Genome Editing with CRISPR-Cas9

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  • เผยแพร่เมื่อ 30 ก.ย. 2024
  • This animation depicts the CRISPR-Cas9 method for genome editing - a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at zlab.mit.edu .
    To learn more visit mcgovern.scienc...
    Images and footage courtesy of Sputnik Animation, the Broad Institute of MIT and Harvard, Justin Knight and pond5.

ความคิดเห็น • 1.6K

  • @alangerber3960
    @alangerber3960 3 ปีที่แล้ว +4

    You are trying to play God you are interrupting God,s creation the body of man and the temple of God so don't you will explain to Him one day what you did

    • @hugoeriksson6524
      @hugoeriksson6524 3 ปีที่แล้ว +1

      tell that to your kids who currently don't have polio because of advancements in biomedical science like this one.

    • @remg.4075
      @remg.4075 ปีที่แล้ว

      A myth doesn't stand a chance against science.

    • @alangerber3960
      @alangerber3960 ปีที่แล้ว

      @@remg.4075 You have been done in by satan

  • @adriennegallotta2890
    @adriennegallotta2890 3 ปีที่แล้ว +5

    Abominable

  • @adriennegallotta2890
    @adriennegallotta2890 3 ปีที่แล้ว +4

    You have no idea what you people have done

    • @FindLiberty
      @FindLiberty 3 ปีที่แล้ว

      Well, they thought they knew, but then it escaped and now we are still finding out just how bad it is...
      So far. It has not killed everyone, _yet._ Pray. Cheer up and sing along, search TH-cam for
      CRISPR-Cas9 ("Mr. Sandman" Parody) | A Capella Science (Lyrics clue: we got the Rattata)

  • @adriennegallotta2890
    @adriennegallotta2890 3 ปีที่แล้ว +4

    Disgusting

    • @millermike9917
      @millermike9917 3 ปีที่แล้ว

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  • @glenn3012
    @glenn3012 3 ปีที่แล้ว +5

    who is here for Graphene Oxide & Covid Jab research

    • @cain5423
      @cain5423 2 ปีที่แล้ว +1

      th-cam.com/video/Y7cwNQupH-g/w-d-xo.html

    • @dedetudor.
      @dedetudor. 2 ปีที่แล้ว

      🤣😅🤷🐊🦎🐍💉💦🙈🙉🙊💀🕵

  • @fatihkocibar2999
    @fatihkocibar2999 4 ปีที่แล้ว +278

    Who is here after the Nobel Prize :))

    • @Vivekguptasrk
      @Vivekguptasrk 4 ปีที่แล้ว +1

      Me

    • @sdyadavauri
      @sdyadavauri 4 ปีที่แล้ว +1

      Me

    • @ahmettoygunkarslgil1288
      @ahmettoygunkarslgil1288 4 ปีที่แล้ว

      Me

    • @monicamir
      @monicamir 4 ปีที่แล้ว +6

      This is fake.
      As fake as political science they teach at MIT.
      This kind of research is not made like this.
      Those people are lying.
      I don't think any of such research should be done.
      How would they edit DNA?
      They will kill the live being they try to edit the DNA.
      This company was probably started by George Church. Read his history. He's not a scientist.

    • @asmaasaad922
      @asmaasaad922 3 ปีที่แล้ว

      Me

  • @drawingjamaa9267
    @drawingjamaa9267 8 ปีที่แล้ว +127

    #makedragonsreal

  • @jahslioness7
    @jahslioness7 2 ปีที่แล้ว +6

    These people are the devil.

  • @azukarzuchastux8066
    @azukarzuchastux8066 2 ปีที่แล้ว +3

    John 3:16 KJV
    For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life.

    • @dedetudor.
      @dedetudor. 2 ปีที่แล้ว +1

      Azuka... Amen. These people may perish. Sadly.

  • @markgaming650
    @markgaming650 9 ปีที่แล้ว +321

    As a biology student: this is the best explanation for the fuction of CRISPR - cas
    thanks for enlightening me.

    • @Workaholic_06
      @Workaholic_06 3 ปีที่แล้ว +1

      Bro what are you doing now

    • @markisar1396
      @markisar1396 3 ปีที่แล้ว

      @@Workaholic_06 What do you mean?

    • @Workaholic_06
      @Workaholic_06 3 ปีที่แล้ว +1

      @@markisar1396 profession

    • @markisar1396
      @markisar1396 3 ปีที่แล้ว +4

      @@Workaholic_06 something totally different. Not related to biology. Biology was great to study. Knowing about life on a scientific level. But life is more than this for me.

    • @Workaholic_06
      @Workaholic_06 3 ปีที่แล้ว

      @@markisar1396 please tell me whats ur job

  • @rezamousavi8181
    @rezamousavi8181 4 ปีที่แล้ว +50

    And they say women didn't invent anything......

    • @UK-ou7tk
      @UK-ou7tk 6 หลายเดือนก่อน +10

      Lol who?

    • @KDR911KO
      @KDR911KO 5 หลายเดือนก่อน

      Yeah who besides those who are intelligent 😂

    • @JT-xb6zs
      @JT-xb6zs 3 หลายเดือนก่อน +10

      Why is this even a comment, has nothing to do with crispr, women invent stuff all the time. Keep your political and social views to a different video this is for education

    • @guest-cd7md
      @guest-cd7md 2 หลายเดือนก่อน +2

      this gender war trash makes me sigh

    • @Dansupreme
      @Dansupreme หลายเดือนก่อน

      @@guest-cd7mdsocial issues should be least of any one’s concerns. We have bigger things to worry about.

  • @dave-huston-dublin
    @dave-huston-dublin 3 ปีที่แล้ว +7

    Dangerous Times.

  • @Nickel2010
    @Nickel2010 3 ปีที่แล้ว +5

    Is this used in the Covid vaccine?

    • @jakeross21
      @jakeross21 3 ปีที่แล้ว +4

      YES look up the patent

  • @tetsugal
    @tetsugal 10 ปีที่แล้ว +657

    This is insane!, How come they can achieve this level of precision at such a tiny scale? It certainly looks like magic.

