Infection risk associated with BTKIs in CLL: a meta-analysis of clinical trials

Barbara Eichhorst, MD, University Hospital Cologne, Cologne, Germany, discusses a meta-analysis of clinical trials examining the infection risk in patients with chronic lymphocytic leukemia (CLL) who were treated with BTK inhibitors (BTKIs). She notes a potential bias in the analysis, as higher-risk patients were more likely to receive BTKI-based treatments. However, Dr Eichhorst concludes that continuous therapy with BTKIs may have a cumulative infection risk due to long treatment durations. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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