Drug Addiction: How Opioids Like Fentanyl Work
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- เผยแพร่เมื่อ 27 ม.ค. 2022
- This video has been updated to include information about Fentanyl. View the updated video here: ttps:// • Opioid Addiction and O...
#opioids #OpioidAddiction #fentanyl
MEDICAL ANIMATION TRANSCRIPT: Opioids are drugs that are prescribed to treat moderately severe or severe pain. Examples of these drugs include hydrocodone, oxycodone, morphine, hydromorphone, and methadone. Heroin, an illegal drug, is also an opioid. In order to understand how opioids work, it’s important to know how your body feels pain. The process begins when something harmful happens to your body. Information about this harm is converted to a nerve signal. The signal passes along nerves to your spinal cord and brain. In your brain, the signal is perceived as pain. Opioid drugs affect how you feel pain. They attach to structures, called opioid receptors. These receptors are found on cells in your brain, spinal cord, and other areas of your body. Opioids act on these receptors to make you feel less pain. These drugs also have different effects in other areas. For example, opioids act on the reward pathway in your brain. This causes a release of a chemical called dopamine that results in a happy feeling, or “high.” Opioids may also cause slower breathing. And, they may cause reduced motion of your intestines, resulting in constipation. For most people, when opioids are taken as prescribed for a short time, they are fairly safe and effective. But, these drugs can be taken in ways that weren’t prescribed, such as taking too many, taking them to get high, or giving them to someone else. Misusing these drugs can raise your risk of developing drug tolerance, dependence, addiction, and overdose. Tolerance means the drug is less effective over time. This can happen when opioid receptors become less sensitive to the effects of the drug. As a result, more of the drug needs to be taken for you to get pain relief. Dependence happens if a person has symptoms when they stop using the drug. When the drug is removed, or withdrawn, you feel sick. This sickness is called withdrawal. Opioid withdrawal has flu-like symptoms that include restlessness and anxiety, muscle aches, inability to sleep, watery eyes and runny nose, nausea and vomiting, stomach cramps and diarrhea, and dilated, or widened, pupils. Opioid addiction is a brain disease where you have an overwhelming craving for the drug. You can’t stop taking the drug despite the harm it may cause you. Addiction is not the same as dependence. You can be tolerant of a drug or dependent on a drug, without being addicted to it. Finally, opioid overdose is a condition where taking too much of the drug can cause life-threatening symptoms, or even death. The symptoms of opioid overdose can include confusion, feeling very sleepy or not alert, nausea and vomiting, constricted, or small, pupils, unconsciousness, slow or stopped breathing, and death. According to the Centers for Disease Control, over one hundred Americans die each day from opioid overdoses. If you have questions about opioids, or if you or someone close to you needs help for an opioid use disorder, talk to your healthcare provider.
ANH21245
I used to be addicted to hydrocodone. It was never prescribed to me. The withdrawals were sooooo bad…. I can’t explain how bad. It’s like I had to get through not sleeping for a week and a half, with the most restless feeling, and body aches, just to start to get a leg up on quitting them. I actually couldn’t do it. I started taking meth, and that made it a lot easier, and that was a lot easier to quit. No lie. Been clean and sober now for almost 7 years.
luke luke me also almost 7 years never ever wanna feel that way again i am 1 pill away from being addicted just like cigs 1 puff away from being addicted 8 years in august on that CONGRATS
Good job bro 👌
Another meth success story
Good luck buddy
@@trtrhr meth is to Adderall/amphetamine what crack is to cocaine.
I used to be addicted to fentanyl. I took what i was a Percocet and found out later that it was laced with fentanyl but at that point, it was too late i was already addicted. Literally the worst feeling i’ve ever felt in my life. The withdrawals are unimaginable i literally had every type of symptom at one point I wanted to end all of it but i stayed strong and pushed through. this was only 1 month ago. I never wanna go back to that and hope to god no one ever has to go through what i went.
How do you kno your on fetanyl?
still addicted to fentanyI and oxy, i go buy laced percs on purpose
@@nex6260 ok?
@@nex6260 hope you get better soon my g. I know it's hard but you can do it
We are victims of cartels!
I hope you will do a video on how pain hijacks the brain. My best friend killed himself because of chronic pain from a terrible accident. He was the toughest guy I knew but the constant agony overwhelmed his life. I wish somebody had understood that pain kills too.
im sorry for him :( physical pain is the worst
@@simosimosimoock5809
Thank you.
@@nisanight2247 Thank you for this comment. I have severe chronic pain and the pain and the constant thoughts of just ending it are consuming my life. But I have 2 school aged kids, and I can't put that trauma on them, or my husband.. at least for now. Every second of every day is pure torture, I really don't know how much I can take it anymore.
Pain absolutely kills, day by day, or until we can't take it anymore.
