What an amazing vision! This is an excellent initiative by this remarkable group and truly essential work. It's time we write our own stories, rather than inherit them. This company deserves all the support it can get to accelerate its efforts. I wonder why such people aren't at the forefront in our country!
I hope more governments and universities lead the way with these scientists. We don't want private companies who are for profit, using this to hold patients hostage for an ungodly amount of $$$. This means we need pro-science leaders who will put tax dollars toward funding these projects
Go science! Educate yourselves people every day so that you may have SOME IDEA what the future will bring. So that you may react to the light of discovery in a RATIONAL and ENTHUSIASTIC way And not FEAR (that stems from ignorance)
Currently, there is no definitive way to change one's APOE4 status. However, researchers are exploring: 1. Gene editing (CRISPR) 2. APOE4-targeting therapies 3. Lifestyle modifications (exercise, diet, stress management) 4. Pharmacological interventions 5. Gene therapy These methods are still experimental or in early clinical trials.
ApoE4 does not increase AD risk by itself... It requires a dietary component, hence why some African populations with incredibly high ApoE4 do not have increased AD risk. This is the downside of this technology. All sorts of people think they can be "cured", when all they really require is personalized and more importantly, better nutrition. What you want to do is a ketogenic diet. You will be just fine. Also look up type 3 diabetes.
This is way, way, way above my competence, but here goes with a couple issues/questions: (1) He posits that to solve cardiovascular issues you have to lower LDL cholesterol, and that's the key. Not so fast, my friend - there is serious doubt that there is ANY correlation whatsoever between high cholesterol and cardiovascular risk - in fact, it's been show in a large study of older Italian men (done, I think, at the University of Bologna) that the higher their cholesterol, the lower their overall mortality. A similar study showed the same in a large population of female nurses. And so on (there's more). Besides, if high cholesterol is the key, lowering can occur with statins, so why would CRSPR be such a big deal? (2) Where is the place of lifestyle in this equation? If my doc edits my genes can I still eat junk food? This seems like just another version of Big Pharma's Big Pill approach to "health care."
No matter what mankind does to escape death....God said "the wages of sin is death" death is how God pays us for our sin. If you want to live forever...REPENT AND BELIEVE Romans 10:9-11.
There been thousands of gods all throughout human history and yet you still believe that yours somehow the correct one. Anyone who believes in god has a significant problem with their deductive reasoning skills.
The potential of this new therapy could save millions of lives.. I hope it's a matter of years and not decades. Fantastic presentation
do you think big Pharma will try to push it into the future because it threatens drugs they make billions on
What an amazing vision! This is an excellent initiative by this remarkable group and truly essential work. It's time we write our own stories, rather than inherit them. This company deserves all the support it can get to accelerate its efforts. I wonder why such people aren't at the forefront in our country!
I hope more governments and universities lead the way with these scientists. We don't want private companies who are for profit, using this to hold patients hostage for an ungodly amount of $$$. This means we need pro-science leaders who will put tax dollars toward funding these projects
Go science!
Educate yourselves people every day so that you may have SOME IDEA what the future will bring.
So that you may react to the light of discovery in a RATIONAL and ENTHUSIASTIC way
And not FEAR (that stems from ignorance)
There is no money in a cure. The biggest challenge for gene editing companies will be funding.
fascinating!
Maybe by 2050 we'll see some of this technology in effect
hopefully. I’ll be 52.
@@Seven35888 😏
For nonaka moyapthi muscle fibres regeneration gene therapy when it available sir
Can this help with mental issues too like anxiety, depression or schizophrenia?
Time to read Aldous Huxley's book BRAVE NEW WORLD first published in 1932!!!!
Lets hope the greed of this country doesn't get in the way of this happening
It will
When will this therapy available for achromatopsia?
When the time comes for this, to speed up the moment, you can support and spread the idea of genetic modification to other people!
Anyone know if changing the ApoE4 status soon might be possible? I have E4/E4 …
Currently, there is no definitive way to change one's APOE4 status. However, researchers are exploring:
1. Gene editing (CRISPR)
2. APOE4-targeting therapies
3. Lifestyle modifications (exercise, diet, stress management)
4. Pharmacological interventions
5. Gene therapy
These methods are still experimental or in early clinical trials.
@@curioSphere101 thanks!
Hope there will be mitigating strategies soon… 36 years old atm. Maby thats enough time for science to find some solutions 🙌🏻
ApoE4 does not increase AD risk by itself... It requires a dietary component, hence why some African populations with incredibly high ApoE4 do not have increased AD risk.
This is the downside of this technology.
All sorts of people think they can be "cured", when all they really require is personalized and more importantly, better nutrition.
What you want to do is a ketogenic diet. You will be just fine.
Also look up type 3 diabetes.
This is way, way, way above my competence, but here goes with a couple issues/questions: (1) He posits that to solve cardiovascular issues you have to lower LDL cholesterol, and that's the key. Not so fast, my friend - there is serious doubt that there is ANY correlation whatsoever between high cholesterol and cardiovascular risk - in fact, it's been show in a large study of older Italian men (done, I think, at the University of Bologna) that the higher their cholesterol, the lower their overall mortality. A similar study showed the same in a large population of female nurses. And so on (there's more). Besides, if high cholesterol is the key, lowering can occur with statins, so why would CRSPR be such a big deal? (2) Where is the place of lifestyle in this equation? If my doc edits my genes can I still eat junk food? This seems like just another version of Big Pharma's Big Pill approach to "health care."
He is talking against pharmaceutical industry
hope it can help me live for 2000 years
It'll help you live as long as a proton ;)
I won't complain if I live to be 80 years old without any pain or disability
2000 years whats the point ?
Ahhh been over 10 years since cas 9 and I don't see no breakthrough in Medicine , step on the gas researchers ,wt r u doing
No matter what mankind does to escape death....God said "the wages of sin is death" death is how God pays us for our sin. If you want to live forever...REPENT AND BELIEVE Romans 10:9-11.
sigh 🙄
“Aragorn I am your father.” -Dumbledore 1995
Seems like people are way to optimistic rather than use a few critical thinking skills.
Thanks ‘Karen’, really living up to your name.
There been thousands of gods all throughout human history and yet you still believe that yours somehow the correct one. Anyone who believes in god has a significant problem with their deductive reasoning skills.