What could also be mentioned in this video are the post ebola symptoms such as opthalmitis, blurred vision, blindness, joint and musculoskeletal problems, neurological problems, loss of hair, hairing defect and memory problems. These are extremely debilitating symptoms and are important to keep in mind after recovery from the initial ilness.
Thank you, this was ridiculously helpful for me. I am making a stop motion animation short of ebola viral replication. This is probably the most specific, clear and simplistic (easy to grasp) video I've seen. Thank you for making my research project about ten times less stressful!
One of the strangest things I have noticed about ebola is that when people catch it they feel a strong urge to go to the airport and get on board an airplane the is flying across the country in close proximity with a hundred other people .
OMG, THANK YOU. Me and my friend do a project who talks about ebola virus. And all the informations we have is big complicate information from doctor research. But your video, it explains with simple word and picture all the thing we need to know to finish the project. thank you
+pinkabrablen Sorry if i make spelling mistake, i sspeak french. But no, Ebola was a really difficult project, because even the scientist did not really know how the virus work.I would like to help you, but i can't answer your question.
HI armando , i always watch your videos but now you had just fast forwarded it , and it was a bit too fast to explain fully, for doctors its ok and good, but for public it was too fast.
Thank you for this informative video, I am thinking if the role of immune system cells is to defend against the virus Does this virus reduce this type of cell because it make the role of the immune cell the opposite 🤔🤔
So how concentrated must the virus be in the infected person's system for it to be detected in an Ebola Test? Also, is it possible for an infected person to show negative on the Ebola Test simply because the virus isn't concentrated enough -yet? Is it possible for symptoms to still develop later on in the 21 day incubation period, thus receiving a positive diagnosis for Ebola, despite the initial results? Also "direct contact" is vague. What exactly qualifies as "direct"? Specifics, please.
All viruses need to be at a certain “concentration” until they are detectable. It varies between viruses and I’m not sure what it is for Ebola. The incubation period is typically 2-21, it’s not limited to that as there are exceptions and everyone reacts differently. False negatives/positives happen all the time, double or triple checking with multiple tests is always recommended. Direct contact is a medical term meaning infected bodily fluids must make direct contact with your bodily fluids. Basically if you have a cut and touch infected fluids or if infected fluids enter your mouth/nose/eyes.
Ebola L-polymerase is a protein necessary for the replication. It is an RNA-dependent RNA polymerase (RdRp) that speeds up the transcription process of viral mRNAs!
I come from Indonesia, I came here to look for information related to the Ebola virus to complete my assignment at school, there is very little material related to the Ebola virus in Indonesia so I had a really hard time finding sources of information about this virus and in the end I only found this material It's just that this material doesn't use Indonesian so I have difficulty understanding it😭
There were many epidemics and even pandemics caused by it. it is just that the documents of it happening haven't been found yet or don't even exist nowadays. in fact the plague of Athens was likely Ebola Zaire. we just don't know.
One, documentation. Two, it is believed to have started from bushmeat consumption. It could’ve arisen because a community needed a new food source and they happened to eat some infected bat.
I may be wrong, but I am pretty sure bats are able to survive Ebola infection. They are the host species for this disease meaning they carry it and survive with it. But it can be passed to other species and kill those.
You essentially described a vaccine! There are so many different steps in the replication process that can be attacked. That is the main idea behind vaccines but it isn’t always that simple! The main goal of vaccines is to illicit an immune response and teach your body how to attack the virus before it attacks you. Check out the different types of vaccines to learn more!
The immune system is strong enough to hold of the disease, so the Ebola virus incubates in hard to reach areas, such as the genitals of the animal or the eyes.