I'm so sorry about your best friend. Believe me, if he could have held on any longer to protect the people he loved from the hurt and pain, he would have! The never ending pain becomes all consuming, and it's literally all you can think about, all you want to do is make it stop... I'm sure that you've been angry with him at some point and thought that you could have helped him, but you couldn't. I really hope that if you haven't already, you can forgive him... I wish you peace 💜
It’s a shame doctors do not want to prescribe opioids to people that have legitimate pain issues due to addiction potential. What they don’t seem to care about or understand is that there is no other solution. I would much rather live with addiction then live with chronic pain. They’re pretty much telling patients “oh well deal with it” simply because they think addictions more harmful, it’s stupidity.
@@girlonfire8855 what injury or condition do you have. I feel so sorry and pray you find your peace. Does medication help you ? Prayers to the all mighty 🙏
Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.
Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
YES very sure of bergwilly11__. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I wish they were readily available in my place.
Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac.
He's constantly talking about killing someone.
He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.
@@JamesTaylor-ff4dpIs he on instegram?
Microdosing helped me get out of the pit of my worst depressive episode, a three year long episode, enough to start working on my mental health.
Wow reading some of the comments and how some of you are struggling , my heart goes to you and your in my thoughts in prayers. Sending you good vibes to fight the battle of addiction, you can do this
I have been on an opioid for the past 3 years due to chronic osteoarthritis. Without it, the chronic pain would lower my quality of life until I wouldn't even want to get out of bed each day. My pain doctor trusts me because I don't abuse it. I use it before bed so I can sleep without that nagging pain. Just a few weeks ago, a good friend from my high school days killed himself because of chronic pain. I understand the need to regulate prescriptions but there are many of us who need the medication to maintain our quality of life.
I’ve been on my meds since I was 21 I just turned 34 I have fibromyalgia and lupus as well as scoliosis the first few nights the pills made me feel super weird but comfortable enough to finally get some sleep these days I just take them to keep my symptoms to a minimum but will still have days where I can’t sleep for 5-10 days sometimes
I say the same thing all the time. Chronic pain kills. And when doctors look at you like you're just an addict and try to give you the whole "try physical therapy again" or "here's some Neurontin/Gabapentin, try that instead of opioids and let me know how it works out", you have to follow their orders, and meanwhile you're dumping money on something that isn't working for you AND you are suffering the entire time. Then you have to pay more money to go back and see the doc again to ask them for help, and they just go "well you're too young to be on opioids" (I got that a lot after I got out of the army, as if you don't feel pain as strongly because of your age or something). Even when I would take my shirt off and show them my three surgical scars, "physical therapy and ibuprofen" were usually their responses.
basically they'd tell me to kick rocks.
Thankfully I have found a pain management doctor who takes my pain needs seriously. She saw how my life was deteriorating and put me on an incredibly low dose of methadone (pill form). I can actually sleep most nights now.
It’s a really good idea to find a doctor that takes time to learn about you and work with you. Chronic pain is awful.
Why not try CBD
This is the reason why these medications should stay legal and available.
Sober almost 10 month. Life without opioid is awesome 😊💓
Does it really get better need some positivity
@@trow3 yes it really get better.
@@trow3yes it does u just got to be strong through withdrawal
L, you’re missing out
@@a.kamileon i got sober thank you very much
as an author this helped me write about my opioid addicted character, thank you
I've been on tramadol for what has to be at least a year now. Treatment like radiation therapy and major surgery for S4 cancer left me with damaged nerves that cause a lot of pain, especially when it's time to sleep and I am a total b-word when I don't get enough sleep. These drugs can be abused, but some of us really need them just to function day by day.
How have you been doing on them? I used to be on them for nerve pain but had two seizures off them since that’s a side effect and they didn’t want to prescribe me anything else so now I just deal with the pain the best I can
Are you still using it
yeah tramadol is horrible to get off of too. and its a non narcotic. worse that hydrocodone in my opinion
I was prescribed tramadol for a year too for chronic gastritis pains, I didn't know much about drugs, all I knew was that the drugs are really making me feel good and completely takes the pain away, I didn't realize am developing drug resistance which will later on become dependency, my first experience of withdrawal symptoms I was out visiting a friend for a sleepover and left my pills, I hadn't taken them for about 24 hours, I felt so sick, runny stomach, unexplainable restlessness, abdominal pains, cramps in the stomach, feeling dizzy, I couldn't sleep till morning... First thing I did I got up in the morning and drove back to my place, I took 2 pills and 3 hours later everything was good, I was calm, I was okay as if I am normal. I got worried so I did a research on the drug, I found out that what I was going through was withdrawals and I had developed dependency on the drug, I tried on my own to stop by withdrawals would just be too much... Until I took a decision to seek for professional help, I went through therapy, I got hospitilized and went through detoxification process. I got my life back, it felt like heaven having to live your life without panicking when your box of tramadol is running empty... My psychiatrist said "Tramadol is the worst opiod ever that you can abuse" he said that though it's withdrawals are not deadly, but they definitely extremely terrible. After they took me off tramadol in hospital my withdrawals only last 24 hours, and then after the medication used to treat them started working in my body, and fortunately enough no organs in my body were damaged yet as a result of drug abuse. I am grateful and I so wish everyone with an addiction, dependency or resistance would one day get their lives back!
