Nucleophilic Aromatic Substitution - Benzyne Intermediate and Meisenheimer Complex

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  • เผยแพร่เมื่อ 30 พ.ย. 2024

ความคิดเห็น • 22

  • @Doc_McStuffins
    @Doc_McStuffins 5 ปีที่แล้ว +15

    You're my favorite chem guy. Thanks for all you do!!! You're consistently amazing.

  • @PunmasterSTP
    @PunmasterSTP 3 ปีที่แล้ว +4

    Meisenheimer? More like my, so much higher...in educational value than almost every other video on TH-cam. Thanks again so much for making and sharing these!

  • @scoobydoo02
    @scoobydoo02 6 ปีที่แล้ว +9

    Never quit. I love this!!!!

  • @tom_winguill
    @tom_winguill 4 ปีที่แล้ว +3

    9:40 3️⃣50 C

  • @raiyanrahman79
    @raiyanrahman79 3 ปีที่แล้ว

    In Chlorobenzene there should slight negative charges in Ortho and para position due to resonance. Then why does a Neucleophile attack the H in the ortho position? Wouldn't it make more sense if it attacked the H in meta position where the electron density is relatively lesser?

  • @Spogeboii
    @Spogeboii 5 ปีที่แล้ว +3

    Will NAS occur if there is an activating group and a good leaving group? Or is this process restricted to a deactivated ring and a nucleophilic reagent?

    • @ansingh1338
      @ansingh1338 4 ปีที่แล้ว +1

      Same doubt...

    • @PunmasterSTP
      @PunmasterSTP 3 ปีที่แล้ว

      Doesn't the reaction starting at 14:56 have an activating group (methyl) and a good leaving group (bromo)?

  • @gerstensaft2936
    @gerstensaft2936 6 ปีที่แล้ว +2

    In the last reaction. How's the ratio of meta to ortho and para? 1:2:1 (orto:meta:para)
    Or is para more likely to happen than ortho because of steric hindrance of the CH3 group?

    • @janrenehaak
      @janrenehaak 6 ปีที่แล้ว +1

      I think that the methyl-group isn´t so bulky, so their is no hindrance. Because of that I suggest, that the ratio ist 1:2:1 as you said. I hope this didn´t come too late :D

  • @alexfrostbound4401
    @alexfrostbound4401 2 ปีที่แล้ว

    You are a breathing miracle

  • @husseinfedilla6814
    @husseinfedilla6814 3 ปีที่แล้ว

    Beautiful

  • @1BigMan.Tshepo
    @1BigMan.Tshepo ปีที่แล้ว

    W video man, big up.

  • @musicmeister1313
    @musicmeister1313 3 ปีที่แล้ว

    ok, but what are the other reagents that can go through the benzyne intermediate 😠😠?

  • @deepamishal4683
    @deepamishal4683 4 ปีที่แล้ว +1

    17:30 which one is major and minor

  • @dathuyadav8822
    @dathuyadav8822 6 ปีที่แล้ว +1

    Nice

  • @VikasVerma-pn4rq
    @VikasVerma-pn4rq 3 ปีที่แล้ว +2

    Best video WhatsApps

  • @ramillucas2117
    @ramillucas2117 5 ปีที่แล้ว +1

    will you marry me? organic chemistry tutor? HAHAHAHA

    • @PunmasterSTP
      @PunmasterSTP 3 ปีที่แล้ว +1

      From your asking that question, I take it you two have chemistry together?

  • @crenapun57
    @crenapun57 3 ปีที่แล้ว +2

    tw