Vitamin D and Autoimmune Disease
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- เผยแพร่เมื่อ 7 ก.ย. 2024
- Vitamin D and Autoimmune Disease
25871 participants, consisting of 12786 men ≥50 years and 13085 women ≥55 years at enrollment.
Eligible participants, recruited throughout the US, were required to limit vitamin D use from outside sources to no more than 800 IU/day, and to forgo the use of fish oil supplements.
4 subgroups
1. Omega 3 Placebo/Vitamin D Placebo
2. Omega 3 Placebo/Vitamin D Active
3. Omega 3 Active/Vitamin D Active
4. Omega 3 Active/Vitamin D Placebo
Vitamin D supplementation for five years, with or without omega 3 fatty acids, reduced autoimmune disease by 22%, while omega 3 fatty acid supplementation with or without vitamin D reduced the autoimmune disease rate by 15% (not statistically significant).
Here is the link to the study
This study of more than 25000 older adults in the US provides evidence that daily supplementation with 2000 IU/day vitamin D or a combination of vitamin D and omega 3 fatty acids for five years reduces autoimmune disease incidence, with more pronounced effects found after two years of supplementation.
Vitamin D receptors are found at high density on dendritic cells, T and B lymphocytes and macrophages, whose functions are dramatically affected by activated 1,25-dihydroxyvitamin D binding
Cholecalciferol (D3) 2000 IU/day---Placebo soybean oil
Marine omega 3 fatty acid 1000mg containing EPA 460, DHA 380--Placebo olive oil
Fish oil source Pronova BioPharma the maker of Lovava(Ethyl Ester form)
Vit D source Pharmavite LLC-Maker of Nature Made
Link to the research article
www.bmj.com/co...
Dr. Jin Sung is a Chiropractic Physician who specializes in the management of complex chronic conditions in Massachusetts, 30 minutes north of Boston. He utilizes natural and alternative therapies to help manage complex cases such as Hashimoto's, autoimmune conditions, IBS, SIBO, chronic fatigue, brain fog, early Alzheimer's, etc.
www.DrJinSung.com
/ drjinwsung
Office Contact
978 688-6999
www.DrJinSung.com
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SEARCH on Dr. Sung's Online Store--us.fullscript....
Vitamin D3+K2
Dr. Sung's Online Supplement Dispensary-conditions apply. Certain companies will require a prescription from Dr. Sung.
The content of this video is for educational purposes only and does not constitute medical advice. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.
Link to the research article
www.bmj.com/content/bmj/376/bmj-2021-066452.full.pdf
Other Vitamin D videos
When not to take Vitamin D th-cam.com/video/PboG6rrA-jc/w-d-xo.html
Vitamin D and magnesium th-cam.com/video/I5rcDkYthUY/w-d-xo.html
Truth about vitamin D th-cam.com/video/6E9xfwyX6mQ/w-d-xo.html
Vitamin D and waist circumference th-cam.com/video/TFNUBM_7o_w/w-d-xo.html
Vitamin D and toxicity th-cam.com/video/gFYMs94mx4E/w-d-xo.html
Hello Docter I am from the UK England I watch a lot of your TH-camrs they are the best a question I’d like to ask you can I take supplements of Ashwagandha. Along with lever thyroxine for underactive thyroid 100 MG. two days a week. 75 mg. five days a week I would be grateful if you could get back to me thank you. ❤️🙏
Hi Doctor, you made reference to those who had had their Gall Bladder removed and absorbing vitamins, could you do a video on that and what to do to help us absorb those vitamins our bodies won't due to no longer having a Gall Bladder, thank you.
Great video! I think a new study with your recommendations should definitely take place. I was diagnosed at 30 years old with hashimotos, and I suffered for 20 years before I found a medical practitioner who was willing to listen to me instead of blame me. She helped me with my diet, my hormones, my thyroid meds, and supplementing correctly. Now I am finally in remission after decades of agony. Dr. Jin, I hope you can get that new study going because I think it could help untold numbers of people. 🙏
I had one of the worst cases of lupus my doctor saw in 5 years. I started taking vitamin d I got my vitamin d up to 256 my rumotologist said this was toxic level but somehow I was in remission with my lupus at this point which seemed like a miracle. She said stop taking your vitamin d few month later lupus was back and I crashed harder then ever. I recently starting taking higher dosage of vitamin again so far feel a bit better and learned that it will not be toxic as long as you have vitamin k with it.