Taking them as prescribed can also lead to addiction. 🤦🏻♀️
Big pharama only care about profits
That's why they said "for most people"
You can be addicted to anything. Addiction is the disease, not the substance.
Clearly u missed the rest of the sentence 🤦♂️ she said as prescribed… for a short period! After a period of time your body gets used to it and yes u get addicted.
Not if you have a normal doctor
i was in a horrible car accident and no doctor would prescribe me any pain medications and i couldn’t function as a result. i lost my job and i lost my friends because i couldn’t even leave my house. i’d rather live my life dependent on pain killers than attempt suicide again because the pain was so unfathomable every second of everyday.
Thank you. This was so educational, I'm in Australia and it's becoming a huge problem over here as well. I watch another youtube channel too called 'The Life Boat' that really focuses on educating people on drugs and living happily in sobriety. Recently they have had a lot of shows about Fentanyl. They have a live stream at 5pm (Pacific Time) everyday except Wednesday and Thursday and you can call in live to talk about your experiences and ask the hosts questions. They are extremely knowledgable, helpful with no judgement and I know for a fact they have already saved quite a few lives. It's just a loving, friendly place to go, regardless of what is happening in your life and love helping people.
Your channel and other ones like this are really needed to educate people about this horrific, growing nightmare .. so many people are dying. Thank you again for your video. Please be safe everyone.
I am a chronic pain patient. Honestly, I need opiates. Nothing has worked for my arthritis. I was on the same dose of Fentanyl (patch) for 15 years, so not everyone goes up and up in doses quickly. Day to day living would be impossible without an opiate. I feel NO HIGH whatsoever. That is because it all gets used up counteracting the pain. Hope this helps a few people understand why they are still such an important treatment modality for pain patients.
@@Sweet2eatbaking Sounds familiar. I'm also in the UK and I have wondered about trying the patches you are on. After 14 years of being on the same dose my patches began to lose effect on Day 3 of use. So in the end the doc increased the dose but I still have the same problem. I also take anti-inflammatories on bad days. I wish people understood. Its an unfortunate fact of life that most pain relieving substances can be abused - but as you agree, those who really need them don't tend to experience any high.
There are some TV shows I've seen where doctors get patients off their meds by making them swim in very cold water and so on! They don't tend to cover people having heart attacks from shock on those shows though! These alternative methods aren't realistic for the majority of chronic pain patients. And actually you will find many of the "miracle" stories are misreported by media anyway. I know personally a woman who swims in the sea for her migraine, she lives in North Wales. Her migraines have decreased in number since she started, but they haven't stopped. Still, the newspapers report that her migraines totally stopped!!!!
I understand you & feel your pain. I have chronic osteoarthritis and I take an opioid with Indomethecin 75 mg ER each night so I can sleep. Nothing else has worked for me.
Same boat- never felt high on my Fentanyl patch (only felt “woozy” with high IV doses when intubated)
Baby girl where you at? I need a patch!
Short, clean and informative. Every educational video has to be like that! Great job
the founding fathers forgot the birds and the bees sex education blows my freaking mind no human has any idea about pregnancy not not even femaleshow do I know start reading watch TV see females dancing on tables for money the American dream
I was prescribed 130 5mg oxycodone tablets after a chest reconstruction surgery when I was 14. Imagine giving a 14 year old that many oxycodone. I am thankful I only ever took four.
I likewise had pectus excavatum surgery in my teens and was prescribed oxycodone- as well as valium. Thankful that I never developed an addiction despite taking many painkillers!
I'll take the rest off of you. ;)
@@dando2841 I don't understand the thought process of the doctors that prescribe children ridiculous amounts of opioids
@@dando2841
Addiction is genetic. You will either light up like a Christmas tree on opiates or you won't. It's just like alcoholism, thousands of people drink socially and never become addicted, but a few will become alcoholics due to their genetics. The vast majority of people are like you.
i was 17 when i got my motorcycle and wrecked after 3 months of having it. trying to have too much fun i broke my hip and my femur came out of place. they prescribed me 30 10mg oxycodone after my surgery. 20 of them were white and the other 10 were little pink ones. i did end up taking them all but i never had any issues or any craving for more. i never even felt high, only sleepy and relieved from pain.
It hijacked my brain for sure. Still is, it's rough because I want to quit so bad and do every year but I end up going back.
Back to the pain and withdrawal, wanting to die. Such a bad way to live.
Exercise. Run. You can do it. Go on long hikes and dont reward yourself with anything at the end. The exercise is its own reward.
Ask for help. Alot of people out there want to help you. You can do it man
I feel ya brother it’s a hella of drug
I had to quit my job, move, and get new friends. And even now when I hear painkillers I have to leave the area or I will find my way to it…
@@princeloren86 You're doing the right thing. Keep at it and find something you love more than yourself.
