I learned how decades of making a vaccine was done in less than a year. It is amazing to see how instead of injecting the body with dead or less strong viruses they can inject the body with MRNA which gives our cells the instructions to make defense against the virus.
You've got it Muhammed! Very cool stuff. A lot of the early work on mRNA vaccines had been going for years. It was mostly for Ebola and other deadly viruses. But when Covid came along, the scientists could easily pivot and align the technology platform against this new threat. Thanks for watching.
@@Sara-gl8ue Now, I am hearing of people suddenly dying in their sleep from heart attacks. We are burying my 51 year old female cousin this Monday from that. And today I just heard of a 37 year old mother of an 11 year old who also suddenly died of a heart attack in her sleep. She was a nurse’s aid in a nursing home. All these sudden and excess deaths due to heart attacks and other reasons. So, once again…NO, THANK YOU!
@@lookingup9041 I'm so sorry for your loss. I currently have a cousin in the hospital because of a brain aneurysm. She's young and healthy but she did get vaxxed because of her job. A friend of mine just posted about her friend dying suddenly and unexpectedly in her sleep. She was in her early 40s and was a nurse, so I can only assume she was vaxxed. Something isn't right.....
And now, according to Japanese research, lipid nanoparticles are found in large quantities in bone marrow and ovaries. Which means the mRna is migrating to other parts of the body and no one knows the long term effects.
I have a few questions that seems to be excluded from all mRNA explanation. What happen to the cell that have made the spikes now that the killer cells have identified them as a virus? Are they killed in the process? Do we kill our own cells in order to create the spikes? Is it correct that the mRNA doesn't only affect cells at the injection site, but also travels throughout the body? Does the mRNA particles travel across the brain/blood barrier in humans like it does with mice? What other vital organs does the mRNA reach?
technically, it was suppose to dissolve on it's own, like normal mRNA. And as another security measure, cells generally die over time. This is according to Dr. Been. But I think he might be wrong, as new studies from Germany in July came out suggesting they stay in the cells for over 2mths if not longer, and they do migrate. So...Just go out and enjoy your love ones, and pray that this is all an nothing burger.
Conventional vaccines introduce a virus protein or attenuated virus. The mRNA vaccines are innovative because they do not introduce a protein or whole virus. Instead, they contain mRNA which codes for a virus protein. Then it is up to the patient to translate the mRNA into protein. In that way, the body is making its own vaccine; i.e. the spike protein which will trigger the immune response.
Uh... yeah... and natural immunity will "remember" the entire molecule to neutralize at all possible sites not just the spike protein. A vaccine based on the spike protein will have unknown ability to handle variants with a different spike and of course, that is exactly how the variants differ; a different spike protein. Natural immunity would recognize all of rhe neutralizing sites so common sites (other than the spike) for the variants are still available. Natural immunity might handle the variants .. while the vaccines will require a new jab for every spike protein variant (vaccine merry-go-round .. not a fun ride). Natural immunity is way better yet the "narrative" suggests that the vaccine is recommended even for people who got C19. This .. is a ridiculous suggestion since the vaccine "response" will likely overshadow the natural immunity response .... meaning only that only spike protein antibodies might be produced which might not even work. The "other" neutralizing sites might not be targeted after vaccination which reduces the effectiveness of natural immunity. Idiotic .. yet universally suggested.
Ohhhhh maaaaan.... Another one eh? Make sure your tinfoil-hat is on nice and straight so that when the government tries to beam into your brain it's deflected 😑 there is no Nano microprocessors or technology being injected into you. Why do you people keep breeding?
Covid Event 201 is a biosecurity psyop to usher in Agenda 21 de-industrialization aka The Great Reset. See all-cause mortality in your country and compare 2019 to 2020.
@@jesuschristislord77733 Event 201, released a mere few month before the plandemic. It's just a perfect coincidence, the likes of which a mathematician couldn't calculate. Take that gene therapy anyway and dont' think about it.
@@saintejeannedarc9460 The WHO called covid a pandemic 666 days after the Clade X pandemic scenario. The first case in Wuhan on 1st December 2019 was 66 years 6 months after the CORONAtion of Queen Elizabeth II. In the UK we are now in a lockdown which started on 5th of January 2021. That date fell 66,666 days after Queen Victoria was CORONAted. Our great leader is now saying that lockdown will be eased on 8th of March 2021 meaning the final day is the 7th of March which is the 66th day of the year and coincides with the 7th also being a time span of 66 weeks since first case in Wuhan. The 666th day of Corona will be on 27th of September and will be 116660 days since the coronation of Queen Anne who was born in 1665 the year of the plague just before the Great fire in 1666.....666 rituals
@@Scribe3168 That's all pretty interesting, but it's not going to convince the science crew in here. Thankfully, what is giving them pause is the dodgy and experimental gene therapy nature,and how irresponsibly rushed they are.
They forgot to show us how they are delivering that messenger RNA package right into your cells. In the case of the DNA viral vector vaccines, coming out soon, they send their genetic instructions right into your nucleus, where your DNA is. Or that this technology is called gene therapy. Of course the fact checkers are hard at work lying about the gene therapy aspect of the vaxes, but I've seen enough science articles bragging about straight from the title.
I tell you what can possibly go wrong: This mARN vaccine wich is technically a virus since it contains genetic material that infects the cell and hijacks the cell protein synthesis system can cause cancer. A cell that produces foreign proteins can be considered as cancerous cell by the immune system and treated as so. Many forms of cancer are induced by viral infections at first. See HPV virus. Also many plants develop cancer after being injected with various plant viruses.
@@nopretribrapture2318 There is no actual hydrogel in the mRNA vaccines. They encapsulate the cell hijacking messages in a lipid nanoparticle shell. Luciferase is generally used for testing. They are gene editing though.
A few issues here... lipid nanoparticles used are mixed with polyethylene glycol and remain on the cell walls (possibly forever), and future viruses can easily invade the cell without entering through the ace2. The inserted mRNA creates the same spike proteins that exist on the sars cov 2 virus, but those spike proteins contain prion-like structures that can break through the BBB and drastically raise the chances of neurological diseases like Alzheimer’s and Parkinson’s. Plus, the antibodies that attack the spike proteins are reprogrammed to become overactive and overwhelm other normal antibodies which are wired to fight other common colds/viruses. It appears that the effects of sars cov 2 might be amplified with receiving the mRNA vaccine.
scientists, doctors and bioengineers are human too and they make mistakes sometimes. Did you know that a quarter of a million people die each year due to medical errors?@@112rorz
Yep. Human 2.0 is supposedly what they're calling GMO Humans. Almost like an update... This is all so weird, and crazy. The people working on this stuff are connected to some shady sounding projects and foundations, DARPA, Rockefellers, Common Health Pass, Gates Foundation, Agenda 2030 which is the Sustainable Development plan and is being pushed as a "climate crisis" and will by law get people in trouble for using things from nature, synthetic meat, eating insect proteins, living in Smart Cities, and according to sources, the "0 net emission goal" and "fixing poverty goal" may or may not require the culling of the population, meaning they'll kill people to get it done, and replace the reduction with AI, robots, which is exactly the kind of thing that companies like DARPA, Boston Dynamics and others are working on as we speak. This may mean the end of us and the beginning of a synthetic hybrid race, this being Human 2.0.
@@EK-sx9ek Giants, Nephilim that had to be wiped out by the flood.... I remember reading a book about a connection between the Nephilim and aliens, ETs, it was interesting. But yeah, it sounds like they want to make a human hybrid. Human GMOs soon to walk among us? But don't GMOs suffer a degradation and drop in quality? Maybe the modified humans will be sterile, unable to have children, and be under malevolent influence.
@@CoolDrifty Oh believe me... When things really go out of control for real... Because lemme tell you something... This COVID is just the calm before the actual storm... And when things actually go awry.. in ways we couldn't even begin to imagine... men's hearts will fail them for fear... 2020 was NOTHING... compared to what is coming... I just hope we are able to survive. And I pray to God the needle isn't part of the agenda... I just have this awful feeling in my spirit.. Stay safe, and stay blessed.
Lucifer means light-bearing in Latin. Lux- light and ferre- bring or carry. They named it luciferase because it was discovered in glowing creatures in nature. The protein that was discovered also allowed scientists to have things glow when we shine a light at it under a microscope making it easy to study very small things and where they are going in and on a cell.
Intresting and disturbing, but what i would like to understand is once there nanoparticles done its job according to this video where do they go and what do they do mini robots just dont disappear...
According to Dr Carrie Madej and former FEMA insider Celeste Solum, the DARPA Nanoparticles or Nanotech which is known as "Hydrogel" is apparently supposed to slowly modify your body and convert it into a sort of "receiver" to connect and link up to technology, and it may or may not react to frequencies, signals and smart devices, and also the pentagon is researching bio sensors to detect viruses or tell you if you are sick before the symptoms even start, and there was a Microsoft patent for a human cryptocurrency mining system which according to the diagram requires a bio sensor that collects body data, a communication network which may be some form of advanced AI and 5G, a user device, a phone for instance, and a Crypto system which would probably be a legally mandated one world digital currency that ends up replacing the dollar bill, in order to work, so, make of that what you will...
As far as I know, scientists are trying to predict what strains of the flu virus will be next year. For greater confidence vaccines are made as a mixture of several vaccines against the most likely stamps of the virus.
The flu vaccine has been around for years, they simply tweak it each year depending on the influenza viruses going around. Likewise, the Pfizer and Moderna vaccines have been in the making for years, not for COVID-19, but as a broad-range anti-viral vaccine.
The body doesn't know vaccines, so obviously it will target the molecule. It doesn't know that this molecule is helpful as opposed to all the other freeloating RNAs. How is it supposed to know that?
@@solar0wind correct me if im wrong. it seems to me that some molecules cannot get to enter certain cells or cross certain membrance because either the ribonuclease destroys it or they are just too big. so this virus is altered both in size and structure so it gets pass these barriers... it is also understood from the video that the restructuring of this virus allows other materials to be attached to it and be carried to certain sites that this added material will be attracted to. that part to me is worrying :( or did my paranoia caused me to hear what i wanna hear
What happens to the “little nano bubbles ” that transported the package? I am seeing anti-vacs info regarding “Poly(ethylene glycol) “ being used in the nanoparticles and am concerns about this substance being poisonous to the human body? Do these little nano particles just float around until we die, or does the body eliminate them. Can they become electromagnetically charged and do damage? I am curious about this as I have taken the Pfizer-Biotech shots.
Not just that but also mutatations and brain or control over parts of your body with the magneto protein tech..they are eventually nano particles right
Have the same question! Were you able to find an answer to this question? Agh what happens to the damn lipid nanoparticles after, can't seem to find an answer anywhere!
Hi misstruthseek, thanks for you comment. Having your DNA modified is a real risk with DNA vaccines. But RNA vaccines work differently. The introduced RNA does not enter the nucleus and does not interact with your DNA at all. After the RNA is translated to protein, it is degraded by ribonucleases.
@@seanpadraigobrien1260 Hi Metaphysical Jester. Thanks for making the connection to the Pfizer / BioNTech vaccine! There are several companies and organizations developing mRNA (or RNA) vaccines against COVID-19 including Moderna and Sanofi (with their partner Translate Bio). Basically they all work the same way. The concept is to introduce the instructions for a protein in the form of mRNA to a person's cell. The cell will then make the protein which then serves as an antigen to elicit an immune response. This is a shortcut to manufacturing the protein or creating a weakened virus. In essence, delivering the mRNA to the cell is making the patient makes their own vaccine! The BIG problem that has to be overcome is how to get the RNA molecule into the body and to the cell. This is where the lipid nanoparticles come in. The lipid nanoparticles (LNP's) are a delivery device. They allow the "packaging" of the delicate RNA molecules at a nano-scale. The LNP's serve two purposes 1) protect the RNA from the enzymes that destroy them--ribonucleases, and 2) allow the RNA to be taken up by the cell through endocytosis.