How many ius per day of vitamin d were you taking when you got your level up to 256?
vitamin k2 to be exact
The generally accepted formula is 100n of Vit k per 10.000 of Vit d- 2000iu is NOTHING!! 100ng is optimal. The formula is 100ng minus your current range x 35x your weight- that is the bolus on the average age person to get to 100. It can be a one time dose!!! Or I spread mine over 4 days. I’m 72 at 10ng. And had suffered freezing m Hashinoto thyroid disease for 35 years- at 100ng it disappeared
I am a 59 yo woman diagnosed with Sjogren's, RA, Lupus in 2012. Innumerable RA's and fast forward to 2019 when I started with an integrative and functional practitioner. I have been paleo since then, as well as ALL THE SUPPLEMENTS YOU OUTLINED in this video. I get my vit d tested every 4 months and all the bloodwork every 6 months. With the added benefit of LDN 4.5 mg as well as bioavailabile hormones... All my autoimmune is in remission.
what is the biovaliable hormones
Bioavailable hormones? Can you explain please?
@@elbshmohanesdexter8052 Chemically identical to the hormones in your body. I take it sublingually. It can also be taken through the skin in a lotion form. I get tested every 4 months to monitor. Since hormones naturally fluctuate this daily dosage allows me to "read" my body. I've learned that sometimes, I need to skip the testosterone or estrogen. Chin hairs start popping up? Back off the testosterone. Breasts feel sore? Back off the Estrogen. I also supplement DIM (Diindolymethane) and Calcium D-Glucarate to detox excess hormones on the daily. It's a lot of work and a learning curve since it's necessary to pay attention and have frequent blood work to understand your body's signals to hormone fluctuations. Supplementation of even bioavailable hormones is not without risk.
Nice. Don’t forget that D3 makes proteins that must use K to carboxylate so supplement with K2 Mk-7, and D3 uses the same receptor on the nuclear membrane as retinal(retinoic acid-vitamin A)- the retinoic acid receptor, so vitamin A is also very import otherwise K can become depleted as D3 will make too many proteins in the nucleus. Balance D3 with A and add K2.
Spot on, also the ratio of A to D3 is 2:1.
@@joeballs1774 do you have a link? Is this oral supplement intake or measured blood level? D2 is usually measured unfortunately as opposed to active D3.
I think you are spot on. I got RA as 2 yearsold, and got some kind of vitamin as 12 years old that made me well. After the first child I got terrible sick and had 30 awful years, and now at age 70 (soon) I am healthier than ever!
Strong as a horse, ( had 3 lung cancer operations and 1 prosthetic shoulder) with 5000 I U vitamin D 3 a day!
Hurrah!
So glad you are healthy again! As someone who got obese, ↑BP, arthritic, severely depressed and finally pre-diabetic after being Rx'd a D-depleting carbamazepine the last 25 years, a new doc finally ordered a D bloodtest that found me at a dangerously low 6ng/ml! She Rx'd standard preloading D2, then 5,000IU D3.
But my obesity needed far more! I was taking 20,000IU/day that finally got me Replete >50ng/ml or 125nmol/L!
Get a blood test, please. Perhaps seasonally twice a year. As we age, we lose the ability to make it under the best of circumstances in high Summer.
ThinElder Fauci, (as we were massively dying from Covid), quietly maintained his own Replete D level!
6,000IU/day in Summer
8,000IU/day in Winter
If you are heavier you'd likely need more.
What a great Channel I always learn something from your videos. You have a balanced approach which is admirable. Thank you.
Have you considered uploading just the audio from your videos to a podcast? I’d love to listen while I drive.
absolutely brilliant ---again ... Thankyou !!!
Superb video!
Your summary analysis is right on 🎯
Thanks again for sharing your knowledge.
Peace and blessings 🙏
I’m taking 10,000 ui vit d3 and k2
And 40,000 before bed as recommended by Dr. Etc I change dosage as needed. No more pains and feel fab! Another dr said 10,000iu was a good starting point indeed.
Your taking 50,000 IU's of vit d3 per day?
You know, dosage isn't what matters. Blood level is all that counts. That's why most studies are next to useless!