    • @pingubitches5304
      @pingubitches5304 9 ปีที่แล้ว +62

      +tetsugal
      It's just taking advantage of what nature has already made. The proteins involved in holding the segments of DNA in place and slicing it in precise places is what our body does 24/7. Inside our cells, these proteins are involved in keeping us alive. The enzymes drive chemical reactions, and essentially "cut and stick" things together. We've just learnt these processes in molecular biology / biochemistry well enough to be able to slightly manipulate what the body already does to favour a particular response (e.g against a particular virus or disease response). Evolution is a slow and often imprecise mechanism to improve our bodies. With the planning and learning capabilities of our own brains, we can manipulate what our bodies already have to perform specific functions which evolution hasn't caught up with yet... so we can use these techniques to treat or even cure diseases that have affected us and caused suffering for far too long.

    • @Helmet_Tester
      @Helmet_Tester 8 ปีที่แล้ว +18

      +Pingu Bitches Now if we can nail down all the 4-500 genes that divide out of control (Cancer) I think we may have the ability to make it a thing of the past.

    • @ChispyReddit
      @ChispyReddit 8 ปีที่แล้ว +50

      +Pingu Bitches What really blows my mind is that CRISPR is a biological technology that bacteria invented to fight viruses. We're basically learning from bacteria and are basically using alien technology for our own benefit.

    • @AtulKaushal7
      @AtulKaushal7 5 ปีที่แล้ว

      @tetsugal Certainly. :-)

    • @AtulKaushal7
      @AtulKaushal7 5 ปีที่แล้ว +5

      @@Helmet_Tester, yes but it will take another handful of decades. By 2050 we can expect it to fully develop.

  • @taghkrell
    @taghkrell 8 ปีที่แล้ว +318

    THIS reasearch and researchers should've won the nobel

    • @pbliable
      @pbliable 7 ปีที่แล้ว +7

      just like dynamite!! nice, VERY much the same!

    • @martinbuggard6672
      @martinbuggard6672 5 ปีที่แล้ว +17

      I actually think, from what my professor has told me, that the people who first really discovered crispr a decade or so ago were undergraduate students and when they stumbled across it their superiors were shocked to see the implications.

    • @DoodleSh1t
      @DoodleSh1t 5 ปีที่แล้ว +16

      they probably aren't women, trans, african, or jewish, so they will probably never be noticed.

    • @a.t.3192
      @a.t.3192 4 ปีที่แล้ว +34

      @@DoodleSh1t Are you dense? The top 5 countries with the most Nobel prize winners are all caucasian majority countries, and in all of Nobel history, only 7 LGBT+ have won. Now, I'm not saying that members of minority groups should be given favour, but it's really fucking dumb to suggest that straight white men have a reduced chance of winning. Go crawl back to 4chan, you red pill twat.

    • @rajeshchampia269
      @rajeshchampia269 4 ปีที่แล้ว

      @@martinbuggard6672 poo oil

  • @florenlebaron524
    @florenlebaron524 3 ปีที่แล้ว +2

    Unfortunately, this technology is used to harm humanity instead of helping. Ster•ilization.

  • @packetman
    @packetman 5 ปีที่แล้ว +47

    I was trying to understand what CRISPR is. It's really mind blowing that things like this are possible. Great explanation.

    • @philobetto5106
      @philobetto5106 2 ปีที่แล้ว +2

      Yep Imhotep will be appearing at Pomona college on gene editing

  • @adriennegallotta2890
    @adriennegallotta2890 3 ปีที่แล้ว +3

    Now when this mortal puts on immortality and this corruptible puts on The incorruptible then comes the end
    Death will be swallowed up in victory
    every single person that has decided to edit the human genes will reside in hellfire forever after
    You have paved your own way into perdition
    The Lord God will deal with you

  • @adriennegallotta2890
    @adriennegallotta2890 3 ปีที่แล้ว +6

    For the abomination of desolation has been set up

  • @kitskitt5412
    @kitskitt5412 2 ปีที่แล้ว +6

    Playing God never ends well.

    • @dedetudor.
      @dedetudor. 2 ปีที่แล้ว

      Kitskitt...
      Fools never learn.
      🕊MARANATHA🕊

  • @douglaspinsak1246
    @douglaspinsak1246 2 ปีที่แล้ว +4

    Does it occur to anybody that we should not be doing this?

    • @James-uu6xs
      @James-uu6xs 2 ปีที่แล้ว

      Jurassic Park? 😆

  • @hamzabendjedou8065
    @hamzabendjedou8065 3 ปีที่แล้ว +14

    Who is here from coronavirus vaccine

  • @gimoroemma
    @gimoroemma 2 ปีที่แล้ว +8

    These are in the mystery juice these folks want to push into us!

  • @tomlee6263
    @tomlee6263 3 ปีที่แล้ว +4

    It can also be used to cause disease...

  • @attackdamage7105
    @attackdamage7105 5 ปีที่แล้ว +230

    0:10
    Red blood cell: Am I a joke to you?

    • @ganibattlebeard
      @ganibattlebeard 5 ปีที่แล้ว +18

      tmw ur just a big protein

    • @sand8683
      @sand8683 4 ปีที่แล้ว +2

      @@ganibattlebeard hahaha

    • @Jerry_licious
      @Jerry_licious 4 ปีที่แล้ว

      RBC doesn't really count as a cell I think.

    • @jasondeller1818
      @jasondeller1818 4 ปีที่แล้ว +5

      @@Jerry_licious it has cell in its name you degenerate cow

    • @charlesritchet9949
      @charlesritchet9949 4 ปีที่แล้ว +4

      @@Jerry_licious rbc is red blood cell

  • @zarkoff45
    @zarkoff45 9 ปีที่แล้ว +46

    Wow! This is another science fiction dream/nightmare coming true.

    • @ricco3
      @ricco3 3 ปีที่แล้ว +1

      @@florenlebaron524 yeah right what kind of drugs are you smoking?

    • @Mark-Wilson
      @Mark-Wilson 3 ปีที่แล้ว +1

      @@florenlebaron524 lol weed? or what what did you take lol

    • @norbertfleck812
      @norbertfleck812 2 ปีที่แล้ว +1

      @Yousef Mohammed Mohammed Ali Ahmed This method also allows to create biological weapons which are beyond your worst nightmares.

  • @MrDario8
    @MrDario8 3 ปีที่แล้ว +3

    something tells me that it is a delayed fire bomb and a pandora's box with terrifying contents as a gift to a civilization with too weak ethics and the predominance of evil over good intentions...

