How Do ACE Inhibitors Work i.e. Ramipril (Nursing Pharmacology)
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- เผยแพร่เมื่อ 19 มิ.ย. 2024
- How Do ACE Inhibitors (Ramipril) Work? (Nursing Pharmacology)
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Antihypertensives are a common group of medications used to treat high blood pressure (hypertension). Nursing students, nurses, and all healthcare professionals working with patients need to know how this drug works in the body and be aware of the potential for serious side effects.
ACE inhibitors are angiotensin-converting enzyme inhibitors. This means they prevent angiotensin 1 from converting into angiotensin 2 - a potent vasodilator. This will help to reduce blood pressure. In this video we cover the following topics:
Time Stamps
00:00 Introduction
02:17 Five Main Drug Classification to treat Hypertension
02:58 Outline for Video components
03:18 Renin Angiotensin Aldosterone Pathway Review
06:01 Generic Names, medications ending in “pril”
06:43 Administration
08:18 Side Effects
11:52 Considerations: Liver and Kidney Disease
13:25 NCLEX Review
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You are the best Pharm teacher I have come across! Please come to Nevada and take over our Pharm department! We need it.
I am learning SOOOO MUCH from your videos, .... Far MORE than ever explained from my own Cardiologist .... My sincere "Thanks" !!!!!
Ah’. That’s so great to hear.
Thank you this is so valuable for someone who is newly prescribed ACE inhibitors. I love understanding why i might get side effects and what i might need to tell my doctor .. thank you x
Awesome!
You are excellent at explaining!! The visuals, the reiterating, wowow thank you thank you
Thank you so much. I’ve recently started meds and this is so helpful. Really enjoyed your explanation. 🏴
Thank you
I can’t wait to watch all and note them. Thank you !!! What an awesome teacher
Hi, the N95 mask that you need is the one that fits your face. If you are in healthcare, or front line service like police and fire, you will be tested to make sure there are no leaks. If you are in the community buying them off the shelf, there is no way to know if there are leaks (trust me - I have failed many a mask that were snug on my face)
Very good! Explains why while I am relaxing and on blood pressure medications, I feel lightheaded, dizzy a bit, and almost a sense of nausea, I begin to feel my blood pressure rise for no reason at all, my heart rate pulse is elevated. After a few hours, I begin to sense a calming change in my body to where I feel more normal again! May not be quit exact to what you are saying, but I feel more relieved by your explanation! Thanks! I see my doctor tomorrow also to explain my events.
Awesome! Give thanx ❤
Thank you
Great teacher great video thank you for the info
Great videos! Very helpful for reviewing and better understanding pharmacology for this RN!
Thanks! So happy they help
Awesome explanation, makes ACE inhibitors understandable👍🏼👍🏼
Another great video. Thank you for helping us, Tammy
Thanks Toni 🤩
I’ve recently been prescribed ramopril so this has been a useful video.
Awesome!
Thank you for this. I’m a new follower.
Thanks for supporting
Thank you so much for covering the science behind the medication! I feel like this is crucial knowledge in order for me to answer NCLEX questions accurately rather than just memorizing side effects :)
Glad it it helpful! Thanks for letting me know 😊
Your videos are so helpful, thank you!! Is angiotension a protein hormone??
Nice explanation.
You are awesome!!!
You are a God sent 💕😍😍thank you
The N95 mask in the healthcare field is fit tested - so we have a wide range of them, and if they are not tested to determine if particles are leaking in - then we don't use them. The general public does not have access to the testing so it is a gamble. Even when you think those masks are tight - they can still leak, which is why we have to be tested on a regular basis, Lose weight, gain weight, and your mask needs to be refit.
I like the visuals... I always remember that APRIL is hypertensive. Ace + PRIL= APRIL 👩🏼🔬
Great addition!
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I was dumb forgot my account password. I love any assistance you can give me
@Juelz Baylor instablaster =)
nice video very helpful for my examination
Awesome :)
Very very informative
Thank you for writing 🙂
Hi, really love the video and I learned a lot. I have recently been diagnosed with Nonischemic Cardiomyopathy (sorry if that is not spelled correctly) and have been prescribed both Ramipril and Bisoprolol for it. But I dont have high blood pressure and my heart rate rests at 70 bpm. So I have been told these meds with ease strain on my heart to stabilize it? Are there any videos are thoughts you might have on these medications being used for my predicament? Sadly they have been making me want to dry heave a lot so my GP has me only using the Ramipril right now to see which one is causing to feel that way. Anywho, thanks for these videos. Appreciate you!
I am happy to hear you are working with your healthcare team on this. They will be in the best position to support you
Hi just listened again. I am on Ramipril 5mg and have the dry tickly cough. Should I change medication or is there any treatment for the cough? Thank you so much.
This is a great question for your healthcare team. They will have a more complete picture of your health.