Most doctors don't understand that.
Yet.
Just base your dosage on what you/enlightened doctor thinks 'you' need to reach your target level.
Retest often while getting to level, then seasonally 2×/year to maintain as our bodies make less & less as our years rise.❤
@@weich1q2w 50,000IUs is only 125mg - do the conversion from high school
@@KJB0001 mcg
🙏 I look forward to meeting with you Monday morning fresh start for my journey back to good health🙏
I have not been able to raise my Vit D even on high prescribed doses, plus I was recently diagnosed with Graves. The females in my family have the same issues, but we were all misdiagnosed with anxiety. I have high monocytes too
I appreciate you brother. I will spread the information to others
I have been taking Carlson's Cod Liver Oil from Norway for 50 years...it come in a glass bottle and I do keep it in the refrigerator. I does not seem to ever be rancid. I won't take cod liver oil capsules since they tend to be rancid. I seem to be pretty healthy, so I guess it works.
My wife and I have been taking the same Carlsons brand Cod oil for 8 years.
We are very healthy for our age group.
As well , having taken the cod liver oil, I saw significant improvements in my skin and joints ❤❤
What Glutathione supplement would you recommend for a female whose lived with MS and Psoriasis for 30+ years? My D level is 70s. I've keep that u po with D3 5000 IU daily alongside K2.
Good looking dr. How do you stay so fit?? You look great
Very good information. Thank you.
Just stumbled across your channel. So happy I did! Good info!
Welcome aboard!
I take 5,000 iu daily of liquid d3 and i find it helps my fibromyalgia and b complex
Your B complex is synthetic and bad for long term health. Try beef liver capsules instead... AM is preferred because it can boost energy.
Video on boron?
Thanks for the info. I love your channel.
However, I think the conclusions as you write it are very confusing. If the first statement says. Vitamin D WITH OR WITHOUT Omega supplementation reduced autoimmune disease by 22% and the second says Omega WITH OUR WITHOUT D supplementation reduced autoimmune disease by 15%....Each example has an instance of Vitamin D AND Omega supplementation. So...how can the percentages differ when they are both the same condition? (BOTH Vitamin D and Omega supplementation). Please clarify.
I take glycine, flush niacin, taurine, nalc,selenium, nac, msm, zinc for glutathione and vitamin d3 40,000ui, vitamin k2 MK4, omegas(emu oil) vitamin k2 Mk7 600mg, vitamin b2 and magnesium for coimbra protocol and my ra, hasimotos amd eds is reversing.
I too reversed 35 years of Hashimoto with mega vit d and k2 mag- I also needed some iodine so I take 50mg of Ludols 5% daily- NO meds!! Really angry this went on so long unnecessarily!! And only T3 ever helped me!! Now my thyroid works perfect
Mine reversed in literally 15 days and normalized in 30
It would help so much if you used a pointer instead of standing in front of the chart
Exactly
What does it do on lymphocytes count when drawing blood
Could you recommend where to purchase triglycerides form
Can you do a video for stomach ulcer. Love to hear your opinion and how to treat it naturally.
Look up "Dr. Berg" on youtube I bet he has a vide on it
Mastic Gum supplements are used by Naturopaths. Mastic is a milky resin tapped from Chicle trees in Greece. Also, the trace element Bismuth (which is in Pepto Bismuth. Just Google "Mastic for ulcers" to read up on it.
Cabbage juice
Check for Helicobacter.
You said 200 iu initially which is an error - it was 2000
Hi Dr Sung, my husband and I follow your videos all the time since covid two years ago! My question to you is, my husband is autoimmune with psoriasis. I’ve been giving him 4000 IU vit D with K2, zinc and NAC but we’ve not seen any improvement in his skin flare ups. Health wise we’ve been taking them for post covid protocol and prevention of reinfection. Should my husband be taking higher doses of both vitamin D and NAC to help with his psoriatic flare ups?
Are you doing the foundational stuff? Dietary? Suggest AIP diet
2 years ago, I had long term, (about a year), itchy rash all over. Not medically diagnosed as psoriasis, (I don't consult Doctors unless necessary), but very similar symptoms. Came across a Dr Berg vid that suggested L-Glutamine to help heal leaky gut that may be allowing toxins into the body that manifests as skin irritation. 3 months of a tablespoon in a large glass of water on empty stomach daily and the itching went away. I was also taking D3 , K2 and Cod Liver Oil, low carb diet. I have seen negative comments about long term use of L-Glutamine- just so that you are aware. This is just my experience.