@Growler Thunder wow no reply to this one. They wanna trick as many people as they can to take this. Vaccines with nanobots in it. Thats crazy and people will still take this. This leads to biometric id and 5g system
At 3:59 : If ligands are added on the surface of the nanoparticle, there is a risk of destruction of the nanoparticle before it enters the cell. Because dendritic cells may recognize this ligands as antigen and may neutrilize them. Therfore the mRNA inside will be also destructed and will not be able to enter the cell.
If that was the case then in the theory the RNA should just float around in your blood because it has no were else to go. It’s to big of a molecule to escape the bloodstream. It should just degrade or your body will take of it. I think the scary question your missing Is what damage it will to your body once it’s in your cell.
@ScienceSketch Hi, thank you for the video, but can you please explain how exactly the nanoparticles are degraded by the body? Secondly, let's say I have all my ACE-2 receptors blocked/covered, and so the vaccine cannot bind to any of the cells...What would hypothetically then happen to the mRNA-lipid nanoparticle package?
Yes, the genome was sequenced in late 2019 by a research group in China led by Professor Zhang. A consortium led by Dr. Zhang of the Shanghai Public Health Clinical Center & School of Public Health that posted the sequence on an open-access site, virological.org. Here are some links for more information. time.com/5882918/zhang-yongzhen-interview-china-coronavirus-genome www.sciencemag.org/news/2020/01/chinese-researchers-reveal-draft-genome-virus-implicated-wuhan-pneumonia-outbreak
Yes, my estimation of humanity took a turn for the worse since 2020. These pharma companies really do a good job of covering up their criminality from the general public.
Data is now showing that the lipids travel throughout the body in the days following the injection. Then they accumulate in such areas as the spleen and bone marrow. What is the explanation for this, will these lipids eventually break down or is this cause for concern?
Do the nanoparticles enter not only lymphoid tissues but the bloodstream and then gain entry to various cell types other than dendritic cells? If yes, can the result be presentation of the antigen or any other molecule on the cell surface provoking an immune reaction against the cell--that is, an autoimmune reaction?
The lipid nanoparticles are not specific to dendritic cells. They can interact with other cell types. But it is only the antigen presenting cells which display the protein on the outside of the cell and activate the immune system to create antibodies and memory B cells.
@@ScienceSketch Are the lipid nanoparticles themselves not immunogenic, if they cohere with, say, the membranes of endothelial cells? By what mechanisms are the spike proteins expressed as a result of immunization finding their way to the ACE receptors on platelets--if here I have right the current thinking about the cause of clotting that has become of concern?
how can the mrna escape the endosome ? several studies show that only 2% of the mrna escape from the degradation and arrive to the ribosome. how can you be sure that this delivery system works ? and what about the side effects ??
Thanks for the in-depth science about this new type of vaccine. I genuinely do think that this type of vaccine is revolutionary and is the way forward as it has many advantages over traditional vaccines, but I wish they were tested a lot more extensively, especially for long-term effects, because this is the first time we have a vaccine of this type widely used. For this reason, the prospect of people being forced to take them or be denied access to public areas or airplanes is scary. I do have one question though and it's something I've been wondering about that the media never wants to mention. What about people who have already been infected by SARS-CoV-2 and have recovered? Surely these people already have the necessary immunity in place, such as memory T-cells. Is there any difference in the immunity given by this vaccine to the naturally acquired immunity?
Hi Matthew, great observations and questions. I agree that the mRNA vaccines are a very exciting development. They are first of their kind. The speed at which an mRNA vaccine can be applied to a new virus is amazing and bodes well for combatting novel viruses that will crop in the future. And they will. Also mRNA vaccines have huge potential for treating cancer. As far as how well the vaccines work versus natural immunity, we don't know yet. We have to get more data, particularly longitudinal data to make any conclusions. It is conceivable that infection will give immunity but that the immunity will diminish over time. This is the case for other coronaviruses. A vaccine, therefore, may give a more robust and longer-lasting immunity. But then again it could turn out that you need a booster shot periodically to maintain strong immunity. We will see!
@@ScienceSketch Thanks for a very quick reply! The diminishing immunity to other coronaviruses, is that inclusive of memory cell count in the body or just the antibodies? This was something that bothered me greatly about media reporting, because they only focused on antibody numbers going down, but no mention of memory cells, which are known to last for a long time. There are also scientific studies out there of memory cells against other coronaviruses being able to launch a quick immune response to SARS-CoV-2 due to many similarities in the spike protein, and this is also something that media never talks about. So, I'd be very curious to see if anything will be different with the vaccine.
Hi Matthew, the antibodies against SARS CoV-2 last at least 5 months by some measures. After vaccination with the Moderna mRNA vaccine, there were antibodies at the 4-month mark and they may remain for much longer. You made an astute point about antibodies not being the whole story. Memory B cells persist for a long time and can orchestrate a quick response to future infection. I was not aware of the studies showing that memory B cells from previous coronavirus infection can respond to SARS-CoV-2. That makes a lot of sense though. The spike protein is somewhat conserved across coronaviruses. Interesting!
@@ScienceSketch Thanks for the reply again, ScienceSketch. Well, I do hope the vaccines prove to be effective. I think we all want to return to normality as soon as possible. Though since the virus can mutate (though not as fast as flu viruses), I'd guess there's a good chance that vaccination might have to be done regularly, like every year or maybe after every few years. But yes, this is certainly good that our immune system can use memory "blueprints" of other coronaviruses in order to deal with this one. And maybe this will be one of the keys in developing treatments against SARS-CoV-2. I think all these new developments will be useful in dealing with future disease outbreaks too. Thanks again for the response. :)
@@MatthewAshworth forget about all this that planned and orchestrated to create fear and facilitate the GLOBAL GREAT RESET...IVERMECTIN may prove much better then this !..not to mention much cheaper and safer !
Can you please explain the following at 2:41 : "the nano particles are absorbed in the body and taken up by an antigen presenting cell eg a dendritic cell or B cell through endocytosis." I don't understand what the dendritic cell or B cell are doing during the endocytosis. Dendritic cells and B cells are our immune system cells, why do they come into game during endocytosis ? Our immune system army shows up only when the spike protein is produced and the spike protein is displayed on the surface of the cell. Am I wrong ? Can you please explain.
Excellent production👍 but a question, made in less than a year 🤔 tested on 1 billion people +, what’s the outlook in rna/dna, say in 1,5,10, or 20 years..........or offspring.......🤫 Just asking ..........
Would the cytotoxic t cell not attack the host cell presenting the s spike protein on MHC 1? Don't Cytotoxic t-cells attack cells presenting foreign antigens on MHC-1 like during a viral infection?
Hi James, thanks for your question. It is true that any nucleated cell that is infected will display the foreign antigens on MHC1, and that T lymphocytes can detect the displayed antigen and respond. When a professional antigen presenting cell (APC) such as a dendritic cell presents foreign antigen on MHC1, then interaction of immature CD-8+ T cells with the antigen being presented on MHC1 leads to the development of a mature cytotoxic T cell. It may be that the APC displaying the foreign antigen on MHC1 is “protected” and that its only role is the activation of immature T cells. I would like to find a clear statement to this effect, but not finding it. One of the critical events after vaccination is the development of antibodies to the foreign protein (the video did not pursue this process). One key difference is that antibodies can bind the whole antigen, whereas the T cell receptor can only bind to the fragment of the antigen when it is displayed on MHC.
@@ScienceSketch So i watched your video again and noticed this time that ligands on the nanoparticles can target immune cells. So no non immune cells would synthesize the viral proteins. Correct me if I'm wrong but immune cells are protected because they present on MHC2 while non immune cells present on MHC1. Do you know if the moderna and pfizer vaccines are targeting immune cells through the use of ligands?
The LNP's can incorporate components that will bias them to tissues where there are more antigen presenting cells, but to my knowledge, the LNPs will still interact with non immune cells. Both MCH1 and MCH2 are in play in dendritic cells. The proteins that are synthesized in the cell (including the viral proteins encoded by the vaccine RNA) are processed by the proteasome and the endoplasmic reticulum and then conjugated with MHC1 and are displayed at the cell surface to CD8+ T cells. The proteins that are brought in to the cell through endocytosis are conjugated to MHC2 and then displayed at the cell surface to CD4+ T cells. I don't have any information about the composition of Moderna's or Pfizer's LNP's. A very good review article is Therapeutic Delivery (2016) 7(5) 319-334. The PDF is available from the website of one of the co-authors, Ana Jaklenec at MIT. Here's the link: jaklenecgroup.mit.edu/sites/default/files/images/Reichmuth%20et%20al.pdf
James, thank you for watching and processing what you have seen. Your pertinent questions have made me realize that there are many aspects of immunology that I do not understand. It is important that we embrace the fact that we do not know everything. Instead of fearing the unknown (as I am afraid so many commenters do...) we need to celebrate: nature is complicated, science is empirical, and there is a lot out there to learn.
@@Umu_Eri yes, you’re correct. Idk if I just accidentally forgot to type it but my original comment was supposed to say “These vaccines are no longer a conspiracy theory.”
They were considered conspiracy theories to those who didnt want to hear what has been fact from the get go. They never were conspiracy theories. Just uncomfortable truths.
Yes, the cells presenting pieces of the Spike protein are seen by the immune system as being infected. The T-cells that interact with these cells don't just take a sample of the Spike protein from the cell that produced it and go off to create immunity, they also mark the cell for destruction. My worry is not with muscle cells at the injection site getting destroyed by killer T-cells. I am worried about the lipids getting in the bloodstream and being taken up in random spots by endothelial cells in the lining of the blood vessels. When those cells produce spike protein the worry is the immune system destroying pieces of the lining of the blood vessels leading to inflammation and micro blood clots in thousands of different locations in a short period of time. It is difficult to find information about the Trophism* (what tissues it can penetrate) of the Lipid Nanoparticles used in the vaccine. I take a vitamin supplement that is encapsulated with this same technology of a bi-layer phospho-lipid sphere. My vitamins are great because the lipid micro spheres go EVERYWHERE with ease. They even cross the blood/brain barrier which helps deliver specialized supplements to the brain that are normally difficult to do. The lipid Nano spheres even fuse with tumor cell membranes, which is great because that means you can get vitamin C into the tumor, which resists absorbing naked vitamin C from the bloodstream. So my question is what is the exposure of the central nervous system and the vascular system to absorbing the lipids from the vaccine.
@@earlrobinson5911 yeees that is exactly why I ask that. I've heard of people not being able to walk after the vaccine and I wondered if maybe too many nervous system cells got infected with the mRNA therefore attacked. I'm no scientist and only studied biology in school. This should be something obvious in the scientific community yet there is nothing. And because there is nothing is that it just makes it all the more worrisome. Thank you very much for answering and at least I don't feel so alone in thinking this.
@@ScienceSketch But what commercial sources? A lipid is a fat, right? So, it comes from a living organism such as an animal, plant, or human. So, my question is where are the lipids derived from that are used in the Covid mRNA vaccines? The ingredients list simply says lipids, but that is extremely vague. That would be like saying a food contains fat on the ingredients list instead of stating the actual ingredient that provides the fat.
Hi Jessica, OK, you asked for it! The exact formulations are proprietary. That is, each company has its own “recipe” to make lipid nanoparticles. As part of the application for EUA (emergency use authorization), each company has to disclose to the FDA, the exact formulation that is used in the vaccine. This information is publicly accessible, but you have to hunt for it. I carried out some hunting on your behalf. For the Pfizer/BioNTech vaccine, the ingredients are given in this document: www.fda.gov/media/144413/download Section 13 lists “lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg 2[(polyethylene glycol)-2000]- N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-phosphocholine, and 0.2 mg cholesterol).” Most of these are synthetic lipids. That is, they are made in a laboratory, not isolated from a plant or animal. If I had to guess, the only naturally occurring one is cholesterol which is probably isolated from chicken eggs, and then highly purified. You can look up the other components in google.
