@@hussainbiology Shabir, Thank you for asking. Bert (my English Golden Retriever) is doing amazingly well. The right hip surgery was a success (double pelvic osteotomy). He has much better performance in the field. Jumping up on boulders--out of the creek bed. His left hip of course is still dysplastic but the right hip works much better. Overall he is improved from before surgery. BTW, children born with acetabular dysplasia (aka congenital hip dislocation) have a similar operation called an acetabular osteotomy (the orthopedic surgeon makes 3 bone cuts in the acetabulum, rotate it to better cover the femoral head, and then bolt it back together. Bert!! By the way, I Googled the SARS 2 spike protein and read some research articles. It's a busy polypeptide with multiple motifs! Some of the regions mutate (as discussed in your video) and others are somewhat conserved. The vaccines that work against the epitopes of the conserved regions will be more successful against the mutants. I'm not quite sure on the correct usage of region, motif, or domain when it comes to polypeptides? I read some of this but it was a little too detailed for me. www.mdpi.com/1999-4915/13/1/109/htm I hope you are well and I look forward to your next video!! 🌷💗🎵🌼🎥🎬
I was hoping you could comment on a BBC report that stated: "The South Africa and Brazil variants also have a key mutation, called E484K, that may help the virus evade antibodies, key parts of the immune system which help bodies fight off infection." If the virus is able to evade antibodies wouldn't that make vaccines ineffective?
Yes it makes vaccines ineffective but in the mean time Vaccines should be updated simultaneously to overcome these mutations that is why it takes decades to make one stable Vaccine for any virus or we could totally fail if we have mutations like of HIV virus .... We hope it Stops mutating and we find the one stable Vaccine for it.
Nice, easy to understand , precise and power packed presentation.
Excellent I was in search of such explanation nicely explained hats off
Shabir, Thank you for researching and presenting this information! 😊👏👏😊
thanks Dr Mike for appreciation.... and yes How is Bert now ???
@@hussainbiology Shabir, Thank you for asking. Bert (my English Golden Retriever) is doing amazingly well. The right hip surgery was a success (double pelvic osteotomy). He has much better performance in the field. Jumping up on boulders--out of the creek bed. His left hip of course is still dysplastic but the right hip works much better. Overall he is improved from before surgery. BTW, children born with acetabular dysplasia (aka congenital hip dislocation) have a similar operation called an acetabular osteotomy (the orthopedic surgeon makes 3 bone cuts in the acetabulum, rotate it to better cover the femoral head, and then bolt it back together. Bert!!
By the way, I Googled the SARS 2 spike protein and read some research articles. It's a busy polypeptide with multiple motifs! Some of the regions mutate (as discussed in your video) and others are somewhat conserved. The vaccines that work against the epitopes of the conserved regions will be more successful against the mutants. I'm not quite sure on the correct usage of region, motif, or domain when it comes to polypeptides?
I read some of this but it was a little too detailed for me.
www.mdpi.com/1999-4915/13/1/109/htm
I hope you are well and I look forward to your next video!! 🌷💗🎵🌼🎥🎬
thank you so much!
I was hoping you could comment on a BBC report that stated:
"The South Africa and Brazil variants also have a key mutation, called E484K, that may help the virus evade antibodies, key parts of the immune system which help bodies fight off infection."
If the virus is able to evade antibodies wouldn't that make vaccines ineffective?
Yes it makes vaccines ineffective but in the mean time Vaccines should be updated simultaneously to overcome these mutations that is why it takes decades to make one stable Vaccine for any virus or we could totally fail if we have mutations like of HIV virus ....
We hope it Stops mutating and we find the one stable Vaccine for it.
@@hussainbiology Thank you for the information. 😊
Sir plz make a vd on these topic
Aging and Senescence
Nicely presented
Thankyou so much 🙏🙏🙏
Most welcome
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That's why, we need fast vaccination program so that we can restrict this virus mutation. More mutations decrease vaccine effectiveness
surely
That won't happen because it only takes 10 hours to mutate and replicate in host. It's like chasing one's tail
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