Excellent, thank you so much. My 15 year-old son who doesn't want to know anything about EVD (we're in the U.S. unfortunately) might watch this video of yours because it presents a scientific, educational perspective about EVD. I will try to get him to watch it. He probably figures I'll take care of prevention (megadoses of Liposomal Vitamin C and Colloidal Silver (and possibly Oil of Oregano (Oreganol P73) all of which are suggested by some naturopathic doctors to help vanquish EVD. Both Colloidal Silver and Oreganol P 73 are suggested to combat other various viruses, bacteria and fungi, both topically and internally). In lieu of having an effective licensed vaccine (and actually being reluctant to take an Ebola vaccine given the possibility that not all of the Ebola virus in the vaccine is killed, and in general what other concerning ingredients might be in the vaccine, such as formaldehyde, aluminum, thimerosal, and foreign animal tissues - I would trust the above-mentioned treatments over an Ebola vaccine, also because its approval is currently on a fast track and probably hasn't yet been studied for side effects over the longer term). I also have about 50 N95 and some P100 respirator masks, some airtight goggles, some sterile gloves, and some Hibiclens, a medical grade hand sanitizer that acts like an invisible glove for hours after it's applied. I only have two of those Kimberley Clark white suit sets, including booties, though. I need to order some more. I'm not of course a doctor but I've spent the past 20+ years investigating these issues, ever since my 25 year-old autistic son was a toddler. Thanks again for this very helpful presentation! I'll sub to your channel.
We now have a vaccine for Ebola and it’s only recommended for those with increased chance of contact. Those of us in the US currently do not have anything to worry about. The amount of testing vaccines go through before reaching human testing is a lot. Also, viruses belonging to the same family provide beneficial information that can help develop these vaccines. For example, the Covid vaccine was not thrown out there on the fast track. Yes, some of the process was expedited but coronaviruses have been studied for more than 20 years. There are also different types of vaccines, live-attenuated, VLP, etc. not all contain live virus. And those that do, the virus has been debilitated and does not have certain factors it needs in order for replication to occur. With what we learned from the Salk vaccine, there are rules and standards in place to prevent an infectious vaccine. I appreciate that different diseases can be treated/improved w/ natural medicines but we cannot ignore the science and research that so many people dedicated their careers for.
let me help u suppose u need to bake a cake. u have a recipe how to cook the ake but u do not have the ingredients to make the cake like flour, egg ,butter and a oven to bake the cake. what you do now? u can go to u r friends kitchen who has all the ingredients. viola now you have all the ingredients and the recipe u can bake the cake think of virus same it has a DNA or RNA which is like a recipe to make more virus but does not have ribosome and other componets which are required to make virus so what it can do? it can enter a host cell (in case of ebola its fruit bat) take the ingredients from the bat's cell and make more virus and continue its generation i hope i helped you :)
Viruses cannot replicate or reproduce independently, unlike cells in our body can replicate into 2 cells from one. What viruses do is use the host (animals/bats in this case) cells for their metabolic pathways. So basically, cells in our body replicate asexually (by themselves/independently) and the virus can take up those cells and it will replicate the virus with it. Some take 25 min (for plants) and up to 24 hours for animals! Look up: Lytic Cycle and Lysogenic cycle! Easier to understand:)
This is a new strain. When did it change? On the monkey/bat (meat) or in the human? Is it an adaptation after the vaccine? Are there different types of Ebola?
Some viruses mutate quicker than others. It depends on their genetic makeup and how the host reacts to the virus. Some mutations are immune to the vaccine. There are many Ebola virus strains. Ebola virus itself is part of the filoviridae family.
Jim Battersbee Awesome, I'm in my final year of my Microbiology degree. Viruses aren't really my area of expertise at all but some of them are interesting.
Airborne mutations are not a thing. Mutations have to occur within the human body because the thing mutating is the virus. In order for a virus to mutate it needs a host.
The likelihood of that eliminating the virus is slim. We need bats. Any time a species is eliminated, the ecosystem in which they live in are disrupted. Ebola is also present in other species as well.
It is also by respiratory and every other means: saliva, sweat, semen, urine, hemorrhagic diarrhea, and the hematuresis. This guy also needs to get his facts straight, too, unless Richard Preston had his facts wrong.
Good video, just want to say that Ebola hemorrhagic fever is now an out of date term and that infection is not just from fruit bats. It is now known that it can be spread from person to person with bodily secretions, blood transfusions, sharing needles etc. Although, cannot be transmitted through mosquitoes. :)
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Thank you dear Armando, your knowledge and artistry is truly exquisite. To postulate otherwise would be decidedly futile.
What could also be mentioned in this video are the post ebola symptoms such as opthalmitis, blurred vision, blindness, joint and musculoskeletal problems, neurological problems, loss of hair, hairing defect and memory problems. These are extremely debilitating symptoms and are important to keep in mind after recovery from the initial ilness.
loved your videos...thank you so much as it helped me to study during my exams
Thank you, this was ridiculously helpful for me. I am making a stop motion animation short of ebola viral replication. This is probably the most specific, clear and simplistic (easy to grasp) video I've seen.