@@ScienceSketch thank you so much. I will read the information you provided. Once the vaccines become fully approved will the FDA have the companies be more transparent?
@@ScienceSketch also thank you for taking the time to introduce me to synthetic lipids. I didn't know this existed! I looked it up and learned about synthetic and semi-synthetic. I read that most semi-synthetic are made with soybeans. I plan to search the 4 lipids that Pfizer provides and see if I can find out what type they are. Thank you for giving me a starting point. I am searching this due to severe food allergies within my family. Do you know if there is potential for a lipid derived from a plant or animal to actually produce an allergic reaction, or would the purification process remove the proteins that tend to cause a reaction?
@@alonnaharris736 Yes, Joyful is right. These are lipid nanoparticles, NLPs, completely synthetic and highly allergenic. They've already been forced to put out warnings that people w/ allergies shouldn't take these frankenvaxes. So much experimental, gene therapy technology, irresponsibly rushed out.
I would love to see you make a video about magnetic nanoparticles used in dna vaccines. I believe this is the reason magnets are sticking to some people's arms. I know the science is real. I've done on people myself on the vaxxed and it works!
@@electron7659 from what I've read the ionized nanoparticles are use for the delivery of the protein, allowing the body to take it and nor destroy it as it would normally. As far a 5g I have not seen any evidence they are connected.
He doesn't mention the particles as magnetic, so he is either ignorant or concealing information. I think it's the former. It should be shown that these nanoparticles are partly metallic. That is what makes them electric.
I don't actually understand very well what was said, but, if this tech is truly a solution, why he hasn't there been a vaccine created for HIV deploying this technology?
Can you comment to any extent the effect these Lipid Nanoparticles might have on the Liver? And how they might interact with medications people take (i.e. Acetaminophen, etc)
Hi, great questions... I don't have any information on these topics. I would expect that lipid nanoparticles would be cleared in the lymph nodes (lymphatic system). How much liver exposure there would be is unclear. As far as drug interactions are concerned, based on the mechanism of of action, I would not expect RNA vaccines to inhibit drug metabolism (for example, cytochrome p450 inhibition) so I think it unlikely that there would be a direct interaction on other common medications, but again, I have no data on this question. Thanks for watching!
@@ScienceSketch The particles go to the liver, they are designed for liver treatment, but are working well as vaccines. Arbutus owns the patent to the technology, Moderna is using Arbutus technology without permission.
@@paul1974 that’s probably why my grandma developed cirrhosis after her double shot. She was healthy with no problems, everything tested 2 years ago and now she has 15 diseases. Cirrhosis, Pre diabetes, motor neurone damage, thrombosis literally everywhere. It’s a mess and it looks like hell.
The lipid nanoparticles are made out of lipids. You can find the exact ingredients used at FDA.gov. There are no nanobots. No autonomous function at all. The mRNA vaccines triggers the synthesis of a viral protein. Then the nanoparticles are degraded by your body.
The following document shows the components of the lipid layer. Scroll to page 4 to see the chart. www.cdc.gov/vaccines/covid-19/downloads/pre-vaccination-screening-form.pdf
@@ScienceSketch Hi, thank you for the video, but can you please explain how exactly the nanoparticles are degraded by the body? Secondly, let's say I have all my ACE-2 receptors blocked/covered, and so the vaccine cannot bind to any of the cells...What would hypothetically then happen to the mRNA-lipidnanopartical package?
@@ScienceSketch while you explain the LNPs possibly being more “selective” they aren’t there yet. So when people are getting the jabs now, the LNPs and their subsequent mRNA payloads are setting up shop in places like the heart, causing spike proteins to be created in heart cells, causing an immune/inflammatory response in the heart. The whole process is pretty janky. And to that end, since you are only producing 1 type of protein and not a complete protein picture to the immune system, the immune system is still behind the curve, leading it to being extremely “leaky” to the point where it isn’t even a vaccine, it is a therapeutic. As it doesn’t prevent infection or spread, but instead lesses symptoms; a therapeutic.
@@UniversalMind-10 I have had to jump all around on the internet, honestly. I want to have as an informed decision on these “vaccines” as possible. There are some videos on here that explain the mechanics very well. Scientific papers are out there to dig up, if you are inclined to read them, you’ll find that LNPs, were designed to have many various rolls, based on their construction. Even as a medicine delivery system, to even help structurally repair heart tissue. Unfortunately, in my opinion, in the rush of development, I believe we got an extremely poor vaccine out of it. Can it improve, absolutely, but I am a skeptical early adopter. I try not to get a first generation anything, like vehicles or electronics, and certainly not medicine, unless the reward outweighs the risk. The true test will be later on down the road, when I suspect they will want to replace all current traditional vaccines with mRNA types, to maximize production and reduce cost, so they had to get a proof of concept with a largely survivable virus. If they tried this with, lets say, polio, and it failed, this technology would not see the light of day. For me, until they address the selectivity and fidelity of mRNA to produce antigens, I am not sold.
Ribonucleic sole purpose of existing is to destroy bits of rna.. so once the lipid nanoparticles releases it what stops from still destroying it?? .. help me understand
I have a question regarding the protein being administered. If the virus mutates, then it will have different proteins, so does the vaccine become in affective?
With the mRNA vaccines, it is actually mRNA that is administered, not the protein. The variants (viral mutations) do affect the efficacy of some of the vaccines. Most of the vaccines appear to be effective against the UK variant B.1.1.7. On the other hand, the Oxford Astra Zeneca, Johnson Johnson, and Novavax vaccines are less effective against the South African variant 501Y.V2. Here's an article for more information: www.ft.com/content/e9bbd4fe-e6bf-4383-bfd3-be64140a3f36 The virus will continue to mutate as it passes through humans. So the important thing is that we stamp out this virus as quickly as possible using the vaccines that we have.
Yes it has been. The virus was first isolated in China on Jan 7, 2020 and the genome sequence was published three days later. www.ncbi.nlm.nih.gov/pmc/articles/PMC7098030/ and www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/
Do nanoparticles have free access to cells? Is that why moderna is using Nanoparticles to deliver the mRNA into the cell? Question: is a virus itself also considered a nanoparticle? If so then why don’t they have free access into cells but need a lock and key mechanism to enter cells?
Thanks for your great questions. The SARS CoV-2 virus is a lot like a lipid nanoparticle (LNP)-basically a lipid shell with some proteins surrounding an RNA package. LNP’s have free access to cells, and they are brought into cells through a process called endocytosis. The SARS CoV-2 virus uses the spike protein to specifically bind to cells which display the ACE-2 receptor. In that way, the virus directs itself to certain cell types in the human body. The ACE-2 receptor is found in the tissue lining the lung, in the intestinal tract and in other tissues. After binding to the ACE-2 receptor, the virus is brought into the cell as the ACE-2 receptor is pulled into the cell. The LNP’s (to my knowledge) don’t have a specific way to target certain cells over others, although the next generation of them may have the capability to do that.
@@ScienceSketch I guess you know there are videos going around where it shows magnets sticking to people's injection sites. The videos seem to be legit, not faked for whatever reason. I think the very first one that went viral was in the U.K., but a number of reports in the U.S. as well. I've been trying to see if there cannot be some reasonable explanation for it such as magnetic nanoparticles or even things like iron oxide being part of the vaccines. What people are saying is that they believe they're being chipped for tracking!!! To be clear, I do not believe that, but this is going around and I think it needs to be put to rest or proven false. I'm just looking for answers.
Several strains of the virus have been isolated from patients by research groups around the world. The first time that the SARS CoV-2 virus was isolated from a patient and its RNA genome was sequenced was by a research group led by Peng Zhou from the Wuhan Institute of Virology in China. The virus has also been visualized by electron microscopy showing the characteristic spikes.
@Dr Darren There is a huge number of published covid genomes. You can find them here is you wish to look at them www.ncbi.nlm.nih.gov/datasets/coronavirus/genomes/
In this video, I seen that it can take years to have a new vaccine for a virus. There is a certain process how RNA works, in how it can attack the virus. I am very amaze in how in our bodies work. I often familiarize this COVID19 virus to the flu. Many of us do not take the flu shot because it has been here for several years, and we do not often hear people dying from the flu because of our lack of knowledge, but we should take knowledge that everyone should put the flu shot as well as the covid shot to decrease further spreading.
thing is,you dont dont talk about the disadvantages of nanoparticles... neither did you mention the hiv fragments used to enter the nucleus, which covid has
Do you have a science journal or article that explains this further? I would love any sited sources of information. I want to educate others about the dangers of this new mRNA vaccine. Definitely would appreciate it!
@@hurricanehan6073 Anthony Patch , on youtube, has a video called “Retrovirus Retrospective”. He dives deep into detail about covid, its strains, spike proteins and what the future can look forward to considering a vaccine and electroporation. I couldnt find the source he mentions about the HIV-1 fragments, although he goes very into detail. Here is one of the sources Anthony Patch uses in his presentation: www.biorxiv.org/content/10.1101/2020.12.12.422516v1 Talks about reverse transcription of Sars-Covid-2 RNA
@Shobah- I have been researching scientific journals, research, animal challenge studies related to human coronaviruses,SARS-CoV, coronavirus therapeutics&potential vaccines and the like since the first mention of SARS-CoV 2. I actually read the past research associated with “Gain of Function” studies done in association with (SARS)coronaviruses and how they utilize HIV Look under pseudovirus production in this article academic.oup.com/jid/article/218/2/197/4810771 www.the-scientist.com/the-nutshell/moratorium-on-gain-of-function-research-36564 www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502 Lentiviral and or Lentivirus is HIV-1 www.ncbi.nlm.nih.gov/pmc/articles/PMC1635018/#!po=1.06383 Vector viruses www.creative-biolabs.com/vaccine/lentivirus-as-vaccine-vectors.htm
@Shobah- Thanks for the information links! Much appreciated Another link to HIV and CoVid. www.dr-rath-foundation.org/2020/04/nobel-prize-winning-scientist-who-discovered-hiv-says-coronavirus-was-created-in-laboratory/ He also mentioned Malaria www.neweurope.eu/article/nobel-winning-scientist-says-covid-19-originated-in-wuhan-lab/
These particles are quickly becoming the new toxin gambit, like mercury in traditional vaccines. It's easier to make large quantities of RNA than it is to make large quantities of proteins, but I believe they have to be stored at ultralow temperatures using -80°C freezers that cost upwards of $10k. Great job with the video, throughly enjoyed
Very nice explaination, detailed and understandable. When the antigen is displayed on our own cells where it is recognized by the immune system, I would like to know what will happens as the immune system will start fighting our own cells with this new antigen display on its surface. It might be that the antigen are just release outside the cell, not causing the LT to attack the cells but only the antigen ? And also if you have time, how does the vaccine target specific cells and will not spread in your body to integrate mRNA in cells like neurons. Thanks :)
Hi Bastronom, thanks for your great questions. As far as the adaptive immune response is concerned, the key to targeting infected cells and not healthy cells is the MHC (major histocompatibility complex). All cells (not only antigen presenting cells) can process foreign proteins (e.g. virus protein) and bind the epitope to MHC1 which are presented on the outside of the cell where they interact with CD8+ T killer cells. But here is the key: endogenous proteins from the host are also degraded and presented as epitopes. The presentation of self-antigens on MHC1 prevents your immune system from targeting your cells. The immune system is astonishingly complex, and I would suggest that you refer to on-line sources for more information. With respect to your second question about the vaccine targeting specific cells...It is known that dendritic cells are covered with lectins that recognize carbohydrates. It has been found that decorating lipid nanoparticles with carbohydrates (e.g. highly mannosylated lipids) can increase the potency of vaccines.