I will say the damage caused by constantly feeding your brain "happy" through chemical use is pretty bad..once your clean some people get to the point they no longer can feel or process "normal" emotions specially pleasure or excitement the lasting effects and damage can be scary..and most often create mental health issues like anxiety and many others,addiction is a very deep science in itself..I pray for those who are actively using.🙏
Indeed thank you for noting that for everybody really helps are youth become more aware and think twice.
This comment is perfectly said I've been trying to describe this feels you said it how I would describe what's happened to me so I pray meditate push weights yoga try to maintain a stable balanced day. Methedone hard drugs weed ciggys was also my reward system was poly user now that systems gone I engage in massage councilling reiki to release 33 years of toxins built up in the body after 3 years my body is now calming down mind is still over active had massive hypersensitivity to everything skin condition for a year was chronic residue leaving via skin layers I still get massive cravings I fight not to use embrace the feels as trauma presents without useing to covrr the trauma releasing diagnosed with ptsd recently may have been underlying factor why I was a addict 33 years. Blessed be not to be feining learning to live my best life
Take it from me....DO NOT TAKE OPIATES UNTIL YOU ARE DYING
@@tanyagerrard3053 I fully understand I used for over 8 years I've been clean for four no desire to use or go back even on my worst days but the damage caused was my chronic depression and anxiety it's sooo bad I'm like a emotionless zombie unless anger or anxiety pops up I wouldn't wish it on my worst enemy I just try to educate as many people as I can about the damage's so they can spread the word and maybe help others before it's too late..I'm glad your doing ok it's a huge deal 🙏 your a tough one keep going strong 💪
Thank you so much for making this video. Usually topics like these can make me feel stressed, uneasy, and even physically sick but I felt none of that as the video was calm and straight to the facts. This has also been very useful for me too as I have a friend who takes unprescribed opioids and I want to learn more about it so I can better understand why they take these drugs, how they make them feel, etc.
I wouldn't have understood or loved biology if you wouldn't hv existed🥺😇please please please NEVER stop uploading such beautiful content🙏❤️It's a fuel for many like me:-*
I have been on an opioid for roughly18 years for chronic nerve pain(PHN). I have never had the need to increase the dose and have no side effects. I have never felt “euphoria” However, once the most effective opioid was prescribed 6 years ago, the pain had decreased from level 7 down to nearly 0 during the day and 1 at night. I cannot begin to describe what that meant to my quality of life! I have read the research on chronic nerve pain and experimental treatments (Tried many of them). I am hopeful that the knowledge gained through research will eventually lead to a medication that turns off the chronic pain response. The first paper on that was 2011. The gene which codes for the protein that controls the chronic pain “off/on switch was found. Sadly, I have heard no more, in terms of clinical trials following that amazing study. Chronic pain patients with ‘increased plasticity” in the brain,keeping the pain messages active, should stay hopeful. Our understanding of chronic pain is slowly getting to a better, more effective, solution.
Your prolly high as a kite and don’t even know it 🥴
Don't ever think about increasing your dose because that's how you get hooked you take a little Xtra for pain and then you feel that good feeling once and it's just a terrible cycle but I use opioids for my back pain it's straight up hell but if I don't have any least one pill I will hurt so bad but if I take at least one two a day is best but I won't hurt as bad as I do and I'm able to move and spend time with family with out excruciating back pain
I also have never felt “euphoria”. My Doctor says the opiates get used up in the pain receptors.
You guys should use mary wanna.
@@anthonylaszlo7487 I've been smoking for over 5 years now bruh it does absolutely nothing after smoking that long
These videos are so well made for didactic purposes. What a great job.
Thank you very much!
I agree. The video is didactic. But being didactic is not _necessarily_ being entirely truthful. It may be, or it may not be.
Thank you for giving these precious knowledge with us 😊❤️❤️👍
Clear, concise and very informative. Thanks !
I was a heroin addict for 14 years and on methadone for 10.5 yrs, I’ve been clean from heroin since April 2021 & clean from 45ml meth, in November 2021, worst thing I’ve ever done physically, took me months to get over methadone withdrawal!
You stopped cold turkey from 45mg of methadone? Why not go down to 10mg per day (or even 5mg or 2.5mg)? That seems unnecessarily harsh to do that to yourself when you could have tapered down.
I am very proud to say that 4 days ago I had success getting of fentanyl patches I was using for pain by weaning myself off of them and now I feel like a huge ball and chain has been removed.
That’s great!How did you do it?
Well done!!!
I'm happy you're trying, but let's be real, 4 days isn't enough time to consider yourself "done". I'm really hoping you succeed, but please give yourself a margin of error and forgive yourself. Addiction is a disease, not a choice.
@@Evravon doesnt done mean done ? .. 24 hours gets the biggest cheer in the rooms .. all we got is twenty fours hours .. when you have a choice be proud .. don't cast doubt .
Well done Dave .. fantastic to hear ..