Thank you for making my research project about ten times less stressful!
Wonderful effort as always. Very informative and easy to watch
Thank you 😀😀
You are a good artist too. :)
The affected immune cells and human cells you mention are mainly endothelial cells, phagocytes and hepatocytes.
One of the strangest things I have noticed about ebola is that when people catch it they feel a strong urge to go to the airport and get on board an airplane the is flying across the country in close proximity with a hundred other people .
I would still like to find out more about inflammatory bowel disease and Crohn's disease. Also IN A.
Thank you. It is very helpful.
thank you so much it really helps my assignment
Thank you so much, creativity video 💜
Nice artwork dude
Hi Armando! What a great video! Would you mind if I remake it in spanish?
Thank you so much!
I supose you don´t have the exact article do you? It would help a looot !!!
Writing my senior thesis on ebola virus. This was very helpful!
What was your grade? Did you pass?
i know im 7 years late to the party but i just want to say that your a life saver my dude
Thank you so much! This helped me a lot :)
thanks for making this video short YAY LESS WORKKKK
Hi, do you know what kind of ELISA could we use to make the diagnosis?
OMG, THANK YOU. Me and my friend do a project who talks about ebola virus. And all the informations we have is big complicate information from doctor research. But your video, it explains with simple word and picture all the thing we need to know to finish the project. thank you
Hi, sorry for the question but when you did your project... did you find the kind of ELISA that is used to make the diagnosis?
+pinkabrablen Sorry if i make spelling mistake, i sspeak french. But no, Ebola was a really difficult project, because even the scientist did not really know how the virus work.I would like to help you, but i can't answer your question.
+pinkabrablen ow, sorry, Proud Nova and Antony Courchaine are the same person, just two different account
+Proud James Oh I understand, don't worry. A lot of thanks :)
Yes I agree
HI armando , i always watch your videos but now you had just fast forwarded it , and it was a bit too fast to explain fully, for doctors its ok and good, but for public it was too fast.
Thanks for the clear information. well apreciated.
That pause to google how to spell diarrhea. lol
Hey, I know I am very late to comment, but I have research that should be done soon. Does the Ebola virus do a lytic or lysogenic cycle?
it does the lytic cycle, the lysogenic cycle isn't possible for RNA virus' unless they're retroviruses.
I've had ebola 2x ...coca cola cured me.
can you PLEASE do one on Dengue Fever!!!!
Excellent
CN you please make a video of legionella?
thank you!!! so good!!
Thank you for this informative video, I am thinking if the role of immune system cells is to defend against the virus Does this virus reduce this type of cell because it make the role of the immune cell the opposite 🤔🤔
Thank you
Thanks very clear
Thank u am in Uganda and this good for us
So how concentrated must the virus be in the infected person's system for it to be detected in an Ebola Test? Also, is it possible for an infected person to show negative on the Ebola Test simply because the virus isn't concentrated enough -yet? Is it possible for symptoms to still develop later on in the 21 day incubation period, thus receiving a positive diagnosis for Ebola, despite the initial results?
Also "direct contact" is vague. What exactly qualifies as "direct"? Specifics, please.
All viruses need to be at a certain “concentration” until they are detectable. It varies between viruses and I’m not sure what it is for Ebola. The incubation period is typically 2-21, it’s not limited to that as there are exceptions and everyone reacts differently. False negatives/positives happen all the time, double or triple checking with multiple tests is always recommended. Direct contact is a medical term meaning infected bodily fluids must make direct contact with your bodily fluids. Basically if you have a cut and touch infected fluids or if infected fluids enter your mouth/nose/eyes.
what does the polymerase do in this? since you mentioned it. I didnt understand what its role
Ebola L-polymerase is a protein necessary for the replication. It is an RNA-dependent RNA polymerase (RdRp) that speeds up the transcription process of viral mRNAs!
pleas more videos about viruses
I come from Indonesia, I came here to look for information related to the Ebola virus to complete my assignment at school, there is very little material related to the Ebola virus in Indonesia so I had a really hard time finding sources of information about this virus and in the end I only found this material It's just that this material doesn't use Indonesian so I have difficulty understanding it😭
Why people lived in same conditions for centuries and there was no Ebola Virus?