@@ScienceSketch are these lipid nanoparticles biological how do they know where to go is it similar to the way a plant would move nutrients from one cell to another or are we talking about microscopic machines that are programed to go where we tell them. I would like to understand how the RNA knows where to go and how its better to let a synthetic strand into a cell rather then a viral one. Any suggested videos or reading would be appreciatedd. Great video @ScienceSketch and great question @Bastronom
@@malcolmmomotiuk7744 Thanks for your questions. The lipid nanoparticles (LNP's) are man-made, not biological and they don't really know where to go. They are not programmed robots or machines. They are absorbed by the body, and are exposed to many tissues and cell types in the body. The cells that are most important for eliciting an immune response are the dendritic cells. The vaccine makers insert a synthetic strand into the LNP which codes for the spike protein. The viral strand would code for the whole virus and cause proliferation of the virus inside the body, and we don't want that! For further reading, I would recommend the two references in the description of the video. Unfortunately, the Future Science paper is not open access so you need to access it through your library or institution. The Nature paper is open access, but doesn't have as much detailed information about mRNA vaccines. Nature Nanotechnology, Vol 15, 2020, 646-655. Insert that citation into your Google search bar, and it will take your there. Also I would recommend Wikipedia for definitions of general terms and explaining immunology concepts.
You're talking about micelles. Lipid nanoparticles encapsulate mRNA using an ionizable cationic lipid, the centre is lipid, and the membrane is not a bilayer
Hi Paul, thanks for your comment. Perhaps there is some confusion in terminology? A micelle is a lipid monolayer with a lipophilic center (en.wikipedia.org/wiki/Micelle). A liposome is a bilayer with an aqueous center in which the lipid is primarily a phospholipid. From my primary source which is cited in the description, "Lipid nanoparticles generally consist of an aqueous core surrounded by a lipid bilayer shell that is made of a combination of different lipids." and "Indeed, water-soluble molecules, such as proteins and carbohydrates, can be entrapped within the LNP aqueous core, whereas lipophilic compounds can be incorporated into the LNP lipid bilayer..." From Therapeutic Delivery (2016), 7(5), 319 - 334.
@@ScienceSketch Yes sorry I meant liposomes. The source is incorrect. I am working at a leading mRNA LNP company in formulation and the LNP you are meant to be referring to has a hydrophobic core. I havent read your source but they may be referring to lipid nanoparticles as a class, which includes liposomes and micelles, but are certainly not what the covid vaccines are made from. Try reading Pieter Cullis papers around entrapment of nucleic acids in LNP, there are many papers discussing the structure, the cationic lipid and cholesterol forming a droplet in the centre of a single layer of phospholipid, where mRNA is entrapped due to charge interactions, and PEG stabilizers on the outside.
Thanks for the clarification, Paul, and thanks for sharing your expertise in this area. The review article that I am using for the video (Therapeutic Delivery (2016), 7(5), 319 - 334) concerns lipid nanoparticles specifically for the delivery of mRNA as vaccines. In fact, the title of the review is "mRNA vaccine delivery using lipid nanoparticles." The review article cites papers by Pieter Cullis, a world leader in the field of nucleic acid delivery (primarily mRNA & siRNA) using LNP's. A recent review by Prof Cullis discusses lipid nanoparticles as I have depicted them "size in the range of 100 nm and containing a single bilayer separating the interior aqueous medium from the exterior." Lipid Nanoparticle Systems for Enabling Gene Therapies, Molecular Therapy, Vol. 25(7), 5 July 2017, p. 1467-1475, by Pieter R. Cullis and Michael J. Hope. There are a variety of formulation technologies that the vaccine companies are using. The specific formulations are proprietary, and not shared publicly. There are going to be patent infringement cases and cross-licensing arrangements that are going to take a while to sort out.
Your video is very nice. Thank you very much. I would like to know the following : When our body is making its own mRNA, which goes outside the nucleus to cytoplasm, this mRNA is not protected by lipid nanoparticle as it is the case in the vaccine. Therefore why doensn't the ribonuclease cause the degradation of the mRNA ?
Hi Zehra, thank you for your kind comments. Great question! As you point out, your endogenous mRNA is not protected by lipid nanoparticles and is subject to degradation by ribonucleases. True! Nevertheless, the mRNA has a sufficiently long half-life to allow the translation of mRNA to protein. Then, at some point, its job is done, and the mRNA is degraded, thus halting the production of protein. It is a carefully controlled and beautifully orchestrated system. There are a lot of factors responsible for the stability of the mRNA in the cytoplasm...too complicated to elaborate in this forum. I would urge you to pursue this question using on-line resources. Without the lipid nanoparticles (LNPs), the RNA from the vaccine would not even make it to the cell. Even the surface of your skin has ribonucleases. So it is essential that the exogenous RNA be protected with the LNP.
@@ScienceSketch that is an excellent point, a phenomenally fine tuned system. You know that when DNA is tinkered with, removing faulty genes, upregulating, downregulating and so on, there are unexpected and often catastrophic effects. I am curious if you can see that there might be similar unexpected problems with introducing synthetic mRNA and synthetic lipids into such a fine tuned system?
Absolutely! That's why we do clinical trials. It is only in the trials that, first and foremost, safety can be established and second, efficacy can be established. Safety always comes first. The phase I trials are done very carefully with small, single doses and careful observation, monitoring vital signs and doing blood work. Only when it has proven safe, does it go into more volunteers with multiple doses. In the case of mRNA vaccines, the hypothesis is that because mRNA is so fragile that it will do its job and then be degraded quickly. Only the acquired immunity lasts. One theme that I have noticed in the comments in this forum, is that many people look at SCIENCE as a big monolithic rule book, but in reality science is all about experimentation and observation. Science is empirical. Every drug and vaccine starts out as a testable hypothesis. Only after carrying out the carefully controlled experiment (in this case the safety and efficacy of a vaccine), can a reasonable decision be made to progress.
@@ScienceSketch I can see that you love science, and that you have great faith in scientists and their desire to do good things for humanity. And I think that is a wonderful, admirable perspective. I love science too, and my children are engineers and mathematicians. We are a STEM family. But as an older person with what we call "the long view" of humanity, i have simply seen far too often that money corrupts and power corrupts. I very strongly disagree with the statement that these trials were done carefully, these vaxxes are a grand experiment being carried out on millions of humans. The people who have died and will die from this vaccine mattered to the ones who love them, just as I am sure that you matter to those who love you. Imagine how they would feel if you took the vaccine and died within hours or days. You aren't a statistic, you are a valuable human being and your life matters, just as their lives mattered too. There is a difference between dying of something and dying from something that was supposed to protect from getting sick. I can see that you have a thirst for knowledge, and that's a wonderful quality. I an going to pray for you, I am going to ask God to show you the truth, to give you knowledge about this matter from God's perspective. I do appreciate your response. God bless you
Its the mark of the beast. This is what God has warned us from for thousands of years. Many will be deceived, many will perish for a lack of knowledge. Not straight away, but when the wrath comes. Seek God now, jesus is waiting for you, he loves you but you need to deny satan all the way.
I learned how decades of making a vaccine was done in less than a year. It is amazing to see how instead of injecting the body with dead or less strong viruses they can inject the body with MRNA which gives our cells the instructions to make defense against the virus.
You've got it Muhammed! Very cool stuff. A lot of the early work on mRNA vaccines had been going for years. It was mostly for Ebola and other deadly viruses. But when Covid came along, the scientists could easily pivot and align the technology platform against this new threat. Thanks for watching.
No, thank you.
@@lookingup9041 I'm with you. I've seen the damage these cause up close and personal. I lost my dad to one of these.
@@Sara-gl8ue Now, I am hearing of people suddenly dying in their sleep from heart attacks. We are burying my 51 year old female cousin this Monday from that. And today I just heard of a 37 year old mother of an 11 year old who also suddenly died of a heart attack in her sleep. She was a nurse’s aid in a nursing home. All these sudden and excess deaths due to heart attacks and other reasons. So, once again…NO, THANK YOU!
@@lookingup9041 I'm so sorry for your loss. I currently have a cousin in the hospital because of a brain aneurysm. She's young and healthy but she did get vaxxed because of her job.
A friend of mine just posted about her friend dying suddenly and unexpectedly in her sleep. She was in her early 40s and was a nurse, so I can only assume she was vaxxed. Something isn't right.....
And now, according to Japanese research, lipid nanoparticles are found in large quantities in bone marrow and ovaries. Which means the mRna is migrating to other parts of the body and no one knows the long term effects.
Dark horse podcast? I just learned this yesterday
@@kaka7654 Yes this is very scary, but the majority have no idea.
@@robertmckinnon6564 indeed. Its their own ignorance that will be their downfall.
Can you give me the podcast episode? & the timestamp if possible?
@@jpapi2778 look for Christopher Lopez channel on this platform and you'll find Robert Malone talking about mRNA. It was some time last week.
4:19 - The whole world was the clinical trial and we are now seeing the devastating effects.
Man made crisis. Wahlah! A reason to test our pet science on mankind. What could possibly go wrong? 🤦♀️
Let's open Pandoras Box, right?
we have to let them play with their new toys
Inshallah allah guides us all
I have a few questions that seems to be excluded from all mRNA explanation.
What happen to the cell that have made the spikes now that the killer cells have identified them as a virus?
Are they killed in the process?
Do we kill our own cells in order to create the spikes?
Is it correct that the mRNA doesn't only affect cells at the injection site, but also travels throughout the body?
Does the mRNA particles travel across the brain/blood barrier in humans like it does with mice?
What other vital organs does the mRNA reach?
Reaches everything..doesn't stay in the deltoid muscle...
technically, it was suppose to dissolve on it's own, like normal mRNA. And as another security measure, cells generally die over time. This is according to Dr. Been. But I think he might be wrong, as new studies from Germany in July came out suggesting they stay in the cells for over 2mths if not longer, and they do migrate. So...Just go out and enjoy your love ones, and pray that this is all an nothing burger.
What if the body could produce it's own vaccine??
immune system can do this right?
Conventional vaccines introduce a virus protein or attenuated virus. The mRNA vaccines are innovative because they do not introduce a protein or whole virus. Instead, they contain mRNA which codes for a virus protein. Then it is up to the patient to translate the mRNA into protein. In that way, the body is making its own vaccine; i.e. the spike protein which will trigger the immune response.
@@ScienceSketch so it’s gene therapy
Uh... yeah... and natural immunity will "remember" the entire molecule to neutralize at all possible sites not just the spike protein.
A vaccine based on the spike protein will have unknown ability to handle variants with a different spike and of course, that is exactly how the variants differ; a different spike protein. Natural immunity would recognize all of rhe neutralizing sites so common sites (other than the spike) for the variants are still available.
Natural immunity might handle the variants .. while the vaccines will require a new jab for every spike protein variant (vaccine merry-go-round .. not a fun ride).
Natural immunity is way better yet the "narrative" suggests that the vaccine is recommended even for people who got C19. This .. is a ridiculous suggestion since the vaccine "response" will likely overshadow the natural immunity response .... meaning only that only spike protein antibodies might be produced which might not even work. The "other" neutralizing sites might not be targeted after vaccination which reduces the effectiveness of natural immunity. Idiotic .. yet universally suggested.
Thank you for the responses
@@ScienceSketch Internet Of Bio Nano Things..........Internet Of Bodies
I don’t want computers in my body
Exactly its a computer.
Facts
Ohhhhh maaaaan.... Another one eh? Make sure your tinfoil-hat is on nice and straight so that when the government tries to beam into your brain it's deflected 😑 there is no Nano microprocessors or technology being injected into you. Why do you people keep breeding?
@@Twitch_Moderator Actually it is. Nanotechnology. It is an operating system. The information is there for you.
@@Twitch_Moderator - you can’t be that gullible to believe in the goodness of science 🤦🏻♂️
Problem, reaction solution.
Covid Event 201 is a biosecurity psyop to usher in Agenda 21 de-industrialization aka The Great Reset.
See all-cause mortality in your country and compare 2019 to 2020.
Deception, capitulation, eradication
@@jesuschristislord77733 Event 201, released a mere few month before the plandemic. It's just a perfect coincidence, the likes of which a mathematician couldn't calculate. Take that gene therapy anyway and dont' think about it.
