Incase someone wanted a brief summary of functions, Functions of the following components: Collagen - Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and skin. Along with elastin and soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. Proteoglycan - Provides hydration and swelling pressure to the tissue enabling it to withstand compressional forces. Lamina - Laminins also provide adjacent cells with a mechanical scaffold and biological information either directly by interacting with cell surface components. Fibronectin - Cellular fibronectin is assembled into the extracellular matrix, an insoluble network that separates and supports the organs and tissues of an organism. Fibronectin plays a crucial role in wound healing.
wow. you are amazing sir. you are moving at a very well pace and audible enough. everything you say is just so clear and simple. I need more of your videos.
There's some confusion here with what constitutes a GAG and a proteoglycan. GAGs (shown here as red lines) complex with core proteins (black line) to make proteoglycans (erroneous labeled here as a GAG). These proteoglycans can then complex with an HA backbone to make a superstructure. Also important to note that HA is in fact a GAG within itself, that is unique among the GAGs in that it does not complex with proteins directly to form a proteoglycan, but rather, serves as a foundation for other proteoglycans to be complexed with it via serine residues.
I thought the lamina are the intermediate filaments found in between chromosomes and the nuclear envelope and helps give the envelope structure. Then the laminin are the multi-adhesive matrix proteins that cause the cross linkage to collagens and Proteoglycans.
There are a number of different biological constructs called "lamina" - anything that forms a layer is basically a lamina. Laminin happens to be a lamina associated protein.
good efforts sir! you explain and draw very good ,only you should need to focus on arrangement and planning of your lecture ,you were forgetting some points of collagen and were adding it later on......otherwise you teach excellent !!!
Incase someone wanted a brief summary of functions,
Functions of the following components:
Collagen - Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and skin. Along with elastin and soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging.
Proteoglycan - Provides hydration and swelling pressure to the tissue enabling it to withstand compressional forces.
Lamina - Laminins also provide adjacent cells with a mechanical scaffold and biological information either directly by interacting with cell surface components.
Fibronectin - Cellular fibronectin is assembled into the extracellular matrix, an insoluble network that separates and supports the organs and tissues of an organism. Fibronectin plays a crucial role in wound healing.
Thanks dude!
Thank you I really needed this
I've spent hours trying to understand all of this and then I saw your video
THANKS YOU SAVIOUR
wow. you are amazing sir. you are moving at a very well pace and audible enough. everything you say is just so clear and simple. I need more of your videos.
you can bet your bottom dollar
thank you, its clear for me now :) would be nice if you explained elastin too!
There's some confusion here with what constitutes a GAG and a proteoglycan. GAGs (shown here as red lines) complex with core proteins (black line) to make proteoglycans (erroneous labeled here as a GAG). These proteoglycans can then complex with an HA backbone to make a superstructure. Also important to note that HA is in fact a GAG within itself, that is unique among the GAGs in that it does not complex with proteins directly to form a proteoglycan, but rather, serves as a foundation for other proteoglycans to be complexed with it via serine residues.
Your little comments about the whiteboard and accidentally crossing out movement makes this lecture more enjoyable, thank you for the clear lecture!
Probably the best video I found on this topic
Bravo! una bella lezione - mi hai fatto capire olte cose su ECM
Please keep going and thanks a lot for your hard work … you are so helpful .. dean tell you enough
This video was very helpful! GRACIAS, Greetings from Colombia😊
Ow yeah! Great explanation! Thank you very much man.
I thought the lamina are the intermediate filaments found in between chromosomes and the nuclear envelope and helps give the envelope structure. Then the laminin are the multi-adhesive matrix proteins that cause the cross linkage to collagens and Proteoglycans.
Yeah, I think you're right
you are correct. I believe he meant to write laminin, which is most definitely not the same as lamina.
he meant laminin.
There are a number of different biological constructs called "lamina" - anything that forms a layer is basically a lamina. Laminin happens to be a lamina associated protein.
You're good at explaining. Thanks.
Awesome videos! I'm reviewing for a grad level cumulative cell biology exam and these are helpful!
Thank you very much man, simple and easy.
Great❤ what happened to u why aren’t u upload more videos؟
Great video! thank you man you made it simple and easy to understand
Wow, brilliant.
good efforts sir!
you explain and draw very good ,only you should need to focus on arrangement and planning of your lecture ,you were forgetting some points of collagen and were adding it later on......otherwise you teach excellent !!!
It was great but please explain elastin too.
Thanks :)
Great
Thank you so much! God bless you :)
Brilliant and very informative thank you
Thanks alot sir...the lecture was simple and excellent..
Tnqq so much, keep up the good work
👍👍 be success
finally i understand this part, thank you :D
Well explained
thanks, very clear and helpful :)
Thank you so much
THANK YOUU I LOVE YOU
sir please give a class on extracellular matrix of animal
Thank youuuuuuuuu
thanks you .
Someone has exams tomorrow 😂😂
Yup😂
That helped, thanks :)
thanks that was helpful
Wtf is a trimer lol?
come for the fibronectin, stay for the cute boy
😂
helpful :) thnks
Hindi language video please
Thankssssss
It's Laminin, not lamina.
Thank you very much man, simple and easy.