Chronic 24 hour pain is such hell. Especially after years of it. What’s worse is wanting so desperately to end it all but not being able to do that to my family especially my grandchildren 😢
I feel your pain. Battling a terminal illness with no cure or treatment. Was on over 200 mg of morphine and fentanyl patches and oxycodone and more as they were just trying to make me comfortable before I would pass away. Now over 10 1/2 years it’s so incredibly hard to stop. The withdrawals had me in cramping mode unable to move off the couch for 3 weeks. Had I known I would live this long I would have come off sooner. My quality of life still sucks as I have autoimmune disease that wrecked half my organs almost 11 years ago and the other half are failing at a painful miserable fast rate. God Bless you.
You are so right.... I've been in chronic pain for 24 years because of Crohn's disease, degenerative disc disease, osteoarthritis and a few other things because lets add on more issues n make my life more miserable.... sometimes pray I don't wake up in morning... the only thing that keeps me going is my son n opioids.. and now we have to deal with the stigma of these pills because so many people are addicted to it. ... I pray for the ones that have to take it and I pray for the ones who are trying to beat their addiction..
@@leegreen316 as if life in 2022 wasn’t hard enough for someone without our medical condition’s. I too have degenerative spine disease from my neck to my tailbone. Also my bone are so brittle. Been going to the cancer center infusion center for just shy of 11 years. I fell stepping out of bed when my heart stopped broke legs and ankles now have titanium plates and six screws holding them together along with fiber tape for the leg bones. Plus I landed with my chin on my knees and broke 9 teeth. They want $70,000.00 for teeth. I qualified for die with dignity ( suicide at my home) . I pray for anyone who got started on these things and wants off. I can’t function without them and can function 2 hours a day with them that’s it. Been this way since I was 44 years old. God Bless you.
Hang in there. They need their grandma as long as possible 🙏🏼
I think this is a great video. Mainly cause of the visuals opiate receptor part. I’m a visual learner and it’s explained wonderfully
Your videos animation makes disease easy to understand
Really Nucleus medical media is the perfect platform for those students who loves physical biology too much.
And I am an Indian.
Love from India.
Love the simulations and right to the point explanations.
great job
right to the toilet for half of this yeah. is this aimed at kids or something? i dont get the point.
This was very basic and poorly narrated
You can say that again?
they left out a teeny-weeny bit of information sex
I’m glad my mom gave them to me when I was a child. she never gave me more than what the doctor said, and kept them away from me. so if I was sick, she was in control of my medicine intake
What a lovely animation and explanation I always watch your video for clearance of concepts
I'm so happy that I ended my oxycodone addiction alone... Willpower is the most important thing... The first month was the worst then it got better... Even though I still struggle with depression... And it all started with back surgery and pills called OXYNORM... I ate like candy, but after half a year I said enough and since August 2022 I am clean...
Hydrocodone was prescribed to my dad when he was going through chemo, my dad didn’t like taking them so I innocently started using them not knowing how addictive they were. This was back in 99 so the internet and information about these things were far more obscured. Thankfully I never went through major withdrawals but that was one substance that I really missed when I used them up. I didn’t realize how much I liked them until I didn’t have them, that gave me a profound realization that it was for my best interest that I didn’t pursue trying to get more illegally…it scared me.
Yeah you are extremely lucky it wasnt oxycodone cause youd 100% would have went through withdrawl. Hydrocodone is pretty tame and usually mixed with tylenol not impossible but alot harder to get truly addicted to those..youd got to be swallowing a dozen pills a day
They weren’t prescribed to you! you shouldn’t have taken your dads medication
"innocently started using them" don't you mean Recklessly...What makes you think you can use somebody's else's prescription. In fact I believe that's a misdemeanor
Why do some people experience euphoria from opioids and others don’t? I didn’t feel anything from opioids…
"innocently"
I've been on a pain management regimen for over a decade and thankfully I've never felt a euphoric sensation and therefore a temptation to take pain medication when not needed. I'm very grateful because I feel I would probably not be here today if not for the medication I take (potential chronic-pain induced suicide) and the fact that I'm not tempted to increase dosage (death by overdose). I've seen how it can destroy lives as well as prolong quality of life. My hope is that one day soon humanity will learn what makes people like myself react somehow differently to opioids and develop a pain solution that works for everyone in need without the risks of addiction and overdose.
Your lucky
My (was) Doctor, said “I can’t give you sleeping pills, they’re addictive”. 5 mins later he’s offering me painkillers (opioids). I said no thanks they’re addictive.
They make more money off commissions by prescribing opioids.
you could have had a great time
This person is lying. It is not 1991 anymore. You could get plutonium easier than opioids now. It is just really trendy for people to say they are easy to get because of the "opioid crisis" which is a cultural thing now and if you nod your head and say "hmmm yes i know about that" you seem wise. The people addicted are addicts who were prescribed years ago. Even if you need opioids for chronic pain doctors are unmercifully kicking these patients off them, thanks to addicts who abused the system and dealers. Cut the bs.. doctors rarely prescribe them anymore... Only for cancer and severe pain and not enough to for you to get addicted unless you abuse the prescribed dose.
