The pedigree examples at the end (example #1 and #2) were not proofread by a geneticist. I made them quickly just to illustrate visually what rule #1 and rule #2 may look like on a real pedigree. Obviously the other sex offspring not included in the relevant rule might be affected, but for simplicity sake i made them non-affected in the examples. This is not intended to be used to learn the nuances of genetics, this is to get points right on test day. TL:DR - just memorize rule #1 and rule #2 if you want to get all X-linked pedigrees correct.
you made a mistake making the pedigree in the middle at minute 4:03 the sons should be dominant X and recessive X not both dominant. But other wise this is great. Thanks
Hi, is this only applies from 1st generation to second one usually? or it is also applicable from 2nd generation to third one and then from third to fourth?
As a general pedigree structure/composition rule, aren't males always on the left and females are on the right in a couple that mates (ie:// example 1)
I have a pedigree where there is an affected father x wt female producing an affected daughter and unaffected son. But my professor stated all cases, autosomal dominant+recessive and x-linked dominant and recessive work here....but how cold I check for rule 2 here?
She does, mother shows equal inheritance while the father by transferring Y chromosome to son and X one to her daughter shows unequal inheritance. That was just an example for you to determine the possible genotype of parents in a pedigree.
So if the allele is recessive and affected sons don't come from affected mothers, can we say based on that info that the disease is not X linked? Someone please help
The pedigree examples at the end (example #1 and #2) were not proofread by a geneticist. I made them quickly just to illustrate visually what rule #1 and rule #2 may look like on a real pedigree. Obviously the other sex offspring not included in the relevant rule might be affected, but for simplicity sake i made them non-affected in the examples. This is not intended to be used to learn the nuances of genetics, this is to get points right on test day.
TL:DR - just memorize rule #1 and rule #2 if you want to get all X-linked pedigrees correct.
Mnemonic for X-linked Dominant:
X-linked *D*ominant = affected *D*aughters from affected *D*ads
pls make pedigree videos for ad n ar pls
thank u very much that was helpful....i have a Q .... can X-linked inhe come from a carrier? u didn't give us this example
Thanks Dirty!
Also shouldn't X-linked recessive be affected sons from unaffected mothers?
Thank you !!! This made it easier to remember @@abuilsult
I usually think Dad-Daughter->Dominant (DDD). Thank you for the video.
Thank you. It was helpful 👍🙂
thanks
It helps
Good one! 👌
Excellent
Damn you made something thats usually really complex to understand, easy thanks man !
Excellent and I think the most easiest way to overcome in understanding x linked diseases
I've been confused about x-linked pedigrees for a while, thank you for making this so clear.
since most of the people nowadays perform ASMR video, It is helpful to use it in MB exam:
ASMR;
Affected
Son
Mother
Recessive
Please make one on AR and AD too please!!
plssssss
Yeah please please please🙏🙏🙏🙏
Patiently waiting 😭
Still waiting 😢
Awesome as usual... Happy 2020, Dirty! And good luck for all the ones that are taking the test this year.
Please do explain the CARRIER GENE phenomenon too for XD and XR scenarios
you made a mistake making the pedigree in the middle at minute 4:03 the sons should be dominant X and recessive X not both dominant. But other wise this is great. Thanks
please also explain the chance of carrier carrying the gene , most of the quests are also related to this c
Thank you so much ! Exam in two hours I needed this
I did not get it in class and i expected it to be like super hard but it’s literally so easy! Thank u
right?!
lie
Thanks for this quick revision shot on Mendelian disorder traits in the Pedigree chart.
Thanks from India 🇮🇳. Post more of this ❤
This was so helpful. Thanks a lot Dirty !!
This was the simplest version ever❤thanks DDF😅😅
How we know whether its x linked or autosomal?
Can u make video on confidence interval and hypothesis testing for biostat
I subscribed because u made it so easy for me now😭😭
thanks a lot. I was really struggling, I really appreciate your tips.
The chart displayed at the very beginning....it is Autosomal recessive, right ???
how? shouldn't it be autosomal dominant
@@moob2020 yep dominant bec all the generation got the ds.
Amazing, thank you!
This was a great explanation, thank you!
Thank you so so much for making this video!!
Excellent Video, thank you.
have a gene exam tmr, this helped me a lot. thanks for the vid!
help me please
God bless you
This was so helpful, thank you so much!
you're amazing.Thank you
YOU ATE!!!
In the second punnet square both of the sons have The Gene A (dominant allel) but why it’s not effecting them??
Hi, is this only applies from 1st generation to second one usually? or it is also applicable from 2nd generation to third one and then from third to fourth?
I have a biology quiz tomorrow on this tyyyyy for making it really easy 💗
this helps me understand the X linked pedigree! thank you!
All the way from Ghana 🎉😊
nice and clear. easy to understand!
جزيت خيراً
Do u hv videos on how to solve all pedigrees
Best explanation
FDD 🕺 MSR 🕺 FDD 🕺 MSR 🎶 🎶 my latino head already making a choreography in my head lol
As a general pedigree structure/composition rule, aren't males always on the left and females are on the right in a couple that mates (ie:// example 1)
awesome video as usual
Wait! In the X linked recessive one the third punnet square had two homozygous recessive females. Thaat makes the female affected right?
Amazing 😻
Thank you so much 😊
Honestly it works !
Thank you so much! God bless you!
Make a t shirt with dirty med logo! I wanna buy!
Soo helpeful!
Awesome video! Thanks for the explanation:)
This video is MFly brilliant. 😅😅😅😅 luuuuuv it!!!!!
Brilliant!
Amazing
Perfect!!
this is so rad thank you
V nice explanation
what about the x^A Y, would that still be expressed? D:
What is the correct option?
Need more videos on genetics please!
Thankyou soo soooo sooo much ❤❤❤
thanks sir so easy lecture so so so thanks
I have a pedigree where there is an affected father x wt female producing an affected daughter and unaffected son. But my professor stated all cases, autosomal dominant+recessive and x-linked dominant and recessive work here....but how cold I check for rule 2 here?
Thank you
really helpful!
So does that mean, affected mother cannot pass the affected allele to their daughters?
She does, mother shows equal inheritance while the father by transferring Y chromosome to son and X one to her daughter shows unequal inheritance. That was just an example for you to determine the possible genotype of parents in a pedigree.
very good video 😁
Thank you so much for this video! It helped a lot! I wish I watched this video earlier
You are a godsend thank you
What about carriers !!
Is it affected mother or carrier mother for x linked recessive??
Thank u sir it's really useful heartly thank u sir
You are theee best i love u. Thank u sooo much
Dads are dominant over daughters X’s.
Mothers take their sons for Recess
Thanks
YOU REALLY HELPED ME ALLOT , THANK YOU SO MUCH
thank you!!
“Only Male from Uneffected parents” is also X linked Recessive???
what about X-linked dominant mothers?
amazing.
About question 1 that u put..wasn't that autosomal dominant inheritance ???
Freaking entry exams into med school were harder than the med school itself :D
Really?
thankyou
Thakyouuuuu❤❤❤
So if the allele is recessive and affected sons don't come from affected mothers, can we say based on that info that the disease is not X linked? Someone please help
because this goes against what m teacher taught me.
Thank u
Thank you 🫂
nice
Thankyouuuuu
Where are the explanation of next types
heaven sent
👍👍👍
it takes me 5 min to remember the diff between the circle and the square.
It's x linked dominant
👍🏿👍🏿👍🏿👍🏿
I LOVEEEEEEEEEEEEEEEEE YOU
love u bro
FDD: Father Daughter Dance
Sound died
❤❤❤❤2
Ily