@@saintejeannedarc9460 The WHO called covid a pandemic 666 days after the Clade X pandemic scenario. The first case in Wuhan on 1st December 2019 was 66 years 6 months after the CORONAtion of Queen Elizabeth II. In the UK we are now in a lockdown which started on 5th of January 2021. That date fell 66,666 days after Queen Victoria was CORONAted. Our great leader is now saying that lockdown will be eased on 8th of March 2021 meaning the final day is the 7th of March which is the 66th day of the year and coincides with the 7th also being a time span of 66 weeks since first case in Wuhan. The 666th day of Corona will be on 27th of September and will be 116660 days since the coronation of Queen Anne who was born in 1665 the year of the plague just before the Great fire in 1666.....666 rituals
@@Scribe3168 That's all pretty interesting, but it's not going to convince the science crew in here. Thankfully, what is giving them pause is the dodgy and experimental gene therapy nature,and how irresponsibly rushed they are.
What could possibly go wrong? 💀
They forgot to show us how they are delivering that messenger RNA package right into your cells. In the case of the DNA viral vector vaccines, coming out soon, they send their genetic instructions right into your nucleus, where your DNA is. Or that this technology is called gene therapy. Of course the fact checkers are hard at work lying about the gene therapy aspect of the vaxes, but I've seen enough science articles bragging about straight from the title.
I tell you what can possibly go wrong: This mARN vaccine wich is technically a virus since it contains genetic material that infects the cell and hijacks the cell protein synthesis system can cause cancer. A cell that produces foreign proteins can be considered as cancerous cell by the immune system and treated as so. Many forms of cancer are induced by viral infections at first. See HPV virus. Also many plants develop cancer after being injected with various plant viruses.
@@saintejeannedarc9460 hence they use artificial mRNA (AI ) luciferase hydrogel gene editing? It's the beginning of transhumanism possibly?
@@pattydaniels4950 their playing God or at least trying to!
@@nopretribrapture2318 There is no actual hydrogel in the mRNA vaccines. They encapsulate the cell hijacking messages in a lipid nanoparticle shell. Luciferase is generally used for testing. They are gene editing though.
A few issues here... lipid nanoparticles used are mixed with polyethylene glycol and remain on the cell walls (possibly forever), and future viruses can easily invade the cell without entering through the ace2. The inserted mRNA creates the same spike proteins that exist on the sars cov 2 virus, but those spike proteins contain prion-like structures that can break through the BBB and drastically raise the chances of neurological diseases like Alzheimer’s and Parkinson’s. Plus, the antibodies that attack the spike proteins are reprogrammed to become overactive and overwhelm other normal antibodies which are wired to fight other common colds/viruses.
It appears that the effects of sars cov 2 might be amplified with receiving the mRNA vaccine.
You sound like you know better than the bioengineers creating and testing the vaccine? Oh wait, I forgot the TH-cam comment section is peer reviewed
scientists, doctors and bioengineers are human too and they make mistakes sometimes. Did you know that a quarter of a million people die each year due to medical errors?@@112rorz
Forget about GMO foods, next are GMO Humans
Humans 1/3 elimination. Apocalyptic time.
Yep. Human 2.0 is supposedly what they're calling GMO Humans. Almost like an update... This is all so weird, and crazy. The people working on this stuff are connected to some shady sounding projects and foundations, DARPA, Rockefellers, Common Health Pass, Gates Foundation, Agenda 2030 which is the Sustainable Development plan and is being pushed as a "climate crisis" and will by law get people in trouble for using things from nature, synthetic meat, eating insect proteins, living in Smart Cities, and according to sources, the "0 net emission goal" and "fixing poverty goal" may or may not require the culling of the population, meaning they'll kill people to get it done, and replace the reduction with AI, robots, which is exactly the kind of thing that companies like DARPA, Boston Dynamics and others are working on as we speak. This may mean the end of us and the beginning of a synthetic hybrid race, this being Human 2.0.
@@damonnugent1993 shesh 🙃
mRNA does not alter your DNA. tf
@@DrDoomsd but it does alter genetics. GMO
This has never been done before!
Perhaps it was in Noah"s day ??
@@EK-sx9ek Giants, Nephilim that had to be wiped out by the flood.... I remember reading a book about a connection between the Nephilim and aliens, ETs, it was interesting. But yeah, it sounds like they want to make a human hybrid. Human GMOs soon to walk among us? But don't GMOs suffer a degradation and drop in quality? Maybe the modified humans will be sterile, unable to have children, and be under malevolent influence.
@@damonnugent1993 go and watch alien covenant or Prometheus. It's what is coming in 2027
@@damonnugent1993 good we need less people lol
@@CoolDrifty Oh believe me... When things really go out of control for real... Because lemme tell you something... This COVID is just the calm before the actual storm... And when things actually go awry.. in ways we couldn't even begin to imagine... men's hearts will fail them for fear... 2020 was NOTHING... compared to what is coming... I just hope we are able to survive. And I pray to God the needle isn't part of the agenda... I just have this awful feeling in my spirit.. Stay safe, and stay blessed.
Luciferase? Sm-102? Mark of the beast!?
There's no luciferase in the vaccine :)
@@payt01 do your research, dig as it's on the test kit as well
Lucifer means light-bearing in Latin. Lux- light and ferre- bring or carry. They named it luciferase because it was discovered in glowing creatures in nature. The protein that was discovered also allowed scientists to have things glow when we shine a light at it under a microscope making it easy to study very small things and where they are going in and on a cell.
@@Brandon77maniaci well I can send you a video what it's doing to people, glowing veins
@@blakemccloy5190 And magnetic as well, I'm sure, as well as being hooked up to 5G. LOL. I only see advantages, really!
Intresting and disturbing, but what i would like to understand is once there nanoparticles done its job according to this video where do they go and what do they do mini robots just dont disappear...
No answer to that coming soon.......
Morgellons disease
Mini robots stay and wait for 5G activation
According to Dr Carrie Madej and former FEMA insider Celeste Solum, the DARPA Nanoparticles or Nanotech which is known as "Hydrogel" is apparently supposed to slowly modify your body and convert it into a sort of "receiver" to connect and link up to technology, and it may or may not react to frequencies, signals and smart devices, and also the pentagon is researching bio sensors to detect viruses or tell you if you are sick before the symptoms even start, and there was a Microsoft patent for a human cryptocurrency mining system which according to the diagram requires a bio sensor that collects body data, a communication network which may be some form of advanced AI and 5G, a user device, a phone for instance, and a Crypto system which would probably be a legally mandated one world digital currency that ends up replacing the dollar bill, in order to work, so, make of that what you will...
@@damonnugent1993 they will be hooked up to the (world) wide web aka ( the BEAST SYSTEM )
Looks like a Trojan horse to me.
Ha ha haaaa
Genuine question: if it takes years to develop vaccines the conventional way, how do we get seasonal flu vaccines each year?
All I know is the only time I got the flu vaccine i was sick many times that year,
As far as I know, scientists are trying to predict what strains of the flu virus will be next year.
For greater confidence vaccines are made as a mixture of several vaccines against the most likely stamps of the virus.
The flu vaccine has been around for years, they simply tweak it each year depending on the influenza viruses going around. Likewise, the Pfizer and Moderna vaccines have been in the making for years, not for COVID-19, but as a broad-range anti-viral vaccine.
The technology already exists they just tweak it ,
Since learning more about these Covid vaccines, I now have doubts about whether the Flu vaccines have much effect at all.
Time will tell if this becomes a nightmare. A nightmare many will wake up too.
Well if are body is made to fight it off then obviously it isn’t supposed to be in are body
The body doesn't know vaccines, so obviously it will target the molecule. It doesn't know that this molecule is helpful as opposed to all the other freeloating RNAs. How is it supposed to know that?
@@solar0wind correct me if im wrong. it seems to me that some molecules cannot get to enter certain cells or cross certain membrance because either the ribonuclease destroys it or they are just too big. so this virus is altered both in size and structure so it gets pass these barriers... it is also understood from the video that the restructuring of this virus allows other materials to be attached to it and be carried to certain sites that this added material will be attracted to. that part to me is worrying :( or did my paranoia caused me to hear what i wanna hear
To sum it up, don't put this sh!t in your body
What happens to the “little nano bubbles ” that transported the package? I am seeing anti-vacs info regarding “Poly(ethylene glycol) “ being used in the nanoparticles and am concerns about this substance being poisonous to the human body? Do these little nano particles just float around until we die, or does the body eliminate them. Can they become electromagnetically charged and do damage? I am curious about this as I have taken the Pfizer-Biotech shots.
Not just that but also mutatations and brain or control over parts of your body with the magneto protein tech..they are eventually nano particles right
This all is simply not known since all the mrna jabs are EXPIRIMENTAL UNTIL DEC 2023
Have the same question! Were you able to find an answer to this question? Agh what happens to the damn lipid nanoparticles after, can't seem to find an answer anywhere!
No thanks, I don't need my DNA modified.
Hi misstruthseek, thanks for you comment. Having your DNA modified is a real risk with DNA vaccines. But RNA vaccines work differently. The introduced RNA does not enter the nucleus and does not interact with your DNA at all. After the RNA is translated to protein, it is degraded by ribonucleases.
@@ScienceSketch I see the Pfizer Vaccine for covid has lipid nanoparticles in it. Can you explain to laymen how that works ?
@@seanpadraigobrien1260 Hi Metaphysical Jester. Thanks for making the connection to the Pfizer / BioNTech vaccine! There are several companies and organizations developing mRNA (or RNA) vaccines against COVID-19 including Moderna and Sanofi (with their partner Translate Bio). Basically they all work the same way. The concept is to introduce the instructions for a protein in the form of mRNA to a person's cell. The cell will then make the protein which then serves as an antigen to elicit an immune response. This is a shortcut to manufacturing the protein or creating a weakened virus. In essence, delivering the mRNA to the cell is making the patient makes their own vaccine! The BIG problem that has to be overcome is how to get the RNA molecule into the body and to the cell. This is where the lipid nanoparticles come in. The lipid nanoparticles (LNP's) are a delivery device. They allow the "packaging" of the delicate RNA molecules at a nano-scale. The LNP's serve two purposes 1) protect the RNA from the enzymes that destroy them--ribonucleases, and 2) allow the RNA to be taken up by the cell through endocytosis.
@Growler Thunder wow no reply to this one. They wanna trick as many people as they can to take this. Vaccines with nanobots in it. Thats crazy and people will still take this. This leads to biometric id and 5g system
Nanoparticles can cross the blood-brain barrier. So it can cause problems in your brain and it's functions. That's unacceptable.
At 3:59 : If ligands are added on the surface of the nanoparticle, there is a risk of destruction of the nanoparticle before it enters the cell. Because dendritic cells may recognize this ligands as antigen and may neutrilize them. Therfore the mRNA inside will be also destructed and will not be able to enter the cell.
If that was the case then in the theory the RNA should just float around in your blood because it has no were else to go. It’s to big of a molecule to escape the bloodstream. It should just degrade or your body will take of it.
I think the scary question your missing Is what damage it will to your body once it’s in your cell.
@ScienceSketch Hi, thank you for the video, but can you please explain how exactly the nanoparticles are degraded by the body?
Secondly, let's say I have all my ACE-2 receptors blocked/covered, and so the vaccine cannot bind to any of the cells...What would hypothetically then happen to the mRNA-lipid nanoparticle package?
+1
Did you find the answer, I’m very interested in finding out.
My theory is considering it’s a lipid it should be destroyed by enzymes in the cytoplasm.
You indicated the genome was decoded early in the epidemic. Who decoded it?
Yes, the genome was sequenced in late 2019 by a research group in China led by Professor Zhang. A consortium led by Dr. Zhang of the Shanghai Public Health Clinical Center & School of Public Health that posted the sequence on an open-access site, virological.org.