  • @mikeoz4803
    @mikeoz4803 2 ปีที่แล้ว +2

    Frankenstein stuff.........it will be the end of what we define as a human

  • @teddayer6523
    @teddayer6523 5 ปีที่แล้ว +152

    I sincerely hope that Mr Crisper and Kasnine will get the Nobel Prize some day 😔

    • @user-xf6nk8so7y
      @user-xf6nk8so7y 4 ปีที่แล้ว +1

      Darius Diran *cas 9

    • @anarchy8968
      @anarchy8968 4 ปีที่แล้ว +7

      hopefully that's a joke...

    • @purplematter3779
      @purplematter3779 4 ปีที่แล้ว +17

      Anarchy must be some type of fool to even question whether that was a joke or not

    • @anarchy8968
      @anarchy8968 4 ปีที่แล้ว +3

      @@purplematter3779 that was my joke...

    • @user-xf6nk8so7y
      @user-xf6nk8so7y 4 ปีที่แล้ว +3

      Anarchy fuck I got r/whooooshed

  • @oljimeagle
    @oljimeagle 2 ปีที่แล้ว +6

    Yes .... This will definitely not be used for evil...

  • @helmischlaman4755
    @helmischlaman4755 8 ปีที่แล้ว +43

    A great lecture every student in life sciences, biology and medicine should see.

    • @ONIBUSENTORNO
      @ONIBUSENTORNO 11 หลายเดือนก่อน

      th-cam.com/video/tFQWtgpoIwU/w-d-xo.html

  • @KristysEdits
    @KristysEdits 4 ปีที่แล้ว +147

    It has been 6 years.

    • @annaoaulinovna
      @annaoaulinovna 4 ปีที่แล้ว +48

      their product is covid-19

    • @Gerdaldfighterkid
      @Gerdaldfighterkid 3 ปีที่แล้ว +14

      Their vaccines are this.

    • @666Metalbassist
      @666Metalbassist 3 ปีที่แล้ว +20

      @@annaoaulinovna that is wildly false

    • @666Metalbassist
      @666Metalbassist 3 ปีที่แล้ว +21

      @@gaming4K how does it change your DNA lmfao? Do you even know what mRNA is?

    • @gaming4K
      @gaming4K 3 ปีที่แล้ว +1

      @@666Metalbassist Why don't you watch his video? Than you will see what he is talking about...

  • @leslierogers2447
    @leslierogers2447 9 ปีที่แล้ว +487

    My daughter suffers from a Rasopathy de novo mutation syndrome. I listen to people discuss this as if it is some ethereal thing and on a very academic level. I watch children suffer and die. We need to move ahead with non human trials and finally human trials. It is so tantalizingly frustrating to know that there is a knock out for my daughters specific gene already and we are just waiting on it to be tested. Go geneticists go.

    • @FootysMaXeD
      @FootysMaXeD 9 ปีที่แล้ว +36

      It isn't perfect because there are practical limitations to everything of course. From what I know so far, there is some inaccuracy in targeting the correct sequence.

    • @leslierogers2447
      @leslierogers2447 9 ปีที่แล้ว +25

      Footsy, the Chinese, not that I agree, have already declared they have used it in human embryos to a success rate of about 67%. I think it is way too early for that kind of experimentation, but I also hear pull back the reigns way too much when I hear people discuss this. I know many children that cannot wait, like we did on stem cells, for our collective moral palate to warm to the idea of CRISPR. The genie is out of the bottle, and I read about targeting improvement nearly weekly from Santa Cruz biotech. We have the medical ability to keep many children alive now, but it destroys families economically in the United States social services are constantly being cut...I sat in a children's hospital for 4 months in Oregon and watched child after child get signed over to the state. If there is a way forward to help some of these children and adults not lead a life of suffering then we need to dive in full bore. I also feel there is potential in learning about epigenetics control of gene expression. I realize we aren't there yet, but now is the time to redouble our efforts not hit pause.

    • @marin427
      @marin427 9 ปีที่แล้ว +76

      +Leslie Rogers i am sorry, but if we bypass the testing safeguards we risk blurring the line between helping and harming. more budget is needed to speed things instead.

    • @FootysMaXeD
      @FootysMaXeD 9 ปีที่แล้ว +22

      +Leslie Rogers Adult animals have a lot of cells, which makes it hard to genetically modify all of them (one option they're using is viral vectors). If you perform the modification in a single-cell life (i.e. an egg cell), then all the progeny of that cell will also be similarly modified/fixed. Another problem is that cutting the DNA often results in random sequences of DNA being added, instead of the sequence that you are trying to stick in there. I think these and other possible side effects should be studied longer before unethically using this as a clinical trial.

    • @lactobacillusacidophilus
      @lactobacillusacidophilus 8 ปีที่แล้ว +17

      +Leslie Rogers Unfortunately couple of assholes already patented this technology which is a naturally evolved system. They seek to "milk" this system as much as possible first. Such acts slow down new inventions and prevent others to make it better.

  • @theantireaper
    @theantireaper 8 ปีที่แล้ว +41

    So crispr is like sql injection.

    • @vmikeyboi323
      @vmikeyboi323 8 ปีที่แล้ว +2

      haha this gave me a good laugh, id like to think so, buts a postive thing, unlike sql injection

    • @FutureAIDev2015
      @FutureAIDev2015 7 ปีที่แล้ว

      Hehe I guess that's an accurate analogy!

  • @TheDavidlloydjones
    @TheDavidlloydjones 6 ปีที่แล้ว +127

    Congratulations to the people responsible for this piece of video. Well written, brilliantly animated, and narrated by a speaker who should serve as an example to every speaker across all topics on TH-cam!
    Are there Oscars or Guggenheims for this sort of educational work yet? We have here a nominee...

    • @hobbes5043
      @hobbes5043 2 ปีที่แล้ว +3

      Every video on TH-cam should be produced as if it's an explanation by The Massachusetts Institute of Technology of the most important biological discovery of the 21st century

    • @dhivyar6501
      @dhivyar6501 ปีที่แล้ว

      A

    • @ONIBUSENTORNO
      @ONIBUSENTORNO 11 หลายเดือนก่อน

      th-cam.com/video/tFQWtgpoIwU/w-d-xo.html

  • @ultravidz
    @ultravidz 8 ปีที่แล้ว +303

    The technology is here! Now let us refrain from doing anything useful with it for 30+ years.