Great friend ❣️
Thank you 🤗
Hi! First of all, thank you so much for this video! Second, if one is taking Ramipril and having lethargy, cold sweats, malaise, and because of Covid medical attention is sparse (more still on the weekend) -- are there some foods / supplements that would help someone transition onto Ramipril without a few days of feeling really down?!? Thanks.
Hi! Those sound like good reasons to connect with your healthcare team - I am not in a position to give medical advice. The signs may / may not be related to your medication
Great vid
Thank you
Thank you that was well explained. I have enlarged vessels on my feet and hands and some lower leg swelling also recently chilblains and some ankle ache. My heart rate has slowed. I have been taking Ramipril 5mg for about 6 weeks. Can you advise how much the medication may be the cause. Just general without obligation. Thank you very much.
With the heart rate slowing, it may be contributing to the engorgement of the lower limb vessels, and a great conversation to have with your healthcare team. Often we have a multi-prong approach and you may need to add salt restrictions if you have not already. I have a video on heart disease
@@NurseMinder Thank you very much. The swelling started when taking Amlodopine and has not really subsided since changing to Ramipril. Health care team are elusive to contact so other help much appreciated.
Love the presentation. Q: When talking about ACE inhibitors, are we talking about the drug inhibiting ACE-2 Receptors at the molecular level ? The same receptors that interact with mRNA vaccines to create a spike protein ?
I have not heard about a connection to mRNA vaccines. Do you have a resource I can review?
@@NurseMinder I'm sorry. My question must sound confusing. I'll try to explain this with more precision. Your video was discussing how ACE Inhibitors work. My follow-up question is multi-fold. 1. Are these ACE Inhibitors inhibiting ACE Receptors at the cellular level ? AND IF SO
2. Are these receptors inclusive of the (ACE-2 Receptors) that we hear about when an antigen is introduced to create spike proteins ? 3. IF answer is YES; then wouldn't taking an ACE Inhibitor be counter-productive when being vaccinated with mRNA based vaccines where the Ace Inhibitor would cancel-out the creation of the spike protein ?
Will sometime get used to taking Ramipril in terms of side effects? 5mg od, how long would it take to not feel weird?
That is a good question. As everyone will adjust in different ways. Connect with your healthcare team as they are the best people to guide your care
Well explained, thanks! Ramipril can increase heart rate to balance, so if someone takes nebivolol (a beta-blocker) to decrease the heart rate, will it be dangerous? What does a blood pressure of 130/70 indicate? Higher systolic and lower diastolic. Let's say someone is using 250 mg of testosterone per week and his BMI is 33, he is by default hypertensive, mostly because of the excess weight. High amounts of testosterone in the body also increased sodium retention and aldosterone. So the person takes eplerenone 25 mg in the morning, 2.5 mg nebivolol BID, and Ramipril 2.5 mg at night to counter the issue. He wants to use testosterone because he needs the extra energy and cognitive benefits to cope with his new stressful job. What would be a good move to make the situation less complicated and safer without compromising the testosterone therapy?
Sounds like a great question for your healthcare team! There is a lot to consider in this post and I am not in a position to comment
@@NurseMinder okay, just tell if nebivolol and ramipril combo is safe or not (in general).
Combo therapy is often an effective strategy
Immediately after you write that angiotensin2 vascodilates, you offer that blood pressure is positively lessened by suppressing it. Perhaps a wedge in-between indicating the hearts importance in management of blood pressure might not apppear to contradict?
Also, the hormone induced by the adrenals to dehydrate while pushing 'potassium' - how much of that depends on 'salt'? 'Calcium' is less volatile, produced in histamine reactions to also vascodilate. The accumulative potential of all three, which requires correction to avoid 'hyper', does not appear to be factored in simply by blocking betas. How will favouring the positivity of heavy metal also redistribute it systemically? How to avoid the need for organ specific environmental detox, which adds more stress than continuous flow.
great points - sorry I am just seeing this now - I often look at comments on my phone and logged online today to see I have missed hundreds of comments? so weird
I read on media what food not to take and i cant take nuts, green vegies , red grapes...all the healthy food interact with this meds😢
Better to be informed and talk to your pharmacist
I took remapril, with ckd. My gfr went down 4%. Not recommended for patient with poor kidneys. I was switched to amoledipine, got edema , even calfs were sore. Many contraindications with medicine. Even diaretics can have problems.
Yes there is a lot to consider and that is why I recommend people talk to their healthcare team :). I have had many a patient not disclose things to their team. Medicine is not a perfect science- so teamwork is important
So i have to minimise food that has potassium?
You will want to monitor it - best to talk with your pharmacist
💖
OD means right eye. Shouldn't it be QD???
Where in the video did you notice this - I will watch and answer
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Haha. Stop watching the news is so legit! Get out there and live :)