Glucose and Glycogen Glucose is a 6-carbon molecule used to make energy in the form of ATP Excess glucose is stored in skeletal muscle cells and liver cells as glycogen Glycogen is a large, branched molecule made up of glucose molecules linked by glycosidic bonds Glycogen Synthesis Four main steps in glycogen synthesis: Attaching UDP molecule to glucose Attaching glucose part of UDP-glucose to glycogen primer Adding more glucose molecules to the primer Adding branches to the glycogen molecule Enzymes involved: phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, and glycogenin Glycogen Breakdown Glycogen breakdown occurs in response to low blood glucose levels Enzymes involved: glycogen phosphorylase, debranching enzyme, and phosphoglucomutase Breakdown occurs in liver and skeletal muscle cells, with different enzymes used in each tissue Regulation of Glycogen Metabolism Two pancreatic hormones regulate glycogen metabolism: insulin and glucagon Insulin promotes glycogen synthesis and inhibits glycogen breakdown Glucagon promotes glycogen breakdown and inhibits glycogen synthesis Regulation occurs through phosphorylation and dephosphorylation of enzymes involved in glycogen synthesis and breakdown
Thank you Osmosis. you are my saviour. Currently reviewing for the Physician Licensure Examination . I can easily understand because of your animation. BIG THANK YOU.
I really do appreciate the effort you put into these videos ❤ But I think the rhythm is very consistent that I keep losing focus and replaying the video, almost as if the narrator's reading and not explaining. Everything else is absolutely great ❤
اگولك خالي شو بالبداية گلت الابنيفرين ينفرز من الغدة الكظرية يزيد ضربات القلب وبعدها گلت يسوي مثل شغل glocago الي ينفرز من البنكرياس في تحطيم كلايكوجين الكبد شسالفه
Nice presentation, I have question about the degradation of glycogen using phosphoric acid. could you please explain if phosphoric acid can degrade glycogen.
Hi Dilsha! We have a video on this topic that you may watch over at osmosis.org anytime! You may signup for the 7-day free trial (no credit card needed) to access our video library 😊
Guessing not because insulin also activates enzymes to do glycogenesis, (creation of glycogen, as this video shows) which causes the conc. Of glucose in the blood to decrease, serving it's purpose.
Wow, you summarized every and each detail just in 10 minutes. I really liked the animations and how to the point this video is.
Thank you! Glad you liked it! 🙏🏽
I have a question
Glycogen is present in all except:
Blood
Brain
Tissue
Heart
@@Xxwwks l think it's except the brain
1 hour before the exam
Been there before dude 😭
@@Phantom_Kraken😂😂
Same 😭
No one cares😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒
33 minutes🔥
This helped me so much!!!! I was worried about this topic on my biochem test tomorrow, but I understand so much better now.
Hi Monica,
We're truly glad we can be of help! Let us know if you need anything else, feel free to reach out to support@osmosis.org :)
Straight simple and comprehensive i appreciate your work the animation makes me understand much easier than just words
Glucose and Glycogen
Glucose is a 6-carbon molecule used to make energy in the form of ATP
Excess glucose is stored in skeletal muscle cells and liver cells as glycogen
Glycogen is a large, branched molecule made up of glucose molecules linked by glycosidic bonds
Glycogen Synthesis
Four main steps in glycogen synthesis:
Attaching UDP molecule to glucose
Attaching glucose part of UDP-glucose to glycogen primer
Adding more glucose molecules to the primer
Adding branches to the glycogen molecule
Enzymes involved: phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, and glycogenin
Glycogen Breakdown
Glycogen breakdown occurs in response to low blood glucose levels
Enzymes involved: glycogen phosphorylase, debranching enzyme, and phosphoglucomutase
Breakdown occurs in liver and skeletal muscle cells, with different enzymes used in each tissue
Regulation of Glycogen Metabolism
Two pancreatic hormones regulate glycogen metabolism: insulin and glucagon
Insulin promotes glycogen synthesis and inhibits glycogen breakdown
Glucagon promotes glycogen breakdown and inhibits glycogen synthesis
Regulation occurs through phosphorylation and dephosphorylation of enzymes involved in glycogen synthesis and breakdown
This is super helpful for my first exam ever in dental school!
