ฝัง
- เผยแพร่เมื่อ 27 ก.ย. 2024
- This video is about how ketone body synthesis. All the enzymes and reactions involved in ketone body synthesis is explained in the video. Ketone body synthesis involves beta oxidation of fatty acids to provide acetyl CoA.
ketone body oxidation: goo.gl/kuJdJB
Energy from ketone body oxidation: goo.gl/fJGbeQ
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Thank u sir. Superrrrrrr explanation
Nice video! Now I understand why this is happening: because of nad+ for beta oxidation and TCA
That was mind blowing lecture sir....
Thank you
Extremely helpful and clear lesson!
I'm glad this video helped you.
Why not all Acetyl-CoA molecules from betaoxydation do net simply eneter Crebs cycle but are excreted to plasm to undergo ketogenesis and yet agin be excreted to blood ? thank you !
Understood!! God bless youuu!!❤️❤️🙏🏽
Hi! I have a question please.
Why we don't transport the Acetyle.Co.A molecule itself directly to the peripheral tissus that need energy, like the brain ?
Ohh thank you so much sir for making a video on this topic ... It really made the topic simpler !!!
You are most welcome
In HMG CoA isn't the 4th carbon the CH2 leading to the C=O (5th carbon) and SCoA? If those groups were included in the backbone chain it would explain the name of 3-hydroxy-3-methylglutaryl CoA.
+PhilosopherKingGaming _ :if you carefully look at the HMG CoA structure it is in fact has 5 carbon where 3rd carbon having OH and CH3 attached, but thanks for your question because I have noticed now that I did not release SCOA as CoASH from the molecule, it is still attached at 5th carbon where in fact the 5th carbon should be COO- it is a mistake from my side but other than that the 3rd carbon that is beta Caron has methyl and hydroxyl group.
Sorry, it just looked like when you went to number the carbons you labelled the 3rd carbon's methyl group as the fourth carbon in the chain, rather than a side group on the larger 5 carbon chain.
PhilosopherKingGaming _ : now I rewatched that exact part of the video and yes you are right, I carried away myself and numbered methyl group on the 4rd carbon as 4th carbon which is not true and also if you watch it carefully, while saying methyl group and hydroxyl group I was showing 4th and 5th carbon as methyl group which is a mistake from my side. thank you for noticing it. I truly appreciate it. I will add annotation at that point to correct the mistake. thanks again.
Happy to help, it's a really great video for review. Thank you for all the extra work and help. Hope you have a great time on the hike tomorrow and I'll see you in class on Monday.
good explanation
what is the rate limiting tep of ketogenesis?
Good one as usual Dr. Thanks
I'm gland this video has helped you.
Structure of HMG coA is incorrect.
Excellent video Sir. Tanx a lottttt
Excellent, thank you 👏
Thanks sir
great
Nice
brilliant :) had little difficulty catching some words but explained very well.
Thank you and wish you the best.
Ketone body synthesis happens in the hepatocyte mitochondria?
Yes thats true.
good lesson doctor Mungli
+Cristi Vlad : Thank you, I'm glad you liked the video.
thank you... nice and simplified ☺
You are most welcome.
Very nice
No one can explain the biochemistry concepts with such a precision like you do, sir. Thanks a lot.
V good Dr mungli but video is shaky
Thank you Dr Nasser. Yes this video is bit shaky the part of the reason for this is that I don't have any professional video recorder!
Thank you!