    • @Nicistarful
      @Nicistarful 8 ปีที่แล้ว +65

      +AlphaOmega Or better! Let the people who go and say: "Oi, don't do that it's ethically not correct, waah" Rule over everything! Seriously though instead of doing good we're just biting ourselves in the arse...

    • @masterchef1837
      @masterchef1837 8 ปีที่แล้ว +9

      +The Renegade Programmer Doctors thought the same about Thalidomide

    • @robertmcanany6397
      @robertmcanany6397 8 ปีที่แล้ว +39

      +The Renegade Programmer I can understand your sentiment here, but let's be honest. There truly are some people out there that would fall into the "mad scientist" category. If there aren't tight controls on this type of technology, its potential for abuse/misuse is staggering. Instead of repairing damaged/mutated DNA in humans, what's to stop some black-book government program from adding things to the human genome that doesn't belong there? Sci-fi movies about genetically modified super soldiers become a reality.
      I agree that the trials portion of these types of technologies can seem to take far too long, but to simply remove those restrictions may end up causing more harm that good.

    • @bighands69
      @bighands69 8 ปีที่แล้ว +3

      Who gets to decide what is ethical and what is not ethical. And who gets to decide what is right to use these technologies on.
      If there was this approach to vaccines or antibiotics they would never have been used and it may have been the 1960s or 70s before they got implemented.
      It is OK to say we must be careful but what is careful. Any research can in effect cause massive problems.

    • @joshuavallejos3173
      @joshuavallejos3173 8 ปีที่แล้ว +4

      My brother suggests that depopulation is the solution to the worlds current issues. obviously mankind has reached a stage where depopulation will bring no form of ultimate solution. we are at the verge of the next human evolution. and depopulating humanity will be like killing dogs off it will be so irrelevant if our children are genetically being modified to be something off form the current standard of what is considered human kind today. Robert what do you think? I believe reeducating people and developing anew form of sustainable society is the only way to press humanity forward. Government has to change, peoples way of thinking has to change and a new form of energy.

  • @dannykendra2289
    @dannykendra2289 9 ปีที่แล้ว +46

    lets go for it. full speed ahead to ridding the world of genetic diseases. we could rid humans of horrible predisopsitions such as obesity, degenerative diseases ms cancers. this could be the new vaccines!

    • @seanarmstrong1156
      @seanarmstrong1156 9 ปีที่แล้ว +13

      +Danny Kendra it could also mean human engineering to produce superior humans...humans with higher IQ, better eyesight, better athleticism, taller height...etc etc...
      and u know what's next? Companies are going to charge high price for it. And only the rich people can afford.
      And the poor are going to totally riot over this...and before u know it...the world is going to go into chaos...

    • @seanarmstrong1156
      @seanarmstrong1156 9 ปีที่แล้ว +1

      ***** i largely agree. I think we should focus our research only on curing diseases affecting children and babies. I personally think if someone already live to the age of 75 and got cancer, then ti's meant to be. Time to go. If I live to 75, i would be happy to die.

    • @dannykendra2289
      @dannykendra2289 9 ปีที่แล้ว +4

      what i believe is that we would be able to contain genetic engineering of the human genome to be strictly medical for preventing disease and dead conditions. it would be in the hands of the medical community which is very good about enforcing its own regulations. i think it's worth it trying.

    • @dannyg1392
      @dannyg1392 9 ปีที่แล้ว +2

      +Sean Armstrong Things are rarely so extreme. Try to think of all the good it will do.

    • @seanarmstrong1156
      @seanarmstrong1156 9 ปีที่แล้ว +8

      Daniella G i agree. I just want people to be aware of the dangers and be ready to support the legislation of new laws that we would need to properly regulate this technology.
      It's like gene patent. Back in 1970s, people were patenting genes like they own it. And then there was this whole huge debate about whether or not a company can legally own a gene or not. And after more than 15 years of debate, we finally decide "no, you cannot patent a gene".
      We're going to need new laws to regulate CRISPR technology to prevent bad exploitation.

  • @miaclark1808
    @miaclark1808 9 ปีที่แล้ว +2

    It's a nightmare. The human genome operates perfectly in it's entirety. Only in it's individual manifestation does it seem to have a lot of imperfection. It's natures way of trial and error. Genetic editing is a horror. It was done during the days of Noah when the powers that be wiped out all of those who were not perfect in their generations as Noah and his wife were. People should protest this nightmare like Baltimore.

  • @saved1580
    @saved1580 6 ปีที่แล้ว +4

    This is the omen of Mystery Babylon final days. To blemish the original genome in the pretext of cure. Good for you, you are fulfilling prophecy written thousands of years ago.

  • @stritax9478
    @stritax9478 2 ปีที่แล้ว +2

    Why do I feel like this is the end of human beings

  • @deidresagonda9940
    @deidresagonda9940 3 ปีที่แล้ว +3

    Ascribe to the LORD the glory due His name

    • @dedetudor.
      @dedetudor. 2 ปีที่แล้ว

      Deirdre... I do! 🙏🕊
      What a shock these godless individuals will have.
      A bad shock.

  • @AhmadKhalifAqilSyafiq
    @AhmadKhalifAqilSyafiq 3 ปีที่แล้ว +2

    Is the CRISPR method can be used to create Covid-19 vaccine?

    • @jrf7066
      @jrf7066 3 ปีที่แล้ว +2

      I believe so. Psychopaths not telling us that detail.

  • @abbedidriss5189
    @abbedidriss5189 9 ปีที่แล้ว +88

    Gattaca anyone

  • @Clarkofkrypton
    @Clarkofkrypton 9 ปีที่แล้ว +14

    Spider Man Becomes Reality with this technology

    • @aimanbacha
      @aimanbacha 9 ปีที่แล้ว +1

      +Clark Anderson the naughty professor becomes real

    • @NightfallShadow
      @NightfallShadow 7 ปีที่แล้ว

      you mean the nutty?

  • @jonlevitt7135
    @jonlevitt7135 9 ปีที่แล้ว +6

    Side effects may include zombieism.

