How stomach acid meds may cause heart attacks, dementia, and gut microbiome changes
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- เผยแพร่เมื่อ 10 ก.ย. 2024
- Proton Pump Inhibitors (PPIs) like omeprazole and lansoprazole are commonly used for stomach acid problems like heart burn, acid reflux and indigestion, but they have some very concerning adverse effects that patient's are not often warned about. These include increased risk of cardiovascular disease (e.g. heart attacks) via their action on nitric oxide, increased risk of dementia, vitamin and mineral absorption issues (B12, magnesium, calcium, iron, vitamin C), increased risk of bone fractures due to their effects on bone metabolism, and gut microbiome changes, and increased risk of Small intestinal bacterial overgrowth (SIBO) and intestinal infections including C.diff (Clostridium difficile). Rather than taking antacids, I go through 10 lifestyle interventions that can help cure your stomach acid and stomach lining problems.
1. Time restricted eating (/ intermittant fasting). Proper overnight fast.
2. Gap between last food of the day and bedtime.
3. Weight loss.
4. Eliminating overly processed foods (including energy drinks)
5. Eliminating caffeinated drinks.
6. Eliminating alcohol.
7. Stopping smoking.
8. Stopping hot / spicy food.
9. Considering all pharmaceutical medications / drugs.
10. Reducing stress.
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References / Further Reading:
PPIs and Heart Disease:
www.ncbi.nlm.n...
‘PPIs appear to be associated with elevated risk of MI in the general population’
www.ncbi.nlm.n...
www.ncbi.nlm.n...
PPIs and Bone Fracture:
www.ncbi.nlm.n...
‘long-term PPI use is associated with a modest but rather consistent increase in the risk of fragility fracture.’
PPIs and Dementia:
pubmed.ncbi.nl...
‘PPIs can affect brain cells through various mechanisms, for example, by increasing beta-amyloid levels, involved in the development of AD. Long-term exposure may additionally increase vascular dysfunction by impairing endothelial function, thereby accelerating the progression of cerebrovascular damage potentially leading to vascular dementia.’
PPIs and gut microbiome:
www.ncbi.nlm.n...
‘PPIs can affect the composition of gut microbiota and modulate the immune response….their long-term use can contribute to small intestinal bacterial overgrowth (SIBO) or C. difficile and other intestinal infections.’
PPIs and mineral absorption:
www.ncbi.nlm.n...
‘PPIs have been associated with an increased risk of vitamin and mineral deficiencies impacting vitamin B12, vitamin C, calcium, iron and magnesium metabolism.’
Dr Philip Bosanquet
The Low-Tech Lifestyle Medic
All content (other than referenced material) copyright to Dr Philip Bosanquet 2023 ©
Thank you
Fasting between 6pm and 630am has helped me reduce my lansoprazole dose by half, and hopefully I will eventually stop it. (After taking it for 8 years, and no doctor has ever encouraged me to try something different, I had to figure it out myself! )
That's great, nice one. You really do have to become your own detective to figure these things out. I hope some of the tips here can help you too.
Same for me it's just there on repeat all the time ..
Great video, thank you. I've spent the last year eating a much more nutrient based diet and Sun pm - Fri am I had a 6 hour eating window, with this I completely stopped taken Omeprazole many months ago and still allow myself a sensible treat on Fri and Sat.
Fantastic that you got off omeprazole with that shorter eating window. Nice one!
They cause kidney failure and Barratts ousophagus. My dad had to have his kidneys checked yearly. He got both of these side effects. He was given PPIs after they gave him a duodenal ulcer giving him aspirin and warfarin. 🙄. I keep away from Drs tbh.
Thanks so much for this information. Just subscribed!
Your very welcome for info, and thanks for subscribing :)
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Awesome, thank you!
I can’t tell my Dad to not take Prilosec every night. I said it’s only supposed to be a very temporary med, and has some very significant issues when taken long term.🤦🏻♀️
He said “I don’t want esophageal cancer”. (He knew someone with acid reflux, who then had esophageal CA.)
So “that’s that”.
Well PPIs can cause Barratts oesophagus so there's that. Caused me dad's. Which increases the risk of oesophagus cancer.. so there's that.
I know that fear I'm scared to stop them too for that reason..
I'm going to do the 12 hour fasting and see if it helps, I've already adjusted my food ..
@@thathurt , I know… my parents used to ask me questions and listen to me, about health and medical related issues. But starting a few years ago, they stopped coming to me about any of it. (because I was wary of the broad public health problem and solutions)
When I noticed my dad was taking Prilosec every night and asked about it, he gave me that quick, matter of fact answer.
Hopefully things will become more “normal” again and they won’t treat me like the cable news networks have been telling them to for the last several years.
I've made most of these changes (save for morning coffee (only 1 cup)) and 1 small beer per week. I have a hiatus hernia. What are my options, beside a PPI?
LocalYokel01,
I have seen some exercises. I wonder if they can be somewhat helpful for HH.
@@RosellaHomecare What exercises would those be?
Sorry to push back, Dr B, but I cannot agree that every human more than a few months old should elect time-restricted eating. Bad idea, methinks, for chronically underweight folks, or for people with a history of anorexia or bulimia or starvation. And what about pregnant people…? 😮 😮😮
Push back good :) When I think of measuring age in months, I'm thinking of up to say 18-24 months. Obviously don't need to push it in this age group, but once a child drops night feed then 12 hour fast overnight is normal and good (will happen naturally when fed a proper diet). In contrast I hear parents leaving a fruit juice bottle in kids beds overnight not infrequently - not good! Time restricted eating good for pregnancy, obviously again a situation not to be pushing any limits, but normal 12-14 hour overnight fast is appropriate. Still leaves 10-12 hours for 3 good meals. Of course in case of anorexia etc then time restricted eating would not really be relevant I agree, although at the same time the solution to these issues is not extended eating hours, but addressing the mental health aspect.