DNA Replication: Copying the Molecule of Life
ฝัง
- เผยแพร่เมื่อ 7 ก.ย. 2016
- Your DNA needs to be in every cell in your body, so what happens when cells divide? How does each new cell retain all of the genetic information? The DNA is able to copy itself through a process called replication. Let's go through the finer points, shall we?
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Gotta love how with quarantined schooling teachers have given up on teaching and recognized that people like you have been the ones actually teaching us.
that why im currently watching this
@@Emily-gy8pe same!
🙌🏽
Professors and teachers are getting lazy and it is so much easier for them to just send us to a website and let someone else explain it! Thank you!
You literally just summarized about half of what I learned in an entire semester-long molecular biology class in a 6 minute video. Nice.
Dang what!?!?!?!
really this is day one for us..... it is fricking hard XD
I love that I can learn by watching videos. I am interested in many subjects and my idea of a good session is learning something new. I will definitely be checking out Professor Dave!
Even with a biology degree and in medical school, this is the most straight forward and easy to understand video on DNA replication. You sir are the GOAT.
You single handedly made me not only pass but EXCEL in my biology 101 class. Thank you professor dave
I just realized something very important in terms of how to interpret your animation.
The directionality of the synthesis of the new strand is correct. However, I initially thought that the numbers you put on the leading strand was identifying the ends of the new strand, not the original strand.
In other words, the new strand would read/synthesize as such: 3' under the 5' of the leading strand and 5' under the 3' of the leading strand with the arrow going in the same direction.
Bro, why does the microscopic world low key feels like a mini-society
Every time I struggle to understand a course material and find out you have a video for it, I cry tears of joy
Doesn't polymerase travel 5' to 3' not 3' to 5'?
I have a biochem exam tomorrow and I could not keep the enzymes and their functions straight. Now I think I’ve got the hang of it! Thanks, Professor Dave
Thank you Prof. Dave! I spent like two hours trying to understand my professors lecture, and you helped quite a lot! I am really grateful that I found this video online. Thank you for what you do! :)
A great, fast, easy and organized video! Thanks!
I love the way you explain each step of DNA replication and other biological processes in your videos, I'm just glad to find your channel :')
I enjoy that I can learn the basics from your mini-lectures. Great job, Professor Dave. You put me in mind of my late father, a physician, teaching me about reproduction, mitosis, meiosis, etc. He started with onions and went on from there, ending with human reproduction when he felt it was age-appropriate (about 13-14 in my case). This puts me in mind of his teaching methods.
I just subscribed a couple of hours ago and will be adding your videos to my Geology/Volcanology and Evolution and Extinctions playlists. So glad I found your channel!
sir you are a really talented teacher and a speaker ...... a process which would take me hrs to understand was made easy by you and i got it in juat 6 mins ! thanks man
That Addicted Guy you forgot the 15 seconds
This helped me so so much! Your video really cleared this up! Thank you!
Video was crystal clear . I understood the whole topic In ONLY 6 minutes where I didn’t get one thing through my head in a 80 minute class . Thank you so much Professor Dave !!
I like the fact that what I learned here was better than what I learned in school, more detailed and compact
Keep it up 😊
Thanks for this explanation. Some things are simplified. But this is a very good overview. It was really helpful.
You are awesome.. I was jumping from video to another and I can’t understand that. But with you just in 6 min I take it very well !!
This is one of the best videos I have seen on DNA Replication!! thanks a whole whole lot!!
If only I had you as my lecturer ! Absolute legend mate!
Loving the vids, I'm revising what I learned in the balkan equivalent of advanced biology & chemistry highschool.
Just one thing: the audio volume is a bit low everywhere except the intro. These are old af but if you plan to make more videos maybe amplify the volume a bit in post.
This is such a great video! short and sweet :)
Your videos are so helpful!
Thank you for this.. I had no idea what was going on until I saw your videos! Thank you so so much!
Super helpful! Would have taken hours for me to understand just by reading this.
Thank you Sir!
Best explanation I've ever heard and seen my whole life. Ily.
Great explanation, thanks!
Its perfect!!!!😍
Each time i want to search for something scientific i find a video for you, your explanation is perfecttttt, keep on Dr.♥️
Thank you so much Prof Dave
I wish you could explain the rolling cycle mechanism too
Explained in very easy and simple manner... Thank u sir
Easy & concept clear explanation.... thank you sir.
Watched so many videos on this and this one finally made sense. Thank you!
thank you so much, i am so grateful for this video. Explanations are perfect.
I'm in 12 standard from INDIA 🇮🇳 & I found this video which really boosted my knowledge ☺
Your explanation is very clear and the footnotes are very helpful, i now can understand the replication process thankyou prof
Spending hours in boring college lectures with professors that lack the ability to teach and not learning ANYTHİNG vs watching a 6 minute video from a great teacher and understanding everything. I think I have spoken enough
Do you have a video about endogenous retroviruses (ERVs)? Would like to get a better grasp about the subject.
Thanks for these videos btw. Really helpful.
Thank you sir
I spend 2 days on this topic but this 6 minutes video clear my concepts too much
Thank proff Devi .....am really enjoy your session
5' and 3' DNA template strand should be more specific indicated in the slide. Its a little bit confusing.
yeah a lot of people have mentioned this, i wish i had made it a bit more clear. nothing i can do now!
Yes, he needs to label the new and old strand as it is very confusing (he's labeling the old strand)......this is where students get mixed up often.