Here are some links for more information.
time.com/5882918/zhang-yongzhen-interview-china-coronavirus-genome
www.sciencemag.org/news/2020/01/chinese-researchers-reveal-draft-genome-virus-implicated-wuhan-pneumonia-outbreak
@@ScienceSketch
Thank you for taking the time and effort to answer and provide links. Very informative.
OMG! S.O.S!
And you trust China, why??
@@Gypsyjonescafe you trust usa ? Why?
Let’s see an actual microscopic presentation of this mRNA technology at work in real live tissue rather than these cartoon representations.
They would never ever expose the lies they spew.
as both a nurse and scientist, it's sad to see easily the public was tricked
Yes, my estimation of humanity took a turn for the worse since 2020. These pharma companies really do a good job of covering up their criminality from the general public.
Data is now showing that the lipids travel throughout the body in the days following the injection. Then they accumulate in such areas as the spleen and bone marrow. What is the explanation for this, will these lipids eventually break down or is this cause for concern?
Do the nanoparticles enter not only lymphoid tissues but the bloodstream and then gain entry to various cell types other than dendritic cells? If yes, can the result be presentation of the antigen or any other molecule on the cell surface provoking an immune reaction against the cell--that is, an autoimmune reaction?
The lipid nanoparticles are not specific to dendritic cells. They can interact with other cell types. But it is only the antigen presenting cells which display the protein on the outside of the cell and activate the immune system to create antibodies and memory B cells.
@@ScienceSketch Are the lipid nanoparticles themselves not immunogenic, if they cohere with, say, the membranes of endothelial cells? By what mechanisms are the spike proteins expressed as a result of immunization finding their way to the ACE receptors on platelets--if here I have right the current thinking about the cause of clotting that has become of concern?
Are MHC1 molecules found on cells outside the immune system? If yes, then can antigen produced by mRNA vaccines be displayed on these cells?
Many people full vaccines with phizer vaccines are positive to COVID.the reason is that lipid nanoparticles did not enter the cell? Thanks a lot.
how can the mrna escape the endosome ? several studies show that only 2% of the mrna escape from the degradation and arrive to the ribosome. how can you be sure that this delivery system works ? and what about the side effects ??
Thanks for the in-depth science about this new type of vaccine. I genuinely do think that this type of vaccine is revolutionary and is the way forward as it has many advantages over traditional vaccines, but I wish they were tested a lot more extensively, especially for long-term effects, because this is the first time we have a vaccine of this type widely used. For this reason, the prospect of people being forced to take them or be denied access to public areas or airplanes is scary. I do have one question though and it's something I've been wondering about that the media never wants to mention. What about people who have already been infected by SARS-CoV-2 and have recovered? Surely these people already have the necessary immunity in place, such as memory T-cells. Is there any difference in the immunity given by this vaccine to the naturally acquired immunity?
Hi Matthew, great observations and questions. I agree that the mRNA vaccines are a very exciting development. They are first of their kind. The speed at which an mRNA vaccine can be applied to a new virus is amazing and bodes well for combatting novel viruses that will crop in the future. And they will. Also mRNA vaccines have huge potential for treating cancer. As far as how well the vaccines work versus natural immunity, we don't know yet. We have to get more data, particularly longitudinal data to make any conclusions. It is conceivable that infection will give immunity but that the immunity will diminish over time. This is the case for other coronaviruses. A vaccine, therefore, may give a more robust and longer-lasting immunity. But then again it could turn out that you need a booster shot periodically to maintain strong immunity. We will see!
@@ScienceSketch Thanks for a very quick reply! The diminishing immunity to other coronaviruses, is that inclusive of memory cell count in the body or just the antibodies? This was something that bothered me greatly about media reporting, because they only focused on antibody numbers going down, but no mention of memory cells, which are known to last for a long time. There are also scientific studies out there of memory cells against other coronaviruses being able to launch a quick immune response to SARS-CoV-2 due to many similarities in the spike protein, and this is also something that media never talks about. So, I'd be very curious to see if anything will be different with the vaccine.
Hi Matthew, the antibodies against SARS CoV-2 last at least 5 months by some measures. After vaccination with the Moderna mRNA vaccine, there were antibodies at the 4-month mark and they may remain for much longer. You made an astute point about antibodies not being the whole story. Memory B cells persist for a long time and can orchestrate a quick response to future infection. I was not aware of the studies showing that memory B cells from previous coronavirus infection can respond to SARS-CoV-2. That makes a lot of sense though. The spike protein is somewhat conserved across coronaviruses. Interesting!
@@ScienceSketch Thanks for the reply again, ScienceSketch. Well, I do hope the vaccines prove to be effective. I think we all want to return to normality as soon as possible. Though since the virus can mutate (though not as fast as flu viruses), I'd guess there's a good chance that vaccination might have to be done regularly, like every year or maybe after every few years. But yes, this is certainly good that our immune system can use memory "blueprints" of other coronaviruses in order to deal with this one. And maybe this will be one of the keys in developing treatments against SARS-CoV-2. I think all these new developments will be useful in dealing with future disease outbreaks too. Thanks again for the response. :)
@@MatthewAshworth forget about all this that planned and orchestrated to create fear and facilitate the GLOBAL GREAT RESET...IVERMECTIN may prove much better then this !..not to mention much cheaper and safer !
turns out it does move from site of injection it fluds the body within 24 hours and collects most in bone marrow and the ovaries
What do you mean by ‘collects’?
Can you please explain the following at 2:41 : "the nano particles are absorbed in the body and taken up by an antigen presenting cell eg a dendritic cell or B cell through endocytosis." I don't understand what the dendritic cell or B cell are doing during the endocytosis. Dendritic cells and B cells are our immune system cells, why do they come into game during endocytosis ? Our immune system army shows up only when the spike protein is produced and the spike protein is displayed on the surface of the cell. Am I wrong ? Can you please explain.
Great question. I hope they answer. I'd like to hear the answer too.
Excellent production👍 but a question, made in less than a year 🤔 tested on 1 billion people +, what’s the outlook in rna/dna, say in 1,5,10, or 20 years..........or offspring.......🤫
Just asking ..........
They don't fucking know. They're playing it by ear
"They exist for a reason". Exactly !!!
Too many people in this world
Would the cytotoxic t cell not attack the host cell presenting the s spike protein on MHC 1? Don't Cytotoxic t-cells attack cells presenting foreign antigens on MHC-1 like during a viral infection?
Hi James, thanks for your question. It is true that any nucleated cell that is infected will display the foreign antigens on MHC1, and that T lymphocytes can detect the displayed antigen and respond. When a professional antigen presenting cell (APC) such as a dendritic cell presents foreign antigen on MHC1, then interaction of immature CD-8+ T cells with the antigen being presented on MHC1 leads to the development of a mature cytotoxic T cell. It may be that the APC displaying the foreign antigen on MHC1 is “protected” and that its only role is the activation of immature T cells. I would like to find a clear statement to this effect, but not finding it.
One of the critical events after vaccination is the development of antibodies to the foreign protein (the video did not pursue this process). One key difference is that antibodies can bind the whole antigen, whereas the T cell receptor can only bind to the fragment of the antigen when it is displayed on MHC.
@@ScienceSketch So i watched your video again and noticed this time that ligands on the nanoparticles can target immune cells. So no non immune cells would synthesize the viral proteins. Correct me if I'm wrong but immune cells are protected because they present on MHC2 while non immune cells present on MHC1. Do you know if the moderna and pfizer vaccines are targeting immune cells through the use of ligands?
The LNP's can incorporate components that will bias them to tissues where there are more antigen presenting cells, but to my knowledge, the LNPs will still interact with non immune cells. Both MCH1 and MCH2 are in play in dendritic cells. The proteins that are synthesized in the cell (including the viral proteins encoded by the vaccine RNA) are processed by the proteasome and the endoplasmic reticulum and then conjugated with MHC1 and are displayed at the cell surface to CD8+ T cells. The proteins that are brought in to the cell through endocytosis are conjugated to MHC2 and then displayed at the cell surface to CD4+ T cells.
I don't have any information about the composition of Moderna's or Pfizer's LNP's.
A very good review article is Therapeutic Delivery (2016) 7(5) 319-334. The PDF is available from the website of one of the co-authors, Ana Jaklenec at MIT. Here's the link:
jaklenecgroup.mit.edu/sites/default/files/images/Reichmuth%20et%20al.pdf
@@ScienceSketch Thank you for taking the time to explain and providing a reference.
James, thank you for watching and processing what you have seen. Your pertinent questions have made me realize that there are many aspects of immunology that I do not understand. It is important that we embrace the fact that we do not know everything. Instead of fearing the unknown (as I am afraid so many commenters do...) we need to celebrate: nature is complicated, science is empirical, and there is a lot out there to learn.
Gene editing, basically. These *vaccines* are no longer a conspiracy theories, I guess🤷♀️
gene editing has existed for a while but not how the conspiracy theories portray it
@@Umu_Eri yes, you’re correct. Idk if I just accidentally forgot to type it but my original comment was supposed to say “These vaccines are no longer a conspiracy theory.”
@@audreyrose1694 ah ok, though i wonder how the vaccines would change the game, it could mean HIV is gonna have its own vaccine
They were considered conspiracy theories to those who didnt want to hear what has been fact from the get go. They never were conspiracy theories. Just uncomfortable truths.
@@Umu_Eri yeah, maybe so
So the cell with the MHC1 would be killed by the T killer cell as it would be recognized as a threat?
Yes, the cells presenting pieces of the Spike protein are seen by the immune system as being infected. The T-cells that interact with these cells don't just take a sample of the Spike protein from the cell that produced it and go off to create immunity, they also mark the cell for destruction.
My worry is not with muscle cells at the injection site getting destroyed by killer T-cells. I am worried about the lipids getting in the bloodstream and being taken up in random spots by endothelial cells in the lining of the blood vessels.
When those cells produce spike protein the worry is the immune system destroying pieces of the lining of the blood vessels leading to inflammation and micro blood clots in thousands of different locations in a short period of time.
It is difficult to find information about the Trophism* (what tissues it can penetrate) of the Lipid Nanoparticles used in the vaccine.
I take a vitamin supplement that is encapsulated with this same technology of a bi-layer phospho-lipid sphere. My vitamins are great because the lipid micro spheres go EVERYWHERE with ease. They even cross the blood/brain barrier which helps deliver specialized supplements to the brain that are normally difficult to do.
The lipid Nano spheres even fuse with tumor cell membranes, which is great because that means you can get vitamin C into the tumor, which resists absorbing naked vitamin C from the bloodstream.
So my question is what is the exposure of the central nervous system and the vascular system to absorbing the lipids from the vaccine.
@@earlrobinson5911 yeees that is exactly why I ask that. I've heard of people not being able to walk after the vaccine and I wondered if maybe too many nervous system cells got infected with the mRNA therefore attacked. I'm no scientist and only studied biology in school. This should be something obvious in the scientific community yet there is nothing. And because there is nothing is that it just makes it all the more worrisome. Thank you very much for answering and at least I don't feel so alone in thinking this.
Can you tell us what living organism(s) is the source for the lipids used?
The lipids used to make the nanoparticles are from commercial sources which provide highly purified, pharmaceutical grade chemical compounds.
@@ScienceSketch But what commercial sources? A lipid is a fat, right? So, it comes from a living organism such as an animal, plant, or human. So, my question is where are the lipids derived from that are used in the Covid mRNA vaccines? The ingredients list simply says lipids, but that is extremely vague. That would be like saying a food contains fat on the ingredients list instead of stating the actual ingredient that provides the fat.
Hi Jessica, OK, you asked for it! The exact formulations are proprietary. That is, each company has its own “recipe” to make lipid nanoparticles. As part of the application for EUA (emergency use authorization), each company has to disclose to the FDA, the exact formulation that is used in the vaccine. This information is publicly accessible, but you have to hunt for it. I carried out some hunting on your behalf. For the Pfizer/BioNTech vaccine, the ingredients are given in this document:
www.fda.gov/media/144413/download
Section 13 lists “lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg 2[(polyethylene glycol)-2000]- N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-phosphocholine, and 0.2 mg cholesterol).”
