Thyroid Hormone Synthesis

Thyroid hormone synthesis is a complex process involving both intracellular and extracellular components. This 7 min, 43 s video utilizes custom-designed animations and ADA-compliant closed captioning to helps students gain knowledge of this challenging topic. The video was designed to help students visualize the steps in thyroid hormone synthesis, including: 1. Iodide trapping 2. Oxidation of iodide 3. Synthesis of thyroglobulin 4. Iodination of tyrosine 5. Conjugation of T1 and T2 6. Endocytosis and digestion of colloid 7. Secretion of thyroid hormones 8. Conversion of T4 to T3 at target tissues 9.Binding of T3 to nuclear receptors

[@telatti]

this is the best video on thyroid synthesis, thank you! it’s been 6 years and i am always coming back to it when i need to refresh my memory. you did a great job :)

[@benjaminphillip9562]

Permanent cure to hypothyroidism with the help of Dr iyaremoses herbal medication no side effects#driyaremoses channel

[@BrainNP]

Thank you so much for this detailed visual, with an appropriate speaking pace to be able to have time to pause and rewind.

[@soukainaak2755]

i spend one hour on this course and i was so confused but now u have clarify it on only 7min thank u so much !!

[@dudedude9528]

the way you explained the process is truly amazing god bless you

[@bingobangobongo5]

Isn't this just incredible. Imagine the rate at which we can learn this kind of stuff as opposed to the years prior without the internet. The world is at our fingertips!

[@inderpreetsingh5736]

really best video on thyroid synthesis

[@tinaguicoMD]

Very helpful video! It summarizes several paragraphs from the lecture of Thyroid Gland. Thanks.

[@msgenevieveblais]

Honestly you have the best video online for this! Thanks :)
I only wish you would have gone into more detail about why the T3 and T4 need to be processed in the colloid space (as the reaction is very nasty and produces a lot of free radicals and need hydrogen peroxide which would wreak havoc on the cell). It would just help put the vid in perspective as why the rxn does not simply take place in the intracellular space and instead is done extracellularly. But really the vid is perfect thanks! Helped with my tutoring

[@arunteja1111]

very good video but oxidation of iodine occurs in the lumen as the thyroid peroxidase enzyme present on the apical membrane... iodine is carried to the lumen by the transporter ''pendrin''...then after peroxidase enzyme oxideses the iodine to hypoiodous acid or iodinium.....

[@MikaylaMurphy130]

Thank you so much! I has having difficulty understanding this in class and it was explained so clearly here. The animations and pictures were very helpful!

[@GR-bt3et]

EXCELLENT video with great graphics and explanation. I can now say I understand this topic. More like this please!

[@alisinan9934]

Best thyroid video ever!

[@nuveen60]

I am from India. Your video was very helpful in understanding the concept , during my preparation for PG medical entrance exam. Thank you very much

[@kylehallas2011]

nuveen60 good luck

[@lauraedwards7500]

good luck!

[@fastrack2170]

Thank you very much, it was difficult finding this. I've been taking nascent iodine and I needed to know how the procedure worked.

[@manjuprasad.m.k.kempraju2954]

Very good one, thanks for making thyroid understanding easy

[@anandmention3173]

so nice no any can explain like u , love from india,

[@dontjudgemeok9657]

I'm a 7th grader and i am researching this topic and you did a very good job at explaining the disease

[@erzasarlet6638]

it really helped simplify it!! Tho i study it in french i was able to perfectly understand! thank you very much!!

[@alidanai8218]

Thank you very much! Simple and Understandable! Good job!

[@jacobiniemem1930]

Thank you very much for your detailed information.

[@HillsideADAM]

Fantastic video, enjoyed learning about the Thyroid gland #MOT

[@alexanderdavy6205]

Fucking melt

[@sm9828]

absolutely fantastic and descriptive i could not thank you guys enough! much appreciated :D

[@meghnabose3303]

amazing video👍

[@aimansultana6855]

This work is really helpful... thank you !!!

[@hannakelawala8317]

nice video
thanks for sharing

[@namratakumar4887]

One of the best videos

[@saraessam6998]

very good animation... thanks

[@laibashahid9418]

outstanding video!....very helpful!

[@elixirs4491]

Thank u so much that was so helpful

[@hrnairutube]

Excellent animation and clear explanation. Thank you!!

[@Drisisv]

such an awesome video. Gracias!!!

[@yuniee100]

Thank you very much! it is an excellent explanation!!!!

[@zm5887]

Thanks Dr. Metz

[@danielal1100]

Great video! However, the thyroid receptor binds to DNA in the absence of the hormone and leads to transcriptional repression. Once T3 is bound, it causes a conformational change and becomes active, thus, causing transcription to occur.