That's totally incorrect. In Vancouver you can get dillies for two bucks a pop on the street. You could hear roughly 8 calls per 5 minutes for dillies on the downtown Eastside. A friend of mine and I counted as a gag.
@@Ziess1 that is off the street not doctors.. he said from his doctor ( you are a dillie).
People have this stupid idea you can walk into a doctor and get opioids easily. It isnt easy at all to get them off doctors... You cant even get them when you have real pain thanks to addicts abusing the system
It is legal to become addicted to OxyContin but not heroin. Simply because the later isn’t taxed. Food for thought.
Thank you for saying it
That's false. Heroin is deemed too dangerous to be used medically, so it is not used. Same with other drugs like crystal meth, LSD, and shrooms.
@@bagelboy310 all drugs are safe if used safely
@@aloedg3191 what do you mean?
@@bagelboy310 heroin and meth arent necessarily more dangerous than others. Meth is prescribed and is known as desoxyn. Heroin is occasionally used for pain relief. LSD and shrooms are some of the safest drugs that exist. your comment is false
I feel really sorry for everyone that get into accidents or have painful diseases and when they take opiod people call them junkies. If there's a way to cut off the pain transmitter I'm sure more people will prefer that.
I’m 28 and I was diagnosed with MS when I was 21. MS has eaten away at the protective coating of my lower back nerves, I now take only Tramadol for the pain and it’s a blessing. I hate being reliant on pain pills but I’m glad I have the chance to take theme
This is kinda easy to understand, this is worth to watch
Thank u so much for this amazing information it's very helpful to learn the consept ❤️👍🏻🤗🤗
Very informative, thank you!
About 2 and a half months ago I was going through the worst withdrawals ever, I was doing 5-6 fentanyl percs a day, I lost friends, ruined relationships, all because of my drug use. I decided I wanted to quit but I never could quit fully. I would do good for a moth or so then the mental withdrawals start to come, after the physical, and you just crave and crave them like never before. Suboxone saved my life, I’m now 2-3 month cleans and feeling the best I ever have. Thank you lord and the TH-cam community for getting me through one of the toughest times of my life
I have Lupus and Fibromyalgia! I refuse to take pain medication for these very reasons... please pray for me and everyone else in constant pain
I am so sorry you are going thru that.i have fibromyalgia and arthritis. I do understand. GOD bless you
I was given 4 bottles of oxycontin after brain surgery. When I finished the pain relief I was having bad withdrawals, called Doctor and was told because they were prescribed they could not help me 😕 had to find out from addicts how to deal with withdrawals. That was in the UK.
Oh man :(
That's kinda odd to me. Normally, a doctor would (and should) prescribe that kind of drugs in a form of "dosage plan" or schedule, starting with the minimum necessary dose for a couple of days, then increasing it in small amounts until achieving the desired effect and keeping that dose as low as possible, then as the cause of pain goes away (in your case, the wound healing) also the dose should be decreased to prevent the patient withdrawal effects.
So in a *very, very* hypothetic example instead of taking a full dose every day for 14 days you actually take 1/4 for 4 days, then 1/2 for 4 days, then 3/4 another 4 days, full dose 2 days (or as long as the medic deems necessary for a peak dose), then decrease the amounts by 1/4 every day or two until you no longer need the medication. Opioids are extremely addictive so healthcare personnel would usually have to be very careful with them.
It really sucks to know that was not the case with you 😟 But it's good to know you ended up alright 🙂
I’m so sorry for you Kat .
I hope the pan is all gone now and you’re well. 🤗
I got morphine when I removed my appendix. It was years ago and I still remember the high of the shot the game me at the ER it was amazing! I totally understand how easy it is to get addicted.
More psychiatry videos like this, please!
I am a disabled ex soldier and I am addicted to oxycodone co codamol due to chronic pain from my injuries trying to cope with pain is bad enough but when the drugs stop being as effective it’s hell all day every day love and joy from the UK
********. Thomas_cliton21. ********
Check him out ℹ info on iG☝️☝️☝️
such a great video. Very helpful to understand class. Thanks! - pharmD student.
I always watch your related videos after studying any topic in Biology. The explanation and animations both are, no doubt great! Keep creating such informative content!
Yeah you are right we all are neet aspirants
Same , but i m learning it so i can pass medical college in future and also assist my father and backup assistant and also about medical engineering
I love you
@@RK...49... simp
@@PRANAV_AKFF1306 ouyi
Nice medical animation keep it up!
These animations are amazing
Classifying dependency UNDER addiction is a giant mistake.
I miss my opioid addiction...
Me too
Right, they make life more manageable
Your animated video really very helpful too understand with visually
Thank you so much for this video.