  • @LovinFFX2
    @LovinFFX2 ปีที่แล้ว +2

    Don’t let them change you from God’s image. This tech is in the c-19 shots.

    • @Etrancical
      @Etrancical 11 หลายเดือนก่อน

      Photoshop and deepfakes let us alter how we perceive reality, so what weight does "god's image" truly hold?
      And if "god's image" is so perfect, then why are so many babies born with birth defects, genetic illnesses, and compromised immunities? Why do so many little kids get cancer? No god that willingly creates unjust pain is a god worth worshipping.
      As a college biology student, my sole purpose in life is to advance this research and destroy the image of such a bastard god

  • @chrish4938
    @chrish4938 5 ปีที่แล้ว +31

    One of the best informational videos on CRISPR CAS-9 genome editing that is out there! Keep up the good work!

  • @iloveamerica1966
    @iloveamerica1966 4 ปีที่แล้ว +2

    Scary because we all know that there are unscrupulous people out there, as well people with ulterior motives.

  • @drawingjamaa9267
    @drawingjamaa9267 8 ปีที่แล้ว +31

    what i will do with this
    make dragons
    make unicorns
    make two legged gazelles
    make flying naked mole rats
    make pokemon

    • @jainamrp
      @jainamrp 4 ปีที่แล้ว

      That is why they banned.

    • @hallowsalways4584
      @hallowsalways4584 4 ปีที่แล้ว +5

      And because of people like you this treatment can’t be taken seriously and those who could benifits from it would miss out

    • @NotLikeUs17
      @NotLikeUs17 3 ปีที่แล้ว

      @@jainamrp they’re about to make a cure for HIV with this technology now.

  • @leonardolimacamara6670
    @leonardolimacamara6670 10 หลายเดือนก่อน +1

    Yeah, CRISPR is incredible, but what happens when deoxyribonucleic acid is cut and is not replaced? An cancer i think. So even with all the possibilities it can give us, there is an big risk involved. Anyway, the video is awesome!

  • @leecurtis368
    @leecurtis368 7 ปีที่แล้ว +63

    This is an amazing and powerful tool, the possibilities are endless, but when the weapon developers get hold of it, and they always do, it's frightening to think of what they will think of

  • @otakusangelo
    @otakusangelo 7 หลายเดือนก่อน +1

    it so exciting one of my dreams is to work with such researchers, I want to revolutionise the world

  • @tonisoler2064
    @tonisoler2064 8 ปีที่แล้ว +3

    Well, against we are talking about some science fiction here. Sure is a start. But we have to face that we can't control with enough precision that modifications. We just have to look over the GMO on the food we eat, and how those modifications lead to an increasing risk of some diseases indirectly.
    Personally I think that what is explained on this video is a great idea, but I also think that we have to put serious regulations to that kind of studies, because is incredbily easy to have side efects with those modifications, and I don't want a world where every disease is caused by GMO's first, and then cured in the same way, leading again, to some undesired side effects that can have a negative impact in our lives.

  • @pansenberlin
    @pansenberlin 8 ปีที่แล้ว +2

    Wrong in the first sentence, not every cell has a full genom, get your shit straight !
    And what about the length of the RNA used foir this method, you are talking about the whole genom in human, there must be a pretty long RNA to be totaly assured that it cuts the right Virus DNA, because we have a lot of that inside of us, the propability of cutting other Genes seems a bit to high with this animation

  • @j.sumeet
    @j.sumeet 4 ปีที่แล้ว +5

    Anyone after Nobel Prize in chemistry 2020 ?

  • @chefbillybaroo2056
    @chefbillybaroo2056 3 ปีที่แล้ว +3

    You should be careful you never know a tiny change at that level could be a monster exchange on our level!

    • @hugoeriksson6524
      @hugoeriksson6524 3 ปีที่แล้ว

      definitely, that's the point! people have had their sight restored with this technology, all by changing a few little chemical letters

  • @Clifford03
    @Clifford03 2 ปีที่แล้ว +3

    We are indeed playing God now

  • @gobofraggel7383
    @gobofraggel7383 4 ปีที่แล้ว +41

    "Brother to Demons, Brother to Gods" - I read this book many years ago. It's the story of men who use genetics to create men superior to themselves and ultimately Stargods who turn on them. We are headed in that direction.

    • @GASHAM78
      @GASHAM78 3 ปีที่แล้ว +10

      The jabs use CRISPR

    • @ansiedelport3087
      @ansiedelport3087 3 ปีที่แล้ว +2

      God help us forgive us this worldly sins

    • @trashnaut
      @trashnaut 2 ปีที่แล้ว

      Nice.

    • @boss_niko
      @boss_niko 2 ปีที่แล้ว +1

      Why do you always think negative man?

    • @mauricewalker5920
      @mauricewalker5920 2 ปีที่แล้ว +1

      Genesis 6:4

  • @BH-ip6ds
    @BH-ip6ds 9 ปีที่แล้ว +3

    I am awed by this but also afraid. Where will we be? Somewhere that doesn't look anything like where we are now. It might not be that difficult to explain the internet to someone born in the middle of the 20th century. It is still something that wasn't a predictable outcome - something that we're still trying to grasp.
    What will the world look like when this technology is commonplace? Unfortunately, it makes me think of the Fermi paradox.

    • @Stringbean421
      @Stringbean421 9 ปีที่แล้ว +2

      +Ben Hebert
      Don't worry about it. We'll be long dead by the time the human super race is common place.

    • @BH-ip6ds
      @BH-ip6ds 9 ปีที่แล้ว

      Nunsweepit421
      You're almost certainly correct. I'd love to know though...

    • @Stringbean421
      @Stringbean421 9 ปีที่แล้ว +1

      +Ben Hebert
      Yea,..me too. Remember that film called Gattaca made in 1997? One of my all-time favourite films. Sci-fi becoming science-fact!

    • @donkeyface123
      @donkeyface123 9 ปีที่แล้ว

      +Ben Hebert Care to explain the fermi paradox. i am interested

    • @BH-ip6ds
      @BH-ip6ds 9 ปีที่แล้ว

      +donkeyface123
      the Fermi paradox, very simply put, is the application of conservative assumptions about the likelihood of intelligent life in our galaxy contrasted with the observation that we haven't found any evidence of it. One of the disturbing explanations for why this might be is that intelligent life always destroys itself with the technology it eventually employs.