Ebola virus has been around since 1976, it's just been controlled so has only affected a couple of 100 at the most compared to the current outbreak.
We didn't know that the virus existed
There were many epidemics and even pandemics caused by it. it is just that the documents of it happening haven't been found yet or don't even exist nowadays. in fact the plague of Athens was likely Ebola Zaire. we just don't know.
One, documentation. Two, it is believed to have started from bushmeat consumption. It could’ve arisen because a community needed a new food source and they happened to eat some infected bat.
man i was suppose to be watching your breathing lecture not the ebola virus ughhh …your lectures are too interesting.
Kaise ho
Great!
can you explain how replication occurs in more detail?
Alexis Meyer Or you could just search for yourself rather than wait for him to do that.
+NiKtHeB0Ss I've done an ebola research project and a lot of explanations out there are difficult to grasp. Visuals are helpful.
Good video
Thanks! But I was wondering would the bats keep alive after catching ebola virus without display any symptoms?
I may be wrong, but I am pretty sure bats are able to survive Ebola infection. They are the host species for this disease meaning they carry it and survive with it. But it can be passed to other species and kill those.
Help me a lot!😊
Now in Mexico America Bahamas. Europe Sweden Spain , they are keeping it quiet 🤫.
I am watching after 5 years 😯when the Corovirus😷 Wichita I don’t get it lol 😝
I'm watching after 8 years😮 damn corona was long back ago.
cool...
Interesting
What if you could make a genetically modded version which has limited replication efficiency so that eventually immune cells can recognize the virus
You essentially described a vaccine! There are so many different steps in the replication process that can be attacked. That is the main idea behind vaccines but it isn’t always that simple! The main goal of vaccines is to illicit an immune response and teach your body how to attack the virus before it attacks you. Check out the different types of vaccines to learn more!
seems a bit generic, other than the death rate
God save them
God forgive me
How come the virus does not kill the bat but kills the human?
because humans are different to bats
+hyung jin Ahn Bats are what are called carriors of the disease.
The immune system is strong enough to hold of the disease, so the Ebola virus incubates in hard to reach areas, such as the genitals of the animal or the eyes.
Excellent, thank you so much. My 15 year-old son who doesn't want to know anything about EVD (we're in the U.S. unfortunately) might watch this video of yours because it presents a scientific, educational perspective about EVD. I will try to get him to watch it. He probably figures I'll take care of prevention (megadoses of Liposomal Vitamin C and Colloidal Silver (and possibly Oil of Oregano (Oreganol P73) all of which are suggested by some naturopathic doctors to help vanquish EVD. Both Colloidal Silver and Oreganol P 73 are suggested to combat other various viruses, bacteria and fungi, both topically and internally). In lieu of having an effective licensed vaccine (and actually being reluctant to take an Ebola vaccine given the possibility that not all of the Ebola virus in the vaccine is killed, and in general what other concerning ingredients might be in the vaccine, such as formaldehyde, aluminum, thimerosal, and foreign animal tissues - I would trust the above-mentioned treatments over an Ebola vaccine, also because its approval is currently on a fast track and probably hasn't yet been studied for side effects over the longer term). I also have about 50 N95 and some P100 respirator masks, some airtight goggles, some sterile gloves, and some Hibiclens, a medical grade hand sanitizer that acts like an invisible glove for hours after it's applied. I only have two of those Kimberley Clark white suit sets, including booties, though. I need to order some more.
I'm not of course a doctor but I've spent the past 20+ years investigating these issues, ever since my 25 year-old autistic son was a toddler. Thanks again for this very helpful presentation! I'll sub to your channel.
Wow why does your son not want to learn about this? Its life or death, this world will never eliminate death and even kids have to struggle to survive
We now have a vaccine for Ebola and it’s only recommended for those with increased chance of contact. Those of us in the US currently do not have anything to worry about. The amount of testing vaccines go through before reaching human testing is a lot. Also, viruses belonging to the same family provide beneficial information that can help develop these vaccines. For example, the Covid vaccine was not thrown out there on the fast track. Yes, some of the process was expedited but coronaviruses have been studied for more than 20 years. There are also different types of vaccines, live-attenuated, VLP, etc. not all contain live virus. And those that do, the virus has been debilitated and does not have certain factors it needs in order for replication to occur. With what we learned from the Salk vaccine, there are rules and standards in place to prevent an infectious vaccine. I appreciate that different diseases can be treated/improved w/ natural medicines but we cannot ignore the science and research that so many people dedicated their careers for.
