The Basal Ganglia - Direct and Indirect Pathways
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- เผยแพร่เมื่อ 29 พ.ค. 2024
- An overview of the basal ganglia and the direct and indirect pathways model, as well as how this applies to Parkinson's disease and Huntington's disease as well as their potential treatments.
![[UNCUT] รัฐสั่งหยุดปล่อยคลื่น! แต่หยุดพลังปะทุ “น้องหญิง” ไม่ได้ I คนดังนั่งเคลียร์](http://i.ytimg.com/vi/RmQh47eIiV0/mqdefault.jpg)
I was dying to learn this , NOW I'm crying because of your video . T-H-A-N-K Y-O-U
This has helped me so much to prepare for my exam, thank you!! So clear and simple visuals.
One of the best explanation video about basal ganglia I have seen in TH-cam till date....simple, clear, concise, descriptive.
It especially gives confident for the viewers that they gained some knowledge about basal ganglia without confusions...keep it up✌✌
Another awesome video! Please continue making more
These are some of the best neuroscience videos on youtube. Good speed, through explanation, and EXACTLY the proper amount of depth for someone studying. Many videos are too "overview" or too stuck in the minutiae. Please make one about neuroanatomy of attention!
This helped me out so much. So easy to understand. Thankyou!
perfect video. helped me learn very quickly. thank you!
At the end of serching a lot ,I clear my concept from here.Really helpfull ,keep sharing such Vedic.
This explanation is tooo good! Thank you soo much!
Thank you so much . This video is so helpful !!
Thank you so much ...i havn't understand this from any other video ...but thanks to you i have grasp it better now..
excellent, learned this very well in 10 mins
This is gold!! Thank you for uploading this
Best video I've seen on this. Thank you!!!
The explanation simple, easy and awesome. Thank you soo much
Nicely explained!! I used it for quick short review .. thanks
honestly, that was so helpful
finally i undertood it, Thank you so much
blooody awesme mate!!!! that was a trademark 007 description! keep it up! i m ur subscriber from now on
amazing video! highly comprehensive! :) thankyou!
This is incredible - thanks so much!
This video is very helpful. Thank you !
Thanks, this is the best explanation I've seen!
Trust me, this is the best explanation available here in youtube, sime. easy. concise.
Great explanation. Thank you so much 🙏🏼
Thank you so much for clearing it out ! I found it very useful
Thank you very much! This helped me a lot :)
smarty summarized n superbly described :) thank you
great video!!! amazing explanation.
This video is simply awesome. I have looped it for over 10 times every time I need to review the pathophysiology of Parkinson's disease. Thanks!
This is amazing! Thank you so much!
Very clear explanation and drawings!
Thank you soooo much
I have seminar tomorrow n this was the best way to learn, and guess what i liked it, as it was v interesting.
Thank you so much! Your clear, quick and concise explanation finally helped me realise how the dopaminergic modulation by the SNc was connected to the direct and indirect pathways. This has been a big help
Thank you so so much! Cannot explain the satisfaction from finally getting the direct and indirect pathways. I watched a couple of other videos, but yours is by far the best explained.
Thank you. You SAVED OUR LIVES U DA BEST!
thank you so much!!! this is very well explained!
thank you so much. this was really helpful!
A big thank you, simply amazing
Excellently explained
This is honestly the best explanation I've seen! Thank you :)
Absolutely brilliant! You're awesome!! :D
This. Helps. So. F. Much.
I'm shocked.
omg I'm still speechless. this helps a lot. Like,, a LOT. No i have a better understanding with direct and indirect pathway, i cant thank you enough for this, but thank you very much🙏
Most concise and most valuable video on TH-cam for basal ganglia, thanks!
quick and simple!
Thank you so much. It was so helpful.
Beautifully explained 👍👍
This is like GOD sent me this video 😭. What exactly i was looking for
This is great, best explanation so far. I hope you continue making videos!
This video is amazing. Thanks
I finally understood pathways after a very long time!
Thank you
Excellent
Keep making more !!!
OMG! I love this... best explanation so far... with pathology of 2 diseases... but how about hemiballismus?
You made it easier thank you 🌹
awesome really appreciate it
thank you
Excellent explanation
Loved it ...I wasted 2 hrs studying this...learnt in few minutes
this help me a lot. thank you 😭💕
Great work....keep it up...👍👍
Amazing 🙏🏻 thank you 💘
Nice and clear. Thank you
amazing! thank you !!!!!
excellent video!
Bless your soul
Thank you so much!
Very helpful to learn for USMLE
Great job. Very succinct in less than 10 minutes. Very useful for my USMLE
best video ever. thank you.
Great help!
Great video and I hate to bring this up but isn't ganglia a term reserved for grouped nuclei outside of the CNS?
It's such an amazing explanation!!! I saw many video about these pathways before but just this... is the best version I've seen. Thanks you so much
Thank you!
thank you so much
Awesome! Thanks!
helped a lot! thanks!
This video z amazing...thnks
Brilliant.
thank u sooooo muchhh . deserves 10 milloin likes
This helped alot, thx!
Absolutely amazing! Really well explained :)
Thank you, this helped a lot! Could you comment on the role of acetylcholine on the basal ganglia? Antipsychotics block dopamine-receptors in the striatum causing parkinsonism. Anticholinergics release these symptoms (at least partially). How do the acetylcholine-neurons integrate in this model?
I am prescribed Procyclidine, it is an anticholinergic, a great drug which acts on the acetylcholine system of the brain. I know that acetylcholine is an important neurotransmitter, the effect of this drug is not only alleviation of any side effects but also a really good boost in mood especially if the person taking it were really depressed. It's not used in the NHS or in the world as an anti-depressant but I think it's a really good chemical and would be perfect for cheering people up who were feeling sad, or feeling demotivated. It's not safe to overdose, it's non addictive when taken at safe dosages I have found myself, I take a dose of 10mgs a day and then, even if life can be depressing, I am still reasonably happy. Not all of the anticholinergic drugs boost mood, but Procyclidine seems to do it quickly and very effectively.
the best! thanks !
Amazing!
Really good explanation of the topic, cleared up a lot of confusion on the topic for me!
great video
Very well explained; concise yet comprehensive. Thanks a lot
This was really great revision, thank you!
When we are considering an indirect pathway without the involvement of DA, the cortex is exciting the Striatum and following on from here we will eventually get to inhibition of the Cortex =withold movement. However, using the D2R in the Striatum, you start by inhibited the Straitum so, shouldn't the final outcome be opposite of excitation of Stratum i.e you end up exciting the cortex = movement initiated for the Indirect direct pathway involving D2R. Can you explain this?
You finally solved my problem in this part after a long time ago. Really appreciated that!
this video is amazing ily
My Globus Palidus has exploded after watching this video. Good work 👍
Thank you so much
:)
You're awesome !
thanks so much
That's spot on! Great supplementary video to my lecture material that I was studying
Hi do you have any references or places where you got all of your info from?
C H well for all information from standard textbooks.. you need to check out physiologyopen: Basal ganglia physiology | Connections and functions | Direct & Indirect Pathways |Movement disorder th-cam.com/video/oQYY84JTak4/w-d-xo.html
You good sir have helped me so much! Thank you for creating this video. Liked and Subscribed!
Superb ...
amazing amazing amazing!
Best video ever
I loved neuromedicine just by watching this video...thank you
Amazing! Never seen such a good explanation ! Bravo