@@ProfessorDaveExplains
You should make another video...
Please sir this is a humble request...
All the videos I have viewed on DNA replication struggle to explain the 5'-3' process. Unfortunately, this wasn't any better, but the rest of the video was helpful.
@@ProfessorDaveExplains annotations?
Excellent video, Thanks!
I have a final task in Genetics, thanks for this vid. It means a lot to me!
Awesome description!!!!
Wow! I love the lecture. Thank you Prof
Thank you so much! You helped clarify a lot of areas that my textbook failed to properly explain.
You remind me of an off-brand Dave Grohl and it makes studying way easier, thank you
This man has Taught me for 3 separate courses, its amazing
it was beautiful sir. it helped me memorize it smoothly.
Its so frustrating, I understand the protein syntecis, the DNAs structure, mitoses and meiose, transcription, translation etc. when I get it explained to me, but there is no way I can repeat it😂😭
thank you so much for your explaining
From Professor to Professor 👉🏼 you are great !!!
Thank you for saving my exam! Very clear and well structured explanation.
You’re a life saver Professor Dave..
DNA chain can only be synthesized in 5'-to-3' direction, not 3 to 5. As the subunits is being added at the 3' end, that means it runs in 5'-to-3' direction....
Bawan Colnadar I noticed that error in the vid as well
He's going to get people confused. Need an upgrade.
Actually he's correct, the DNA polymerase III moves in a direction of 3'- 5' of the preexisting strand. However, the new strand that's being synthesized is 5'-'3. The video is crystal clear .
The video is correct, but NOT clear. This "Dave" person knows the stuff but doesn't know how to explain it to a naive mind. Someone listening to this for the first time can get confused for all his life !
REPLICATION HAPPENS FROM 5 to 3 END !
Sounds like you're not interested in using your logic only in memorizing facts.
This is the only video I've seen that accurately explains the difference in role of Topoisomerase and Helicase...Thank you
I love u Prof. Dave , u made it simpler
Makes so much more sense hearing it from you vs. in class
great refresher vid, great name
you're the real MVP! and I love your intro lol it's hella catchy and cute
Thank you so much sir.... It really helped✌️👌
Thank you! Very helpful! Which okazaki fragment will be placed first in the lagging strand?
Well explained. Thanks!
Nice explanation..
You're a good man Dave!!! Thank you thank you !
great as always .
Thank you, Dave!
Not sure if nitpicky or not but it could help to clarify that DNA polymerase III/I are those used in prokaryotes. I remember in high school still using the terms generically but I believe DNA pol-alpha/delta are the current standards for eukaryotes?
Great work sir
Thanks professor. Such helpful video
I love your video overall. However, I think in this video (and video series) you should explain what does anti-parallel and 3' 5' mean here.
That’s covered in the tutorial on nucleic acids.
@@ProfessorDaveExplains Thanks for the reply. I think it is still hard to connect this 3' and 5' to the phosphate and OH on the saccharide ring in nucleic acid, and then connect to how they orient in the DNA backbone. The gap is a bit large for the student to fill in themselves.
Chatgpt and another video that visualize the 3' and 5' along the backbone, helped me to understand it.
Anyway, you videos are still fantastic. They are the best I can find online. Almost all the information are sufficient (ie, useful) and necessary (ie, minimal) to build upon each other. These video are extremely time-efficient in learning roughly what the field is about. Thanks you very much for these amazing videos!
hi professor. i thought polymerase creates the leading strand in a 5'-3' direction towards the fork?
Sir, can you state the difference between DNA polymerase alpha beta, gamma, delta,epsilon and DNA polymerase 1,2,3??
Easy understanding explanation
Very detailed. Thank you very much! ♥️
Amazing explanation
nice explanation!!
thank you for your great explanation
This video is perfect thanks a lot sir.
I can leisurely watch Professor Dave in my free time and enjoy every second learning as many videos as I can.
Well explained!!
U r the best.... Respect SIR. ❤❤❤
You Are Great Sir...
Really helpful!
hi prof, had a few doubts:
1. after binding the primer to the DNA strand, the primase leaves the spot, and DNA polymerase iii takes the same spot to start adding the free DNA nucleotides?
2. on which strand do the following take place first or do the following processes take place simultaneously (as there is one molecule of enzyme allocated for each strand?) on both the strands?
a) exonuclease removing the RNA nucleotides/primers
b) DNA polymerase I adding DNA nucleotides in place of the primers
c) Primase adding primers
d) polymerase III adding free DNA nucleotides
Great video... But did you forget SSBPs??
very much well explained
Thank you was very helpful with my project
Thank you.
Thank You So much Sir
Thanks for the help. Now I get DNA replication better than ever!
I got more than I asked for! A lot of these stuff aren’t part of my textbook but I don’t care. I’ve always wanted to learn this anyway.
Whenever I am in need of help in biology, I go to this dude! Nice job! 👍🏻
Thanks for hearting!
Can you explain the difference between DNA pol 1 and pol 3 a little more? I'm not getting it
holy shit i've been looking for videos like this all year
search no longer!
great vid!
easy to understand .........fablous
you are truly God sent Prof. Dave
Dave, polymerase III reads from 3' to 5' but polymerases new strand from 5' to 3'? But you said polymerase copies 3' to 5'. Did you mean polymerase reads 3' to 5'?
I said moves along the template strand, so yes "reads" would be a good way to interpret that.
Great work thanks alot