  • @tonyotis1
    @tonyotis1 8 ปีที่แล้ว +7

    If a person with an early stages of cancer, is it possible to scan DNA for cells that maybe developing cancer, repair the DNA into a health cells.

    • @royalrangew8
      @royalrangew8 8 ปีที่แล้ว +1

      I believe a CRISPR trial will be underway later this year, but the technique won't be used on cancer cells. They will be used on healthy cells belonging to the immune system as a form of immunotherapy - the cells will be modified to effectively recognise cancerous cells in a patient and ultimately destroy them.

  • @benjamiah
    @benjamiah 5 ปีที่แล้ว +24

    The possible misuse of this research in the wrong hands is scary

    • @stacylangford8015
      @stacylangford8015 3 ปีที่แล้ว +4

      What hands could possibly be trusted?

    • @Dasani_water_drinker
      @Dasani_water_drinker 3 ปีที่แล้ว +2

      @@stacylangford8015 i can't. I didn't believe science was against God but now i know it is.

    • @user-ko3te7oy6d
      @user-ko3te7oy6d 3 ปีที่แล้ว +3

      @@Dasani_water_drinkerOh boy

    • @bakublader1999
      @bakublader1999 3 ปีที่แล้ว +2

      @@Dasani_water_drinker So you say something is against God when you don't understand how it works?

    • @Dasani_water_drinker
      @Dasani_water_drinker 3 ปีที่แล้ว +2

      @@bakublader1999 you don't know what i understand. You're the who doesn't- when you create science that can basically take what was God's right to make, then you are against him.

  • @galod.8423
    @galod.8423 4 ปีที่แล้ว +2

    Who is here because of biochemistry class?

    • @ARY-g7k
      @ARY-g7k 3 ปีที่แล้ว

      Biopharmacy here

  • @clawofthefallen
    @clawofthefallen 5 ปีที่แล้ว +9

    From this moment on, everything has changed.

  • @planetgaia7974
    @planetgaia7974 2 ปีที่แล้ว +1

    sounds like some sort of hidden agenda at play here

  • @ashwanikumar8105
    @ashwanikumar8105 4 ปีที่แล้ว +4

    Thank you mam ❤️ to make me clear this biotechnology method practically !
    But my one doubt is - will it be really possible to Tampere or destroy any inheridery diseases successfully .. I mean in general medical science like colour blindness what can't be cured at all ?

  • @teresaoverholt6253
    @teresaoverholt6253 ปีที่แล้ว +2

    This is insanity 😳

  • @JS-ns8dr
    @JS-ns8dr 5 ปีที่แล้ว +9

    Watching this before an essay due tmr😅

  • @carolteng00
    @carolteng00 3 ปีที่แล้ว +1

    it's 6 billion letters of DNA, not 3 billion ...

  • @saxlaxdm10
    @saxlaxdm10 8 ปีที่แล้ว +108

    I worked in a lab thats helping perfect and understand CRISPR and this video literally makes me cry. its one of the most wonderful things we've ever accomplished. This changes the world in so many ways. But at the same time its on of the most ethically odd things we've ever encountered. Also don't be fooled, were still a decade away from editing your genome at the doctor's office. Or really doing anything at all.

    • @PureStew750
      @PureStew750 8 ปีที่แล้ว +4

      +saxlaxdm10 That's so cool and I completely agree with how long we are before being able to do anything with the crispr system. Some people don't understand that the project is still in it's fairly early stages. Just doing a little research on the topic can go a long way. May I also ask, what area of the project are you responsible for?

    • @nikcile4034
      @nikcile4034 7 ปีที่แล้ว +1

      saxlaxdm10 how do I synthesize cas9?

    • @Po0pypoopy
      @Po0pypoopy 6 ปีที่แล้ว +6

      fuck you

    • @lacedhexes
      @lacedhexes 5 ปีที่แล้ว +9

      Aaand now we have CRISPR babies in China. How do you guys feel about that?

    • @codycagle3241
      @codycagle3241 4 ปีที่แล้ว +9

      @Sonia IS The doc messed up. The gene they deleted in those children is linked to higher mortality rates from influenza. Shortsightedness from scientists looking to be famous can potentially make those humans very unhappy. Short term goals vs long term effects.

  • @umaradamu8679
    @umaradamu8679 2 ปีที่แล้ว +6

    am not a student of this sort, but am a very huge fan of such development in science, thanks for the update.

  • @dLimboStick
    @dLimboStick 8 ปีที่แล้ว +62

    There's no way we could ever fuck this up. Never!

    • @sbellaharris
      @sbellaharris 8 ปีที่แล้ว +2

      We do, we always do. We have monetary system and the patenting system that came from it. They are fighting for the patent, people who clean our streets will never be able to afford it.

    • @elladreames6958
      @elladreames6958 7 ปีที่แล้ว

      dLimboStick practice makes perfect.

    • @Estoniran
      @Estoniran 7 ปีที่แล้ว +6

      if it weren't for the "monetary system", which I think you are using the mean the free market, there would be no incentive for companies to develop new technologies. Even worse though, without a free market there would be no competition and prices would remain high. Look at your smartphone, when it was first being developed it likely costed over a hundred thousand dollars, and now can be bought for a couple hundred

    • @MishaFlower
      @MishaFlower 7 ปีที่แล้ว +2

      +Estoniran
      Do people really think there is such a thing as a system where there is nothing but rainbows and sharing?

    • @yanadoodle6065
      @yanadoodle6065 6 ปีที่แล้ว

      well... we already did that...

  • @venlajunnikkala2938
    @venlajunnikkala2938 3 ปีที่แล้ว +1

    No, I definitely don't have a biology exam in 40 minutes, why?

  • @starryvoyage
    @starryvoyage 5 ปีที่แล้ว +4

    Zombie outbreak is getting closer than ever before

  • @robplatt7138
    @robplatt7138 2 ปีที่แล้ว +1

    The possibility to benefit humanity to a degree previously incomprehensible.
    ( And tragically, the complete antithesis will also most certainly manifest…inevitable.)