Glad it was helpful and best of luck! 😊
Thank You Very Much! Very useful! Just watching it before 5 hours to my exam!!
I have same stituation
Same
I am in a similiar situation😂
Please keep on making more biochem videos,they are so helpful.Thankyouuuuuu😊
This was amazing. Thank you so much! This helped me reconsolidate everything I needed for the MCAT, and the animation was beautiful and concise.
As a visual learner, THANK YOU!!
Most welcome, Majo! 🙏🏼
Thank you Osmosis. you are my saviour. Currently reviewing for the Physician Licensure Examination
. I can easily understand because of your animation. BIG THANK YOU.
Most welcome and best of luck! 💫 🥰 💖
the amount of concept in just 10 minutes is just insane! great video for a quick revision of the topic.
Thanks! 🥰❤️🙏🏼
This video is a godsend, thank you so much for making it! Clear, concise, and quick. Good stuff!
Happy to help! 🙏🏼
Great video. You guys make complicated stuff go easy as always. 🤗
Glad you think so, Ahmed! 💖
2:49 the right Pyrophosphorylase cuts one phosphate from glucose-1-phosphate and the second frome UTP ☺️
thank you...it was way better than my lecturer's explanation.
Glad our video is able to help! 😊
This was so easy to understand and the animations make it fun and interesting! Thaaaaaanks
Glad you liked it, Santi! 😊
May Allah guide you and grant you Janna for spreading knowledge in a sincere way 🌸🤲
channels like this are so helpful, thank you so much!
You're very welcome! 💕
Thankuuuuu soooooo muchhhh. Pls make more such vds on biochem. Like protein structure, folding
This guy is a genius at simplifying complicated stuff
Glad you think so, Joseph! 🧠 🤓🫀
Sir animation plus your teaching style of easy explaining is awesome
Brilliant explanation through beautiful animation 🙏
Best video on this topic i have come across.
Wow, thanks, Poushalee! 💙
the enzymes are so cute. Thanks for putting in the effort to make the video entertaining. Helps with getting through the content.
Glad you enjoyed! 🥰❤️🙏🏼
i cannot believe you explained all that in 9 minutes. i took my teacher 4-5 hours and I still didn't get it
Glad to help, Vatsala! 🙏🏼
Thank you Osmosis 💗
Any time! ❤️
Thank you so much my all doubt is clear in this video very nice video 🤗
Happy to help 🙏🏼
5 minutes before exam at 2x speed
😂😂😂😂😂
I feel you bruh 🤧
Thorough explanation with complete understanding , thanks so much...🙌🙌🙌
Thanks for the feedback, Mike! Glad you liked it! 🤓
Beyond amazing! What an apt explanation!
Glad you liked it! 😊
a summary of a 2 hours lecture in just 10 minutes WOW
We hope this helped, Ibrahim! 🙏🏼
Does glycogen metabolism include both glycogenesis and glycogenolysis?
I hope that you read my commentary
I´m studen of nutrition here in Mexico and your videos helps me to practice my english and to review the topics :'D
That's great! Thanks for letting us know, Marcos! 🥰❤️🙏🏼
Sir Your Teaching and Explaning Method is fantastic 😍 Thank you very much Sir
You are most welcome! 🙌🏼
to the point 👌
thank you osmosis ❤❤
Most welcome! 😊
I really do appreciate the effort you put into these videos ❤
But I think the rhythm is very consistent that I keep losing focus and replaying the video, almost as if the narrator's reading and not explaining.
Everything else is absolutely great ❤
Thanks for the feedback, Sara! 💕
I wasted 4 whole ass hours trying to understand it from that damn book 😭 should've watched this instead
Amazing description 👏
Thanks, Ansa! 🥰
Thanku so much for making this video , it helped me to understand this topic clearly.
Glad to hear that! 😊
Thank you sir
Very nice presentation 👏👏👏
Thank you❤️ was really helpful!
This was so helpful! It helped me understand everything, thank you so much!!!
Glad to help, Raquel! 🥰
Good explanation. Cheers.
You're welcome! ❤️
Thank you!❤
You're welcome! 😊
this was awesome! thank you!!
Our pleasure, Leif! 😊
This video very helpful , Thank you.