[@vogelnjreri8248]

It can also bind as an heretodimere with the activated rxr-rezeptor to initiate transscription

[@vogelnjreri8248]

from my medicinal chemistry lecture :D

[@Msimmo35786]

Such a great video! Love your pace and explanation! Thanks!

[@channell1104]

Hi ! ,Amazing a wonderful presentation Thanks alot.

[@elwynbrooks]

The animation REALLY helps! Thank you!!

[@umaribrahim2115]

excellent explanation☺

[@Homo_sapien30]

Informative, and well explained

[@abdullahalmamun9259]

thnx mam... this is really so much helpful for us.

[@jorgeloroperez5267]

Very well explained! Great work!!

[@hassansoomro126]

very helpful video explain very well!******

[@LegendofA]

Thanks for the explanation!

[@مهندحسين-م2غ]

thanks you very much .

[@12parri]

Great video! Thanks so much!

[@paige0x18]

Thank you so very much for this.

[@kelseynaidoo9872]

Very informative, thank you.

[@divyaduggal5950]

Very well explained!

[@f3foodfunfacts886]

super and as simple as that,thnk u

[@30musabboouf61]

Thanks alot
Very helpful ❤️

[@TheRezhwanDrummer]

well done.

[@awaiskhandc4302]

awesome 😊👍👍

[@RomanEsposito-su3zm]

Best explanation ever thank you!

[@natalieadams4541]

SO helpful thank you!

[@blackyrocky7438]

Pendrin transporter transport iodide in to colloid where oxidation of iodide happens by thyroid peroxidase. And thyroid peroxidase also does iodination of thyroglobulin

[@jaquelinemanuel5716]

Thank you for a very clear explanation.

[@weissergspritzter]

Great explanation!

[@carlospradoguerrero]

Great! Tks a lot!

[@BIZIL91]

Gr8 video

[@afiicena4705]

really help with my medical study, thank you!!
wish me luck :)

[@بسمالله-ص5ن]

Afifah Mukhliza عفيفه
😂

[@drvaun81]

nice presentation thanks

[@حسنعليحسين-ز4ذ]

Excellent, thank you.

[@Fayezakureshi]

Very easily explained and understand

[@aqsaamin7607]

Nicely explained

[@alaamekky5840]

great video thank you really

[@VijayKumar-gu8yn]

Nice ❤️❤️❤️

[@majolaization]

thank you...

[@braindots2053]

Thank you so very much.

[@reenjalal6410]

Thanks for this nice presentation

[@بسمالله-ص5ن]

Reen Jalal الله عليج

[@RamanDeep-nt2yr]

thankyou soo much it helped me alott

[@monishkantymondal5527]

so useful❤❤❤

[@user-oo3fu3ms4o]

Thank you sooo much!!

[@amayafonseka4171]

Very nice

[@nekochan4595]

Helpful^.^
Thank you very much :)

[@janhavikulkarni3440]

Thank you so much...

[@janiesosa647]

thanks for this. I am very visual and just reading and following arrows is not always helpful.

[@varshavarghese8673]

Thank you so much maam.....

[@hadeelsami9107]

thank u ♡♡ u are awesome ♡

[@بسمالله-ص5ن]

Hadeel Sami هلا

[@nishajaswal5844]

Very helpful

[@lee11676]

How thyroixine act on the cell?

[@mohanned6963]

THANK YOU

[@AhmedMD]

Thank you !!!

[@megm2253]

thank u very helpful 😊

[@بسمالله-ص5ن]

meg m hello

[@levincaritan6855]

omg thank you so much for this!

[@christabelakerele5723]

This is just great! Are the slides available?

[@nehaanshu2597]

Thanks a lot...

[@3wordsoxforddaily786]

thank you so much

[@alikimiaei8004]

that was amazing

[@LiliaDiaz-bl4cx]

thank you!!!!!!!

[@hasnaasalama5535]

aweesooome thaaanks :D

[@hellomeme94]

thanks alot

[@kavyaviswanath9386]

helpful,thank u

[@azkarukanta3668]

Great video! It so much helps :)

[@Amurald]

OK..but what happens to the Na+
That enters the parafollicular cell

[@Shacni.]

Good dear💋

[@GoldenBoy1938]

So with Hashimoto's inflammation of the thyroid gland, this active tissue also breaks down, which means that fewer hormones can be produced and stored, right?

[@I34R]

please explain to me what the role of tyrosine is????

[@مرتضىنعمههادي]

Thank you so so so.... much

[@Toennesen]

From the DIET!!! :)

[@lauraedwards7500]

didnt mention the need of TSH from pars distalis of hypophysis to send the signal prior to secretion to happen