  • @josueguzman9106
    @josueguzman9106 7 ปีที่แล้ว +10

    biotechnology ❤👌❤👌❤👌

  • @malleshaiahveeranna2659
    @malleshaiahveeranna2659 4 ปีที่แล้ว +1

    Why this can't be used to treat CORONA virus

  • @neelammaleen1
    @neelammaleen1 ปีที่แล้ว +3

    BEAUTIFULLY ANIMATED!!! Never thought I'd fall in love with such a video. Loved it!

  • @kirkwallace-cy7fu
    @kirkwallace-cy7fu หลายเดือนก่อน +1

    Is it that man is playing God now, be warned, this is messing with God's business, know where all of this is going, human has now become a specimen

  • @marjanm.hashemi5757
    @marjanm.hashemi5757 8 ปีที่แล้ว +13

    perfect explanation

  • @cuianomundo
    @cuianomundo ปีที่แล้ว +1

    Doing wonders in the covid shots ☠☠☠

  • @maxdoubt5219
    @maxdoubt5219 8 ปีที่แล้ว +29

    We got our baby home but she clashed with the carpet so we had her crispr'ed a little darker...

    • @rchrdpnccruz8432
      @rchrdpnccruz8432 7 ปีที่แล้ว

      Deacon Verter lmfao

    • @maxdoubt5219
      @maxdoubt5219 7 ปีที่แล้ว +6

      I wanted a dog, they gave me a cat
      but now I can alter this pet that I got
      CRISPR is here, and thank God for that!
      Adios Mittens, soon you'll be Spot!

    • @nikcile4034
      @nikcile4034 7 ปีที่แล้ว +3

      Deacon Verter i think the regulations on it should be that you can only edit human DNA with consent from the person who has it and have it so only genetic diseases can be edited out for baby's and unborn children that way we don't end up with designer babys

    • @iloveamerica1966
      @iloveamerica1966 4 ปีที่แล้ว +1

      My bacon never cooks right, so I had my vet make my pigs a little CRISPR.

  • @rahul_bali
    @rahul_bali 3 ปีที่แล้ว +1

    Dont imagine,
    god made perfect humans with zero editing required.
    Proof. We have been alive for million of years now, still growing.
    Good day :-)

  • @MFJL760
    @MFJL760 7 ปีที่แล้ว +4

    Can crispr be used to edit the DNA of cancer cells to make them self destruct?

    • @jyotsnakhithani2241
      @jyotsnakhithani2241 5 ปีที่แล้ว +4

      yes but it's impossible for an adult as each and every malignant cell has to be genetically edited

  • @Franaflyby
    @Franaflyby 6 ปีที่แล้ว +1

    God says that we are ...Fearfully and wonderfully made so why would we change that ?

    • @JoyDaz00
      @JoyDaz00 4 ปีที่แล้ว +1

      Amen, abbide in JESUS' Word, that's all a man and woman need. The whole duty of a man is to fear God and do His commandments(including the moral laws only from the OT and not Moses' laws; and the NT Gospel commandments (John 3:5 -> Acts 2:38)

    • @francestod.tandocjr4092
      @francestod.tandocjr4092 3 ปีที่แล้ว

      2 years of rest, and maybe you realized some of us aren't genetically healthy.

  • @persephone2706
    @persephone2706 2 ปีที่แล้ว +13

    The animation is fantastic but I always wonder what it truly looks like... I bet it would be life changing if there was any way to be able to witness the process with one's own eyes, or merely witnessing DNA itself. Even knowing how life occurs and what constitutes it, it's still all so undeniably wondrous.
    🧬☄🌍

    • @Matetas-gv8lj
      @Matetas-gv8lj 2 ปีที่แล้ว +1

      you see the video of atpase in action? INSANE th-cam.com/video/QeHCAFKaWM8/w-d-xo.html its the gamma subunit rotating, producing the energy of life ATP

    • @TS-uh3ig
      @TS-uh3ig ปีที่แล้ว +2

      Elohim - Jesus - Wonderful Creator of all. He is life changing and you can witness Him and have a relationship with your Creator yourself.

    • @MichaelBrown-hc6iu
      @MichaelBrown-hc6iu 5 หลายเดือนก่อน

      Well crispr cas 9 is smaller than the wavelength of visible light, so it literally "looks" like nothing; it cant be seen.
      But I CAN tell you what DNA looks like. Its very gloopy, gluggy, like really thick mucus or slime. If you stick a glass hook into the testube and draw the DNA out it forms very long strings, so not like normal slime, its like . . . stringy slime. The molecules are extremely long so can be drawn out a long way.

  • @cambeenie
    @cambeenie 2 ปีที่แล้ว +1

    anybody here from meow wolf?

  • @edwardbayley3799
    @edwardbayley3799 8 ปีที่แล้ว +3

    This video is very well done! No need to dwell too much on how the technology could be abused. Science is very good at self-policing. Simply put, mad scientists do not receive funding.

    • @Hfajardo97
      @Hfajardo97 8 ปีที่แล้ว +2

      +Edward Bayley That's certainly not true. Oppenheimer was a scientist, look at the massacre his nukes committed. Also look at any of our other weapons of destruction, some scientists are behind a great deal of them. This stuff is cool but I support people who ensure that we don't carelessly get ahead of our ambitions because it forces the people behind scientific advancements to ensure their creations work well and have less unintended negative side effects.

    • @edwardbayley3799
      @edwardbayley3799 8 ปีที่แล้ว +3

      +Hfajardo97 That is a good point. Strange that we live in a world in which the govt eagerly funds technologies explicitly intended to kill people, but will shy from supporting embryonic research if there is any worry it could be used to modify humans, regardless of intent. But I do still think the research in biology and medicine is well policed by the scientific community.

  • @geoffreyhewitt3903
    @geoffreyhewitt3903 3 ปีที่แล้ว +1

    so I have a mutation after my DNA was sequenced almost 10 years ago ; it kills family members after 5 years terrible

  • @AdventInnovative
    @AdventInnovative 8 ปีที่แล้ว +19

    This is the pinnacle of medical technology. It can fix anything..

    • @JoyDaz00
      @JoyDaz00 4 ปีที่แล้ว +5

      It cannot save your soul. Seek JESUS in His Word, until it's too late.