Just wow . It was all clear to me . Thanks for such an amazing video
Always our pleasure to help, Debashish! 🙏🏼
I really appreciate this perfect work, I understand this now
Thanks for appreciating this, Owen! 💕
From Iraq thanks ♥️♥️♥️
I swear the voice is the same guy who runs Science Simplified
Very simple and great job! 🔥
Thanks, Maysam! 🙏🏻
Wow this effort is just impressive ! Thank you so much
Glad you like it, Bayan! 💕
Im having trouble understanding what you mean at 2:38. "Which uniquely comes in the form of uridine triphosphate". Im so confused here
Hi there, thank you for your feedback. Please do send us an email so we can connect you with our content team. support@osmosis.org :)
Excellent depiction
Thanks, Haseeb! 😊
That was very helpful I understood so well, good job sir :)
Thank you!!
You're welcome, Laboni! 😊
Good explanation....would like to fund you in future after I get a job😅
Thank you❤
You're welcome, Hassan! 😊
beautiful explanation
Glad you think so, Ayeni! 💙
Still none the wiser to following this. Such a long , complicated, process.
Just watch it over and over again until you learn it subliminally 🤷🏿♀️
اگولك خالي شو بالبداية گلت الابنيفرين ينفرز من الغدة الكظرية يزيد ضربات القلب وبعدها گلت يسوي مثل شغل glocago الي ينفرز من البنكرياس في تحطيم كلايكوجين الكبد شسالفه
الابنفرين عنده اكثر من وظيفة يزيد دقات القلب وكذلك يساعد بتحطيم ال glycogen الي مخزون بالعضلات وعنده بعد وظائف اخرى
Thank you💞
Great video
Thanks you ❤
Thank you too! 😊
Thank you ♥️its very helpful
1:19 only GLUT4 is insulin dependent ?
very helpful...thanku so much
On point video ❤❤❤❤❤❤
Thanks! ! 💫 🥰 💖
Half an hour before quiz😂
Great explanation thank you so much
Our pleasure, Tipime! 💖
thank u💚
where the glycogen is save on cell?in endopelasmic reticulum?
Thank you for presentation..
Nice presentation, I have question about the degradation of glycogen using phosphoric acid. could you please explain if phosphoric acid can degrade glycogen.
Thank you very very very much
Wow amazing thank you so much🙏
You’re welcome! 😊
awesome,,,
just wonderfully awesome
Thank you, Bilqis! Cheers! ❤️
Great info thx 🙏
Superbb explanation tysm
Most welcome, Neha! 😊
thank you
U r just amazing!😮
Thanks, Supraja! 😊
liver cells have glycogen.. in what form those glycogens are stored, as fat or glucose ??
Thank you very much. Super.💝
Welcome, Réjeanne! 😊
I didn't understand why the udp while the glucose can make abond directly
Awesome broh
Where does step 2 begin? That's the only part i don't understand :(
I love it!
Please add a vdo of cholesterol metabolism plsss
Hi Dilsha! We have a video on this topic that you may watch over at osmosis.org anytime! You may signup for the 7-day free trial (no credit card needed) to access our video library 😊
Hi! Can you please make a video about Carbohydrate Metabolism? I would appreciate it very much! Thank you.
Hi April! Thanks for leaving your comment here. Please do instead send us an email at support@osmosis.org so we can check your request. Thanks!
Since diabetics have less intracellular insulin, do they have more glycogen?
Guessing not because insulin also activates enzymes to do glycogenesis, (creation of glycogen, as this video shows) which causes the conc. Of glucose in the blood to decrease, serving it's purpose.
thank u very much
IM LITERALLY GONNA DIE THANK YOU SO MUCH
Thankyouu so much!!
Most welcome! 😊
Thanks a ton....
Most welcome! 🥰
How u made it soo easy good job
Thank you, Maram! 😊
2 minutes before exam on 6x speed
We hope this helped! 🥰
I'm a software developer what the funk am I even doing here. Love it though
I'm sorry
Biochemistry is a general course added to my course of study
Very important yes
But this all sounds like Spanish
I'm so clueless
Great🥳🥳
Thanks, Dilsha! 🥰
Great!
Thanks, Alaka! ❤️