Vit D can worsen it - pubmed.ncbi.nlm.nih.gov/19758226/
Can bullous pemphigus be treated with Vitamin D3
I dont understand. I have an autoimmune disease thats causing brain fatigue, depression and anxiety which I am on disability for. The only thing thats helped has been vitamin D on a dose of 5000Ius a day. But when my doctor saw my level was at 242nml/l she ordered me off it and one month later my symptoms were back. Im now at 140nml and feel soooo badly! Its anxiety, depression and brain fatigue all over again and I am considering suicide 24/7. I cant be at 242nml which is where I felt great because the doctor says its toxiv but at 140 I feel like Im dying so what do I do? (And yes, I am off dairy and gluten since 6 years)
Get back to you levels of d, doctors are taught to speak like this , make sure you take k and magnesium and vitamin a and vitamin c.
Instead of described in very detail ,please give in nutshell 😊
@Dr.Jin W. Sung is it true that Vitamin D can cause high cholesterol? I take one spray of vitamin d3 1000iu with k and one capsule of vitamin d3 1000iu only, is this enough? My vitamin d levels last were 80, taking it as diagnosed with autoimmune. Thank you in advance
high choloesterol is antiquated idea It's the particle size that matters- statins cause dementia Vit D can worsen autoimmune like GA, pubmed.ncbi.nlm.nih.gov/19758226/
You stated 200IU but is wrote 2000IU?!
My dr found 3 antibodies for different AI diseases. I did AIP elimination diet. If i dont have any issues with gluten should i still avoid it to help my autoimmune issues? I react to dairy so i avoid it, but gluten seems fine, juts not sure if it is not safest to avoid gluten too.
Hi i have hashimotos and CFS . What about omega 3 coming from marine plants like " Sea buckthorn oil" which also includes omega 7. would it be more bioavailable ? for people with MTHFR or digestion issues.?
Hi could u do a video on eczema and other skin issues plz? Is it to do with the liver? Also constructive negative feedback, clapping at the start of the vid pops my ears with earphones in :(
I am not a medic but my understanding is that reducing inflammation in the body by eating mainly plant foods has a big impact on developing auto immunity. I also believe that vitamin D has a role to play in immune regulation. Perhaps a whole food plant based diet plus vitamin Vit D supplementation would be worthy of study.
I have Crohn's, being a vegetarian absolutely did not work. I will never try again.
@@sunrae7680 I am sorry to hear that a vegetarian diet didn't help you with Crohns. Before I was diagnosed with Ulcerative Colitis I ate very little meat but I consumed a lot of cheese, milk and eggs. I learned that all animal products were inflammatory including dairy so I decided to replace these foods with vegan cheese, plant milks and soya yogurts and I stopped eating eggs. This may be something you could try and I wish you well.
@@helenhucker346bro you prolly went from eating packaged dirty food from bad sources, milk/meat from cow that was fed by grains only, to a cleaner diet, so no wonder that removing dairy from your diet did help you. But being vegan long term isnt healthy, meat isnt inflammatory unless it comes from an animal that has suffered its whole life and eating bad stuff like gmo pesticide grains and who were themselves sick and shot with antibiotics...
Plus soy can worsen autoimmunity in some people and completely made up vegan products are expensive for nothing and usually made of soy or grain...
@@sunrae7680 carnivore is the answer
Would D3K2 be helpful for Granuloma Annulare? And Omega 3 supps too?
If you get your D between 70-80ng/ml (or175-200nmol/L) you can allow your microbiome to reconstruct itself (eat lots of pre & probiotics to help a bit.)
Once there, your N-REM DeepSleep paralysis can return, allowing your body to repair many long-broken bits. Perhaps also your Granuloma?
It let me repair my debilitating PeripheralNeuropathy within 2 weeks!
Watch any of amazing Neurologist/SleepSpecialist Dr. Stasha Gominak's extensive interviews to find out a few more details. She also sells a workbook to guide the process, but I couldn't afford that, did it with some success on my own.