Why does it have to enter a cell (of the fruit bat) to replicate?
let me help u
suppose u need to bake a cake. u have a recipe how to cook the ake but u do not have the ingredients to make the cake like flour, egg ,butter and a oven to bake the cake.
what you do now?
u can go to u r friends kitchen who has all the ingredients.
viola now you have all the ingredients and the recipe
u can bake the cake
think of virus same
it has a DNA or RNA
which is like a recipe to make more virus but does not have ribosome and other componets which are required to make virus
so what it can do?
it can enter a host cell (in case of ebola its fruit bat) take the ingredients from the bat's cell and make more virus
and continue its generation
i hope i helped you :)
kamal poddar thats a really great analogy! think I'm gonna steal it if thats ok :)
You are most welcome
Happy to help
Viruses cannot replicate or reproduce independently, unlike cells in our body can replicate into 2 cells from one. What viruses do is use the host (animals/bats in this case) cells for their metabolic pathways. So basically, cells in our body replicate asexually (by themselves/independently) and the virus can take up those cells and it will replicate the virus with it. Some take 25 min (for plants) and up to 24 hours for animals!
Look up: Lytic Cycle and Lysogenic cycle! Easier to understand:)
if it is an RNA virus why does it need to undergo transcription before being translated?
Because it is a -RNK virus, and cannot be translated; therefore,it has to be transcripted to +RNK, that can go to further translation
Kristina Kostic thanks for the info
This is a new strain. When did it change? On the monkey/bat (meat) or in the human? Is it an adaptation after the vaccine? Are there different types of Ebola?
Some viruses mutate quicker than others. It depends on their genetic makeup and how the host reacts to the virus. Some mutations are immune to the vaccine. There are many Ebola virus strains. Ebola virus itself is part of the filoviridae family.
why transcription? It is RNA. It can be directly translated
It’s just part of how this class of virus replicates. It seems inefficient but it is just how it evolved.
(Dead meme alert)
If you don't have ebola, you don't know de wae.
Wow, this is great drawing of how ebola infect human cells.
So what about an airborne mutation?
Jim Battersbee
I hope so, I have a virology exam today haha
Jim Battersbee
Awesome, I'm in my final year of my Microbiology degree. Viruses aren't really my area of expertise at all but some of them are interesting.
Airborne mutations are not a thing. Mutations have to occur within the human body because the thing mutating is the virus. In order for a virus to mutate it needs a host.
Shouldn’t you eliminate the bat population? Or enough to contain the virus? This is more of a preventative measure.
The likelihood of that eliminating the virus is slim. We need bats. Any time a species is eliminated, the ecosystem in which they live in are disrupted. Ebola is also present in other species as well.
It is also by respiratory and every other means: saliva, sweat, semen, urine, hemorrhagic diarrhea, and the hematuresis. This guy also needs to get his facts straight, too, unless Richard Preston had his facts wrong.
Did you watch the video? He said bodily fluids which is literally all the stuff you listed. His facts are straight.
2023 here now there's a vaccine right!
thank you, i love you so much i hope will be Muslim one day :)
wat
ew gross.
*****
Yes, the more the merrier. Come to the dark side, we have cookies.
It was a joke, not a debate about theology.
Volatix haaaaaaaaaaa! Now i understand. That cool
#obola
Good video, just want to say that Ebola hemorrhagic fever is now an out of date term and that infection is not just from fruit bats.
It is now known that it can be spread from person to person with bodily secretions, blood transfusions, sharing needles etc. Although, cannot be transmitted through mosquitoes. :)
He did mention that hemorrhagic fever is outdated and how it’s spread……….
you forgot to illustrate the contaminated vaccine that gives the human the EVD.lol.
BUILD IT. TRUMP.
CN you please make a video of legionella?
thank you, i love you so much i hope will be Muslim one day :)