Pyruvate dehydrogenase complex

This is a short animated video on the function of Pyruvate dehydrogenase complex. Pyruvate dehydrogenase complex (PDC) is a complex having three enzymes that converts pyruvate into acetyl-CoA by the mechanism of decarboxylation reaction of pyruvate.

[@sevenselevens4951]

literally the cleanest explanation i've seen, great job

[@imamabraham]

i just waisted 29 minutes on a video for decarboxylation of pyruvate and didnt get anything, the greatest explanation in less then 3 minutes... the best.

[@bruhzone]

45 mins of class into 3 minutes may allah bless you and give you all your hearts desires. may you and your loved ones thrive in the earth and in the hereafter. amen

[@mohammedabid6438]

You explained 5 pages of my biochemistry textbook in 2 minutes

[@imamabraham]

yeah man

[@DresdenDoll79]

Great animation. By far the best video I've found that explains this process. Thank you!

[@mojomonger]

finally! something that gets the main ideas down in a clear quick way.

[@mythstapes]

i've literally reseached on the topic for 2 hours straigh and didn't understand a thing; thanks to you i understood that it's a very stupid and basic reaction. thank you SO much

[@imenehk2048]

Wow 2minutes and it’s all clearly explained! Tnxx

[@santelmo5222]

This was a great visual, thank you!

[@SheelamSrujan]

Really it made the concept very very very understanding and easy ....thank you ...❤️

[@richanarayan5166]

This was So quick n easy to learn 👍👍

[@theusualbrownie]

Bro I absolutely love your videos. Thank you!!

[@thaibinhnguyen6333]

A very depictable animation. Thank you^^

[@khatirbehlol1449]

Ths wz tremendous job... For quick overview... N crucial days of preps... Thank uuu

[@waffpcake]

that's fantastic, i understood this so clearly, thank you so much!

[@theprantikdeka]

ome of the best explanation

[@shahlaiqbal3635]

Fantastic explanation 🤗

[@ZeeshanAhmad-yg8pk]

Wonderful work.

[@yukine_it9483]

Thank you for this amazing video! :D

[@jasonmckay1427]

To think it was that easy. Thank you!

[@keerthanakumar8832]

amazing explanation thank you

[@shinn-tyanwu4155]

Excellent presentation 😊

[@fellforfall9802]

very clear, thanks a lot!!

[@XxGameMaster999xX]

the music is so distracting

[@RudebwoyPmask]

Facts

[@OneFreeCoochie]

Such a vibe tho

[@fatimahmakun3455]

Simple and Nice
Thanks a lot

[@prarthana2692]

What a smart explanation...

[@jessicalv6442]

Jesus, this is amazing!!!!!!! Save my life!!!

[@zachreyhelmberger894]

Jesus IS amazing and wants to save your life! Learn for Him with all your heart, with all your soul, and with all your strength and He will bless you and cover you with the feathers of His wings so that no one can ever snatch you away from Him.

[@garimarathor2091]

How do you make acetic acid in the E2 complex?

[@jongelb9603]

At 1:48 I’m pretty sure that the oxidized product of E2 catalyzed process is not acetic acid but a thioester

[@sevenselevens4951]

yeah i think you are right

[@sumanpal8656]

Thank you for such a clear explanation

[@PLANTABYGIA]

Great short explanation

[@nlnrao123]

Simple and superb

[@piyushakadekar5370]

Nice explained

[@joshchronis3750]

Awesome video

[@Indivisible2025]

this was so helpful!

[@medecin6248]

رائع 🌹 بارك الله فيك

[@مودةفوزي-س1م]

Wow amazing

[@shekinah6853]

great stuff!!!!

[@hakob2168]

best explanation

[@himanshitanwar7907]

very helpfull video

[@bublisoniyak6227]

Wonderful!!! ❤

[@susanzhou3866]

wow clear and quick!

[@selcukpolat2371]

Great video,thanks

[@abdulbasitghauri8934]

Why pyruvate directly don't enter to Krebs cycle?

[@robinsondinh2412]

It has to be converted into acetyl coA so that it can combine with oxaloacetate and form citrate

[@nandinithakur20]

Was this topic that easy? Man i read it for an hour and I didn't get a thing and u just took 2 mins.... Now even if i try I won't forget this😂

[@saaabji7083]

Can somebody explain why E1 is called dehydrogenase when it carries out the decarboxylation reaction?

[@parijat7526]

Because also catalyzes the oxidation/dehydrogenation of Hydroxymethyl group of Hydroxymethyl-TPP to Acetyl group

[@ethanbaird5058]

this is great

[@lolitsme6]

thank you so much 💙

[@ammarali1914]

Great job! Kuddos to creators

[@abdulazizalghanim6437]

thank u sir, you saved me

[@NehaKhan-zf1nk]

Thank you 🤗🤗

[@kindaalzouabi6845]

thank you❤❤❤❤❤❤❤❤

[@drsirisha2918]

Well explained

[@nishantthakur6896]

BRO please tell the mechanism too ..

[@georgette9203]

thank you

[@Jatinmamgai]

Thank you so much

[@dontrock]

thaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaank uu

[@miloshalda2031]

cool

[@janvisharma2048]

😀😀❤️❤️

[@Winter_____]

👏👏👏

[@lauramarchisella9502]

great

[@arielleaiken]

i love the music

[@thisunudagedara2266]

goated

[@mbbslovers9572]

Nice explained but , I think E1 is pyruvate Decarboxylase not dehydrogenase .

[@sevenselevens4951]

no it's dehydrogenase

[@a-b-f3403]

10x man

[@shahimtajulhaque9786]

All explanations are uulala, but don't mind why you try to change your accent 😟

[@Chickennuggetandfries]

good video but i hate the music

[@오즈만디아스]

nice pronounciation

[@awanier786]

E1 is pyruvate decarboxylase + thymine pyrophosphate not pyruvate dehydrogenase

[@12deimos]

It is called p decarboxylase or p dehydrogenase, those are synonyms.

[@m0ony1]

Dr Majid Awan They’re synonyms so both are right pyruvate dehydrogenase (decarboxylase) complex

[@Sveccha93]

*thiamine

[@RedHeadSH0T]

Music is horrible

[@-_-_-_-_-_-_-_-_-_-_-_-...]

vurrryyyyyy gud! (indian accent)

[@Botanophilist]

Thank you so much