school gone now thank you
My mitochondria are off the charts. Over twenty thousand!
Mitochondria to each other: Remember guys, the cell is the powerhouse of the world domination.
"Has been firmly inserted into our Middle school textbooks for years"
High School Biology : Am I a Joke to you?
i really adore this series. you're doing a great job Patrick
Your Diet, Lifestyle Is Some Of The Most Important
Thanks doc for this interesting and simplified video yet informative indeed
my god, the hosts of this channel are just perfection in the way they narrate everything, How do they do it?
To accept the endosymbiotic hypothesis is a huge step of faith.
Endosymbiotic theory*
@@abel3557 It doesn't fit the criteria of a theory.
@@doctortabby It in all ways does. Present your peer reviewed study to back your argument.
@@abel3557 The burden of proof is on those who would try to assert such an absurdity. The need to present peer reviewed material to discredit this nonsensical notion equates to the need to present peer reviewed material as to why 2+2 doesn't equal 5.
It may be helpful to look at what a theory actually is.
Very interesting and informative 👍 thank you
I learn so much from these videos. I wish they would have taught like this is my High School.
They won't
School forever gonna be the same and boring machinic place
ThE POweR HouSe oF THe CELL
Thanks seeker!
2 1/2 years later....still the powerhouse of the cell!
Teachers: wait that’s illegal
The Mitochondria is the powerhouse of the cell.
U did not add the exclamation mark (!) as shown in the video.
At the end.
!
😒😒
❤excellent explanation 👌
Fascinating great information! So interesting! BTW, how did the information in the mitochondria get into our common African ancestor? Eve of Adam?
Mitochondria are the powerhouse of the cell
Millions of years ago, a mitochondrion walked into a bacteria and BAM! Science.
My only power move in the intellectual community rendered useless.
Thanks for spoiling my quarantine SEEKER.
RARE interesting Seeker video. Ilike it DRY ;)
I sometimes forget that we all have symbionts inside of us... Like Venom >:3
What even is a powerhouse anymore. We just call them power plants now.
Awesome. This information should open research on how fasting should allow cells to “clean themselves” during the fasting stage
Very nice😊
Sir, you said in matrix most of the ATP generated but other ATP generates where please tell
Nice video. Great presenter!
Can you provide a link of fossil records or confirmation of a mitochondria that is not within a cell?
WHO ELSE VOTED FOR HEART CELL!?
BIO CHADS RISE UP
I feel it's the most obvious choice. The heart _needs_ energy or else everything dies.
I'd have replaced liver cell with neuron, since the brain is known to take up about 1/4 of your total energy needs. When I think of energy-intensive organs, the liver wouldn't be in the top 5 for me.
Adenosine Triphosphate FTW! Thanks powerhouse of the cell!
The shape can vary but usually implies a pathogenic state
And the Worker is the powerhouse of the Economy.
*USSR National Anthem begins*
This is the third comment, "mitochondria is the powerhouse of the cell."
U did not add "The" at the start and exclamation mark(!) at the end as shown in the video.
@@greenrace8854 hahaha you got me!
😁😁
So much termins used in here - I will go to bed confused again except for remembering that "Mitochondria is the Powerhouse of the Cell"!
Mitochondria to Nucleus:
We're the power cells of this house!
When I read this I thought it said midichlorian at first
Maybe George Lucas is trying to tell us something....
Mitochondria's relationship to cancer is far stronger than you indicate. Please expand with a video on the Warburg Effect - a very recent area of research focus and something most people with cancer can take advantage of themselves to greatly increase the effectiveness of standard therapy.
DCA
Me: seeing this 3 years ago when i was a grade 6 student
Also me: i have forbidden knowledge.
I thought i was so smart knowing this. And then find others know it too.
mitochondria are the pets to our cells. (imagine if one day if the mitochondria decided to rebel and kill us all)
I've seen a pitbull attacked its owners 😓
Maybe the real powerhouse of the cell is the friends we made along the way.
You have a new subscriber!
I'd always thought each cell had one mitochondrion 😳
Chondroma is the name given for all of the mitochondria within one cell.
I was introduced to mitochondria when I first played Parasite Eve. Fascinating. Thanks for the video!
Melchizedek Phuah Siow Jin that’s such a cool video game. Still remember it’s gameplay and it’s story theme.
@@liggerstuxin1 Right? I love the music too! The atmosphere created was intriguing.
awesome informative stem video > keep them coming!
Great video! Filled in a lot of knowledge gaps for me.
Mitochondria also sets people on fire in Parasite Eve.
Thanks 90s Squaresoft games!
Look up parental mitochondrial DNA inheritance. I remember seeing developments that might put in question the maternal inheritance theory.
That’s what I was wondering. I had thought it was passed to girls only & they carried the paternal line
Not just a genomic Eve we also have genomic Adam. Look it up.
my teacher described mitochondria like a cellular power plant
the mitochondrion is also responsible for weight loss as it's the only organelle that can burn fatty acids in the cell and tha allows us to use the energy stored in our body fat
Just a clarification: not only do mitochondria have a 'lipid bi-layer' as a semi-permeable membrane but ALL cells have that. And this should hint at the 'origins' of the mitochondial [cell]
I always preferred to think of mitochondria as the 'Heath Bar' of the cell.
Seeker teaches me more than in school. My school only taught me that Mitochondria is powerhouse of school. This is blown up my mind 😳