Mk7, Mg, others are always helpful on the 'D Power Team'! K2 is highly protective of our hearts, can also get it with naturally fermented foods, kefir and especiy "natto" which I believe is why Japanese live so much longer than us!🤗
[Natto is specially fermented soy beans & looks totally disgusting. I think the only company making it to sell in the US is very near my home in tiny Sebastopol, CA. You can also buy nattokinase enzymes if you can't manage natto's sliminess! LMAO]
Also try some autophagy fasts! Longer fasting ≥2 days resets a lot of our systems and clears out many pre/cancers & misfolded proteins. Autophagy is what you are after. And yes, high D does make it much easier to do!
But start way less, just pushing back breakfast 15minutes at a time, expanding your fasting window very slowly to make it far easier. Also, cutting out carbs (like in low carb/high fat LCHF/Keto) can cut the addictiveness of food to make longer fasts also beautifully mind-clearing & energizing😁😘
@@eliseville thanks, I do water fasts for 5 every 6 to 8weeks and I IF with OMAD every day that I'm refeeding Doesn't help GA
@@KJB0001 Only a couple weeks ago, I watched a @LowCarbDownUnder symposium response by highest acclaimed Keto cardiology scientist, Dr. Stephen(?) Phinney. He was responding to Dr. Fung’s recommendations for longer fasts with strongest caution because every single study shows a permanent decrease in metabolism rate for anything over 48 hours!
So, since I made my previous comment, I’ve decided to do more 48 hour fasts and skip anything longer to protect my fat-burning capacity. I hoped Dr. Fung would make some effective counter, but I haven’t seen any, so far.💔
@@KJB0001 I was not so much giving fasting credit for fixing gut issues, but a specific, fairly high HORMONE D BLOOD LEVEL! Amazing Neurologist/SleepSpecialist/accidental gut doc, Dr. Stasha Gominadiscovered, despite her PHARMA CONDITIONING, that hormone D both controls the proper paralysis switch (for our deepest & reparative N-REM DeltaWave sleep cycles) AND protects our rebuilding healthy microbiome. Those two conditions allow for miraculous-seeming repairs from even decades ago! (She also recommends a temporary B-Complex while our repair system tries to catch-up quicker than our microbiome can supply our critical metabolites.)
Please, set aside some time to watch any of her fascinating & informative interviews. She is getting excellent results with her young, sleepless patients, AND they all also have a variety of gut issues that have cleared up with this simplest of treatments!
Dr Jin W. Sung! Video at 1:06 - In the study, the maximum intake of vitamin D from natural food sources was 800 IU/day, not 800mg/day.
Oh, yes. 800 IU not 800mg. Thanks for catching that.
❤❤
Please don't clap like you did at the beginning. I jumped when it happened. Unpleasant.
it's Korean, travel, learn something Stupid Americans -Unpleasant
So while all of these videos are helpful to a certain extent. Why has there been a rush of Chiropractic Doctors offering medical advice all of a sudden on this platform.. I am NOT trying to pick on you, Dr. Sung.. There's a ton of you in here(TH-cam) offering free advice which has nothing or almost nothing to do with chiropractic care. Interesting to say the least...
Regular doctors are far more captured by PHARMA! Chiropractors have some of the training, but since they aren't drug prescribers, PHARMA sorta ignores them, letting them spill all sorts of health truth that gets accredited doctors' licenses cancelled in today's censorship regime!
I'm just thankful.😘
@@eliseville Of course, I too, get that. And anything which steers away from Pharma and their lining pockets of the Governmental agencies, the better.
@@Kiss__Kiss Wouldn't it just be nice if well-trained doctors could all be free of PHARMA control? There's several brave doctors that have all had licenses or hospital privileges revoked for trying to treat their patients in ways that don't profit enough.
Dr. Meryl Nass managed to Rx her sick patient Ivm, among other treatments, but knowing how propagandized her pharmacy options were, actually lied about the condition being treated, and the board jumped on her, along with a suspension, is now ordering her to get a psychiatric evaluation, so blocking her from moving to another state! Also those FLCCC docs at the top of their fields are closed out from actually serving their patients, even forced to sit helplessly by as PHARMA's only allowed options fail and their patients die!
If your talking to scholars, ok ! but to the average Joe this isn't of any value