    • @Mark-Wilson
      @Mark-Wilson 3 ปีที่แล้ว +1

      @@JoyDaz00 the soul is not real we can tehcncialyl make someone with diffrent mental disabilities or abilities that slike cotnrolling soul if it was true then how do the soul work how does it form stop coming tos cientific videos with religious idiocy grow up anybody witht ruth in their suername usualyl is pretty dumb and far froma ctualt ruth

    • @Mark-Wilson
      @Mark-Wilson 3 ปีที่แล้ว +1

      @@chelee9261 ? lose what?? what does that have tod o with jesus this is revoltuinoary tehcnolgoy that can fix all medical usse sone day evne cancer or aging my dude this is the future

  • @christopherlucchesi2205
    @christopherlucchesi2205 2 ปีที่แล้ว +2

    I hope this is employed in gene therapy soon. I have a genetic disease that will eventually kill my kidney and to hear that it can be fixed is wonderful. All that needs to be done is it being given the green light

    • @boss_niko
      @boss_niko 2 ปีที่แล้ว

      i just hope this can end that fucking disease call neurofibromatosis. May be I wont be alive long enough to see that happening. This disease just ruined my life. FUCKKKK. Everyone deserves to live their life to the fullest. So many lives will be changed forever. It will feel like getting a new life for all of us who are suffering from genetic disorder.

  • @tejas1205
    @tejas1205 7 ปีที่แล้ว +19

    Brave new world we are living in

  • @mmenendez93yj
    @mmenendez93yj 3 ปีที่แล้ว +1

    Who determines what "flaws" are? Plenty of people who have disabilities and proud of who they are.

    • @maribethquito8409
      @maribethquito8409 2 ปีที่แล้ว

      Genetic diseases

    • @mmenendez93yj
      @mmenendez93yj 2 ปีที่แล้ว

      @ωγυγος Αρχων that's obvious. Anyone can say whatever they want if it seems to be beneficial. We still drink fluoride lol. We still brush our teeth with it. We still wash our bodies in it. We still use products that are possibly tied to cancer. The point of my question was who determines whether someone receives the treatment or not? Is it the govt? Is it medical doctors? Is it the people who suffer from these genetic disorders? But another thing... I don't think they would intentionally give them something that would change something else. If anything the reaction would be a side effect. Changing one thing does not actually change one thing. Bodily functions are systems that work with and for each other. With mechanical things you can modify something and the rest of the car will operate. But the body is completely different.

  • @CatarineausArmory
    @CatarineausArmory 9 ปีที่แล้ว +19

    Just what we need. The return of the nephilim.

    • @ArthurArktos
      @ArthurArktos 8 ปีที่แล้ว +3

      +Jon way no.

    • @PercyJenkinsLLC
      @PercyJenkinsLLC 8 ปีที่แล้ว +5

      +Jon way
      yes indeed. as were the days of noah so shall be the days of the coming of the Son of man

    • @HALEYBLUD
      @HALEYBLUD 6 ปีที่แล้ว +1

      mechnokie blood most diseases are man made tho

  • @iloveamerica1966
    @iloveamerica1966 4 ปีที่แล้ว +1

    My bacon never cooks right.
    CAS 9 makes the proteins too tight.
    So I asked my vet
    if he would let
    my swine get a little CRISPR.
    (My first quasi limerick- line 5 FAIL. Maybe I can do a little recombinant splicing.)
    My bacon never cooks right.
    CAS 9 makes the proteins too tight.
    So I asked my vet
    if he could get
    my swine a little CRISPR.

    • @dedetudor.
      @dedetudor. 2 ปีที่แล้ว

      😅😅🤣🤷

  • @roberthelm41
    @roberthelm41 8 ปีที่แล้ว +7

    Fake! Almost 300,000 views and there are only 7,000 people on earth look it up

  • @crimsom13
    @crimsom13 2 ปีที่แล้ว +1

    Meow wolf Denver brought me here

  • @amontucker6995
    @amontucker6995 8 ปีที่แล้ว +15

    I want Albert Einstein's DNA, and make me taller. Cool thanks

    • @tharebels4072
      @tharebels4072 8 ปีที่แล้ว +1

      Please don't be fooled! Einstein was a freemason, just as Neil DeGrasse, Tom Hanks and so many other 'famous' ppl. Welcome to flath earth (Pizza Planet).

    • @leonqarawaniqarawani8709
      @leonqarawaniqarawani8709 4 ปีที่แล้ว +1

      tha rebels wtf?

  • @aribamanjudevi3368
    @aribamanjudevi3368 4 ปีที่แล้ว +1

    I hope we discovered every DNA s... Even those that r very similar to that of the virus.... Otherwise if it targeted similar DNA it may create chaos.... I mean discovery is never ending n, consciousness /universe is ever expanding... We hunt even discovered the whole subconscious mind fully to make it part of the conscious mind... Good luck 🐞🍀

  • @PitoVH
    @PitoVH 9 ปีที่แล้ว +10

    Good job I can't wait for 2020....

    • @tdub6542
      @tdub6542 6 ปีที่แล้ว +6

      2020 is near and nothing seems to happen.

    • @Hana-wx8gz
      @Hana-wx8gz 4 ปีที่แล้ว

      @@tdub6542 Now is even closer haha

    • @Jebblegee
      @Jebblegee 4 ปีที่แล้ว +2

      its 2020 and things seem even shittier :(

    • @danl.4743
      @danl.4743 4 ปีที่แล้ว

      @@tdub6542 And they have just used this to try fixing a child's blindness. How 'bout that!

    • @bitcoin4065
      @bitcoin4065 3 ปีที่แล้ว +1

      Pito how did you know?

  • @Margoth195
    @Margoth195 6 ปีที่แล้ว +2

    The first statement of this video is dead wrong! not every cell in our bodies contains a copy of our DNA. Most of the cells in a human body are Bacteria and so don't have eukaryotic genomes thus not human DNA (note. some bacteria may have segments of human DNA in some bacteria). Not to mention Mature Red Blood cells don't have DNA either. This may seem nit picky but it is an important detail.

    • @dannywhite132
      @dannywhite132 5 ปีที่แล้ว

      technically (since we are nit picking) bacteria are not inside our body since they mainly reside in the intestines which is lines with epithelial tissue i.e the outside of our body. its just that we have a hole going through the body. what you say about red blood cells is correct but doesnt really matter for the sake of the video