SHERLOCK: A CRISPR Tool to Detect Disease

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  • เผยแพร่เมื่อ 3 ส.ค. 2024
  • This animation depicts how Cas13 -- a CRISPR-associated protein -- may be adapted to detect human disease. This new diagnostic tool, called SHERLOCK, targets RNA (rather than DNA), and has the potential to transform research and global public health.
    Produced by: McGovern Institute for Brain Research at MIT
    In collaboration with: Broad Institute of MIT and Harvard.
    With special thanks to :Feng Zhang (McGovern Institute, Broad Institute), Omar Abuddayeh (McGovern Institute), Jonathan Gootenberg (McGovern Institute), Ian Slaymaker (Broad Institute) and Sabbi Lall (McGovern Institute).
    Animation by: Sputnik Animation
    Narration by: Julie Pryor (McGovern Institute)
    Addition footage by: Scott Sassone (Broad Institute) and Sabeti Lab (Broad Institute, Harvard University)
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ความคิดเห็น • 42

  • @anthonyrcontreras
    @anthonyrcontreras 4 ปีที่แล้ว +20

    This is an easier-to-understand video explanation of how CRISPR works. Significant implications for the future of the mental health and learning difference fields. Great work!

  • @mallorymyers7525
    @mallorymyers7525 4 ปีที่แล้ว +7

    Thank you for such high-quality science communication. Well done.

  • @nhungluong5133
    @nhungluong5133 5 ปีที่แล้ว +1

    Thank you! I admire your work.

  • @endanglwidiastuti8628
    @endanglwidiastuti8628 3 ปีที่แล้ว

    Thanks so much

  • @winproduction7585
    @winproduction7585 2 ปีที่แล้ว

    Thank you 🙏

  • @userou-ig1ze
    @userou-ig1ze 5 ปีที่แล้ว +5

    why hasn't this been hyped by media yet?

    • @jeffwads
      @jeffwads 4 ปีที่แล้ว +1

      The average viewer is stupid. You should know that by now.

    • @aentropy
      @aentropy 3 ปีที่แล้ว +3

      You should be convinced that scientific breakthroughs are not something the public is fond of. Otherwise, we would be a world prospering from enthusiasm of scientific principles.

  • @sukumarsubramani2065
    @sukumarsubramani2065 3 ปีที่แล้ว +2

    How to correct genome sequencing to block gentically inherited diseas in human

  • @andriusbudrikas
    @andriusbudrikas 2 ปีที่แล้ว +1

    Where I can get it? I want to try for my autoimmune disease .
    Hope that could help :/

  • @kalrefaie91
    @kalrefaie91 5 ปีที่แล้ว +1

    Would you give permission to use some scenes from this video to be produced into another video? Credits will be mentioned of course.

  • @beatsandvibez780
    @beatsandvibez780 3 ปีที่แล้ว +1

    How can i get this done i am from fiji

  • @zooversee
    @zooversee ปีที่แล้ว

    Thank you so much

  • @ShubhamKumar-fh5hd
    @ShubhamKumar-fh5hd 2 ปีที่แล้ว +1

    CRISPR Is The Future

  • @bendrover
    @bendrover 2 ปีที่แล้ว +1

    Someone must have alot of new data after covid.

  • @hansveen7132
    @hansveen7132 3 ปีที่แล้ว

    So crispr can be used to alter the mrna instructions from outside the body?

    • @imaginationplayground
      @imaginationplayground ปีที่แล้ว

      More like it can detect and once detected it can also cut to remove functionality.
      There are many use cases based on this ability including inserting or deleting genes from DNA, lowering expression, cleavage cascade etc

    • @hansveen7132
      @hansveen7132 ปีที่แล้ว

      @@imaginationplayground So its a great cure for too many of us

  • @rahulpaul2976
    @rahulpaul2976 3 ปีที่แล้ว

    Is it possible to change skin color by using crispr cas9 tecnology??

    • @Mark-Wilson
      @Mark-Wilson 3 ปีที่แล้ว

      bro why does tha tmatter

    • @juz882010
      @juz882010 ปีที่แล้ว

      100% RNA can do what ever the DNA tells it to or is capable of as a human

  • @muynguon948
    @muynguon948 3 ปีที่แล้ว +1

    Will this help us with the COVID-19 infection?

    • @Mark-Wilson
      @Mark-Wilson 3 ปีที่แล้ว +3

      we don't need this we only need a normla vaccine bro but it might help with hiv and other rna viruses and also help us defeat cancer by fixing proto onco genes along with toher treatments! for the rpactical purpose other than medical ti could help inre search and technolgoy and help ourselves in other ways as well but the technology is stil learly its being devleloped everyday

    • @natchu96
      @natchu96 3 ปีที่แล้ว

      @@Mark-Wilson I mean...this is for detecting whether you have a certain virus in you without having to resort to draining some of your blood and shipping it to a lab to spend days testing it. Actually curing you in the event that you really are infected is not the concern of this technology.
      It's basically a pregnancy test stick but instead of telling you if you should be expecting babies, you'll know if you have COVID-19 within about an hour. Instead of maybe a week. For diseases that can spread through a community rapidly it is rather invaluable to quickly know whether it's actually there before it gets to more people.

    • @juz882010
      @juz882010 ปีที่แล้ว

      its why they released it, they never really done any RNA based vaccines, they worked terribly for the cancers they tried, the only real solution was a cold like virus to introduce RNA technology into the world. China is now gene sequencing with this technology. Having a vaccine tested on billions of people from all over the world gave them the best data they could of ever wished for.

  • @RoJD
    @RoJD ปีที่แล้ว

    😊

  • @d1agram4
    @d1agram4 3 ปีที่แล้ว +1

    I wonder whats hidden in the unnatural world around us.

  • @blauwiese35
    @blauwiese35 2 ปีที่แล้ว

  • @klam77
    @klam77 4 ปีที่แล้ว +1

    what does SHERLOCK stand for?

    • @wemster5249
      @wemster5249 4 ปีที่แล้ว +8

      Specific High-sensitivity Enzymatic Reporter Unlocking.

    • @ivaerz4977
      @ivaerz4977 3 ปีที่แล้ว +1

      @@wemster5249 damn

  • @alfaphone3675
    @alfaphone3675 2 ปีที่แล้ว

    Я говорила что там в озере говно берут вот Интел и шакед