Most of these are synthetic lipids. That is, they are made in a laboratory, not isolated from a plant or animal. If I had to guess, the only naturally occurring one is cholesterol which is probably isolated from chicken eggs, and then highly purified. You can look up the other components in google.
@@ScienceSketch thank you so much. I will read the information you provided. Once the vaccines become fully approved will the FDA have the companies be more transparent?
@@ScienceSketch also thank you for taking the time to introduce me to synthetic lipids. I didn't know this existed! I looked it up and learned about synthetic and semi-synthetic. I read that most semi-synthetic are made with soybeans. I plan to search the 4 lipids that Pfizer provides and see if I can find out what type they are. Thank you for giving me a starting point. I am searching this due to severe food allergies within my family. Do you know if there is potential for a lipid derived from a plant or animal to actually produce an allergic reaction, or would the purification process remove the proteins that tend to cause a reaction?
Nano particles , oh hell no !
it’s not the nano is a form of measurement from what i have seen so basically really really small lipid particles
this is from what i found when research i’ll do more but i believe nano means something very small
@@alonnaharris736 it does, but this nanoparticle is a completely synthetic, man made lipid enclosure, for synthetic, man made mRNA.
@@alonnaharris736 Yes, Joyful is right. These are lipid nanoparticles, NLPs, completely synthetic and highly allergenic. They've already been forced to put out warnings that people w/ allergies shouldn't take these frankenvaxes. So much experimental, gene therapy technology, irresponsibly rushed out.
Sainte Jeanne d'Arc True but they’re also saying even if you have allergies take it anyway smh
Can the lipid nanoparticulate piggyback other nanoparticulate , like grapheme oxide ? Dave at 55.
I would love to see you make a video about magnetic nanoparticles used in dna vaccines. I believe this is the reason magnets are sticking to some people's arms. I know the science is real. I've done on people myself on the vaxxed and it works!
What is your opinion on the nano particles being injected? Do you believe they have something to do with the 5G frequency? 🤔
@@electron7659 from what I've read the ionized nanoparticles are use for the delivery of the protein, allowing the body to take it and nor destroy it as it would normally. As far a 5g I have not seen any evidence they are connected.
@@electron7659 people will be chest bursting xenomorphs soon
He doesn't mention the particles as magnetic, so he is either ignorant or concealing information. I think it's the former. It should be shown that these nanoparticles are partly metallic. That is what makes them electric.
Maybe this is how it was supposed to work ,,but does it?
I don't actually understand very well what was said, but, if this tech is truly a solution, why he hasn't there been a vaccine created for HIV deploying this technology?
Can you comment to any extent the effect these Lipid Nanoparticles might have on the Liver? And how they might interact with medications people take (i.e. Acetaminophen, etc)
Hi, great questions... I don't have any information on these topics. I would expect that lipid nanoparticles would be cleared in the lymph nodes (lymphatic system). How much liver exposure there would be is unclear. As far as drug interactions are concerned, based on the mechanism of of action, I would not expect RNA vaccines to inhibit drug metabolism (for example, cytochrome p450 inhibition) so I think it unlikely that there would be a direct interaction on other common medications, but again, I have no data on this question. Thanks for watching!
@@ScienceSketch The particles go to the liver, they are designed for liver treatment, but are working well as vaccines. Arbutus owns the patent to the technology, Moderna is using Arbutus technology without permission.
@@paul1974 that’s probably why my grandma developed cirrhosis after her double shot. She was healthy with no problems, everything tested 2 years ago and now she has 15 diseases. Cirrhosis, Pre diabetes, motor neurone damage, thrombosis literally everywhere. It’s a mess and it looks like hell.
Can anyone tell me what these nanobots nanoparticles are made out of?
The lipid nanoparticles are made out of lipids. You can find the exact ingredients used at FDA.gov. There are no nanobots. No autonomous function at all. The mRNA vaccines triggers the synthesis of a viral protein. Then the nanoparticles are degraded by your body.
The following document shows the components of the lipid layer. Scroll to page 4 to see the chart.
www.cdc.gov/vaccines/covid-19/downloads/pre-vaccination-screening-form.pdf
@@ScienceSketch Hi, thank you for the video, but can you please explain how exactly the nanoparticles are degraded by the body?
Secondly, let's say I have all my ACE-2 receptors blocked/covered, and so the vaccine cannot bind to any of the cells...What would hypothetically then happen to the mRNA-lipidnanopartical package?
Am here before the extinction of real human, genes and DNA...
Best explanation of this I've seen on TH-cam
Thank you very much for you kind comments.
@@ScienceSketch while you explain the LNPs possibly being more “selective” they aren’t there yet. So when people are getting the jabs now, the LNPs and their subsequent mRNA payloads are setting up shop in places like the heart, causing spike proteins to be created in heart cells, causing an immune/inflammatory response in the heart. The whole process is pretty janky. And to that end, since you are only producing 1 type of protein and not a complete protein picture to the immune system, the immune system is still behind the curve, leading it to being extremely “leaky” to the point where it isn’t even a vaccine, it is a therapeutic. As it doesn’t prevent infection or spread, but instead lesses symptoms; a therapeutic.
@@SykoEsquire where can I read more about what you're talking about it's very interesting and helpful
@@UniversalMind-10 I have had to jump all around on the internet, honestly. I want to have as an informed decision on these “vaccines” as possible. There are some videos on here that explain the mechanics very well. Scientific papers are out there to dig up, if you are inclined to read them, you’ll find that LNPs, were designed to have many various rolls, based on their construction. Even as a medicine delivery system, to even help structurally repair heart tissue. Unfortunately, in my opinion, in the rush of development, I believe we got an extremely poor vaccine out of it. Can it improve, absolutely, but I am a skeptical early adopter. I try not to get a first generation anything, like vehicles or electronics, and certainly not medicine, unless the reward outweighs the risk.
The true test will be later on down the road, when I suspect they will want to replace all current traditional vaccines with mRNA types, to maximize production and reduce cost, so they had to get a proof of concept with a largely survivable virus. If they tried this with, lets say, polio, and it failed, this technology would not see the light of day.
For me, until they address the selectivity and fidelity of mRNA to produce antigens, I am not sold.
@@SykoEsquire Thank you! So the lipid nanoparticles can end up carrying mRNA into other places is what your saying?
Ribonucleic sole purpose of existing is to destroy bits of rna.. so once the lipid nanoparticles releases it what stops from still destroying it?? .. help me understand
It doesn’t turn off...
The. Side effects of nanoparticles curing the mRNA of COVID?
Caring the mRNA
I have a question regarding the protein being administered. If the virus mutates, then it will have different proteins, so does the vaccine become in affective?
With the mRNA vaccines, it is actually mRNA that is administered, not the protein. The variants (viral mutations) do affect the efficacy of some of the vaccines. Most of the vaccines appear to be effective against the UK variant B.1.1.7. On the other hand, the Oxford Astra Zeneca, Johnson Johnson, and Novavax vaccines are less effective against the South African variant 501Y.V2. Here's an article for more information:
www.ft.com/content/e9bbd4fe-e6bf-4383-bfd3-be64140a3f36
The virus will continue to mutate as it passes through humans. So the important thing is that we stamp out this virus as quickly as possible using the vaccines that we have.
Will have to get an updated vax every few months for the rest of your life. Enjoy 🤣
@@ScienceSketch bruh still believe this with a virus with ifr of 0.15%😅🤔
it has never been isolated
Yes it has been.
The virus was first isolated in China on Jan 7, 2020 and the genome sequence was published three days later.
www.ncbi.nlm.nih.gov/pmc/articles/PMC7098030/
and
www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/
The lipid nanoparticles are made in lab or are natural? If they are polymers are made in lab , correct?
What happens to the nanoparticles after they deliver the RNA?
Gets shedded out of the body
I’ve read from multiple sources that they accumulate in major organs
@@alltheworldswonders4926 liver most likely considering most of these process happen in the blood vessels.
Do nanoparticles have free access to cells? Is that why moderna is using Nanoparticles to deliver the mRNA into the cell? Question: is a virus itself also considered a nanoparticle? If so then why don’t they have free access into cells but need a lock and key mechanism to enter cells?
Thanks for your great questions. The SARS CoV-2 virus is a lot like a lipid nanoparticle (LNP)-basically a lipid shell with some proteins surrounding an RNA package. LNP’s have free access to cells, and they are brought into cells through a process called endocytosis. The SARS CoV-2 virus uses the spike protein to specifically bind to cells which display the ACE-2 receptor. In that way, the virus directs itself to certain cell types in the human body. The ACE-2 receptor is found in the tissue lining the lung, in the intestinal tract and in other tissues. After binding to the ACE-2 receptor, the virus is brought into the cell as the ACE-2 receptor is pulled into the cell. The LNP’s (to my knowledge) don’t have a specific way to target certain cells over others, although the next generation of them may have the capability to do that.
@@ScienceSketch thank you so much for the excellent explanation. Makes complete sense. I’m so glad I found your channel.
Molecular biology is always very interesting.
Are these lipid nanoparticles the same as magnetic nanoparticles and were they used in both Phizer and Moderna vaccines?
The lipid nanoparticles are used in both the Pfizer and Moderna vaccines, although their composition is slightly different. They are not magnetic.
@@ScienceSketch I guess you know there are videos going around where it shows magnets sticking to people's injection sites. The videos seem to be legit, not faked for whatever reason. I think the very first one that went viral was in the U.K., but a number of reports in the U.S. as well. I've been trying to see if there cannot be some reasonable explanation for it such as magnetic nanoparticles or even things like iron oxide being part of the vaccines. What people are saying is that they believe they're being chipped for tracking!!! To be clear, I do not believe that, but this is going around and I think it needs to be put to rest or proven false. I'm just looking for answers.
When was the virus ever isolated???
Several strains of the virus have been isolated from patients by research groups around the world. The first time that the SARS CoV-2 virus was isolated from a patient and its RNA genome was sequenced was by a research group led by Peng Zhou from the Wuhan Institute of Virology in China. The virus has also been visualized by electron microscopy showing the characteristic spikes.
Visualised ?
@Dr Darren There is a huge number of published covid genomes. You can find them here is you wish to look at them www.ncbi.nlm.nih.gov/datasets/coronavirus/genomes/
@Dr Darren That is a great point. China gave us a computer generated sequence, not the actual isolated virus.
In this video, I seen that it can take years to have a new vaccine for a virus. There is a certain process how RNA works, in how it can attack the virus. I am very amaze in how in our bodies work. I often familiarize this COVID19 virus to the flu. Many of us do not take the flu shot because it has been here for several years, and we do not often hear people dying from the flu because of our lack of knowledge, but we should take knowledge that everyone should put the flu shot as well as the covid shot to decrease further spreading.
If you got the Covid shot, I suggest getting all the updates.
thing is,you dont dont talk about the disadvantages of nanoparticles... neither did you mention the hiv fragments used to enter the nucleus, which covid has
Do you have a science journal or article that explains this further? I would love any sited sources of information. I want to educate others about the dangers of this new mRNA vaccine. Definitely would appreciate it!
@@hurricanehan6073 Anthony Patch , on youtube, has a video called “Retrovirus Retrospective”. He dives deep into detail about covid, its strains, spike proteins and what the future can look forward to considering a vaccine and electroporation.
I couldnt find the source he mentions about the HIV-1 fragments, although he goes very into detail.