Bucharest, Roumanie
I’ve been on fentanyl for 11 years and boy the damage it has done to me is unbelievable it’s been unmanaged I’m in constant pain cuz my body needs more got copd/ asthma goodness knows what it’s hiding my pain receptors have vanished I got a splinter in my finger got the tweezers out pulled it out it was like I chopped my finger off crazy my fentanyl patches are 50mg per hour constant eve gone over a few times rattled loads hate the drug can’t even eat normal just yogurts sweet things they won’t even try to get me off it should never have been put on it in the first place hugs and love to all stay safe and god bless ❤️
I recommend you hit up this legit plug they're very reliable ship to any location they got Fentanyl ketamine dmt,lsd,spores,microdose and other psychedelic stuffs
trippy_psyche1
They're on Instagram
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Very nice explains ,Thank you
Thank you lady robot, I learned a lot.
Nothing more personal than a robot voice.
Wow Gods amazing and detailed creation! 🙏🏼
I’ve been prescribed a couple of these. After my knee surgery, I took 1 during the first week when pain was at a high. Other than that one, I smoked weed through for pain and it did wonders. I rather smoke than pills.
Smoking made my pain worse. I had a bad trip, became paranoid on the pain and thought it would never go away. Worst 2 hours of my life...
@@rickstevenson267 yeah, it’s definitely not for everyone. My wife has bad anxiety, smoking makes it worse. I also have bad anxiety and weed is perfect for me.
You try CBD?
I wonder if it's possible to create that euphoria without drugs and have it be constant but I guess you would just grow accustomed to it and it wouldn't be euphoric anymore.
Yes it is very possible, learn to play a musical instrument. I am a born musician from a musical family, the only time I don't feel pain is when I practice or am performing. it takes my back and sciatica pain away like it never existed.
this video is breath taking. I litterally can't breath rn
*LONG LIVE NUCLEUS MEDICAL MEDIA* 🎉🎉
Do a video on panic attack disorder and how to control it in such a situation,please!!
0n ins
I’ve been on high opioids for 20 years. Such a shame they haven’t figured out a way to make a pain killer minus the addiction issues. Oxy I done in my opinion is the best pain killer out there, but it has a dark side u get addicted very quickly then it starts a hell cycle of trying to stay ahead of withdrawl symptoms that make u wanna die. It’s almost like the ppl who make these drugs don’t wanna look into that 🤔 no addiction less money made
It's actually impossible. Opioids - full or partial agonists - mainly bind to mu receptors to exert the pain-killing process, but alas, the same receptor is responsible for the pleasant effects, also for the partial agonists /antagonist buprenorphine. So there's no analgesia without( at least some) euphoria. The ideal opioid does not exist. You can try with Tapentadol, a stronger form of Tramadol. But they're not opioids properly. They have the same backbone of venlafaxine, an antidepressant, modified to target opioid receptors. But it's too weak if compared to Hydrocodone or Oxycodone. I'm an ex heroin addict, and after a long methadone treatment, I was put on oxycodone since 2013 because of chronic pain. I have have never abused it. I live in Italy and the doctors are more willing to prescribe 5mg or 10mg OxyContin. Pills sold in the street? There's no such thing here.
Didn't know this, thank you
This helped me sleep very quickly, great video 👍
I like how the video producer constantly blames the patient for their addiction or misuse even though doctors used to give these out like candy. A simple surgery and they prescribe you 2 bottles of 120 tabs.
But they're not blaming the patient though at most they said that misusing the drug leads to more chance of you beinng addicted. Stop trying push your views everywhere.
they do surgery and don't even give a single dose lmao
Everyone shares some responsibility
Companies greatly profit off of addicts. Where there is lots of money to be made morality goes out of the window for some companies.
@@markmayer3886 Where there is lots of money to be made morality goes out of the window -for some companies-
Please do one for Psychedelics!
Wow brilliant explanation
Thank you !
What about people that have never experienced euphoria after taking opioids?!? I’ve literally been prescribed each drug mentioned and never once gotten high or suffered from withdrawal when suddenly stopping taking them!!
Funny, how I am capable of having a full-time job and work with pain for decades, yet somehow I'm not responsible enough to have 4-5 painkillers a month. A little reprieve from relentless pain is not that much to ask out of life.
Agreed. I can choose to be a racecar driver or jump out of an airplane but I can't make my own decisions about my health and my body??!!
a very close family member of mine was prescribed oxy after a surgery in 2005. it didn’t take until 2019 for him to realize he had a problem. he one time came to my school for my house key to grab ‘tools’ when my mother was in charge of giving them to him in the correct dosages. now 4 years sober, even after losing his wife, he is still the best guy I’ve ever known. I got my grandpa back❤
These animation is so great.
Very interesting keep it up 👍👍👍🥰
Thanks to this channle i have awesome grades in school😄👍
That's great!
Ive been off drugs now for 16 yrs this month. (11-2006 to now 11-2022) I wouldn’t wish my worst enemy on dope, (aka heroin). I was turned onto heroin from using prescription drugs legally. I was a straight up, no nonsense guy. Never broke rules let alone break the law, until I turned to drugs. I was into boxing as a teen, and wrestled in middle school. One day at the gym, I broke my wrist, and the Dr prescribed a strong opioid. The feeling was amazing (at first). Then after a few weeks, to couple months, it turned into maintenance, just to stay functional. The high was gone, and the goal was not to allow my body to get sick, (aka go through withdraws).