Here is one of the sources Anthony Patch uses in his presentation: www.biorxiv.org/content/10.1101/2020.12.12.422516v1
Talks about reverse transcription of Sars-Covid-2 RNA
@@hurricanehan6073 i would highly recommend checking out his channel along with his website and magazine
@Shobah- I have been researching scientific journals, research, animal challenge studies related to human coronaviruses,SARS-CoV, coronavirus therapeutics&potential vaccines and the like since the first mention of SARS-CoV 2. I actually read the past research associated with “Gain of Function” studies done in association with (SARS)coronaviruses and how they utilize HIV
Look under pseudovirus production in this article
academic.oup.com/jid/article/218/2/197/4810771
www.the-scientist.com/the-nutshell/moratorium-on-gain-of-function-research-36564
www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502
Lentiviral and or Lentivirus is HIV-1
www.ncbi.nlm.nih.gov/pmc/articles/PMC1635018/#!po=1.06383
Vector viruses
www.creative-biolabs.com/vaccine/lentivirus-as-vaccine-vectors.htm
@Shobah- Thanks for the information links! Much appreciated
Another link to HIV and CoVid.
www.dr-rath-foundation.org/2020/04/nobel-prize-winning-scientist-who-discovered-hiv-says-coronavirus-was-created-in-laboratory/
He also mentioned Malaria
www.neweurope.eu/article/nobel-winning-scientist-says-covid-19-originated-in-wuhan-lab/
Came here after a Klaus Schwab video 😕
McAfee we need you buddy for virus protection this covid is like a operating system in a computer
Bill gates will help
Half truth.
TEST IT ON ANIMALS before using it on humans?
These particles are quickly becoming the new toxin gambit, like mercury in traditional vaccines. It's easier to make large quantities of RNA than it is to make large quantities of proteins, but I believe they have to be stored at ultralow temperatures using -80°C freezers that cost upwards of $10k. Great job with the video, throughly enjoyed
Pretty spooky
What if the vaccine is not a vaccine
What if your brain is actually an omelet?
Very Good video. Good information
So nice of you to say so. Thanks for watching!
Are we going to live beyond 60??
nah bro, real question is,
Will we even make it to 2030, consciously ?
@@shobah2952 dude you rock. That is an extremely fair question.
Very nice explaination, detailed and understandable. When the antigen is displayed on our own cells where it is recognized by the immune system, I would like to know what will happens as the immune system will start fighting our own cells with this new antigen display on its surface. It might be that the antigen are just release outside the cell, not causing the LT to attack the cells but only the antigen ?
And also if you have time, how does the vaccine target specific cells and will not spread in your body to integrate mRNA in cells like neurons. Thanks :)
Hi Bastronom, thanks for your great questions. As far as the adaptive immune response is concerned, the key to targeting infected cells and not healthy cells is the MHC (major histocompatibility complex). All cells (not only antigen presenting cells) can process foreign proteins (e.g. virus protein) and bind the epitope to MHC1 which are presented on the outside of the cell where they interact with CD8+ T killer cells. But here is the key: endogenous proteins from the host are also degraded and presented as epitopes. The presentation of self-antigens on MHC1 prevents your immune system from targeting your cells. The immune system is astonishingly complex, and I would suggest that you refer to on-line sources for more information. With respect to your second question about the vaccine targeting specific cells...It is known that dendritic cells are covered with lectins that recognize carbohydrates. It has been found that decorating lipid nanoparticles with carbohydrates (e.g. highly mannosylated lipids) can increase the potency of vaccines.
@@ScienceSketch would that also increase the potency of side effects since you still have foreign substances roaming inside of you
@@ScienceSketch are these lipid nanoparticles biological how do they know where to go is it similar to the way a plant would move nutrients from one cell to another or are we talking about microscopic machines that are programed to go where we tell them. I would like to understand how the RNA knows where to go and how its better to let a synthetic strand into a cell rather then a viral one. Any suggested videos or reading would be appreciatedd. Great video @ScienceSketch and great question @Bastronom
@@malcolmmomotiuk7744 Thanks for your questions. The lipid nanoparticles (LNP's) are man-made, not biological and they don't really know where to go. They are not programmed robots or machines. They are absorbed by the body, and are exposed to many tissues and cell types in the body. The cells that are most important for eliciting an immune response are the dendritic cells. The vaccine makers insert a synthetic strand into the LNP which codes for the spike protein. The viral strand would code for the whole virus and cause proliferation of the virus inside the body, and we don't want that! For further reading, I would recommend the two references in the description of the video. Unfortunately, the Future Science paper is not open access so you need to access it through your library or institution. The Nature paper is open access, but doesn't have as much detailed information about mRNA vaccines. Nature Nanotechnology, Vol 15, 2020, 646-655. Insert that citation into your Google search bar, and it will take your there. Also I would recommend Wikipedia for definitions of general terms and explaining immunology concepts.
Sorry the centre is not water
You're talking about micelles. Lipid nanoparticles encapsulate mRNA using an ionizable cationic lipid, the centre is lipid, and the membrane is not a bilayer
Hi Paul, thanks for your comment. Perhaps there is some confusion in terminology? A micelle is a lipid monolayer with a lipophilic center (en.wikipedia.org/wiki/Micelle). A liposome is a bilayer with an aqueous center in which the lipid is primarily a phospholipid. From my primary source which is cited in the description, "Lipid nanoparticles generally consist of an aqueous core surrounded by a lipid bilayer shell that is made of a combination of different lipids." and "Indeed, water-soluble molecules, such as proteins and carbohydrates, can be entrapped within the LNP aqueous core, whereas lipophilic compounds can be incorporated into the LNP lipid bilayer..." From Therapeutic Delivery (2016), 7(5), 319 - 334.
@@ScienceSketch Yes sorry I meant liposomes. The source is incorrect. I am working at a leading mRNA LNP company in formulation and the LNP you are meant to be referring to has a hydrophobic core. I havent read your source but they may be referring to lipid nanoparticles as a class, which includes liposomes and micelles, but are certainly not what the covid vaccines are made from. Try reading Pieter Cullis papers around entrapment of nucleic acids in LNP, there are many papers discussing the structure, the cationic lipid and cholesterol forming a droplet in the centre of a single layer of phospholipid, where mRNA is entrapped due to charge interactions, and PEG stabilizers on the outside.
Thanks for the clarification, Paul, and thanks for sharing your expertise in this area. The review article that I am using for the video (Therapeutic Delivery (2016), 7(5), 319 - 334) concerns lipid nanoparticles specifically for the delivery of mRNA as vaccines. In fact, the title of the review is "mRNA vaccine delivery using lipid nanoparticles." The review article cites papers by Pieter Cullis, a world leader in the field of nucleic acid delivery (primarily mRNA & siRNA) using LNP's. A recent review by Prof Cullis discusses lipid nanoparticles as I have depicted them "size in the range of 100 nm and containing a single bilayer separating the interior aqueous medium from the exterior." Lipid Nanoparticle Systems for Enabling Gene Therapies, Molecular Therapy, Vol. 25(7), 5 July 2017, p. 1467-1475, by Pieter R. Cullis and Michael J. Hope.
There are a variety of formulation technologies that the vaccine companies are using. The specific formulations are proprietary, and not shared publicly. There are going to be patent infringement cases and cross-licensing arrangements that are going to take a while to sort out.
@@ScienceSketch Yes, because Moderna are trying to get away without paying Arbutus for their invention.
Thank you for your fantastic animation & illustration.
Many thanks!
Isn't questionable to ask the cells to produce pseudo viruses and to create Trojan Horse nano particles for their delivery.
A foil hat will protect you.
If millions of years of evolution stops this for a reason then i think its best not bypassing it.
Your video is very nice. Thank you very much. I would like to know the following : When our body is making its own mRNA, which goes outside the nucleus to cytoplasm, this mRNA is not protected by lipid nanoparticle as it is the case in the vaccine. Therefore why doensn't the ribonuclease cause the degradation of the mRNA ?
Hi Zehra, thank you for your kind comments. Great question! As you point out, your endogenous mRNA is not protected by lipid nanoparticles and is subject to degradation by ribonucleases. True! Nevertheless, the mRNA has a sufficiently long half-life to allow the translation of mRNA to protein. Then, at some point, its job is done, and the mRNA is degraded, thus halting the production of protein. It is a carefully controlled and beautifully orchestrated system. There are a lot of factors responsible for the stability of the mRNA in the cytoplasm...too complicated to elaborate in this forum. I would urge you to pursue this question using on-line resources.
Without the lipid nanoparticles (LNPs), the RNA from the vaccine would not even make it to the cell. Even the surface of your skin has ribonucleases. So it is essential that the exogenous RNA be protected with the LNP.
@@ScienceSketch Thank you for your answer. And again, it was a great video !
@@ScienceSketch that is an excellent point, a phenomenally fine tuned system. You know that when DNA is tinkered with, removing faulty genes, upregulating, downregulating and so on, there are unexpected and often catastrophic effects. I am curious if you can see that there might be similar unexpected problems with introducing synthetic mRNA and synthetic lipids into such a fine tuned system?
Absolutely! That's why we do clinical trials. It is only in the trials that, first and foremost, safety can be established and second, efficacy can be established. Safety always comes first. The phase I trials are done very carefully with small, single doses and careful observation, monitoring vital signs and doing blood work. Only when it has proven safe, does it go into more volunteers with multiple doses. In the case of mRNA vaccines, the hypothesis is that because mRNA is so fragile that it will do its job and then be degraded quickly. Only the acquired immunity lasts. One theme that I have noticed in the comments in this forum, is that many people look at SCIENCE as a big monolithic rule book, but in reality science is all about experimentation and observation. Science is empirical. Every drug and vaccine starts out as a testable hypothesis. Only after carrying out the carefully controlled experiment (in this case the safety and efficacy of a vaccine), can a reasonable decision be made to progress.
@@ScienceSketch
I can see that you love science, and that you have great faith in scientists and their desire to do good things for humanity. And I think that is a wonderful, admirable perspective. I love science too, and my children are engineers and mathematicians. We are a STEM family. But as an older person with what we call "the long view" of humanity, i have simply seen far too often that money corrupts and power corrupts. I very strongly disagree with the statement that these trials were done carefully, these vaxxes are a grand experiment being carried out on millions of humans. The people who have died and will die from this vaccine mattered to the ones who love them, just as I am sure that you matter to those who love you. Imagine how they would feel if you took the vaccine and died within hours or days. You aren't a statistic, you are a valuable human being and your life matters, just as their lives mattered too. There is a difference between dying of something and dying from something that was supposed to protect from getting sick. I can see that you have a thirst for knowledge, and that's a wonderful quality. I an going to pray for you, I am going to ask God to show you the truth, to give you knowledge about this matter from God's perspective. I do appreciate your response. God bless you
If this is so then covid19 is the real life Foxdie, Ever played Metal Gear Solid ?
Thank you very much.
You dont want plant or animal rna floating around. But hey manmade viral rna, howdy ho and were in business, everybody should do it.
gmo junk science
Oh my, well this is interesting.
This documentary is a model for all RNA vaccines. From SJM03 VARICAP
Rolling out now.
Full of nanobots
I had 1 in Aug. Did I take the Mark? Bible says right hand or forehead. Lord come fast.
Ivermectin
This is propoganda! 😵😳🤬
Its the mark of the beast. This is what God has warned us from for thousands of years. Many will be deceived, many will perish for a lack of knowledge. Not straight away, but when the wrath comes. Seek God now, jesus is waiting for you, he loves you but you need to deny satan all the way.
dont spread fake belief🤣🤣🤣this is not the mark of beast ok becoz were not yet on tribulation period..
@@암살자-q6y dont be scared little one, the trib is upon us.
No way keep it
Good Explanation thanks
LIES, LIES, LIES. Why have u not pulled this BS down??
Your content is always intriguing 😊💥💥💥
Thank you very much, Shashwat. I appreciate your kind comments.
You go first I'll watch for about 10yrs
Scary millennials what happens to the boomers will it happen again to use when we are their age????
what is happening to boomers that might happen to us?
No = No
great explanation
Thank you very much!
Gonna be a no from me dawg.
Great video!
Glad you enjoyed it.
This is in theory.
Dont do it.... simple as that...
Yes. Please do prove Darwin was right by dying of Covid yourself. Thank you.
En español please.🙏
¡No tome
Nos matan a todos.
Ni loca me la pongo. Q la pongan ellos allí donde no les da el sol. Jiji. Asesinos