I wanted to do special forces, then law enforcement, then be a detective, I dreamed it every day from the time I was a child. All my dreams went out the window the day I started drugs. I ended up getting a 5 year sentence for breaking the law to supply my drug habit. I did 3 1/2 years on that 5 yr sentence, and haven’t did drugs since my release in 2006, Im 42 now and not a day goes by I dont regret making the choice to switch from pills to heroin.
Im telling this story to try and persuade anyone from using drugs, DONT DO IT!! Its not worth it, no drug is.
Thanks you sir ❤️❤️
21+ years of opiod addiction. I'm 40. Iv heroin and fentynl. All cause doc put me on morphine as a 18 year old.
Such a good video
Morphine was not enough even though i hadn’t taken a single painkiller for years that’s how much damage i sustained
It only alters your perception of pain but doesn’t actually stop it..
It does if you use enough.
I take an NSAID with my opioid before bed. You're right; the opioid doesn't actually treat pain but the NSAID does.
It does stop the pain. Substance p and glutamate can't be released from the presynaptic terminal when the opioid receptor is activated. Lack of substance p and glutamate creates a strong analgesic effect.
I strongly feel that my opioid is my smart screen!
It should be.
I was prescribed oxycodone after a surgery. I took 1 pill and felt really tired. 0 experience of pleasure or feel-good chemicals. Just tired and zombie feeling. No idea how anyone could get addicted to that
Now I’m understanding the show!
Was expecting a Labrinth soundtrack to play
Very useful vedio , thank you teacher
Mann, that is so FUCKING GOOD!
Addiction and dependance can also cause organ damage. Especially liver and kidneys
That's really only the tylenol found in percocet and vicodon. Straight opiates like oxycodone or hydrocodone without tylenol is known to not cause damage to the liver
I’ve been on hydrocodone, oxy, and fentanyl (6yrs) for 9 yrs now. I’m not addicted to it but I can tell my body is dependent on it but it’s not that bad. I had to stop cold turkey when I stopped fentanyl and that was tough but you can do it if you’re strong enough.
Such a great channel because I can clarify all problems through us channel tq tq so much
So nice of you
I can’t help but feel for anyone who has legitimate pain and can’t get what they need.
Can someone explain how one crosses the line from dependency to addiction? What is the defining factor that makes these things different because they skipped over it in this video.
I would also like to know, because if you are dependent on something aren’t you by definition addicted to it?
I would imagine the emotional body being out of balance, pain, trauma, grief, anger etc, unresolved will remain in the body. Left unprocessed it will continue to feed; (low self worth, self harm, etc) addiction happens when you use opioids to block this pain rather than face it full on. To be dependent on a drug because it blocks the pain is understandable however, pain has a voice and if you listen very carefully it will lead you to where you have to go to heal...
I believe the difference is that dependency is being dependent on a substance to continue living normally but addiction is when you are dependent and taking a substance for pleasure instead of the intended purpose. Like let’s say someone has to take a opioid to control their pain and be able to go on with life things like getting out of bed, going to work, engaging with friends but then if that person doesn’t take the opioids they can’t do those things because they hurt to much they are stuck in bed, don’t go to work, stop talking to friends that is dependence. Another scenario let’s say a person is taking a opioid that was originally given for the treatment of pain but now their pain has gotten better, but they are still taking it not for pain relief, but for euphoria and entertainment and if they don’t take the opioid they can’t function not because of being in pain but because of other reasons that’s addiction. At least that’s my understanding of it.
Addiction is the loss of control of limiting the use. Dependence is when it's needed, but you have the ability to control how much you need and no more. I have an intrathecal pump that has a constant amount of Fentanyl and bupivacaine given to me. I also have a bolus device (a remote control) that I can use to administer medication every hour if I need to. If I use it every hour, my body will want it every hour, and it will cause me to go through withdrawals. I only use the bolus when I can no longer deal with the pain. If your Doctor prescribes you so many pain pills for the month, and you use them up the first week, you're addicted. If you can make them last the whole month, your dependence.
@@kenziealex3868 I like your definition, much better than mine.
The never ending withdrawals from it are a pure nightmare 😕
Ya
You have choices to do whatever you wanna do just know consequences are following you and the sequences are conning you. (It feels good to hear someone talking about drugs to educate) we learned what 2+2 was.
I’m allergic to one form of opioid so avoided them all for many years until I come off a bike quite badly, had endone and I’ve never felt so sick in my life, never again. Was prescribed only ten tablets, well 8 went in the bin.
I ❤️ opioids
As an 8 year veteran in the IV heroin scene, and now a methadone patient of 7 years, i've only lowered my tolerance from 120mg methadone to now 28mg. i'mm 30 and these opioids have controlled my life for longer than i remember. Please if your younger stay away from ALL opioids, but especially fentanyl.
Kratom is your best friend while getting clean. ❤️